Adult Still's disease

General Information (adopted from Orphanet):

Synonyms, Signs: Wissler-Fanconi syndrome
Number of Symptoms 25
OrphanetNr: 829
OMIM Id:
ICD-10: M06.1
UMLs: C0043195
C0085253
MeSH: D014924
D016706
MedDRA: 10058493
10064056
Snomed: 239920006
68190001

Prevalence, inheritance and age of onset:

Prevalence: 1.25 [Orphanet]
Inheritance:
[Orphanet]
Age of onset: Adult
[Orphanet]

Disease classification (adopted from Orphanet):

Parent Diseases: Rare rheumatologic disease
 -Rare systemic or rheumatologic disease
Secondary glomerular disease
 -Rare renal disease

Symptom Information: Sort by abundance 

1
 (HPO:0100776) Recurrent pharyngitis Occasional [Orphanet] 18 / 7739
2
 (HPO:0001287) Meningitis Occasional [Orphanet] 46 / 7739
3
 (HPO:0005059) Arthralgia/arthritis Very frequent [Orphanet] 141 / 7739
4
 (HPO:0100769) Synovitis Very frequent [Orphanet] 86 / 7739
5
 (HPO:0100773) Cartilage destruction Occasional [Orphanet] 7 / 7739
6
 (HPO:0001396) Cholestasis Occasional [Orphanet] 136 / 7739
7
 (HPO:0002910) Elevated hepatic transaminases Occasional [Orphanet] 158 / 7739
8
 (HPO:0001744) Splenomegaly Very frequent [Orphanet] 337 / 7739
9
 (HPO:0002027) Abdominal pain Frequent [Orphanet] 184 / 7739
10
 (HPO:0002240) Hepatomegaly Very frequent [Orphanet] 467 / 7739
11
 (HPO:0000989) Pruritus Very frequent [Orphanet] 111 / 7739
12
 (HPO:0000988) Skin rash Very frequent [Orphanet] 98 / 7739
13
 (HPO:0001025) Urticaria Very frequent [Orphanet] 73 / 7739
14
 (HPO:0001637) Abnormality of the myocardium Occasional [Orphanet] 76 / 7739
15
 (HPO:0001697) Abnormality of the pericardium Frequent [Orphanet] 52 / 7739
16
 (HPO:0001974) Leukocytosis Very frequent [Orphanet] 33 / 7739
17
 (HPO:0001876) Pancytopenia Occasional [Orphanet] 89 / 7739
18
 (HPO:0003119) Abnormality of lipid metabolism Occasional [Orphanet] 60 / 7739
19
 (HPO:0011227) Elevated C-reactive protein level Very frequent [Orphanet] 55 / 7739
20
 (HPO:0001945) Fever Very frequent [Orphanet] 218 / 7739
21
 (HPO:0002091) Restrictive ventilatory defect Very frequent [Orphanet] 46 / 7739
22
 (HPO:0002103) Abnormality of the pleura Frequent [Orphanet] 58 / 7739
23
 (HPO:0100721) Mediastinal lymphadenopathy Frequent [Orphanet] 19 / 7739
24
 (HPO:0001324) Muscle weakness Very frequent [Orphanet] 859 / 7739
25
 (HPO:0003326) Myalgia Frequent [Orphanet] 143 / 7739

Associated genes:

ClinVar (via SNiPA)

Gene symbol Variation Clinical significance Reference

Additional Information: