Carney triad

General Information (adopted from Orphanet):

Synonyms, Signs: GASTRIC LEIOMYOSARCOMA, PULMONARY CHONDROMA, AND EXTRAADRENAL PARAGANGLIOMA
Number of Symptoms 20
OrphanetNr: 139411
OMIM Id: 604287
ICD-10: D44.8
UMLs:
MeSH:
MedDRA:
Snomed:

Prevalence, inheritance and age of onset:

Prevalence: 150 cases [Orphanet]
Inheritance:
Age of onset: Adolescent
Adult
[Orphanet]

Disease classification (adopted from Orphanet):

Parent Diseases: Multiple polyglandular tumor
 -Rare endocrine disease
 -Rare genetic disease
 -Rare oncologic disease

Symptom Information: Sort by abundance 

1
 (HPO:0100634) Neuroendocrine neoplasm Very frequent [Orphanet] 8 / 7739
2
 (HPO:0002315) Headache Occasional [Orphanet] 175 / 7739
3
 (HPO:0008221) Adrenal hyperplasia Frequent [Orphanet] 24 / 7739
4
 (HPO:0002014) Diarrhea Very frequent [Orphanet] 225 / 7739
5
 (HPO:0002239) Gastrointestinal hemorrhage Very frequent [Orphanet] 97 / 7739
6
 (HPO:0001396) Cholestasis Frequent [Orphanet] 136 / 7739
7
 (HPO:0006753) Neoplasm of the stomach Very frequent [Orphanet] 13 / 7739
8
 (HPO:0001541) Ascites Frequent [Orphanet] 94 / 7739
9
 (HPO:0002039) Anorexia Occasional [Orphanet] 62 / 7739
10
 (HPO:0002017) Nausea and vomiting Very frequent [Orphanet] 134 / 7739
11
 (HPO:0002027) Abdominal pain Very frequent [Orphanet] 184 / 7739
12
 (HPO:0000822) Hypertension Occasional [Orphanet] 224 / 7739
13
 (HPO:0011675) Arrhythmia Occasional [Orphanet] 226 / 7739
14
 (HPO:0001903) Anemia Occasional [Orphanet] 289 / 7739
15
 (HPO:0100526) Neoplasm of the lung Very frequent [Orphanet] 26 / 7739
16
 (HPO:0100242) Sarcoma Very frequent [Orphanet] 27 / 7739
17
 (HPO:0002664) Neoplasm Very frequent [Orphanet] 111 / 7739
18
 (HPO:0002716) Lymphadenopathy Occasional [Orphanet] 129 / 7739
19
 (HPO:0001324) Muscle weakness Very frequent [Orphanet] 859 / 7739
20
 (HPO:0045026) Abnormality of the mediastinum Frequent [Orphanet] 6 / 7739

Associated genes:

ClinVar (via SNiPA)

Gene symbol Variation Clinical significance Reference

Additional Information: