Legionellosis

General Information (adopted from Orphanet):

Synonyms, Signs: Legionnaires&#39
disease
Number of Symptoms 41
OrphanetNr: 549
OMIM Id:
ICD-10: A48.1
UMLs: C0023240
C0023241
MeSH: D007876
D007877
MedDRA: 10035718
10061266
Snomed: 195889001
26726000
269574000
312403005

Prevalence, inheritance and age of onset:

Prevalence: 1.5 of 100 000 [Orphanet]
Inheritance: Not applicable
[Orphanet]
Age of onset: All ages
[Orphanet]

Disease classification (adopted from Orphanet):

Parent Diseases: Rare bacterial infectious disease
 -Rare infectious disease

Symptom Information: Sort by abundance 

1
 (HPO:0000093) Proteinuria Occasional [Orphanet] 169 / 7739
2
 (HPO:0000790) Hematuria Occasional [Orphanet] 106 / 7739
3
 (HPO:0000083) Renal insufficiency Occasional [Orphanet] 232 / 7739
4
 (HPO:0100776) Recurrent pharyngitis Occasional [Orphanet] 18 / 7739
5
 (HPO:0002383) Encephalitis Occasional [Orphanet] 41 / 7739
6
 (HPO:0000738) Hallucinations Occasional [Orphanet] 60 / 7739
7
 (HPO:0002066) Gait ataxia Occasional [Orphanet] 327 / 7739
8
 (HPO:0002315) Headache Occasional [Orphanet] 175 / 7739
9
 (HPO:0004372) Reduced consciousness/confusion Occasional [Orphanet] 73 / 7739
10
 (HPO:0009830) Peripheral neuropathy Occasional [Orphanet] 206 / 7739
11
 (HPO:0005059) Arthralgia/arthritis Occasional [Orphanet] 141 / 7739
12
 (HPO:0100749) Chest pain Frequent [Orphanet] 92 / 7739
13
 (HPO:0001396) Cholestasis Occasional [Orphanet] 136 / 7739
14
 (HPO:0002014) Diarrhea Occasional [Orphanet] 225 / 7739
15
 (HPO:0002039) Anorexia Occasional [Orphanet] 62 / 7739
16
 (HPO:0001733) Pancreatitis Occasional [Orphanet] 46 / 7739
17
 (HPO:0002027) Abdominal pain Occasional [Orphanet] 184 / 7739
18
 (HPO:0002017) Nausea and vomiting Occasional [Orphanet] 134 / 7739
19
 (HPO:0001744) Splenomegaly Occasional [Orphanet] 337 / 7739
20
 (HPO:0004306) Abnormality of the endocardium Occasional [Orphanet] 24 / 7739
21
 (HPO:0002615) Hypotension Occasional [Orphanet] 52 / 7739
22
 (HPO:0011675) Arrhythmia Frequent [Orphanet] 226 / 7739
23
 (HPO:0001697) Abnormality of the pericardium Occasional [Orphanet] 52 / 7739
24
 (HPO:0001637) Abnormality of the myocardium Occasional [Orphanet] 76 / 7739
25
 (HPO:0001876) Pancytopenia Occasional [Orphanet] 89 / 7739
26
 (HPO:0001888) Lymphopenia Occasional [Orphanet] 43 / 7739
27
 (HPO:0001945) Fever Very frequent [Orphanet] 218 / 7739
28
 (HPO:0002902) Hyponatremia Occasional [Orphanet] 37 / 7739
29
 (HPO:0002093) Respiratory insufficiency Frequent [Orphanet] 410 / 7739
30
 (HPO:0002113) Pulmonary infiltrates Very frequent [Orphanet] 36 / 7739
31
 (HPO:0002088) Abnormality of lung morphology Very frequent [Orphanet] 11 / 7739
32
 (HPO:0002105) Hemoptysis Occasional [Orphanet] 30 / 7739
33
 (HPO:0002091) Restrictive ventilatory defect Occasional [Orphanet] 46 / 7739
34
 (HPO:0002103) Abnormality of the pleura Occasional [Orphanet] 58 / 7739
35
 (HPO:0100806) Sepsis Occasional [Orphanet] 48 / 7739
36
 (HPO:0002716) Lymphadenopathy Occasional [Orphanet] 129 / 7739
37
 (HPO:0003326) Myalgia Very frequent [Orphanet] 143 / 7739
38
 (HPO:0001324) Muscle weakness Occasional [Orphanet] 859 / 7739
39
 (HPO:0003549) Abnormality of connective tissue Occasional [Orphanet] 22 / 7739
40
 (HPO:0001522) Death in infancy Occasional [Orphanet] 275 / 7739
41
 ([DEL]MedDRA:10011224) Cough Very frequent [Orphanet] 70 / 7739

Associated genes:

ClinVar (via SNiPA)

Gene symbol Variation Clinical significance Reference

Additional Information: