Joint stiffness
Symptom Information:
Symptom ID: | HPO:0001387 | ||||||||||||||||||||||||||||||||||||||
Synonyms: |
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Quality: | |||||||||||||||||||||||||||||||||||||||
Cross references: |
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Is a (Direct Parents): |
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Is a (Whole tree): |
HPO:
All(HPO:0000001) Phenotypic abnormality(HPO:0000118) Abnormality of the skeletal system(HPO:0000924) Abnormality of skeletal morphology(HPO:0011842) Abnormal joint morphology(HPO:0001367) Abnormality of joint mobility(HPO:0011729) Limitation of joint mobility(HPO:0001376) Joint stiffness(HPO:0001387) MedDRA: Musculoskeletal and connective tissue disorders(MedDRA:10028395) Joint disorders(MedDRA:10023213) Joint related signs and symptoms(MedDRA:10023226) Joint stiffness(HPO:0001387) |
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Database Frequency: | 322 / 7739 | ||||||||||||||||||||||||||||||||||||||
Resource: |
All diseases associated with this symptom:
17q23.1q23.2 microdeletion syndrome | (Orphanet:261279) |
3q13 microdeletion syndrome | (Orphanet:1621) |
8q22.1 microdeletion syndrome | (Orphanet:178303) |
Aase-Smith syndrome | (Orphanet:916) |
Achondroplasia | (Orphanet:15) |
Acromesomelic dysplasia, Grebe type | (Orphanet:2098) |
Acromesomelic dysplasia, Hunter-Thomson type | (Orphanet:968) |
Acromesomelic dysplasia, Maroteaux type | (Orphanet:40) |
Acromicric dysplasia | (Orphanet:969) |
Adult polyglucosan body disease | (Orphanet:206583) |
Alkaptonuria | (Orphanet:56) |
Allan-Herndon-Dudley syndrome | (Orphanet:59) |
Alopecia - contractures - dwarfism - intellectual deficit | (Orphanet:1005) |
Alpha-thalassemia - X-linked intellectual deficit syndrome | (Orphanet:847) |
Amish lethal microcephaly | (Orphanet:99742) |
Antecubital pterygium syndrome | (Orphanet:2987) |
Antley-Bixler syndrome | (Orphanet:83) |
Arthrogryposis - hyperkeratosis, lethal form | (Orphanet:1485) |
Arthrogryposis - renal dysfunction - cholestasis | (Orphanet:2697) |
Arthrogryposis due to muscular dystrophy | (Orphanet:1155) |
Arthrogryposis multiplex congenita - whistling face | (Orphanet:1150) |
Arthrogryposis with oculomotor limitation and electroretinal anomalies | (Orphanet:1154) |
Arthrogryposis-like hand anomaly - sensorineural deafness | (Orphanet:1144) |
Arthrogryposis-like syndrome | (Orphanet:1149) |
Aspartylglucosaminuria | (Orphanet:93) |
Atherosclerosis - deafness - diabetes - epilepsy - nephropathy | (Orphanet:1192) |
Atypical teratoid tumor | (Orphanet:99966) |
Autosomal dominant congenital benign spinal muscular atrophy | (Orphanet:1216) |
Autosomal dominant popliteal pterygium syndrome | (Orphanet:1300) |
Autosomal dominant striatal neurodegeneration | (Orphanet:228169) |
Autosomal recessive multiple pterygium syndrome | (Orphanet:2990) |
Autosomal recessive palmoplantar keratoderma and congenital alopecia | (Orphanet:1366) |
Babesiosis | (Orphanet:108) |
Baraitser-Winter syndrome | (Orphanet:2995) |
Bethlem myopathy | (Orphanet:610) |
Blau syndrome | (Orphanet:90340) |
Blepharophimosis - radioulnar synostosis | (Orphanet:1256) |
Bohring-Opitz syndrome | (Orphanet:97297) |
Bowen-Conradi syndrome | (Orphanet:1270) |
Brachydactyly - elbow wrist dysplasia | (Orphanet:1275) |
Brachydactyly-long thumb syndrome | (Orphanet:2946) |
Brachytelephalangy - dysmorphism - Kallmann syndrome | (Orphanet:1295) |
Bruck syndrome | (Orphanet:2771) |
Buschke-Ollendorff syndrome | (Orphanet:1306) |
C syndrome | (Orphanet:1308) |
CINCA syndrome | (Orphanet:1451) |
COFS syndrome | (Orphanet:1466) |
Camptodactyly - joint contractures - facial skeletal defects | (Orphanet:1323) |
Camurati-Engelmann disease | (Orphanet:1328) |
Cardiocranial syndrome, Pfeiffer type | (Orphanet:2872) |
Cardiomyopathy-cataract-hip spine disease | (Orphanet:1345) |
Cartilage-hair hypoplasia | (Orphanet:175) |
Catel-Manzke syndrome | (Orphanet:1388) |
Caudal regression sequence | (Orphanet:3027) |
Cerebrotendinous xanthomatosis | (Orphanet:909) |
Classical homocystinuria | (Orphanet:394) |
Cleft palate - short stature - vertebral anomalies | (Orphanet:2015) |
Cockayne syndrome | (Orphanet:191) |
Congenital contractural arachnodactyly | (Orphanet:115) |
Congenital muscular dystrophy due to LMNA mutation | (Orphanet:157973) |
Congenital unilateral hypoplasia of depressor anguli oris | (Orphanet:1166) |
Contractures - ectodermal dysplasia - cleft lip/palate | (Orphanet:1484) |
Cornelia de Lange syndrome | (Orphanet:199) |
Crane-Heise syndrome | (Orphanet:1512) |
Cranio-osteoarthropathy | (Orphanet:1525) |
Cryptorchidism - arachnodactyly - intellectual deficit | (Orphanet:1548) |
Cutis laxa-Marfanoid syndrome | (Orphanet:171719) |
Cyprus facial-neuromusculoskeletal syndrome | (Orphanet:2674) |
DWARFISM WITH STIFF JOINTS AND OCULAR ABNORMALITIES | (OMIM:127200) |
Dermato-cardio-skeletal syndrome, Borrone type | (Orphanet:1266) |
Desmoid tumor | (Orphanet:873) |
Diastrophic dwarfism | (Orphanet:628) |
Digitotalar dysmorphism | (Orphanet:1146) |
Distal monosomy 10p | (Orphanet:1580) |
Distal symphalangism | (Orphanet:3248) |
Distal trisomy 15q | (Orphanet:1707) |
Dracunculiasis | (Orphanet:231) |
Duchenne and Becker muscular dystrophy | (Orphanet:262) |
Dyggve-Melchior-Clausen disease | (Orphanet:239) |
Dysmorphism - short stature - deafness - disorder of sex development | (Orphanet:2282) |
Dysplasia epiphysealis hemimelica | (Orphanet:1822) |
Dyssegmental dysplasia, Silverman-Handmaker type | (Orphanet:1865) |
Edinburgh malformation syndrome | (Orphanet:1895) |
Ehlers-Danlos syndrome, arthrochalasic type | (Orphanet:1899) |
Ehlers-Danlos syndrome, dermatosparaxis type | (Orphanet:1901) |
Ehlers-Danlos syndrome, hypermobility type | (Orphanet:285) |
Emery-Dreifuss muscular dystrophy | (Orphanet:261) |
Enchondromatosis | (Orphanet:296) |
Epidermolysis bullosa simplex with pyloric atresia | (Orphanet:158684) |
Extensor tendons of finger anomalies | (Orphanet:3294) |
Eye defects - arachnodactyly - cardiopathy | (Orphanet:2725) |
Familial Dupuytren contracture | (Orphanet:79142) |
Familial articular chondrocalcinosis | (Orphanet:1416) |
Familial symmetric lipomatosis | (Orphanet:2398) |
Familial visceral myopathy | (Orphanet:2604) |
Farber lipogranulomatosis | (Orphanet:333) |
Felty syndrome | (Orphanet:47612) |
Fetal akinesia deformation sequence | (Orphanet:994) |
Fetal alcohol syndrome | (Orphanet:1915) |
Fibrodysplasia ossificans progressiva | (Orphanet:337) |
Fibular aplasia - complex brachydactyly | (Orphanet:2639) |
Floating-Harbor syndrome | (Orphanet:2044) |
Flynn-Aird syndrome | (Orphanet:2047) |
Focal myositis | (Orphanet:48918) |
Freeman-Sheldon syndrome | (Orphanet:2053) |
Frontometaphyseal dysplasia | (Orphanet:1826) |
GELEOPHYSIC DYSPLASIA 2 | (OMIM:614185) |
GM1 gangliosidosis | (Orphanet:354) |
GM1 gangliosidosis type 1 | (Orphanet:79255) |
Gaucher disease | (Orphanet:355) |
Geleophysic dysplasia | (Orphanet:2623) |
Generalized congenital lipodystrophy with myopathy | (Orphanet:228429) |
German syndrome | (Orphanet:2077) |
Giant cell arteritis | (Orphanet:397) |
Glaucoma - ectopia - microspherophakia - stiff joints - short stature | (Orphanet:2084) |
Gordon syndrome | (Orphanet:376) |
Hall-Riggs syndrome | (Orphanet:2107) |
Harlequin ichthyosis | (Orphanet:457) |
Heart-hand syndrome type 2 | (Orphanet:1350) |
Hemochromatosis type 4 | (Orphanet:139491) |
Hereditary hyperekplexia | (Orphanet:3197) |
Holzgreve-Wagner-Rehder syndrome | (Orphanet:2167) |
Humero-radial synostosis | (Orphanet:3265) |
Humerus trochlea aplasia | (Orphanet:3383) |
Hurler syndrome | (Orphanet:93473) |
Hurler-Scheie syndrome | (Orphanet:93476) |
Hydrocephalus with stenosis of aqueduct of Sylvius | (Orphanet:2182) |
Hyperimmunoglobulinemia D with periodic fever | (Orphanet:343) |
Hypomyelination neuropathy - arthrogryposis | (Orphanet:2680) |
Hypophosphatemic rickets | (Orphanet:437) |
Hypoplastic tibiae - postaxial polydactyly | (Orphanet:3332) |
Hypospadias - intellectual deficit, Goldblatt type | (Orphanet:2261) |
IVIC syndrome | (Orphanet:2307) |
Infantile myofibromatosis | (Orphanet:2591) |
Intellectual deficit - balding - patella luxation - acromicria | (Orphanet:3041) |
Intellectual deficit - cataracts - calcified pinnae - myopathy | (Orphanet:3042) |
Intellectual deficit - myopathy - short stature - endocrine defect | (Orphanet:3068) |
Intellectual deficit, Wolff type | (Orphanet:3080) |
Intellectual disability-developmental delay-contractures syndrome | (Orphanet:3454) |
Isolated cloverleaf skull syndrome | (Orphanet:2343) |
Isolated ectopia lentis | (Orphanet:1885) |
Isolated osteopoikilosis | (Orphanet:166119) |
Junctional epidermolysis bullosa | (Orphanet:305) |
Juvenile dermatomyositis | (Orphanet:93672) |
Juvenile hyaline fibromatosis | (Orphanet:2028) |
Juvenile idiopathic arthritis | (Orphanet:92) |
Juvenile rheumatoid factor-negative polyarthritis | (Orphanet:85408) |
Juvenile rheumatoid factor-positive polyarthritis | (Orphanet:85435) |
KNIEST-LIKE DYSPLASIA WITH PURSED LIPS AND ECTOPIA LENTIS | (OMIM:245160) |
Kienbock disease | (Orphanet:97332) |
Kleefstra syndrome | (Orphanet:261494) |
Kniest dysplasia | (Orphanet:485) |
Kyphomelic dysplasia | (Orphanet:1801) |
Laurin-Sandrow syndrome | (Orphanet:2378) |
Lenz-Majewski hyperostotic dwarfism | (Orphanet:2658) |
Leri pleonosteosis | (Orphanet:2900) |
Lethal congenital contracture syndrome type 1 | (Orphanet:1486) |
Lethal multiple pterygium syndrome | (Orphanet:33108) |
Lethal recessive chondrodysplasia | (Orphanet:1423) |
Lethal restrictive dermopathy | (Orphanet:1662) |
Lipodystrophy due to peptidic growth factors deficiency | (Orphanet:1979) |
Lowry-Wood syndrome | (Orphanet:1824) |
Léri-Weill dyschondrosteosis | (Orphanet:240) |
MUCOLIPIDOSIS III GAMMA | (OMIM:252605) |
Madelung deformity | (Orphanet:35688) |
Malignant hyperthermia - arthrogryposis - torticollis | (Orphanet:2215) |
Mandibuloacral dysplasia | (Orphanet:2457) |
Mandibuloacral dysplasia with type A lipodystrophy | (Orphanet:90153) |
Marden-Walker syndrome | (Orphanet:2461) |
Marfan syndrome | (Orphanet:558) |
Maternal hyperthermia induced birth defects | (Orphanet:2216) |
Melorheostosis | (Orphanet:2485) |
Mesomelia-synostoses syndrome | (Orphanet:2496) |
Mesomelic dwarfism, Nievergelt type | (Orphanet:2633) |
Metachromatic leukodystrophy | (Orphanet:512) |
Metaphyseal anadysplasia | (Orphanet:1040) |
Metaphyseal chondrodysplasia, Jansen type | (Orphanet:33067) |
Metatropic dysplasia | (Orphanet:2635) |
Micro syndrome | (Orphanet:2510) |
Microcephaly - cardiac defect - lung malsegmentation | (Orphanet:2516) |
Microcephaly - intellectual deficit - phalangeal and neurological anomalies | (Orphanet:137658) |
Microphthalmia - microtia - fetal akinesia | (Orphanet:2547) |
Mietens syndrome | (Orphanet:2557) |
Mild spondyloepiphyseal dysplasia due to COL2A1 mutation with early-onset osteoarthritis | (Orphanet:93279) |
Mixed connective tissue disease | (Orphanet:809) |
Monosomy 9p | (Orphanet:261112) |
Morse-Rawnsley-Sargent syndrome | (Orphanet:2570) |
Mosaic trisomy 8 | (Orphanet:96061) |
Mosaic trisomy 9 | (Orphanet:99776) |
Mucolipidosis type 3 | (Orphanet:577) |
Mucopolysaccharidosis type 1 | (Orphanet:579) |
Mucopolysaccharidosis type 2 | (Orphanet:580) |
Mucopolysaccharidosis type 2, severe form | (Orphanet:217085) |
Mucopolysaccharidosis type 3 | (Orphanet:581) |
Mucopolysaccharidosis type 6 | (Orphanet:583) |
Mucopolysaccharidosis type 7 | (Orphanet:584) |
Multicentric carpo-tarsal osteolysis with or without nephropathy | (Orphanet:2774) |
Multifocal muscular fibrosis - obstructed vessels | (Orphanet:2033) |
Multiminicore myopathy | (Orphanet:598) |
Multiple epiphyseal dysplasia | (Orphanet:251) |
Multiple epiphyseal dysplasia due to collagen 9 anomaly | (Orphanet:166002) |
Multiple epiphyseal dysplasia type 1 | (Orphanet:93308) |
Multiple epiphyseal dysplasia type 5 | (Orphanet:93311) |
Multiple sulfatase deficiency | (Orphanet:585) |
Multiple synostoses syndrome | (Orphanet:3237) |
Mutilating palmoplantar keratoderma with periorificial keratotic plaques | (Orphanet:659) |
Myalgia-eosinophilia syndrome associated with tryptophan | (Orphanet:2582) |
Myhre syndrome | (Orphanet:2588) |
Myotonia permanens | (Orphanet:99735) |
Nager syndrome | (Orphanet:245) |
Nail-patella syndrome | (Orphanet:2614) |
Nakajo-Nishimura syndrome | (Orphanet:2615) |
Nasu-Hakola disease | (Orphanet:2770) |
Nephrogenic diabetes insipidus - intracranial calcification | (Orphanet:3145) |
Nestor-Guillermo progeria syndrome | (Orphanet:280576) |
Neurofibromatosis type 1 | (Orphanet:636) |
Neurogenic arthrogryposis multiplex congenita | (Orphanet:1143) |
Non-rhizomelic chondrodysplasia punctata | (Orphanet:176) |
OSLAM syndrome | (Orphanet:2760) |
OSTEOARTHRITIS SUSCEPTIBILITY 3 | (OMIM:607850) |
Oculocerebral hypopigmentation syndrome, Cross type | (Orphanet:2719) |
Oculocerebral hypopigmentation syndrome, Preus type | (Orphanet:2720) |
Oculocerebrorenal syndrome | (Orphanet:534) |
Ophthalmomandibulomelic dysplasia | (Orphanet:2741) |
Opsismodysplasia | (Orphanet:2746) |
Osteochondrodysplatic nanism - deafness - retinitis pigmentosa | (Orphanet:2653) |
Oto-onycho-peroneal syndrome | (Orphanet:2793) |
Otopalatodigital syndrome | (Orphanet:669) |
Otopalatodigital syndrome type 1 | (Orphanet:90650) |
Otospondylomegaepiphyseal dysplasia | (Orphanet:1427) |
PEHO syndrome | (Orphanet:2836) |
PHAVER syndrome | (Orphanet:2876) |
Pachydermoperiostosis | (Orphanet:2796) |
Parana hard-skin syndrome | (Orphanet:2812) |
Parastremmatic dwarfism | (Orphanet:2646) |
Pelizaeus-Merzbacher disease | (Orphanet:702) |
Pelvic dysplasia - arthrogryposis of lower limbs | (Orphanet:2840) |
Peripheral dysostosis | (Orphanet:1795) |
Peripheral motor neuropathy - dysautonomia | (Orphanet:2400) |
Permanent neonatal diabetes mellitus - pancreatic and cerebellar agenesis | (Orphanet:65288) |
Pfeiffer syndrome type 2 | (Orphanet:93259) |
Pfeiffer syndrome type 3 | (Orphanet:93260) |
Pfeiffer-Palm-Teller syndrome | (Orphanet:2871) |
Pontocerebellar hypoplasia type 1 | (Orphanet:2254) |
Posterior fusion of lumbosacral vertebrae - blepharoptosis | (Orphanet:2064) |
Potassium-aggravated myotonia | (Orphanet:612) |
Progeria - short stature - pigmented nevi | (Orphanet:2959) |
Progressive non-infectious anterior vertebral fusion | (Orphanet:2062) |
Progressive osseous heteroplasia | (Orphanet:2762) |
Progressive pseudorheumatoid arthropathy of childhood | (Orphanet:1159) |
Proteus syndrome | (Orphanet:744) |
Proximal spinal muscular atrophy | (Orphanet:70) |
Pseudoachondroplasia | (Orphanet:750) |
Pyogenic arthritis - pyoderma gangrenosum - acne | (Orphanet:69126) |
Reactive arthritis | (Orphanet:29207) |
Relapsing polychondritis | (Orphanet:728) |
Renpenning syndrome | (Orphanet:3242) |
Rett syndrome | (Orphanet:778) |
Rhizomelic chondrodysplasia punctata | (Orphanet:177) |
Rhizomelic syndrome, Urbach type | (Orphanet:3098) |
Richards-Rundle syndrome | (Orphanet:1399) |
Rift valley fever | (Orphanet:319251) |
Rothmund-Thomson syndrome | (Orphanet:2909) |
STING-ASSOCIATED VASCULOPATHY, INFANTILE-ONSET | (OMIM:615934) |
SYNDESMODYSPLASIC DWARFISM | (OMIM:272450) |
Sanfilippo syndrome type A | (Orphanet:79269) |
Sanfilippo syndrome type B | (Orphanet:79270) |
Sanfilippo syndrome type C | (Orphanet:79271) |
Sanfilippo syndrome type D | (Orphanet:79272) |
Say-Barber-Miller syndrome | (Orphanet:3132) |
Scheie syndrome | (Orphanet:93474) |
Schwartz-Jampel syndrome | (Orphanet:800) |
Self-healing collodion baby | (Orphanet:281122) |
Severe X-linked intellectual deficit, Gustavson type | (Orphanet:3078) |
Sheldon-Hall syndrome | (Orphanet:1147) |
Short stature - craniofacial anomalies - genital hypoplasia | (Orphanet:2994) |
Shoulder and thorax deformity - congenital heart disease | (Orphanet:1940) |
Shprintzen-Goldberg syndrome | (Orphanet:2462) |
Sjögren-Larsson syndrome | (Orphanet:816) |
Smith-Magenis syndrome | (Orphanet:819) |
Spastic paraplegia type 2 | (Orphanet:99015) |
Spondylocarpotarsal synostosis | (Orphanet:3275) |
Spondyloepimetaphyseal dysplasia, Irapa type | (Orphanet:93351) |
Spondyloepimetaphyseal dysplasia, Missouri type | (Orphanet:93356) |
Spondyloepiphyseal dysplasia congenita | (Orphanet:94068) |
Spondylometaphyseal dysplasia - cone-rod dystrophy | (Orphanet:85167) |
Spondylometaphyseal dysplasia, A4 type | (Orphanet:168555) |
Spondylometaphyseal dysplasia, Kozlowski type | (Orphanet:93314) |
Spondyloperipheral dysplasia - short ulna | (Orphanet:1856) |
Stiff skin syndrome | (Orphanet:2833) |
Stoll-Alembik-Finck syndrome | (Orphanet:3200) |
Stüve-Wiedemann syndrome | (Orphanet:3206) |
Suarez-Stickler syndrome | (Orphanet:166277) |
Syndactyly type 4 | (Orphanet:93405) |
Thanatophoric dysplasia | (Orphanet:2655) |
Thanatophoric dysplasia type 1 | (Orphanet:1860) |
Thanatophoric dysplasia type 2 | (Orphanet:93274) |
Thiemann disease, familial form | (Orphanet:3314) |
Thumb stiffness - brachydactyly - intellectual deficit | (Orphanet:1078) |
Thymoma | (Orphanet:99867) |
Tibial aplasia - ectrodactyly | (Orphanet:3329) |
Torg-Winchester syndrome | (Orphanet:3460) |
Transgrediens et progrediens palmoplantar keratoderma | (Orphanet:495) |
Trismus - pseudocamptodactyly | (Orphanet:3377) |
Trisomy 17p | (Orphanet:261290) |
Trisomy 8q | (Orphanet:1752) |
Trisomy Xq28 | (Orphanet:1762) |
Ulna hypoplasia - intellectual deficit | (Orphanet:2249) |
Upington disease | (Orphanet:3408) |
Van den Ende-Gupta syndrome | (Orphanet:2460) |
Vici syndrome | (Orphanet:1493) |
WEILL-MARCHESANI SYNDROME 1 | (OMIM:277600) |
WEILL-MARCHESANI SYNDROME 3 | (OMIM:614819) |
Waardenburg syndrome type 3 | (Orphanet:896) |
Weaver syndrome | (Orphanet:3447) |
Weill-Marchesani syndrome | (Orphanet:3449) |
Werner syndrome | (Orphanet:902) |
Wiedemann-Rautenstrauch syndrome | (Orphanet:3455) |
Williams syndrome | (Orphanet:904) |
Wilson disease | (Orphanet:905) |
Wolfram syndrome | (Orphanet:3463) |
X-linked distal arthrogryposis multiplex congenita | (Orphanet:1145) |