Non-histaminic angioedema

General Information (adopted from Orphanet):

Synonyms, Signs: Angioneurotic edema
Bradykinine-induced angioedema
Non histamine-induced angioedema
Number of Symptoms 16
OrphanetNr: 658
OMIM Id:
ICD-10:
UMLs:
MeSH:
MedDRA:
Snomed:

Prevalence, inheritance and age of onset:

Prevalence: No data available.
Inheritance: Autosomal dominant
Not applicable
[Orphanet]
Age of onset: All ages
[Orphanet]

Disease classification (adopted from Orphanet):

Parent Diseases: Rare allergic disease
 -Rare allergic disease
Rare systemic or rheumatologic disease
 -Rare systemic or rheumatologic disease

Symptom Information: Sort by abundance 

1
 (HPO:0100820) Glomerulopathy Occasional [Orphanet] 46 / 7739
2
 (HPO:0000137) Abnormality of the ovary Occasional [Orphanet] 41 / 7739
3
 (HPO:0000606) Abnormality of the periorbital region Occasional [Orphanet] 96 / 7739
4
 (HPO:0009830) Peripheral neuropathy Occasional [Orphanet] 206 / 7739
5
 (HPO:0002014) Diarrhea Frequent [Orphanet] 225 / 7739
6
 (HPO:0001541) Ascites Occasional [Orphanet] 94 / 7739
7
 (HPO:0002017) Nausea and vomiting Frequent [Orphanet] 134 / 7739
8
 (HPO:0100665) Angioedema Very frequent [Orphanet] 14 / 7739
9
 (HPO:0000988) Skin rash Occasional [Orphanet] 98 / 7739
10
 (HPO:0000989) Pruritus Frequent [Orphanet] 111 / 7739
11
 (HPO:0004332) Abnormality of lymphocytes Occasional [Orphanet] 12 / 7739
12
 (HPO:0001909) Leukemia Occasional [Orphanet] 46 / 7739
13
 (HPO:0010741) Edema of the lower limbs Frequent [Orphanet] 34 / 7739
14
 (HPO:0100598) Pulmonary edema Frequent [Orphanet] 17 / 7739
15
 (HPO:0000969) Edema Very frequent [Orphanet] 117 / 7739
16
 (HPO:0001324) Muscle weakness Occasional [Orphanet] 859 / 7739

Associated genes:

ClinVar (via SNiPA)

Gene symbol Variation Clinical significance Reference

Additional Information: