Thrombocytopenia

Symptom Information:

Symptom ID: HPO:0001873
Synonyms:
Low platelet count [HPO:0001873]
Platelet count below reference range (finding) [Orphanet:48600]
Thrombocytopenic disorder (disorder) [Orphanet:48600]
Thrombocytopenia [Orphanet:48600]
Thrombocytopenia [OMIM:Thrombocytopenia]
Thrombocytopenia/thrombopenia [Orphanet:48600]
Thrombocytopenia [MedDRA:10043554]
Primary thrombocytopenia [MedDRA:10043554]
Secondary thrombocytopenia [MedDRA:10043554]
Thrombocytopaenia [MedDRA:10043554]
Thrombocytopenia aggravated [MedDRA:10043554]
Thrombocytopenia toxic [MedDRA:10043554]
Thrombocytopenia, unspecified [MedDRA:10043554]
Thrombopenia [MedDRA:10043554]
Persisting thrombocytopenia [MedDRA:10043554]
Chronic thrombocytopenia [MedDRA:10043554]
Thrombocytopenia (1 patient) [OMIM:Thrombocytopenia (1 patient)]
Thrombocytopenia (HELLP syndrome) [OMIM:Thrombocytopenia (HELLP syndrome)]
Thrombocytopenia (birth) [OMIM:Thrombocytopenia (birth)]
Thrombocytopenia (in some patients) [OMIM:Thrombocytopenia (in some patients)]
Thrombocytopenia (less common) [OMIM:Thrombocytopenia (less common)]
Thrombocytopenia (onset birth-neonate, may be precipitated by cow's milk allergy) [OMIM:Thrombocytopenia (onset birth-neonate, may be precipitated by cow's milk allergy)]
Thrombocytopenia (rare) [OMIM:Thrombocytopenia (rare)]
Thrombocytopenia (reported in 1 patient) [OMIM:Thrombocytopenia (reported in 1 patient)]
Thrombocytopenias [MedDRA:10043555]
Quality:
Cross references:
Orphanet:48600 "Thrombocytopenia/thrombopenia" [Orphanet:48600]
OMIM: "Thrombocytopenia" [OMIM:Thrombocytopenia]
OMIM: "Thrombocytopenia (1 patient)" [OMIM:Thrombocytopenia (1 patient)]
OMIM: "Thrombocytopenia (HELLP syndrome)" [OMIM:Thrombocytopenia (HELLP syndrome)]
OMIM: "Thrombocytopenia (birth)" [OMIM:Thrombocytopenia (birth)]
OMIM: "Thrombocytopenia (in some patients)" [OMIM:Thrombocytopenia (in some patients)]
OMIM: "Thrombocytopenia (less common)" [OMIM:Thrombocytopenia (less common)]
OMIM: "Thrombocytopenia (onset birth-neonate, may be precipitated by cow's milk allergy)" [OMIM:Thrombocytopenia (onset birth-neonate, may be precipitated by cow's milk allergy)]
OMIM: "Thrombocytopenia (rare)" [OMIM:Thrombocytopenia (rare)]
OMIM: "Thrombocytopenia (reported in 1 patient)" [OMIM:Thrombocytopenia (reported in 1 patient)]
UMLS:C0040034 "Thrombocytopenia" [Orphanet:48600]
Is a (Direct Parents):
Orphanet Abnormality of thrombocytes
HPO         Abnormal platelet count
HPO         Macrothrombocytopenia
MedDRA Abnormality of thrombocytes
Is a (Whole tree): HPO:
All(HPO:0000001)
    Phenotypic abnormality(HPO:0000118)
       Abnormality of blood and blood-forming tissues(HPO:0001871)
          Abnormality of thrombocytes(HPO:0001872)
             Abnormal platelet count(HPO:0011873)
                Thrombocytopenia(HPO:0001873)
MedDRA:
Blood and lymphatic system disorders(MedDRA:10005329)
    Abnormality of thrombocytes(HPO:0001872)
       Thrombocytopenia(HPO:0001873)
Database Frequency: 224 / 7739
Resource:

All diseases associated with this symptom:

16q24.3 microdeletion syndrome (Orphanet:261250)
22q11.2 deletion syndrome (Orphanet:567)
3-methylglutaconic aciduria type 4 (Orphanet:67048)
3-phosphoglycerate dehydrogenase deficiency (Orphanet:79351)
AICARDI-GOUTIERES SYNDROME 1 (OMIM:225750)
AICARDI-GOUTIERES SYNDROME 3 (OMIM:610329)
AICARDI-GOUTIERES SYNDROME 4 (OMIM:610333)
AICARDI-GOUTIERES SYNDROME 7 (OMIM:615846)
Action myoclonus - renal failure syndrome (Orphanet:163696)
Acyl-CoA dehydrogenase 9 deficiency (Orphanet:99901)
Adams-Oliver syndrome (Orphanet:974)
Alpha-thalassemia - myelodysplastic syndrome (Orphanet:231401)
Alport syndrome (Orphanet:63)
Atypical Gaucher disease due to saposin C deficiency (Orphanet:309252)
Atypical hemolytic uremic syndrome (Orphanet:2134)
Atypical hemolytic uremic syndrome with B factor anomaly (Orphanet:93578)
Atypical hemolytic uremic syndrome with C3 anomaly (Orphanet:93575)
Atypical hemolytic uremic syndrome with DGKE deficiency (Orphanet:357008)
Atypical hemolytic uremic syndrome with H factor anomaly (Orphanet:93579)
Atypical hemolytic uremic syndrome with I factor anomaly (Orphanet:93580)
Atypical hemolytic uremic syndrome with MCP/CD46 anomaly (Orphanet:93576)
Atypical hemolytic uremic syndrome with anti-factor H antibodies (Orphanet:93581)
Atypical hemolytic uremic syndrome with thrombomodulin anomaly (Orphanet:217023)
Autosomal recessive lymphoproliferative disease (Orphanet:238505)
Autosomal recessive severe congenital neutropenia due to G6PC3 deficiency (Orphanet:331176)
Autosomal thrombocytopenia with normal platelets (Orphanet:168629)
BERNARD-SOULIER SYNDROME (OMIM:231200)
BLEEDING DISORDER, PLATELET-TYPE, 15 (OMIM:615193)
BLEEDING DISORDER, PLATELET-TYPE, 17 (OMIM:187900)
BONE MARROW FAILURE SYNDROME 2 (OMIM:615715)
Babesiosis (Orphanet:108)
Beemer-Ertbruggen syndrome (Orphanet:1237)
Beta-thalassemia (Orphanet:848)
Beta-thalassemia - X-linked thrombocytopenia (Orphanet:231393)
Bilateral striopallidodentate calcinosis (Orphanet:1980)
Blackfan-Diamond anemia (Orphanet:124)
Bleeding diathesis due to a collagen receptor defect (Orphanet:73271)
Blue rubber bleb nevus (Orphanet:1059)
CREST syndrome (Orphanet:90290)
Castleman disease (Orphanet:160)
Central nervous system calcification - deafness - tubular acidosis - anemia (Orphanet:3240)
Cernunnos-XLF deficiency (Orphanet:169079)
Chédiak-Higashi syndrome (Orphanet:167)
Coats plus syndrome (Orphanet:313838)
Combined immunodeficiency due to CRAC channel dysfunction (Orphanet:169090)
Combined immunodeficiency due to STIM1 deficiency (Orphanet:317430)
Combined oxidative phosphorylation defect type 14 (Orphanet:319519)
Common variable immunodeficiency (Orphanet:1572)
Congenital amegakaryocytic thrombocytopenia (Orphanet:3319)
Congenital cataract-hypertrophic cardiomyopathy-mitochondrial myopathy syndrome (Orphanet:1369)
Congenital erythropoietic porphyria (Orphanet:79277)
Congenital intrauterine infection-like syndrome (Orphanet:1229)
Congenital rubella syndrome (Orphanet:290)
Congenital short bowel syndrome (Orphanet:2301)
Congenital thrombotic thrombocytopenic purpura due to ADAMTS-13 deficiency (Orphanet:93583)
Congenital toxoplasmosis (Orphanet:858)
Constitutional megaloblastic anemia with severe neurologic disease (Orphanet:319651)
Cornelia de Lange syndrome (Orphanet:199)
Crimean-Congo hemorrhagic fever (Orphanet:99827)
Cyclic neutropenia (Orphanet:2686)
DIAMOND-BLACKFAN ANEMIA 1 (OMIM:105650)
DYSKERATOSIS CONGENITA, AUTOSOMAL DOMINANT, 1 (OMIM:127550)
DYSKERATOSIS CONGENITA, AUTOSOMAL DOMINANT, 2 (OMIM:613989)
DYSKERATOSIS CONGENITA, AUTOSOMAL DOMINANT, 3 (OMIM:613990)
DYSKERATOSIS CONGENITA, AUTOSOMAL RECESSIVE, 1 (OMIM:224230)
DYSKERATOSIS CONGENITA, AUTOSOMAL RECESSIVE, 2 (OMIM:613987)
Deafness - lymphedema - leukemia (Orphanet:3226)
Dengue fever (Orphanet:99828)
Diabetic embryopathy (Orphanet:1926)
Diffuse neonatal hemangiomatosis (Orphanet:2123)
Dubowitz syndrome (Orphanet:235)
Dyskeratosis congenita (Orphanet:1775)
ENCEPHALOMYOPATHY, MITOCHONDRIAL, DUE TO VOLTAGE-DEPENDENT ANION CHANNELDEFICIENCY (OMIM:614520)
EPSTEIN SYNDROME (OMIM:153650)
Early-onset familial noncirrhotic portal hypertension (ORPHA:494348)
Ebola hemorrhagic fever (Orphanet:319218)
FANCONI ANEMIA, COMPLEMENTATION GROUP A (OMIM:227650)
FANCONI ANEMIA, COMPLEMENTATION GROUP C (OMIM:227645)
FANCONI ANEMIA, COMPLEMENTATION GROUP D2 (OMIM:227646)
FANCONI ANEMIA, COMPLEMENTATION GROUP E (OMIM:600901)
FANCONI ANEMIA, COMPLEMENTATION GROUP G (OMIM:614082)
FECHTNER SYNDROME (OMIM:153640)
FORSYTHE-WAKELING SYNDROME (OMIM:613606)
Familial hemophagocytic lymphohistiocytosis (Orphanet:540)
Familial platelet syndrome with predisposition to acute myelogenous leukemia (Orphanet:71290)
Fanconi anemia (Orphanet:84)
Felty syndrome (Orphanet:47612)
Fetal Gaucher disease (Orphanet:85212)
Fetal parvovirus syndrome (Orphanet:295)
GIANT PLATELET SYNDROME WITH THROMBOCYTOPENIA (OMIM:137560)
Gamma heavy-chain disease (Orphanet:100026)
Gaucher disease (Orphanet:355)
Gaucher disease type 1 (Orphanet:77259)
Gaucher disease type 2 (Orphanet:77260)
Gaucher disease type 3 (Orphanet:77261)
Ghosal hematodiaphyseal dysplasia (Orphanet:1802)
Good syndrome (Orphanet:169105)
Gray platelet syndrome (Orphanet:721)
Griscelli disease (Orphanet:381)
HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS, FAMILIAL, 1 (OMIM:267700)
HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS, FAMILIAL, 2 (OMIM:603553)
HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS, FAMILIAL, 4 (OMIM:603552)
HERMANSKY-PUDLAK SYNDROME 5 (OMIM:614074)
Hemorrhagic fever - renal syndrome (Orphanet:340)
Hereditary folate malabsorption (Orphanet:90045)
Hermansky-Pudlak syndrome with neutropenia (Orphanet:183678)
Holocarboxylase synthetase deficiency (Orphanet:79242)
Hoyeraal-Hreidarsson syndrome (Orphanet:3322)
Hyperuricemia-pulmonary hypertension-renal failure-alkalosis syndrome (Orphanet:363694)
IMMUNODEFICIENCY, COMMON VARIABLE, 8, WITH AUTOIMMUNITY (OMIM:614700)
INTESTINAL PSEUDOOBSTRUCTION, NEURONAL, CHRONIC IDIOPATHIC, X-LINKED (OMIM:300048)
IVIC syndrome (Orphanet:2307)
Immune dysregulation-polyendocrinopathy-enteropathy-X-linked syndrome (Orphanet:37042)
Immune thrombocytopenic purpura (Orphanet:3002)
Immunoglobulin-mediated membranoproliferative glomerulonephritis (Orphanet:329903)
Isolated agammaglobulinemia (Orphanet:229717)
Isovaleric acidemia (Orphanet:33)
Jacobsen syndrome (Orphanet:2308)
Kasabach-Merritt syndrome (Orphanet:2330)
LYMPHOPROLIFERATIVE SYNDROME 1 (OMIM:613011)
LYMPHOPROLIFERATIVE SYNDROME, X-LINKED, 1 (OMIM:308240)
Lassa fever (Orphanet:99824)
Lathosterolosis (Orphanet:46059)
Letterer-Siwe disease (Orphanet:99870)
Lyell syndrome (Orphanet:537)
Lysinuric protein intolerance (Orphanet:470)
MAY-HEGGLIN ANOMALY (OMIM:155100)
MONOSOMY 7 OF BONE MARROW (OMIM:252270)
MYH9-related thrombocytopenia (Orphanet:182050)
Marburg hemorrhagic fever (Orphanet:99826)
Methylmalonic acidemia with homocystinuria (Orphanet:26)
Methylmalonic acidemia with homocystinuria, type cblC (Orphanet:79282)
Methylmalonic acidemia with homocystinuria, type cblF (Orphanet:79284)
Methylmalonic acidemia with homocystinuria, type cblJ (Orphanet:369955)
Mevalonic aciduria (Orphanet:29)
Mitochondrial DNA depletion syndrome, hepatocerebral form due to DGUOK deficiency (Orphanet:279934)
Myopathy, lactic acidosis, and sideroblastic anemia 2; MLASA2 (OMIM:613561)
NOONAN SYNDROME 1 (OMIM:163950)
Neonatal hemochromatosis (Orphanet:446)
Nijmegen breakage syndrome (Orphanet:647)
Noonan syndrome (Orphanet:648)
Noonan syndrome-like disorder with juvenile myelomonocytic leukemia (Orphanet:363972)
OSTEOCHONDRODYSPLASIA, RHIZOMELIC, WITH CALLOSAL AGENESIS, THROMBOCYTOPENIA,HYDROCEPHALUS, AND HYPERTENSION (OMIM:166990)
OSTEOPETROSIS, AUTOSOMAL RECESSIVE 2 (OMIM:259710)
OSTEOPETROSIS, AUTOSOMAL RECESSIVE 8 (OMIM:615085)
Oculocerebrorenal syndrome (Orphanet:534)
Omenn syndrome (Orphanet:39041)
Osteogenesis imperfecta (Orphanet:666)
Osteopetrosis (Orphanet:2781)
Osteopetrosis with renal tubular acidosis (Orphanet:2785)
PANCYTOPENIA AND OCCLUSIVE VASCULAR DISEASE (OMIM:167850)
PELGER-HUET ANOMALY (OMIM:169400)
PLATELET DISORDER, UNDEFINED (OMIM:173420)
PLATELET GLYCOPROTEIN IV DEFICIENCY (OMIM:608404)
PLATELET SIGNAL PROCESSING DEFECT (OMIM:173590)
PREECLAMPSIA/ECLAMPSIA 1 (OMIM:189800)
Paris-Trousseau thrombocytopenia (Orphanet:851)
Pearson syndrome (Orphanet:699)
Pediatric systemic lupus erythematosus (Orphanet:93552)
Polyarteritis nodosa, childhood-onset (OMIM:615688)
Polycythemia vera (Orphanet:729)
Preeclampsia (Orphanet:275555)
Primary hypereosinophilic syndrome (Orphanet:314950)
Prolidase deficiency (Orphanet:742)
Propionic acidemia (Orphanet:35)
Psychomotor retardation due to S-adenosylhomocysteine hydrolase deficiency (Orphanet:88618)
Quebec platelet disorder (Orphanet:220436)
Radio-ulnar synostosis - amegakaryocytic thrombocytopenia (Orphanet:71289)
Recurrent infections-myelofibrosis-nephromegaly syndrome (Orphanet:369852)
Reticular dysgenesis (Orphanet:33355)
Retinopathy - anemia- central nervous system anomalies (Orphanet:3088)
Rhabdoid tumor (Orphanet:69077)
Roberts syndrome (Orphanet:3103)
SEBASTIAN SYNDROME (OMIM:605249)
SLC35A1-CDG (Orphanet:238459)
STT3B-CDG (Orphanet:370924)
SYSTEMIC LUPUS ERYTHEMATOSUS (OMIM:152700)
Schimke immuno-osseous dysplasia (Orphanet:1830)
Sea-blue histiocytosis (Orphanet:158029)
Severe combined immunodeficiency due to adenosine deaminase deficiency (Orphanet:277)
Shwachman-Diamond syndrome (Orphanet:811)
Stevens-Johnson syndrome (Orphanet:36426)
Stormorken-Sjaastad-Langslet syndrome (Orphanet:3204)
Sweet syndrome (Orphanet:3243)
Systemic mastocytosis (Orphanet:2467)
THROMBOCYTOPENIA 3 (OMIM:273900)
THROMBOCYTOPENIA 4 (OMIM:612004)
THROMBOCYTOPENIA 5 (OMIM:616216)
THROMBOCYTOPENIA WITH ELEVATED SERUM IgA AND RENAL DISEASE (OMIM:314000)
THROMBOCYTOPENIA, CYCLIC (OMIM:188020)
TMEM165-CDG (Orphanet:314667)
Thiamine-responsive megaloblastic anemia syndrome (Orphanet:49827)
Thrombocytopenia - Robin sequence (Orphanet:3323)
Thrombocytopenia - absent radius (Orphanet:3320)
Thrombocytopenia with congenital dyserythropoietic anemia (Orphanet:67044)
Thrombotic thrombocytopenic purpura (Orphanet:54057)
Thyrocerebrorenal syndrome (Orphanet:3327)
Transaldolase deficiency (Orphanet:101028)
Transcobalamin deficiency (Orphanet:859)
Typical hemolytic uremic syndrome (Orphanet:90038)
Tyrosinemia type 1 (Orphanet:882)
Viral hemorrhagic fever (Orphanet:341)
Vitamin B12-responsive methylmalonic acidemia (Orphanet:28)
Vitamin B12-responsive methylmalonic acidemia type cblA (Orphanet:79310)
Vitamin B12-responsive methylmalonic acidemia type cblB (Orphanet:79311)
Vitamin B12-unresponsive methylmalonic acidemia (Orphanet:27)
Vitamin B12-unresponsive methylmalonic acidemia type mut- (Orphanet:79312)
Vitamin B12-unresponsive methylmalonic acidemia type mut0 (Orphanet:289916)
Von Voss-Cherstvoy syndrome (Orphanet:3439)
Von Willebrand disease type 3 (Orphanet:166096)
WISKOTT-ALDRICH SYNDROME (OMIM:277970)
WISKOTT-ALDRICH SYNDROME (OMIM:301000)
WISKOTT-ALDRICH SYNDROME 2 (OMIM:614493)
WISKOTT-ALDRICH SYNDROME, AUTOSOMAL DOMINANT FORM (OMIM:600903)
WT limb-blood syndrome (Orphanet:3466)
Wiskott-Aldrich syndrome (Orphanet:906)
Wolfram syndrome 1 (OMIM:222300)
Wolfram syndrome, mitochondrial form (OMIM:598500)
X-linked Alport syndrome (Orphanet:88917)
X-linked agammaglobulinemia (Orphanet:47)
X-linked dyserythropoetic anemia with abnormal platelets and neutropenia (Orphanet:363727)
X-linked hyper-IgM syndrome (Orphanet:101088)
[DEL] NEUTROPENIA, SEVERE CONGENITAL, 4, AUTOSOMAL RECESSIVE; SCN4 (OMIM:612541)
[DEL] SENGERS SYNDROME (OMIM:212350)