Diarrhea

Symptom Information:

Symptom ID: HPO:0002014
Synonyms:
Diarrhea (finding) [Orphanet:27390]
Diarrhea symptom (finding) [Orphanet:27390]
Loose stool (finding) [Orphanet:27390]
Diarrhea [Orphanet:27390]
Diarrhea [OMIM:Diarrhea]
Acute diarrhea [Orphanet:27390]
Diarrhoea [Orphanet:27390]
Diarrhoea [MedDRA:10012735]
Acute diarrhea [MedDRA:10012735]
Antibiotic-associated diarrhea [MedDRA:10012735]
Diarrhea [MedDRA:10012735]
Diarrhea aggravated [MedDRA:10012735]
Diarrhea NOS [MedDRA:10012735]
Diarrhoea aggravated [MedDRA:10012735]
Diarrhoea functional (due to spastic colon) [MedDRA:10012735]
Diarrhoea NOS [MedDRA:10012735]
Explosive diarrhoea [MedDRA:10012735]
Frank diarrhoea [MedDRA:10012735]
Functional diarrhea [MedDRA:10012735]
Functional diarrhoea [MedDRA:10012735]
Functional diarrhoea (due to spastic colon) [MedDRA:10012735]
Iatrogenic diarrhea [MedDRA:10012735]
Iatrogenic diarrhoea [MedDRA:10012735]
Idiopathic diarrhea [MedDRA:10012735]
Loose bowel [MedDRA:10012735]
Loose bowels [MedDRA:10012735]
Loose motions [MedDRA:10012735]
Loose stools [MedDRA:10012735]
Mushy stool [MedDRA:10012735]
Nocturnal diarrhea [MedDRA:10012735]
Secretory diarrhea [MedDRA:10012735]
Stools loose [MedDRA:10012735]
Stools watery [MedDRA:10012735]
Urgent diarrhoea [MedDRA:10012735]
Watery diarrhoea [MedDRA:10012735]
Soft stools [MedDRA:10012735]
Diarrhea functional (due to spastic colon) [MedDRA:10012735]
Explosive diarrhea [MedDRA:10012735]
Frank diarrhea [MedDRA:10012735]
Functional diarrhea (due to spastic colon) [MedDRA:10012735]
Urgent diarrhea [MedDRA:10012735]
Watery diarrhea [MedDRA:10012735]
Acute diarrhoea [MedDRA:10012735]
Antibiotic-associated diarrhoea [MedDRA:10012735]
Idiopathic diarrhoea [MedDRA:10012735]
Nocturnal diarrhoea [MedDRA:10012735]
Secretory diarrhoea [MedDRA:10012735]
Mucous diarrhoea [MedDRA:10012735]
Mucous diarrhea [MedDRA:10012735]
Diarrhoea post chemotherapy [MedDRA:10012735]
Diarrhoea post irradiation [MedDRA:10012735]
Diarrhea post chemotherapy [MedDRA:10012735]
Diarrhea post irradiation [MedDRA:10012735]
Osmotic diarrhea [MedDRA:10012735]
Diarrhea recurrent [MedDRA:10012735]
Diarrhoea recurrent [MedDRA:10012735]
Chronic diarrhea [MedDRA:10012735]
Chronic diarrhoea [MedDRA:10012735]
Mushy diarrhoea [MedDRA:10012735]
Mushy diarrhea [MedDRA:10012735]
Paradoxical diarrhea [MedDRA:10012735]
Paradoxical diarrhoea [MedDRA:10012735]
Malodorous diarrhea [MedDRA:10012735]
Malodourous diarrhoea [MedDRA:10012735]
Osmotic diarrhoea [MedDRA:10012735]
Chronic diarrhea (in some patients) [OMIM:Chronic diarrhea (in some patients)]
Chronic diarrhea (seen in recessive form) [OMIM:Chronic diarrhea (seen in recessive form)]
Diarrhea (HCP) [OMIM:Diarrhea (HCP)]
Diarrhea (due to vasoactive intestinal peptide) [OMIM:Diarrhea (due to vasoactive intestinal peptide)]
Diarrhea (in 1 patient) [OMIM:Diarrhea (in 1 patient)]
Diarrhea (in severe cases) [OMIM:Diarrhea (in severe cases)]
Diarrhea (in some patients) [OMIM:Diarrhea (in some patients)]
Diarrhea, chronic [OMIM:Diarrhea, chronic]
Diarrhea, recurrent (1 patient) [OMIM:Diarrhea, recurrent (1 patient)]
Diarrhea, recurrent (less common) [OMIM:Diarrhea, recurrent (less common)]
Diarrhea, secretory [OMIM:Diarrhea, secretory]
Diarrhea, watery [OMIM:Diarrhea, watery]
Recurrent diarrhea (1 patient) [OMIM:Recurrent diarrhea (1 patient)]
Watery diarrhea (children and adults) [OMIM:Watery diarrhea (children and adults)]
Diarrhoea (excl infective) [MedDRA:10012736]
Quality:
Cross references:
Orphanet:27390 "Acute diarrhea" [Orphanet:27390]
OMIM: "Diarrhea" [OMIM:Diarrhea]
OMIM: "Chronic diarrhea (in some patients)" [OMIM:Chronic diarrhea (in some patients)]
OMIM: "Chronic diarrhea (seen in recessive form)" [OMIM:Chronic diarrhea (seen in recessive form)]
OMIM: "Diarrhea (HCP)" [OMIM:Diarrhea (HCP)]
OMIM: "Diarrhea (due to vasoactive intestinal peptide)" [OMIM:Diarrhea (due to vasoactive intestinal peptide)]
OMIM: "Diarrhea (in 1 patient)" [OMIM:Diarrhea (in 1 patient)]
OMIM: "Diarrhea (in severe cases)" [OMIM:Diarrhea (in severe cases)]
OMIM: "Diarrhea (in some patients)" [OMIM:Diarrhea (in some patients)]
OMIM: "Diarrhea, chronic" [OMIM:Diarrhea, chronic]
OMIM: "Diarrhea, recurrent (1 patient)" [OMIM:Diarrhea, recurrent (1 patient)]
OMIM: "Diarrhea, recurrent (less common)" [OMIM:Diarrhea, recurrent (less common)]
OMIM: "Diarrhea, secretory" [OMIM:Diarrhea, secretory]
OMIM: "Diarrhea, watery" [OMIM:Diarrhea, watery]
OMIM: "Recurrent diarrhea (1 patient)" [OMIM:Recurrent diarrhea (1 patient)]
OMIM: "Watery diarrhea (children and adults)" [OMIM:Watery diarrhea (children and adults)]
UMLS:C1963091 "Diarrhea" [HPO:0002014]
UMLS:C0011991 "Diarrhea" [Orphanet:27390]
Is a (Direct Parents):
HPO         Abdominal symptom
MedDRA Gastrointestinal motility and defaecation conditions
Orphanet Functional anomalies of the digestive system
Is a (Whole tree): HPO:
All(HPO:0000001)
    Phenotypic abnormality(HPO:0000118)
       Abnormality of the abdomen(HPO:0001438)
          Abdominal symptom(HPO:0011458)
             Diarrhea(HPO:0002014)
MedDRA:
Gastrointestinal disorders(MedDRA:10017947)
    Gastrointestinal motility and defaecation conditions(MedDRA:10017977)
       Diarrhea(HPO:0002014)
Database Frequency: 225 / 7739
Resource:

All diseases associated with this symptom:

5-oxoprolinase deficiency (Orphanet:33572)
AGAMMAGLOBULINEMIA 1, AUTOSOMAL RECESSIVE (OMIM:601495)
AGAMMAGLOBULINEMIA 3, AUTOSOMAL RECESSIVE (OMIM:613501)
AGAMMAGLOBULINEMIA 4, AUTOSOMAL RECESSIVE (OMIM:613502)
AGAMMAGLOBULINEMIA 6, AUTOSOMAL RECESSIVE (OMIM:612692)
AGAMMAGLOBULINEMIA, X-LINKED (OMIM:300755)
AL amyloidosis (Orphanet:85443)
ALG3-CDG (Orphanet:79321)
ATTRV122I amyloidosis (Orphanet:85451)
AUTOIMMUNE LYMPHOPROLIFERATIVE SYNDROME, TYPE V (OMIM:616100)
Acrodermatitis enteropathica, zinc deficiency type (Orphanet:37)
Acute intermittent porphyria (Orphanet:79276)
Adiposis dolorosa (Orphanet:36397)
Adult intestinal botulism (Orphanet:178487)
Aggressive systemic mastocytosis (Orphanet:98850)
Aromatic L-amino acid decarboxylase deficiency (Orphanet:35708)
Arthrogryposis - renal dysfunction - cholestasis (Orphanet:2697)
Aspartylglucosaminuria (Orphanet:93)
Atypical hemolytic uremic syndrome (Orphanet:2134)
Autoimmune lymphoproliferative syndrome with recurrent infections (Orphanet:275517)
Autoimmune polyendocrinopathy type 1 (Orphanet:3453)
Autosomal agammaglobulinemia (Orphanet:33110)
BARTTER SYNDROME, ANTENATAL, TYPE 1 (OMIM:601678)
BARTTER SYNDROME, ANTENATAL, TYPE 2 (OMIM:241200)
Barth syndrome (Orphanet:111)
Bartter syndrome (Orphanet:112)
Biotinidase deficiency (Orphanet:79241)
Bloom syndrome (Orphanet:125)
Bone dysplasia, lethal Holmgren type (Orphanet:1842)
Botulism (Orphanet:1267)
CELIAC DISEASE, SUSCEPTIBILITY TO, 1 (OMIM:212750)
COG4-CDG (Orphanet:263501)
CONGENITAL DISORDER OF GLYCOSYLATION, TYPE IIl (OMIM:614576)
Carney triad (Orphanet:139411)
Carnitine palmitoyl transferase 1A deficiency (Orphanet:156)
Central diabetes insipidus (Orphanet:178029)
Cerebrotendinous xanthomatosis (Orphanet:909)
Cholera (Orphanet:173)
Cholesteryl ester storage disease (Orphanet:75234)
Chronic diarrhea due to guanylate cyclase 2C overactivity (Orphanet:314373)
Chylomicron retention disease (Orphanet:71)
Classic galactosemia (Orphanet:79239)
Cogan syndrome (Orphanet:1467)
Cold agglutinin disease (Orphanet:56425)
Combined immunodeficiency due to ZAP70 deficiency (Orphanet:911)
Combined malonic and methylmalonic acidemia (Orphanet:289504)
Congenital bile acid synthesis defect type 1 (Orphanet:79301)
Congenital bile acid synthesis defect type 2 (Orphanet:79303)
Congenital bile acid synthesis defect type 3 (Orphanet:79302)
Congenital chloride diarrhea (Orphanet:53689)
Congenital enteropathy due to enteropeptidase deficiency (Orphanet:168601)
Congenital lactase deficiency (Orphanet:53690)
Congenital malabsorptive diarrhea due to paucity of enteroendocrine cells (Orphanet:83620)
Congenital sucrase-isomaltase deficiency (Orphanet:35122)
Congenital toxoplasmosis (Orphanet:858)
Crimean-Congo hemorrhagic fever (Orphanet:99827)
Cronkhite-Canada syndrome (Orphanet:2930)
Cushing syndrome due to ectopic ACTH secretion (Orphanet:99889)
Cutaneous mastocytosis (Orphanet:66646)
Cutaneous photosensitivity - lethal colitis (Orphanet:2881)
Cyclic neutropenia (Orphanet:2686)
Cystic fibrosis - gastritis - megaloblastic anemia (Orphanet:2575)
DIARRHEA 7 (OMIM:615863)
DYSKERATOSIS CONGENITA, AUTOSOMAL DOMINANT, 2 (OMIM:613989)
Dengue fever (Orphanet:99828)
Desminopathy (Orphanet:98909)
Diarrhea-vomiting due to trehalase deficiency (Orphanet:103909)
Distomatosis (Orphanet:1685)
Dracunculiasis (Orphanet:231)
ENTEROPATHY, FAMILIAL, WITH VILLOUS EDEMA AND IMMUNOGLOBULIN G2 DEFICIENCY (OMIM:600351)
ENTEROPATHY, PROTEIN-LOSING (OMIM:226300)
Ebola hemorrhagic fever (Orphanet:319218)
Eosinophilic granulomatosis with polyangiitis (Orphanet:183)
Fabry disease (Orphanet:324)
Familial Mediterranean fever (Orphanet:342)
Familial amyloid polyneuropathy (Orphanet:85447)
Familial dysautonomia (Orphanet:1764)
Familial visceral myopathy (Orphanet:2604)
Fanconi syndrome - ichthyosis - dysmorphism (Orphanet:1981)
Foodborne botulism (Orphanet:228371)
GRANULOMATOUS DISEASE, CHRONIC, AUTOSOMAL RECESSIVE, CYTOCHROME b-POSITIVE,TYPE III (OMIM:613960)
Gaucher disease type 1 (Orphanet:77259)
Gaucher disease type 2 (Orphanet:77260)
Gaucher disease type 3 (Orphanet:77261)
Generalized juvenile polyposis/juvenile polyposis coli (Orphanet:329971)
Generalized pseudohypoaldosteronism type 1 (Orphanet:171876)
Glutaric acidemia type 3 (Orphanet:35706)
Glycogen storage disease due to acid maltase deficiency, late-onset (Orphanet:420429)
Glycogen storage disease due to glucose-6-phosphatase deficiency type a (Orphanet:79258)
Glycogen storage disease due to glucose-6-phosphatase deficiency type b (Orphanet:79259)
Glycogen storage disease due to liver and muscle phosphorylase kinase deficiency (Orphanet:79240)
Glycogen storage disease due to phosphorylase kinase deficiency (Orphanet:370)
Good syndrome (Orphanet:169105)
HOMOZYGOUS 11p15-p14 DELETION SYNDROME (OMIM:606528)
HYPERPHOSPHATEMIA, POLYURIA, AND SEIZURES (OMIM:239350)
HYPERZINCEMIA WITH FUNCTIONAL ZINC DEPLETION (OMIM:601979)
Hawkinsinuria (Orphanet:2118)
Hemochromatosis type 4 (Orphanet:139491)
Hereditary angioedema type 1 (Orphanet:100050)
Hereditary angioedema type 2 (Orphanet:100051)
Hereditary coproporphyria (Orphanet:79273)
Hereditary folate malabsorption (Orphanet:90045)
Hereditary mucoepithelial dysplasia (Orphanet:1839)
Hirschsprung disease (Orphanet:388)
Hurler syndrome (Orphanet:93473)
Hurler-Scheie syndrome (Orphanet:93476)
Hyperammonemia due to N-acetylglutamate synthetase deficiency (Orphanet:927)
Hyperimmunoglobulinemia D with periodic fever (Orphanet:343)
Hyperinsulinism-hyperammonemia syndrome (Orphanet:35878)
Hyperornithinemia-hyperammonemia-homocitrullinuria (Orphanet:415)
Hypouricemia, renal, 2 (OMIM:612076)
ICF syndrome (Orphanet:2268)
IMMUNODEFICIENCY 19 (OMIM:615617)
IMMUNODEFICIENCY 22 (OMIM:615758)
IMMUNODEFICIENCY 31C (OMIM:614162)
IMMUNODEFICIENCY, COMMON VARIABLE, 1 (OMIM:607594)
IMMUNODEFICIENCY, COMMON VARIABLE, 2 (OMIM:240500)
IMMUNODEFICIENCY-CENTROMERIC INSTABILITY-FACIAL ANOMALIES SYNDROME1 (OMIM:242860)
INFLAMMATORY BOWEL DISEASE 1 (OMIM:266600)
INFLAMMATORY BOWEL DISEASE 11 (OMIM:191390)
Idiopathic giant cell myocarditis (Orphanet:329874)
Immune dysregulation-polyendocrinopathy-enteropathy-X-linked syndrome (Orphanet:37042)
Indolent systemic mastocytosis (Orphanet:98848)
Inhalational botulism (Orphanet:254504)
Insulin-resistance syndrome type A (Orphanet:2297)
Intestinal botulism (Orphanet:178481)
Isolated agammaglobulinemia (Orphanet:229717)
Jervell and Lange-Nielsen syndrome (Orphanet:90647)
Juvenile hyaline fibromatosis (Orphanet:2028)
Juvenile polyposis syndrome (Orphanet:2929)
Kawasaki disease (Orphanet:2331)
LACTOSE INTOLERANCE, ADULT TYPE (OMIM:223100)
LEUKOENCEPHALOPATHY, ARTHRITIS, COLITIS, AND HYPOGAMMAGLOBULINEMA (OMIM:608809)
Lassa fever (Orphanet:99824)
Legionellosis (Orphanet:549)
Lujo hemorrhagic fever (Orphanet:319213)
Lysinuric protein intolerance (Orphanet:470)
Lysosomal acid lipase deficiency (Orphanet:275761)
MEDNIK syndrome (Orphanet:171851)
MELAS (Orphanet:550)
METHIONINE MALABSORPTION SYNDROME (OMIM:250900)
MITCHELL-RILEY SYNDROME (OMIM:615710)
MPI-CDG (Orphanet:79319)
Maculopapular cutaneous mastocytosis (Orphanet:79457)
Malakoplakia (Orphanet:556)
Malonic aciduria (Orphanet:943)
Marburg hemorrhagic fever (Orphanet:99826)
Mastocytosis (Orphanet:98292)
Mevalonic aciduria (Orphanet:29)
Microscopic polyangiitis (Orphanet:727)
Mitochondrial DNA depletion syndrome, hepatocerebral form due to DGUOK deficiency (Orphanet:279934)
Mucopolysaccharidosis type 2 (Orphanet:580)
Mucopolysaccharidosis type 3 (Orphanet:581)
Multiple acyl-CoA dehydrogenase deficiency (Orphanet:26791)
Multiple endocrine neoplasia type 1 (Orphanet:652)
Multiple endocrine neoplasia type 2 (Orphanet:653)
Multiple endocrine neoplasia type 2B (Orphanet:247709)
NEUROBLASTOMA, SUSCEPTIBILITY TONEUROBLASTOMA, SUSCEPTIBILITY TO, 1, INCLUDED (OMIM:256700)
NEUROPATHY, HEREDITARY SENSORY AND AUTONOMIC, TYPE VII (OMIM:615548)
Navajo neurohepatopathy (Orphanet:255229)
Neonatal inflammatory skin and bowel disease (Orphanet:294023)
Neonatal intrahepatic cholestasis due to citrin deficiency (Orphanet:247598)
Neuroblastoma (Orphanet:635)
Nijmegen breakage syndrome (Orphanet:647)
Non-histaminic angioedema (Orphanet:658)
Obesity due to prohormone convertase I deficiency (Orphanet:71528)
Omenn syndrome (Orphanet:39041)
PAROXYSMAL NOCTURNAL HEMOGLOBINURIA 2 (OMIM:615399)
PMM2-CDG (Orphanet:79318)
Paroxysmal cold hemoglobinuria (Orphanet:90035)
Pediatric systemic sclerosis (Orphanet:93567)
Polyarteritis nodosa, childhood-onset (OMIM:615688)
Porphyria (Orphanet:738)
Primary erythermalgia (Orphanet:90026)
Primary systemic amyloidosis (Orphanet:314701)
Progressive external ophthalmoplegia - myopathy - emaciation (Orphanet:352447)
Progressive familial intrahepatic cholestasis (Orphanet:172)
Progressive familial intrahepatic cholestasis type 1 (Orphanet:79306)
Progressive familial intrahepatic cholestasis type 2 (Orphanet:79304)
Progressive familial intrahepatic cholestasis type 3 (Orphanet:79305)
Proximal tubulopathy - diabetes mellitus - cerebellar ataxia (Orphanet:3390)
Purine nucleoside phosphorylase deficiency (Orphanet:760)
RAPADILINO syndrome (Orphanet:3021)
Rabies (Orphanet:770)
Recurrent infections associated with rare immunoglobulin isotypes deficiency (Orphanet:183675)
Renal pseudohypoaldosteronism type 1 (Orphanet:171871)
Reticular dysgenesis (Orphanet:33355)
Retinal ischemic syndrome - digestive tract small vessel hyalinosis - diffuse cerebral calcifications (Orphanet:3018)
Rift valley fever (Orphanet:319251)
SATOYOSHI SYNDROME (OMIM:600705)
Sanfilippo syndrome type A (Orphanet:79269)
Sanfilippo syndrome type B (Orphanet:79270)
Sanfilippo syndrome type C (Orphanet:79271)
Sanfilippo syndrome type D (Orphanet:79272)
Scheie syndrome (Orphanet:93474)
Senile systemic amyloidosis (Orphanet:330001)
Severe combined immunodeficiency due to DCLRE1C deficiency (Orphanet:275)
Severe combined immunodeficiency due to adenosine deaminase deficiency (Orphanet:277)
Severe combined immunodeficiency due to complete RAG1/2 deficiency (Orphanet:331206)
Short chain acyl-CoA dehydrogenase deficiency (Orphanet:26792)
Short stature due to isolated growth hormone deficiency with X-linked hypogammaglobulinemia (Orphanet:632)
Sodium channelopathy-related small fiber neuropathy (Orphanet:306577)
Spontaneous periodic hypothermia (Orphanet:29822)
Syndromic diarrhea (Orphanet:84064)
Syndromic multisystem autoimmune disease due to Itch deficiency (Orphanet:228426)
Systemic capillary leak syndrome (Orphanet:188)
T-B+ severe combined immunodeficiency due to CD45 deficiency (Orphanet:169157)
T-B+ severe combined immunodeficiency due to IL-7Ralpha deficiency (Orphanet:169154)
T-B+ severe combined immunodeficiency due to JAK3 deficiency (Orphanet:35078)
TRAPS syndrome (Orphanet:32960)
TRICHOHEPATOENTERIC SYNDROME 2 (OMIM:614602)
Transcobalamin deficiency (Orphanet:859)
Transketolase deficiency (ORPHA:488618)
Typhoid (Orphanet:99745)
Very long chain acyl-CoA dehydrogenase deficiency (Orphanet:26793)
Viral hemorrhagic fever (Orphanet:341)
WISKOTT-ALDRICH SYNDROME (OMIM:301000)
WISKOTT-ALDRICH SYNDROME, AUTOSOMAL DOMINANT FORM (OMIM:600903)
Wolfram syndrome 1 (OMIM:222300)
Wolman disease (Orphanet:75233)
X-linked agammaglobulinemia (Orphanet:47)
X-linked hyper-IgM syndrome (Orphanet:101088)
X-linked lissencephaly with abnormal genitalia (Orphanet:452)
Yellow fever (Orphanet:99829)
[DEL] GLYCOGEN STORAGE DISEASE Ib (OMIM:232220)