Pancytopenia

Symptom Information:

Symptom ID: HPO:0001876
Synonyms:
Bone marrow failure [Orphanet:48060]
Pancytopenia (disorder) [Orphanet:48060]
Pancytopenia [Orphanet:48060]
Pancytopenia [OMIM:Pancytopenia]
Bone marrow failure/pancytopenia [Orphanet:48060]
Pancytopenia [MedDRA:10033661]
Secondary pancytopenia [MedDRA:10033661]
Pancytopenia aggravated [MedDRA:10033661]
Hypocytosis [MedDRA:10033661]
Hematocytopenia [MedDRA:10033661]
Haematocytopenia [MedDRA:10033661]
Cytopenia [MedDRA:10033661]
Bone marrow failure [MedDRA:10065553]
Aplasia bone marrow [MedDRA:10065553]
Aplastic marrow [MedDRA:10065553]
Bone marrow aplastic [MedDRA:10065553]
Bone marrow depression [MedDRA:10065553]
Bone marrow depression NOS [MedDRA:10065553]
Depression bone marrow (NOS) [MedDRA:10065553]
Haematopoiesis decreased [MedDRA:10065553]
Haematopoiesis impaired [MedDRA:10065553]
Haematopoiesis suppressed [MedDRA:10065553]
Haemopoiesis decreased [MedDRA:10065553]
Haemopoiesis impaired [MedDRA:10065553]
Haemopoiesis suppressed [MedDRA:10065553]
Hematopoiesis depressed [MedDRA:10065553]
Hematopoiesis impaired [MedDRA:10065553]
Hematopoiesis suppressed [MedDRA:10065553]
Hypocellular marrow [MedDRA:10065553]
Hypoplasia bone marrow [MedDRA:10065553]
Hypoplasia erythroid [MedDRA:10065553]
Hypoplastic marrow [MedDRA:10065553]
Marrow depression [MedDRA:10065553]
Marrow depression of [MedDRA:10065553]
Marrow hypoplasia [MedDRA:10065553]
Myelosuppression [MedDRA:10065553]
Myelosuppression adult [MedDRA:10065553]
Panmyelophthisis [MedDRA:10065553]
Bone marrow hypocellular [MedDRA:10065553]
Haematopoiesis depressed [MedDRA:10065553]
Hematopoiesis decreased [MedDRA:10065553]
Hemopoiesis decreased [MedDRA:10065553]
Hemopoiesis impaired [MedDRA:10065553]
Hemopoiesis suppressed [MedDRA:10065553]
Bone marrow aplasia [OMIM:Bone marrow aplasia]
Bone marrow failure (1 patient) [OMIM:Bone marrow failure (1 patient)]
Bone marrow failure (classic feature, NOLA3 patient) [OMIM:Bone marrow failure (classic feature, NOLA3 patient)]
Bone marrow failure (in some patients) [OMIM:Bone marrow failure (in some patients)]
Bone marrow hypoplasia (in some patients) [OMIM:Bone marrow hypoplasia (in some patients)]
Hypocellular bone marrow [OMIM:Hypocellular bone marrow]
Pancytopenia (4 patients) [OMIM:Pancytopenia (4 patients)]
Pancytopenia (childhood) [OMIM:Pancytopenia (childhood)]
Pancytopenia (in 2 of 3 siblings) [OMIM:Pancytopenia (in 2 of 3 siblings)]
Pancytopenia (in 50% of patients) [OMIM:Pancytopenia (in 50% of patients)]
Pancytopenia (in some patients) [OMIM:Pancytopenia (in some patients)]
Quality:
Cross references:
HPO:0100549 "Bone marrow failure" [Orphanet:48060]
Orphanet:48060 "Bone marrow failure/pancytopenia" [Orphanet:48060]
OMIM: "Pancytopenia" [OMIM:Pancytopenia]
OMIM: "Bone marrow aplasia" [OMIM:Bone marrow aplasia]
OMIM: "Bone marrow failure (1 patient)" [OMIM:Bone marrow failure (1 patient)]
OMIM: "Bone marrow failure (classic feature, NOLA3 patient)" [OMIM:Bone marrow failure (classic feature, NOLA3 patient)]
OMIM: "Bone marrow failure (in some patients)" [OMIM:Bone marrow failure (in some patients)]
OMIM: "Bone marrow hypoplasia (in some patients)" [OMIM:Bone marrow hypoplasia (in some patients)]
OMIM: "Hypocellular bone marrow" [OMIM:Hypocellular bone marrow]
OMIM: "Pancytopenia (4 patients)" [OMIM:Pancytopenia (4 patients)]
OMIM: "Pancytopenia (childhood)" [OMIM:Pancytopenia (childhood)]
OMIM: "Pancytopenia (in 2 of 3 siblings)" [OMIM:Pancytopenia (in 2 of 3 siblings)]
OMIM: "Pancytopenia (in 50% of patients)" [OMIM:Pancytopenia (in 50% of patients)]
OMIM: "Pancytopenia (in some patients)" [OMIM:Pancytopenia (in some patients)]
UMLS:C0030312 "Pancytopenia" [HPO:0001876]
UMLS:C0030312 "Pancytopenia" [Orphanet:48060]
Is a (Direct Parents):
HPO         Abnormality of multiple cell lineages in the bone marrow
Orphanet Abnormality of bone marrow cell morphology
MedDRA Marrow depression and hypoplastic anaemias
Is a (Whole tree): HPO:
All(HPO:0000001)
    Phenotypic abnormality(HPO:0000118)
       Abnormality of blood and blood-forming tissues(HPO:0001871)
          Abnormality of bone marrow cell morphology(HPO:0005561)
             Abnormality of multiple cell lineages in the bone marrow(HPO:0012145)
                Pancytopenia(HPO:0001876)
MedDRA:
Blood and lymphatic system disorders(MedDRA:10005329)
    Anaemias nonhaemolytic and marrow depression(MedDRA:10002086)
       Marrow depression and hypoplastic anaemias(MedDRA:10026847)
          Pancytopenia(HPO:0001876)
Database Frequency: 89 / 7739
Resource:

All diseases associated with this symptom:

AICARDI-GOUTIERES SYNDROME 4 (OMIM:610333)
AUTOINFLAMMATION WITH INFANTILE ENTEROCOLITIS (OMIM:616050)
Adult Still's disease (Orphanet:829)
Aggressive systemic mastocytosis (Orphanet:98850)
Albers-Schönberg osteopetrosis (Orphanet:53)
Ataxia - pancytopenia (Orphanet:2585)
Autosomal dominant aplasia and myelodysplasia (Orphanet:314399)
Autosomal recessive lymphoproliferative disease (Orphanet:238505)
Autosomal recessive malignant osteopetrosis (Orphanet:667)
Bangstad syndrome (Orphanet:1227)
Beta-thalassemia major (Orphanet:231214)
COENZYME Q10 DEFICIENCY, PRIMARY, 1 (OMIM:607426)
Coats plus syndrome (Orphanet:313838)
Congenital amegakaryocytic thrombocytopenia (Orphanet:3319)
Constitutional megaloblastic anemia with severe neurologic disease (Orphanet:319651)
Cranioectodermal dysplasia 4 (OMIM:614378)
DYSKERATOSIS CONGENITA, AUTOSOMAL DOMINANT, 1 (OMIM:127550)
DYSKERATOSIS CONGENITA, AUTOSOMAL DOMINANT, 2 (OMIM:613989)
DYSKERATOSIS CONGENITA, AUTOSOMAL DOMINANT, 3 (OMIM:613990)
DYSKERATOSIS CONGENITA, AUTOSOMAL RECESSIVE, 1 (OMIM:224230)
DYSKERATOSIS CONGENITA, AUTOSOMAL RECESSIVE, 2 (OMIM:613987)
DYSKERATOSIS CONGENITA, AUTOSOMAL RECESSIVE, 3 (OMIM:613988)
Deafness - intellectual deficit, Martin-Probst type (Orphanet:85321)
Deafness - lymphedema - leukemia (Orphanet:3226)
Dyskeratosis congenita (Orphanet:1775)
ENCEPHALOMYOPATHY, MITOCHONDRIAL, DUE TO VOLTAGE-DEPENDENT ANION CHANNELDEFICIENCY (OMIM:614520)
FANCONI ANEMIA, COMPLEMENTATION GROUP A (OMIM:227650)
FANCONI ANEMIA, COMPLEMENTATION GROUP C (OMIM:227645)
FANCONI ANEMIA, COMPLEMENTATION GROUP D2 (OMIM:227646)
FANCONI ANEMIA, COMPLEMENTATION GROUP E (OMIM:600901)
FANCONI ANEMIA, COMPLEMENTATION GROUP P (OMIM:613951)
FANCONI-LIKE SYNDROME (OMIM:227850)
Fanconi anemia (Orphanet:84)
Felty syndrome (Orphanet:47612)
Gaucher disease (Orphanet:355)
Gaucher disease - ophthalmoplegia - cardiovascular calcification (Orphanet:2072)
Gaucher disease type 1 (Orphanet:77259)
Gaucher disease type 2 (Orphanet:77260)
Gaucher disease type 3 (Orphanet:77261)
Ghosal hematodiaphyseal dysplasia (Orphanet:1802)
Griscelli disease (Orphanet:381)
Griscelli disease type 2 (Orphanet:79477)
Hairy cell leukemia variant (Orphanet:300878)
Hashimoto-Pritzker syndrome (Orphanet:99872)
Hereditary folate malabsorption (Orphanet:90045)
Hodgkin lymphoma (Orphanet:98293)
Hodgkin lymphoma, classical (Orphanet:391)
Hoyeraal-Hreidarsson syndrome (Orphanet:3322)
Hyperuricemia-pulmonary hypertension-renal failure-alkalosis syndrome (Orphanet:363694)
IMMUNODEFICIENCY 16 (OMIM:615593)
IMMUNODEFICIENCY, COMMON VARIABLE, 8, WITH AUTOIMMUNITY (OMIM:614700)
INTRAUTERINE GROWTH RETARDATION WITH INCREASED MITOMYCIN C SENSITIVITY (OMIM:600546)
Isovaleric acidemia (Orphanet:33)
Jacobsen syndrome (Orphanet:2308)
LIG4 syndrome (Orphanet:99812)
LYMPHOID SYSTEM DETERIORATION, PROGRESSIVE (OMIM:247630)
LYMPHOPROLIFERATIVE SYNDROME 1 (OMIM:613011)
LYMPHOPROLIFERATIVE SYNDROME 2 (OMIM:615122)
LYMPHOPROLIFERATIVE SYNDROME, X-LINKED, 1 (OMIM:308240)
Legionellosis (Orphanet:549)
Methylmalonic acidemia with homocystinuria (Orphanet:26)
Methylmalonic acidemia with homocystinuria, type cblF (Orphanet:79284)
Nodular lymphocyte predominant Hodgkin lymphoma (Orphanet:86893)
OSTEOPETROSIS, AUTOSOMAL RECESSIVE 1 (OMIM:259700)
OSTEOPETROSIS, AUTOSOMAL RECESSIVE 2 (OMIM:259710)
Osteopetrosis (Orphanet:2781)
PANCYTOPENIA AND OCCLUSIVE VASCULAR DISEASE (OMIM:167850)
PULMONARY FIBROSIS AND/OR BONE MARROW FAILURE, TELOMERE-RELATED, 1 (OMIM:614742)
PULMONARY FIBROSIS AND/OR BONE MARROW FAILURE, TELOMERE-RELATED, 2 (OMIM:614743)
Pearson syndrome (Orphanet:699)
Propionic acidemia (Orphanet:35)
Pyogenic arthritis - pyoderma gangrenosum - acne (Orphanet:69126)
RAS-ASSOCIATED AUTOIMMUNE LEUKOPROLIFERATIVE DISORDER (OMIM:614470)
Radio-ulnar synostosis - amegakaryocytic thrombocytopenia (Orphanet:71289)
SECKEL SYNDROME 1 (OMIM:210600)
SPLENOMEGALY SYNDROME WITH SPLENIC GERMINAL CENTER HYPOPLASIA ANDREDUCED CIRCULATING T HELPER CELLS (OMIM:183350)
SPLENOMEGALY, CYTOPENIA, AND VISION LOSS (OMIM:614979)
Sarcoidosis (Orphanet:797)
Seckel syndrome (Orphanet:808)
Shwachman-Diamond syndrome (Orphanet:811)
Systemic mastocytosis (Orphanet:2467)
Thymoma (Orphanet:99867)
Transaldolase deficiency (Orphanet:101028)
Transcobalamin deficiency (Orphanet:859)
Vitamin B12-responsive methylmalonic acidemia (Orphanet:28)
Vitamin B12-responsive methylmalonic acidemia type cblA (Orphanet:79310)
Vitamin B12-responsive methylmalonic acidemia type cblB (Orphanet:79311)
WT limb-blood syndrome (Orphanet:3466)
Wilson disease (Orphanet:905)