Elevated hepatic transaminases

Symptom Information:

Symptom ID: HPO:0002910
Synonyms:
Abnormal liver enzymes [HPO:0002910]
Abnormal liver function [HPO:0002910]
Abnormal liver function tests [HPO:0002910]
Elevated liver enzymes [HPO:0002910]
Elevated liver function tests [HPO:0002910]
Elevated serum transaminases [HPO:0002910]
Elevated transaminases [HPO:0002910]
Increased liver enzymes [HPO:0002910]
Increased liver function tests [HPO:0002910]
Increased transaminases [HPO:0002910]
Subclinical abnormal liver function tests [HPO:0002910]
Abnormal liver enzymes [OMIM:Abnormal liver enzymes]
Abnormal liver function [OMIM:Abnormal liver function]
Abnormal liver function tests [OMIM:Abnormal liver function tests]
Elevated hepatic transaminases [OMIM:Elevated hepatic transaminases]
Elevated liver enzymes [OMIM:Elevated liver enzymes]
Elevated liver function tests [OMIM:Elevated liver function tests]
Elevated serum transaminases [OMIM:Elevated serum transaminases]
Elevated transaminases [OMIM:Elevated transaminases]
Increased liver enzymes [OMIM:Increased liver enzymes]
Increased liver function tests [OMIM:Increased liver function tests]
Increased transaminases [OMIM:Increased transaminases]
Subclinical abnormal liver function tests [OMIM:Subclinical abnormal liver function tests]
Abnormal liver enzymes (1 patient) [OMIM:Abnormal liver enzymes (1 patient)]
Abnormal liver enzymes (in 1 patient) [OMIM:Abnormal liver enzymes (in 1 patient)]
Abnormal liver enzymes (in some patients) [OMIM:Abnormal liver enzymes (in some patients)]
Abnormal liver enzymes (rare) [OMIM:Abnormal liver enzymes (rare)]
Abnormal liver function (26%) [OMIM:Abnormal liver function (26%)]
Abnormal liver function (in some patients) [OMIM:Abnormal liver function (in some patients)]
Abnormal liver function tests (SGOT, SGPT) [OMIM:Abnormal liver function tests (SGOT, SGPT)]
Abnormal liver function tests (in some patients) [OMIM:Abnormal liver function tests (in some patients)]
Abnormal liver function tests (less common) [OMIM:Abnormal liver function tests (less common)]
Elevated liver enzymes (in some patients) [OMIM:Elevated liver enzymes (in some patients)]
Liver function test abnormal [MedDRA:10024690]
Transaminases increased [MedDRA:10054889]
Quality:
Cross references:
OMIM: "Abnormal liver enzymes" [OMIM:Abnormal liver enzymes]
OMIM: "Abnormal liver function" [OMIM:Abnormal liver function]
OMIM: "Abnormal liver function tests" [OMIM:Abnormal liver function tests]
OMIM: "Elevated hepatic transaminases" [OMIM:Elevated hepatic transaminases]
OMIM: "Elevated liver enzymes" [OMIM:Elevated liver enzymes]
OMIM: "Elevated liver function tests" [OMIM:Elevated liver function tests]
OMIM: "Elevated serum transaminases" [OMIM:Elevated serum transaminases]
OMIM: "Elevated transaminases" [OMIM:Elevated transaminases]
OMIM: "Increased liver enzymes" [OMIM:Increased liver enzymes]
OMIM: "Increased liver function tests" [OMIM:Increased liver function tests]
OMIM: "Increased transaminases" [OMIM:Increased transaminases]
OMIM: "Subclinical abnormal liver function tests" [OMIM:Subclinical abnormal liver function tests]
OMIM: "Abnormal liver enzymes (1 patient)" [OMIM:Abnormal liver enzymes (1 patient)]
OMIM: "Abnormal liver enzymes (in 1 patient)" [OMIM:Abnormal liver enzymes (in 1 patient)]
OMIM: "Abnormal liver enzymes (in some patients)" [OMIM:Abnormal liver enzymes (in some patients)]
OMIM: "Abnormal liver enzymes (rare)" [OMIM:Abnormal liver enzymes (rare)]
OMIM: "Abnormal liver function (26%)" [OMIM:Abnormal liver function (26%)]
OMIM: "Abnormal liver function (in some patients)" [OMIM:Abnormal liver function (in some patients)]
OMIM: "Abnormal liver function tests (SGOT, SGPT)" [OMIM:Abnormal liver function tests (SGOT, SGPT)]
OMIM: "Abnormal liver function tests (in some patients)" [OMIM:Abnormal liver function tests (in some patients)]
OMIM: "Abnormal liver function tests (less common)" [OMIM:Abnormal liver function tests (less common)]
OMIM: "Elevated liver enzymes (in some patients)" [OMIM:Elevated liver enzymes (in some patients)]
Is a (Direct Parents):
HPO         Abnormality of the liver
MedDRA Liver function analyses
Is a (Whole tree): HPO:
All(HPO:0000001)
    Phenotypic abnormality(HPO:0000118)
       Abnormality of the abdomen(HPO:0001438)
          Abnormality of the abdominal organs(HPO:0002012)
             Abnormality of the liver(HPO:0001392)
                Elevated hepatic transaminases(HPO:0002910)
MedDRA:
Investigations(MedDRA:10022891)
    Hepatobiliary investigations(MedDRA:10019809)
       Liver function analyses(MedDRA:10024689)
          Elevated hepatic transaminases(HPO:0002910)
Database Frequency: 158 / 7739
Resource:

All diseases associated with this symptom:

17q12 microdeletion syndrome (Orphanet:261265)
AICARDI-GOUTIERES SYNDROME 1 (OMIM:225750)
AICARDI-GOUTIERES SYNDROME 3 (OMIM:610329)
AICARDI-GOUTIERES SYNDROME 4 (OMIM:610333)
ARTHROGRYPOSIS, RENAL DYSFUNCTION, AND CHOLESTASIS 2 (OMIM:613404)
Acute infantile liver failure due to synthesis defect of mtDNA-encoded proteins (Orphanet:217371)
Acute infantile liver failure-multisystemic involvement syndrome (Orphanet:370088)
Acyl-CoA dehydrogenase 9 deficiency (Orphanet:99901)
Adult Still's disease (Orphanet:829)
Alagille syndrome due to 20p12 microdeletion (Orphanet:261600)
Alagille syndrome due to a JAG1 point mutation (Orphanet:261619)
Alpers syndrome (Orphanet:726)
Alpha-1-antitrypsin deficiency (Orphanet:60)
Alström syndrome (Orphanet:64)
Arthrogryposis - renal dysfunction - cholestasis (Orphanet:2697)
Ataxia-telangiectasia (Orphanet:100)
BILE ACID SYNTHESIS DEFECT, CONGENITAL, 4 (OMIM:214950)
BILE ACID SYNTHESIS DEFECT, CONGENITAL, 5 (OMIM:616278)
Bardet-Biedl syndrome 1 (OMIM:209900 )
Bardet-Biedl syndrome 10 (OMIM:615987)
Bardet-Biedl syndrome 12 (OMIM:615989)
Bardet-Biedl syndrome 4 (OMIM:615982)
Bardet-Biedl syndrome 6 (OMIM:605231)
Bardet-Biedl syndrome 7 (OMIM:615984)
Benign recurrent intrahepatic cholestasis (Orphanet:65682)
Beta-thalassemia major (Orphanet:231214)
Bifunctional enzyme deficiency (Orphanet:300)
Biliary atresia (Orphanet:30391)
Budd-Chiari syndrome (Orphanet:131)
CELIAC DISEASE, SUSCEPTIBILITY TO, 1 (OMIM:212750)
COG4-CDG (Orphanet:263501)
CONGENITAL DISORDER OF DEGLYCOSYLATION (OMIM:615273)
CONGENITAL DISORDER OF GLYCOSYLATION, TYPE IIl (OMIM:614576)
Carnitine palmitoyl transferase 1A deficiency (Orphanet:156)
Carnitine palmitoyl transferase II deficiency (Orphanet:157)
Carnitine palmitoyl transferase II deficiency, neonatal form (Orphanet:228308)
Carnitine palmitoyl transferase II deficiency, severe infantile form (Orphanet:228305)
Carnitine uptake deficiency (Orphanet:158)
Carnitine-acylcarnitine translocase deficiency (Orphanet:159)
Cerebroretinal vasculopathy (Orphanet:3421)
Cholestasis - lymphedema (Orphanet:1414)
Cholestasis - pigmentary retinopathy - cleft palate (Orphanet:1415)
Choreoacanthocytosis (Orphanet:2388)
Cirrhosis-dystonia-polycythemia-hypermanganesemia syndrome (Orphanet:309854)
Citrullinemia type II (Orphanet:247585)
Classical homocystinuria (Orphanet:394)
Combined oxidative phosphorylation defect type 2 (Orphanet:254920)
Combined oxidative phosphorylation defect type 9 (Orphanet:319509)
Common variable immunodeficiency (Orphanet:1572)
Congenital bile acid synthesis defect type 1 (Orphanet:79301)
Congenital bile acid synthesis defect type 2 (Orphanet:79303)
Congenital bile acid synthesis defect type 3 (Orphanet:79302)
Congenital bile acid synthesis defect type 4 (Orphanet:79095)
Congenital disorder of glycosylation (Orphanet:137)
Congenital intrauterine infection-like syndrome (Orphanet:1229)
Congenital toxoplasmosis (Orphanet:858)
Crimean-Congo hemorrhagic fever (Orphanet:99827)
DK1-CDG (Orphanet:91131)
DPAGT1-CDG (Orphanet:86309)
DPM1-CDG (Orphanet:79322)
DPM3-CDG (Orphanet:263494)
Disorder of bile acid synthesis (Orphanet:79168)
Drug rash with eosinophilia and systemic symptoms (Orphanet:139402)
Early-onset familial noncirrhotic portal hypertension (ORPHA:494348)
Fetal Gaucher disease (Orphanet:85212)
GLYCOGEN STORAGE DISEASE IXc (OMIM:613027)
Gaucher disease type 2 (Orphanet:77260)
Generalized congenital lipodystrophy with myopathy (Orphanet:228429)
Glycogen storage disease due to glucose-6-phosphatase deficiency (Orphanet:364)
Glycogen storage disease due to glucose-6-phosphatase deficiency type a (Orphanet:79258)
Glycogen storage disease due to glucose-6-phosphatase deficiency type b (Orphanet:79259)
Glycogen storage disease due to glycogen debranching enzyme deficiency (Orphanet:366)
Glycogen storage disease due to hepatic glycogen synthase deficiency (Orphanet:2089)
Glycogen storage disease due to liver phosphorylase kinase deficiency (Orphanet:264580)
HERNS syndrome (Orphanet:63261)
Hairy cell leukemia variant (Orphanet:300878)
Hashimoto-Pritzker syndrome (Orphanet:99872)
Hemochromatosis type 3 (Orphanet:225123)
Hemochromatosis type 4 (Orphanet:139491)
Hemochromatosis, type 1 (OMIM:235200)
Hemochromatosis, type 2A (OMIM:602390)
Hemochromatosis, type 2B (OMIM:613313)
Hemorrhagic fever - renal syndrome (Orphanet:340)
Hereditary fructose intolerance (Orphanet:469)
Hereditary vascular retinopathy (Orphanet:71291)
Hurler syndrome (Orphanet:93473)
Hypermethioninemia due to glycine N-methyltransferase deficiency (Orphanet:289891)
Hypermethioninemia encephalopathy due to adenosine kinase deficiency (Orphanet:289290)
Hyperornithinemia-hyperammonemia-homocitrullinuria (Orphanet:415)
INFANTILE LIVER FAILURE SYNDROME 2 (OMIM:615486)
INTERSTITIAL NEPHRITIS, KARYOMEGALIC (OMIM:614817)
Infantile hypertrophic cardiomyopathy due to MRPL44 deficiency (Orphanet:352563)
Infantile onset spinocerebellar ataxia (Orphanet:1186)
Infantile regressive hypertriglyceridemia and hepatosteatosis (Orphanet:300293)
Isolated CoQ-cytochrome C reductase deficiency (Orphanet:1460)
Joubert syndrome 1 (OMIM:213300)
Joubert syndrome 2 (OMIM:608091)
Joubert syndrome 21 (OMIM:615636)
Joubert syndrome with hepatic defect (Orphanet:1454)
LIPOYLTRANSFERASE 1 DEFICIENCY (OMIM:616299)
Lathosterolosis (Orphanet:46059)
Leigh syndrome (Orphanet:506)
Leukoencephalopathy - thalamus and brainstem anomalies - high lactate (Orphanet:314051)
Low phospholipid associated cholelithiasis (Orphanet:69663)
Lyell syndrome (Orphanet:537)
MITOCHONDRIAL COMPLEX III DEFICIENCY, NUCLEAR TYPE 6 (OMIM:615453)
Mandibular hypoplasia-deafness-progeroid syndrome (Orphanet:363649)
Marburg hemorrhagic fever (Orphanet:99826)
McCune-Albright syndrome (Orphanet:562)
McLeod neuroacanthocytosis syndrome (Orphanet:59306)
Medium chain acyl-CoA dehydrogenase deficiency (Orphanet:42)
Mevalonic aciduria (Orphanet:29)
Mitochondrial DNA depletion syndrome, encephalomyopathic form with variable craniofacial anomalies (Orphanet:369897)
Mitochondrial DNA depletion syndrome, hepatocerebral form due to DGUOK deficiency (Orphanet:279934)
Mitochondrial trifunctional protein deficiency (Orphanet:746)
Multiple acyl-CoA dehydrogenase deficiency (Orphanet:26791)
Myopathy, lactic acidosis, and sideroblastic anemia 2; MLASA2 (OMIM:613561)
NEPHROPATHY, PROGRESSIVE TUBULOINTERSTITIAL, WITH CHOLESTATIC LIVERDISEASE (OMIM:602114)
Nakajo-Nishimura syndrome (Orphanet:2615)
Navajo neurohepatopathy (Orphanet:255229)
Nephronophthisis 3 (OMIM:604387)
Neutral lipid storage myopathy (Orphanet:98908)
Orofaciodigital syndrome type 1 (Orphanet:2750)
PEROXISOME BIOGENESIS DISORDER 11A (ZELLWEGER) (OMIM:614883)
PEROXISOME BIOGENESIS DISORDER 12A (ZELLWEGER) (OMIM:614886)
PGM1-CDG (Orphanet:319646)
PMM2-CDG (Orphanet:79318)
POLYGLUCOSAN BODY MYOPATHY 1 WITH OR WITHOUT IMMUNODEFICIENCY (OMIM:615895)
PREECLAMPSIA/ECLAMPSIA 1 (OMIM:189800)
PROGRESSIVE EXTERNAL OPHTHALMOPLEGIA WITH MITOCHONDRIAL DNA DELETIONS,AUTOSOMAL DOMINANT, 4 (OMIM:610131)
PROTOPORPHYRIA, ERYTHROPOIETIC, X-LINKED (OMIM:300752)
Pearson syndrome (Orphanet:699)
Peroxisomal acyl-CoA oxidase deficiency (Orphanet:2971)
Polyarteritis nodosa, childhood-onset (OMIM:615688)
Polyglucosan body myopathy type 1 (ORPHA:397937)
Preeclampsia (Orphanet:275555)
Primary sclerosing cholangitis (Orphanet:171)
Progressive familial intrahepatic cholestasis type 3 (Orphanet:79305)
Psychomotor retardation due to S-adenosylhomocysteine hydrolase deficiency (Orphanet:88618)
Purine nucleoside phosphorylase deficiency (Orphanet:760)
Pyruvate dehydrogenase E3 deficiency (Orphanet:2394)
Renal cysts and diabetes syndrome (Orphanet:93111)
Renal tubulopathy - encephalopathy - liver failure (Orphanet:254902)
Retinal vasculopathy and cerebral leukodystrophy (Orphanet:247691)
Retinitis pigmentosa - intellectual deficit - deafness - hypogenitalism (Orphanet:3085)
Reynolds syndrome (Orphanet:779)
SRD5A3-CDG (Orphanet:324737)
Severe combined immunodeficiency due to adenosine deaminase deficiency (Orphanet:277)
Shwachman-Diamond syndrome (Orphanet:811)
Stevens-Johnson syndrome (Orphanet:36426)
TELANGIECTASIA, HEREDITARY HEMORRHAGIC, TYPE 5 (OMIM:615506)
TMEM165-CDG (Orphanet:314667)
TRAPS syndrome (Orphanet:32960)
Tyrosinemia type 1 (Orphanet:882)
Wolcott-Rallison syndrome (Orphanet:1667)
XFE PROGEROID SYNDROME (OMIM:610965)
[DEL] ARTHROGRYPOSIS, RENAL DYSFUNCTION, AND CHOLESTASIS 1 (OMIM:208085)
[DEL] GLYCOGEN STORAGE DISEASE Ib (OMIM:232220)