Botulism

General Information (adopted from Orphanet):

Synonyms, Signs:
Number of Symptoms 17
OrphanetNr: 1267
OMIM Id:
ICD-10: A05.1
UMLs: C0006057
MeSH: D001906
MedDRA: 10006041
Snomed: 398565003
414531002

Prevalence, inheritance and age of onset:

Prevalence: 0.05 of 100 000 [Orphanet]
Inheritance:
Age of onset: All ages
[Orphanet]

Disease classification (adopted from Orphanet):

Parent Diseases: Acquired neuromuscular junction disease
 -Rare neurologic disease
Rare bacterial infectious disease
 -Rare infectious disease

Symptom Information: Sort by abundance 

1
 (HPO:0011037) Decreased urine output Frequent [Orphanet] 47 / 7739
2
 (HPO:0000217) Xerostomia Very frequent [Orphanet] 35 / 7739
3
 (HPO:0000615) Abnormality of the pupil Very frequent [Orphanet] 39 / 7739
4
 (HPO:0000651) Diplopia Very frequent [Orphanet] 37 / 7739
5
 (HPO:0002015) Dysphagia Very frequent [Orphanet] 301 / 7739
6
 (HPO:0006824) Cranial nerve paralysis Very frequent [Orphanet] 81 / 7739
7
 (HPO:0002167) Neurological speech impairment Very frequent [Orphanet] 308 / 7739
8
 (HPO:0100021) Cerebral palsy Very frequent [Orphanet] 36 / 7739
9
 (HPO:0002019) Constipation Frequent [Orphanet] 194 / 7739
10
 (HPO:0006597) Diaphragmatic paralysis Very frequent [Orphanet] 16 / 7739
11
 (HPO:0002027) Abdominal pain Very frequent [Orphanet] 184 / 7739
12
 (HPO:0002017) Nausea and vomiting Frequent [Orphanet] 134 / 7739
13
 (HPO:0002014) Diarrhea Occasional [Orphanet] 225 / 7739
14
 (HPO:0011675) Arrhythmia Frequent [Orphanet] 226 / 7739
15
 (HPO:0002093) Respiratory insufficiency Frequent [Orphanet] 410 / 7739
16
 (HPO:0001324) Muscle weakness Very frequent [Orphanet] 859 / 7739
17
 (HPO:0001522) Death in infancy Occasional [Orphanet] 275 / 7739

Associated genes:

ClinVar (via SNiPA)

Gene symbol Variation Clinical significance Reference

Additional Information: