Malar flattening
Symptom Information:
Symptom ID: | HPO:0000272 | ||||||||||
Synonyms: |
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Quality: | |||||||||||
Cross references: |
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Is a (Direct Parents): |
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Is a (Whole tree): |
HPO:
All(HPO:0000001) Phenotypic abnormality(HPO:0000118) Abnormality of head or neck(HPO:0000152) Abnormality of the head(HPO:0000234) Abnormality of the face(HPO:0000271) Abnormal facial shape(HPO:0001999) Malar flattening(HPO:0000272) Abnormality of the midface(HPO:0000309) Abnormality of the zygomatic arch(HPO:0005557) Malar flattening(HPO:0000272) Abnormality of malar bones(HPO:0012369) Malar flattening(HPO:0000272) MedDRA: |
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Database Frequency: | 277 / 7739 | ||||||||||
Resource: |
All diseases associated with this symptom:
16p13.3 microduplication syndrome | (Orphanet:96078) |
17q11.2 microduplication syndrome | (Orphanet:139474) |
17q12 microdeletion syndrome | (Orphanet:261265) |
1p36 deletion syndrome | (Orphanet:1606) |
20p12.3 microdeletion syndrome | (Orphanet:261295) |
22q11.2 deletion syndrome | (Orphanet:567) |
2q32q33 microdeletion syndrome | (Orphanet:251019) |
2q37 microdeletion syndrome | (Orphanet:1001) |
3M syndrome | (Orphanet:2616) |
ACRODYSOSTOSIS 2 WITH OR WITHOUT HORMONE RESISTANCE | (OMIM:614613) |
ANTLEY-BIXLER SYNDROME WITH GENITAL ANOMALIES AND DISORDERED STEROIDOGENESIS | (OMIM:201750) |
ATP-BINDING CASSETTE, SUBFAMILY D, MEMBER 3 | (OMIM:170995) |
AXENFELD-RIEGER ANOMALY WITH PARTIALLY ABSENT EYE MUSCLES, DISTINCTIVEFACE, HYDROCEPHALY, AND SKELETAL ABNORMALITIES | (OMIM:109120) |
AXENFELD-RIEGER SYNDROME, TYPE 3 | (OMIM:602482) |
Ablepharon macrostomia syndrome | (Orphanet:920) |
Abruzzo-Erickson syndrome | (Orphanet:921) |
Achondrogenesis type 1B | (Orphanet:93298) |
Achondroplasia | (Orphanet:15) |
Acro-fronto-facio-nasal dysostosis | (Orphanet:1784) |
Acrofacial dysostosis, Catania type | (Orphanet:1786) |
Acrofacial dysostosis, Palagonia type | (Orphanet:1787) |
Acrofacial dysostosis, Rodriguez type | (Orphanet:1788) |
Acroosteolysis, dominant type | (Orphanet:955) |
Allan-Herndon-Dudley syndrome | (Orphanet:59) |
Alpha-mannosidosis | (Orphanet:61) |
Alpha-thalassemia - X-linked intellectual deficit syndrome | (Orphanet:847) |
Antley-Bixler syndrome | (Orphanet:83) |
Aortic arch anomaly - peculiar facies - intellectual deficit | (Orphanet:1110) |
Apert syndrome | (Orphanet:87) |
Arachnodactyly - abnormal ossification - intellectual deficit | (Orphanet:1129) |
Arterial tortuosity syndrome | (Orphanet:3342) |
Atelosteogenesis type I | (Orphanet:1190) |
Atelosteogenesis type II | (Orphanet:56304) |
Atelosteogenesis type III | (Orphanet:56305) |
Autosomal dominant Larsen syndrome | (Orphanet:503) |
Autosomal dominant Robinow syndrome | (Orphanet:3107) |
Autosomal recessive Robinow syndrome | (Orphanet:1507) |
Autosomal recessive cutis laxa type 2A | (Orphanet:357058) |
Autosomal recessive cutis laxa type 2B | (Orphanet:357064) |
Autosomal recessive omodysplasia | (Orphanet:93329) |
Autosomal recessive severe congenital neutropenia due to G6PC3 deficiency | (Orphanet:331176) |
BARATELA-SCOTT SYNDROME | (OMIM:300881) |
Beckwith-Wiedemann syndrome due to 11p15 microdeletion | (Orphanet:231127) |
Blepharophimosis-intellectual deficit syndrome, Verloes type | (Orphanet:293725) |
Bloom syndrome | (Orphanet:125) |
Brachymorphism - onychodysplasia - dysphalangism | (Orphanet:1292) |
Brachytelephalangy - dysmorphism - Kallmann syndrome | (Orphanet:1295) |
Branchio-oculo-facial syndrome | (Orphanet:1297) |
CAMPTODACTYLY SYNDROME, GUADALAJARA, TYPE III | (OMIM:611929) |
CATARACTS, CONGENITAL, WITH SENSORINEURAL DEAFNESS, DOWN SYNDROME-LIKEFACIAL APPEARANCE, SHORT STATURE, AND MENTAL RETARDATION | (OMIM:601088) |
CHARGE syndrome | (Orphanet:138) |
CK syndrome | (Orphanet:251383) |
CRANIOMETADIAPHYSEAL DYSPLASIA | (OMIM:269300) |
CRANIOSYNOSTOSIS-MENTAL RETARDATION SYNDROME OF LIN AND GETTIG | (OMIM:218649) |
Camptodactyly syndrome, Guadalajara type 1 | (Orphanet:1327) |
Cardiodysrhythmic potassium-sensitive periodic paralysis | (Orphanet:37553) |
Cardiofaciocutaneous syndrome | (Orphanet:1340) |
Carpenter syndrome | (Orphanet:65759) |
Cataract - intellectual deficit - hypogonadism | (Orphanet:1387) |
Cenani-Lenz syndrome | (Orphanet:3258) |
Cerebro-costo-mandibular syndrome | (Orphanet:1393) |
Cerebro-facio-articular syndrome | (Orphanet:314679) |
Cerebro-oculo-nasal syndrome | (Orphanet:66625) |
Chondrodysplasia punctata, tibial-metacarpal type | (Orphanet:79346) |
Chondrodysplasia, Blomstrand type | (Orphanet:50945) |
Cleft lip/palate - intestinal malrotation - cardiopathy | (Orphanet:2001) |
Cleidocranial dysplasia | (Orphanet:1452) |
Cohen syndrome | (Orphanet:193) |
Congenital lactic acidosis, Saguenay-Lac-St. Jean type | (Orphanet:70472) |
Congenital pulmonary lymphangiectasia | (Orphanet:2414) |
Connective tissue disorder due to lysyl hydroxylase-3 deficiency | (Orphanet:300284) |
Corneal anesthesia - deafness - intellectual deficit | (Orphanet:1051) |
Craniofacial dyssynostosis | (Orphanet:1516) |
Craniofacial-deafness-hand syndrome | (Orphanet:1529) |
Craniolenticulosutural dysplasia | (Orphanet:50814) |
Craniometadiaphyseal dysplasia, wormian bone type | (Orphanet:85184) |
Craniosynostosis - anal anomalies - porokeratosis | (Orphanet:85199) |
Cutis gyrata - acanthosis nigricans - craniosynostosis | (Orphanet:1555) |
Cutis laxa with severe pulmonary, gastrointestinal and urinary anomalies | (Orphanet:221145) |
DIAMOND-BLACKFAN ANEMIA 10 | (OMIM:613309) |
Deafness - intellectual deficit, Martin-Probst type | (Orphanet:85321) |
Desbuquois syndrome | (Orphanet:1425) |
Dislocation of the hip - dysmorphism | (Orphanet:2412) |
Distal 22q11.2 microdeletion syndrome | (Orphanet:261330) |
Distal monosomy 6p | (Orphanet:96125) |
Donnai-Barrow syndrome | (Orphanet:2143) |
Down syndrome | (Orphanet:870) |
Dysmorphism - pectus carinatum - joint laxity | (Orphanet:2104) |
Dysostosis, Stanescu type | (Orphanet:1798) |
Dyssegmental dysplasia - glaucoma | (Orphanet:1804) |
Dyssegmental dysplasia, Rolland-Desbuquois type | (Orphanet:156731) |
Dyssegmental dysplasia, Silverman-Handmaker type | (Orphanet:1865) |
ECTODERMAL DYSPLASIA SYNDROME WITH DISTINCTIVE FACIAL APPEARANCE ANDPREAXIAL POLYDACTYLY OF FEET | (OMIM:129540) |
ECTODERMAL DYSPLASIA, SENSORINEURAL HEARING LOSS, AND DISTINCTIVEFACIAL FEATURES | (OMIM:609944) |
ECTRODACTYLY, ECTODERMAL DYSPLASIA, AND CLEFT LIP/PALATE SYNDROME3 | (OMIM:604292) |
EEC syndrome | (Orphanet:1896) |
Ectodermal dysplasia - intellectual deficit - central nervous system malformation | (Orphanet:1812) |
Ehlers-Danlos syndrome, arthrochalasic type | (Orphanet:1899) |
Emery-Nelson syndrome | (Orphanet:1927) |
Endocrine-cerebro-osteodysplasia syndrome | (Orphanet:199332) |
FGFR2-related bent bone dysplasia | (Orphanet:313855) |
FIBROCHONDROGENESIS 2 | (OMIM:614524) |
Facial dysmorphism - immunodeficiency - livedo - short stature | (Orphanet:352712) |
Facial dysmorphism - shawl scrotum - joint laxity | (Orphanet:1778) |
Faciocardiorenal syndrome | (Orphanet:1973) |
Familial lambdoid synostosis | (Orphanet:3267) |
Familial osteodysplasia, Anderson type | (Orphanet:2769) |
Fibrochondrogenesis | (Orphanet:2021) |
Fine-Lubinsky syndrome | (Orphanet:1272) |
Flat face - microstomia - ear anomaly | (Orphanet:1968) |
Freeman-Sheldon syndrome | (Orphanet:2053) |
Fronto-facio-nasal dysostosis | (Orphanet:1791) |
Geroderma osteodysplastica | (Orphanet:2078) |
Glycogen storage disease due to glycogen debranching enzyme deficiency | (Orphanet:366) |
Goldenhar syndrome | (Orphanet:374) |
Gorlin-Chaudhry-Moss syndrome | (Orphanet:2095) |
Greenberg dysplasia | (Orphanet:1426) |
Gómez-López-Hernández syndrome | (Orphanet:1532) |
HOLOPROSENCEPHALY 2 | (OMIM:157170) |
HOLOPROSENCEPHALY 9 | (OMIM:610829) |
HUNTER-MACDONALD SYNDROME | (OMIM:611962) |
Hallermann-Streiff syndrome | (Orphanet:2108) |
Hennekam syndrome | (Orphanet:2136) |
Holoprosencephaly | (Orphanet:2162) |
Hutchinson-Gilford progeria syndrome | (Orphanet:740) |
Hydrocephalus - blue sclerae - nephropathy | (Orphanet:2186) |
Hydrocephalus - costovertebral dysplasia - Sprengel anomaly | (Orphanet:2180) |
Hyperphosphatasia-intellectual deficiency syndrome | (Orphanet:247262) |
Hypochondroplasia | (Orphanet:429) |
Hypomandibular faciocranial dysostosis | (Orphanet:1790) |
Hypospadias - hypertelorism - coloboma and deafness | (Orphanet:157788) |
ICF syndrome | (Orphanet:2268) |
Intellectual deficit - cataracts - calcified pinnae - myopathy | (Orphanet:3042) |
Intellectual deficit - short stature - hypertelorism | (Orphanet:3074) |
Intellectual deficit, X-linked - cubitus valgus - dysmorphism | (Orphanet:85280) |
Intellectual deficit, X-linked, Armfield type | (Orphanet:85276) |
Intellectual deficit, X-linked, Nascimento type | (Orphanet:163956) |
Jackson-Weiss syndrome | (Orphanet:1540) |
Joubert syndrome 14 | (OMIM:614424) |
Keutel syndrome | (Orphanet:85202) |
Kleefstra syndrome | (Orphanet:261494) |
Kniest dysplasia | (Orphanet:485) |
LOEYS-DIETZ SYNDROME 1 | (OMIM:609192) |
LOEYS-DIETZ SYNDROME 2 | (OMIM:610168) |
LUBS X-LINKED MENTAL RETARDATION SYNDROME | (OMIM:300260) |
Lambert syndrome | (Orphanet:1296) |
Larsen-like osseous dysplasia - short stature | (Orphanet:2370) |
Lateral meningocele syndrome | (Orphanet:2789) |
Lethal Kniest-like dysplasia | (Orphanet:2347) |
Lethal osteosclerotic bone dysplasia | (Orphanet:1832) |
Leukoencephalopathy - metaphyseal chondrodysplasia | (Orphanet:83629) |
Loeys-Dietz syndrome type 1 | (Orphanet:60030) |
MANDIBULOFACIAL DYSOSTOSIS WITH MENTAL DEFICIENCY | (OMIM:248400) |
MANDIBULOFACIAL DYSOSTOSIS WITH PTOSIS, AUTOSOMAL DOMINANT | (OMIM:608257) |
MENTAL RETARDATION, AUTOSOMAL RECESSIVE 15 | (OMIM:614202) |
MENTAL RETARDATION, AUTOSOMAL RECESSIVE 35 | (OMIM:615162) |
MIDFACE HYPOPLASIA, OBESITY, DEVELOPMENTAL DELAY, AND NEONATAL HYPOTONIA | (OMIM:608624) |
MUSCULAR DYSTROPHY-DYSTROGLYCANOPATHY (CONGENITAL WITH BRAIN AND EYEANOMALIES), TYPE A, 3 | (OMIM:253280) |
MYELODYSPLASIA, IMMUNODEFICIENCY, FACIAL DYSMORPHISM, SHORT STATURE,AND PSYCHOMOTOR DELAY | (OMIM:601347) |
Mandibulofacial dysostosis-microcephaly syndrome | (Orphanet:79113) |
Marden-Walker syndrome | (Orphanet:2461) |
Marfan syndrome | (Orphanet:558) |
Marfan syndrome type 1 | (Orphanet:284963) |
Marfanoid habitus - intellectual deficit, autosomal recessive | (Orphanet:2463) |
Marshall syndrome | (Orphanet:560) |
Marshall-Smith syndrome | (Orphanet:561) |
Mesomelia-synostoses syndrome | (Orphanet:2496) |
Metaphyseal acroscyphodysplasia | (Orphanet:1240) |
Microbrachycephaly - ptosis - cleft lip | (Orphanet:2511) |
Microcephalic osteodysplastic dysplasia, Saul-Wilson type | (Orphanet:85172) |
Microcephalic osteodysplastic primordial dwarfism types 1 and 3 | (Orphanet:2636) |
Microcephalic primordial dwarfism, Alazami type | (Orphanet:319671) |
Microcephaly - brachydactyly - kyphoscoliosis | (Orphanet:3433) |
Microcephaly - cervical spine fusion anomalies | (Orphanet:2522) |
Microphthalmia with brain and digit anomalies | (Orphanet:139471) |
Monosomy 18q | (Orphanet:1600) |
Monosomy 22q13 | (Orphanet:48652) |
Monosomy 9p | (Orphanet:261112) |
Mosaic variegated aneuploidy syndrome | (Orphanet:1052) |
Muenke syndrome | (Orphanet:53271) |
Mullerian derivatives - lymphangiectasia - polydactyly | (Orphanet:1655) |
Multiple congenital anomalies-hypotonia-seizures syndrome type 2 | (Orphanet:300496) |
Multiple epiphyseal dysplasia, Al-Gazali type | (Orphanet:166024) |
Myhre syndrome | (Orphanet:2588) |
Nager syndrome | (Orphanet:245) |
Nephrogenic diabetes insipidus - intracranial calcification | (Orphanet:3145) |
Nestor-Guillermo progeria syndrome | (Orphanet:280576) |
Night blindness - skeletal anomalies - dysmorphism | (Orphanet:1390) |
Non-eruption of teeth - maxillary hypoplasia - genu valgum | (Orphanet:2972) |
Non-rhizomelic chondrodysplasia punctata | (Orphanet:176) |
Norrie disease | (Orphanet:649) |
OSTEOGENESIS IMPERFECTA, TYPE X | (OMIM:613848) |
OSTEOGENESIS IMPERFECTA, TYPE XII | (OMIM:613849) |
OTOFACIOOSSEOUS-GONADAL SYNDROME | (OMIM:601976) |
Oculo-reno-cerebellar syndrome | (Orphanet:2715) |
Orofaciodigital syndrome type 1 | (Orphanet:2750) |
Orofaciodigital syndrome type 2 | (Orphanet:2751) |
Osteoglophonic dwarfism | (Orphanet:2645) |
Otopalatodigital syndrome | (Orphanet:669) |
Otopalatodigital syndrome type 1 | (Orphanet:90650) |
Otospondylomegaepiphyseal dysplasia | (Orphanet:1427) |
PECTUS EXCAVATUM, MACROCEPHALY, SHORT STATURE, AND DYSPLASTIC NAILS | (OMIM:600399) |
PEROXISOME BIOGENESIS DISORDER 3B | (OMIM:266510) |
PITUITARY HORMONE DEFICIENCY, COMBINED, 1 | (OMIM:613038) |
PLANTAR LIPOMATOSIS, UNUSUAL FACIES, AND DEVELOPMENTAL DELAY | (OMIM:602342) |
Paraplegia - brachydactyly - cone-shaped epiphysis | (Orphanet:2823) |
Patterson-Stevenson-Fontaine syndrome | (Orphanet:2439) |
Pectus excavatum - macrocephaly - dysplastic nails | (Orphanet:2835) |
Pfeiffer syndrome | (Orphanet:710) |
Phocomelia - ectrodactyly - deafness - sinus arrhythmia | (Orphanet:2878) |
Pierre Robin syndrome - faciodigital anomaly | (Orphanet:2888) |
Poikiloderma with neutropenia | (Orphanet:221046) |
Postaxial acrofacial dysostosis | (Orphanet:246) |
Prolidase deficiency | (Orphanet:742) |
Pseudodiastrophic dysplasia | (Orphanet:85174) |
RETINAL DYSTROPHY, JUVENILE CATARACTS, AND SHORT STATURE SYNDROME | (OMIM:616108) |
ROBERTS SYNDROME | (OMIM:268300) |
ROBINOW-SORAUF SYNDROME | (OMIM:180750) |
Recombinant 8 syndrome | (Orphanet:96167) |
Renpenning syndrome | (Orphanet:3242) |
Rhizomelic chondrodysplasia punctata | (Orphanet:177) |
Roberts syndrome | (Orphanet:3103) |
SHORT STATURE, AUDITORY CANAL ATRESIA, MANDIBULAR HYPOPLASIA, ANDSKELETAL ABNORMALITIES | (OMIM:602471) |
SHORT syndrome | (Orphanet:3163) |
SIMOSA CRANIOFACIAL SYNDROME | (OMIM:182150) |
SKELETAL DYSPLASIA AND PROGRESSIVE CENTRAL NERVOUS SYSTEM DEGENERATION,LETHAL | (OMIM:602613) |
SPONASTRIME dysplasia | (Orphanet:93357) |
STICKLER SYNDROME, TYPE I | (OMIM:108300) |
Saethre-Chotzen syndrome | (Orphanet:794) |
Sakati-Nyhan syndrome | (Orphanet:3128) |
Schilbach-Rott syndrome | (Orphanet:2353) |
Schinzel-Giedion syndrome | (Orphanet:798) |
Schneckenbecken dysplasia | (Orphanet:3144) |
Schwartz-Jampel syndrome | (Orphanet:800) |
Sclerosteosis | (Orphanet:3152) |
Short stature - craniofacial anomalies - genital hypoplasia | (Orphanet:2994) |
Smith-Magenis syndrome | (Orphanet:819) |
Spondyloepimetaphyseal dysplasia - short limb - abnormal calcification | (Orphanet:93358) |
Spondyloepimetaphyseal dysplasia with joint laxity | (Orphanet:93359) |
Spondyloepimetaphyseal dysplasia with multiple dislocations | (Orphanet:93360) |
Spondyloepimetaphyseal dysplasia, Bieganski type | (Orphanet:168448) |
Spondyloepimetaphyseal dysplasia, aggrecan type | (Orphanet:171866) |
Spondyloepiphyseal dysplasia congenita | (Orphanet:94068) |
Spondyloepiphyseal dysplasia tarda | (Orphanet:93284) |
Spondyloepiphyseal dysplasia, Cantu type | (Orphanet:163654) |
Spondyloperipheral dysplasia - short ulna | (Orphanet:1856) |
Stickler syndrome | (Orphanet:828) |
Stickler syndrome type 2 | (Orphanet:90654) |
Stickler syndrome type 3 | (Orphanet:166100) |
Stüve-Wiedemann syndrome | (Orphanet:3206) |
Subaortic stenosis - short stature | (Orphanet:3191) |
THREE M SYNDROME 2 | (OMIM:612921) |
THREE M SYNDROME 3 | (OMIM:614205) |
TMEM165-CDG | (Orphanet:314667) |
TREACHER COLLINS SYNDROME 1 | (OMIM:154500) |
TREACHER COLLINS SYNDROME 3 | (OMIM:248390) |
Terminal osseous dysplasia - pigmentary defects | (Orphanet:88630) |
Thrombocytopenia - absent radius | (Orphanet:3320) |
Toluene embryopathy | (Orphanet:1920) |
Treacher-Collins syndrome | (Orphanet:861) |
Tyrosinemia type 2 | (Orphanet:28378) |
Ulnar/fibula ray defect - brachydactyly | (Orphanet:52056) |
VAN MALDERGEM SYNDROME 1 | (OMIM:601390) |
VAN MALDERGEM SYNDROME 2 | (OMIM:615546) |
Van den Ende-Gupta syndrome | (Orphanet:2460) |
WHISTLING FACE SYNDROME, RECESSIVE FORM | (OMIM:277720) |
Wiedemann-Rautenstrauch syndrome | (Orphanet:3455) |
Williams syndrome | (Orphanet:904) |
X-linked creatine transporter deficiency | (Orphanet:52503) |
X-linked dominant chondrodysplasia punctata | (Orphanet:35173) |
X-linked intellectual deficit - hypotonic face | (Orphanet:73220) |
X-linked intellectual deficit with marfanoid habitus | (Orphanet:776) |
X-linked mandibulofacial dysostosis | (Orphanet:1131) |
Zechi-Ceide syndrome | (Orphanet:217017) |
Zellweger syndrome | (Orphanet:912) |
Zlotogora-Ogur syndrome | (Orphanet:3253) |
[DEL] NEUROFIBROMATOSIS-NOONAN SYNDROME | (OMIM:601321) |