Juvenile idiopathic arthritis
General Information (adopted from Orphanet):
| Synonyms, Signs: |
Juvenile chronic arthritis Juvenile rheumatoid arthritis |
| Number of Symptoms | 27 |
| OrphanetNr: | 92 |
| OMIM Id: |
|
| ICD-10: |
M08 |
| UMLs: |
C0553662 C1444838 |
| MeSH: |
D001171 |
| MedDRA: |
10059177 |
| Snomed: |
239796000 410502007 410793008 410795001 |
Prevalence, inheritance and age of onset:
| Prevalence: | No data available. |
| Inheritance: |
|
| Age of onset: |
Childhood [Orphanet] |
Disease classification (adopted from Orphanet):
| Parent Diseases: |
Rare rheumatologic disease
-Rare systemic or rheumatologic disease Secondary interstitial lung disease specific to childhood associated with a connective tissue disease -Rare respiratory disease |
Symptom Information:
|
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(HPO:0000795) | Abnormality of the urethra | Frequent [Orphanet] | 38 / 7739 | |||
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(HPO:0100533) | Inflammatory abnormality of the eye | Frequent [Orphanet] | 70 / 7739 | |||
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(HPO:0001387) | Joint stiffness | Frequent [Orphanet] | 322 / 7739 | |||
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(HPO:0100773) | Cartilage destruction | Frequent [Orphanet] | 7 / 7739 | |||
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(HPO:0100550) | Tendon rupture | Very frequent [Orphanet] | 17 / 7739 | |||
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(HPO:0001373) | Joint dislocation | Frequent [Orphanet] | 59 / 7739 | |||
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(HPO:0001367) | Abnormal joint morphology | Frequent [Orphanet] | 53 / 7739 | |||
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(HPO:0100781) | Abnormality of the sacroiliac joint | Frequent [Orphanet] | 6 / 7739 | |||
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(HPO:0100769) | Synovitis | Very frequent [Orphanet] | 86 / 7739 | |||
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(HPO:0005059) | Arthralgia/arthritis | Very frequent [Orphanet] | 141 / 7739 | |||
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(HPO:0002024) | Malabsorption | Frequent [Orphanet] | 142 / 7739 | |||
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(HPO:0002240) | Hepatomegaly | Occasional [Orphanet] | 467 / 7739 | |||
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(HPO:0001744) | Splenomegaly | Occasional [Orphanet] | 337 / 7739 | |||
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(HPO:0002027) | Abdominal pain | Frequent [Orphanet] | 184 / 7739 | |||
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(HPO:0001072) | Thickened skin | Frequent [Orphanet] | 87 / 7739 | |||
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(HPO:0000988) | Skin rash | Frequent [Orphanet] | 98 / 7739 | |||
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(HPO:0001803) | Nail pits | Frequent [Orphanet] | 17 / 7739 | |||
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(HPO:0003765) | Psoriasis | Frequent [Orphanet] | 17 / 7739 | |||
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(HPO:0001597) | Abnormality of the nail | Frequent [Orphanet] | 115 / 7739 | |||
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(HPO:0000962) | Hyperkeratosis | Frequent [Orphanet] | 216 / 7739 | |||
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(HPO:0001805) | Thick nail | Frequent [Orphanet] | 96 / 7739 | |||
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(HPO:0001697) | Abnormality of the pericardium | Occasional [Orphanet] | 52 / 7739 | |||
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(HPO:0001945) | Fever | Very frequent [Orphanet] | 218 / 7739 | |||
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(HPO:0011227) | Elevated C-reactive protein level | Frequent [Orphanet] | 55 / 7739 | |||
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(HPO:0002103) | Abnormality of the pleura | Frequent [Orphanet] | 58 / 7739 | |||
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(HPO:0002960) | Autoimmunity | Very frequent [Orphanet] | 78 / 7739 | |||
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(HPO:0100721) | Mediastinal lymphadenopathy | Frequent [Orphanet] | 19 / 7739 |
Associated genes:
ClinVar (via SNiPA)
| Gene symbol | Variation | Clinical significance | Reference |
|---|