Juvenile rheumatoid factor-positive polyarthritis
General Information (adopted from Orphanet):
Synonyms, Signs:
|
Polyarthritis with rheumatoid factor
|
Number of Symptoms
|
8
|
OrphanetNr:
|
85435
|
OMIM Id:
|
|
ICD-10:
|
M08.0
|
UMLs:
|
|
MeSH:
|
|
MedDRA:
|
|
Snomed:
|
|
Prevalence, inheritance and age of onset:
Prevalence:
|
4.2
of 100 000
[Orphanet]
|
Inheritance:
|
Unknown
[Orphanet]
|
Age of onset:
|
Childhood
[Orphanet]
|
Disease classification (adopted from Orphanet):
Parent Diseases:
|
No data available.
|
|
|
|
|
|
|
|
|
1
|
(HPO:0000164)
|
Abnormality of the teeth |
Frequent [Orphanet]
|
|
|
|
291 / 7739
|
2
|
(HPO:0000277)
|
Abnormality of the mandible |
Frequent [Orphanet]
|
|
|
|
394 / 7739
|
3
|
(HPO:0005059)
|
Arthralgia/arthritis |
Very frequent [Orphanet]
|
|
|
|
141 / 7739
|
4
|
(HPO:0001367)
|
Abnormal joint morphology |
Very frequent [Orphanet]
|
|
|
|
53 / 7739
|
5
|
(HPO:0001387)
|
Joint stiffness |
Very frequent [Orphanet]
|
|
|
|
322 / 7739
|
6
|
(HPO:0100769)
|
Synovitis |
Very frequent [Orphanet]
|
|
|
|
86 / 7739
|
7
|
(HPO:0011227)
|
Elevated C-reactive protein level |
Very frequent [Orphanet]
|
|
|
|
55 / 7739
|
8
|
(HPO:0002960)
|
Autoimmunity |
Occasional [Orphanet]
|
|
|
|
78 / 7739
|
ClinVar (via SNiPA)
Gene symbol |
Variation |
Clinical significance |
Reference |