Delayed speech and language development
Symptom Information:
Symptom ID: | HPO:0000750 | |||||||||||||||||||||||||||||||||||||||||
Synonyms: |
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Cross references: |
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Is a (Direct Parents): |
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Is a (Whole tree): |
HPO:
All(HPO:0000001) Phenotypic abnormality(HPO:0000118) Abnormality of the nervous system(HPO:0000707) Abnormality of nervous system physiology(HPO:0012638) Abnormality of higher mental function(HPO:0011446) Cognitive impairment(HPO:0100543) Delayed speech and language development(HPO:0000750) MedDRA: |
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Database Frequency: | 197 / 7739 | |||||||||||||||||||||||||||||||||||||||||
Resource: |
All diseases associated with this symptom:
15q11q13 microduplication syndrome | (Orphanet:238446) |
15q24 microdeletion syndrome | (Orphanet:94065) |
17p11.2 microduplication syndrome | (Orphanet:1713) |
17q11 microdeletion syndrome | (Orphanet:97685) |
17q11.2 microduplication syndrome | (Orphanet:139474) |
17q12 microdeletion syndrome | (Orphanet:261265) |
1p36 deletion syndrome | (Orphanet:1606) |
2-aminoadipic 2-oxoadipic aciduria | (Orphanet:79154) |
22q11.2 deletion syndrome | (Orphanet:567) |
22q11.2 microduplication syndrome | (Orphanet:1727) |
2q32q33 microdeletion syndrome | (Orphanet:251019) |
3-methylglutaconic aciduria type 1 | (Orphanet:67046) |
3-methylglutaconic aciduria type 3 | (Orphanet:67047) |
3q13 microdeletion syndrome | (Orphanet:1621) |
4-hydroxybutyric aciduria | (Orphanet:22) |
ACRODYSOSTOSIS 2 WITH OR WITHOUT HORMONE RESISTANCE | (OMIM:614613) |
AGAMMAGLOBULINEMIA, X-LINKED | (OMIM:300755) |
AUTISM | (OMIM:209850) |
AUTISM, SUSCEPTIBILITY TO, 3 | (OMIM:608049) |
AUTISM, SUSCEPTIBILITY TO, 8 | (OMIM:607373) |
AUTISM, SUSCEPTIBILITY TO, X-LINKED 1 | (OMIM:300425) |
AUTISM, SUSCEPTIBILITY TO, X-LINKED 2 | (OMIM:300495) |
AUTISM, SUSCEPTIBILITY TO, X-LINKED 3 | (OMIM:300496) |
Ablepharon macrostomia syndrome | (Orphanet:920) |
Adenylosuccinate lyase deficiency | (Orphanet:46) |
Alström syndrome | (Orphanet:64) |
Arginine:glycine amidinotransferase deficiency | (Orphanet:35704) |
Aspartylglucosaminuria | (Orphanet:93) |
Autosomal recessive cerebelloparenchymal disorder type 3 | (Orphanet:1170) |
Autosomal recessive dopa-responsive dystonia | (Orphanet:101150) |
Autosomal recessive limb-girdle muscular dystrophy type 2P | (Orphanet:280333) |
Autosomal recessive spastic ataxia - optic atrophy - dysarthria | (Orphanet:254343) |
Autosomal recessive spastic paraplegia type 45 | (Orphanet:320396) |
Autosomal recessive spastic paraplegia type 53 | (Orphanet:319199) |
BARATELA-SCOTT SYNDROME | (OMIM:300881) |
Bannayan-Riley-Ruvalcaba syndrome | (Orphanet:109) |
Bardet-Biedl syndrome | (Orphanet:110) |
Bardet-Biedl syndrome 1 | (OMIM:209900 ) |
Bardet-Biedl syndrome 10 | (OMIM:615987) |
Bardet-Biedl syndrome 2 | (OMIM:615981) |
Bardet-Biedl syndrome 4 | (OMIM:615982) |
Bardet-Biedl syndrome 7 | (OMIM:615984) |
Bardet-Biedl syndrome 9 | (OMIM:615986) |
Beckwith-Wiedemann syndrome due to imprinting defect of 11p15 | (Orphanet:231117) |
Bilateral polymicrogyria | (Orphanet:268940) |
CEREBELLAR ATAXIA, MENTAL RETARDATION, AND DYSEQUILIBRIUM SYNDROME1 | (OMIM:224050) |
CEREBELLAR ATAXIA, MENTAL RETARDATION, AND DYSEQUILIBRIUM SYNDROME2 | (OMIM:610185) |
CHROMOSOME 15q11.2 DELETION SYNDROME | (OMIM:615656) |
CHROMOSOME 16p12.1 DELETION SYNDROME, 520-KBFRAGILE SITE, DISTAMYCIN A TYPE, RARE, FRA(16)(p12.1), INCLUDED | (OMIM:136570) |
CHROMOSOME 5q12 DELETION SYNDROME | (OMIM:615668) |
CHROMOSOME Xp11.22 DUPLICATION SYNDROME | (OMIM:300705) |
CK syndrome | (Orphanet:251383) |
CLN2 disease | (Orphanet:228349) |
CLN7 disease | (Orphanet:228366) |
CLN8 disease | (Orphanet:228354) |
COMBINED OXIDATIVE PHOSPHORYLATION DEFICIENCY 18 | (OMIM:615578) |
CONGENITAL CONTRACTURES OF THE LIMBS AND FACE, HYPOTONIA, AND DEVELOPMENTALDELAY | (OMIM:616266) |
CORNELIA DE LANGE SYNDROME 1 | (OMIM:122470) |
CORTICAL DYSPLASIA, COMPLEX, WITH OTHER BRAIN MALFORMATIONS 6 | (OMIM:615771) |
Childhood apraxia of speech | (Orphanet:209908) |
Combined oxidative phosphorylation defect type 15 | (Orphanet:319524) |
Congenital lactic acidosis, Saguenay-Lac-St. Jean type | (Orphanet:70472) |
Congenital muscular dystrophy due to phosphatidylcholine biosynthesis defect | (Orphanet:280671) |
Cornelia de Lange syndrome | (Orphanet:199) |
Cortical dysgenesis with pontocerebellar hypoplasia due to TUBB3 mutation | (Orphanet:300570) |
Costello syndrome | (Orphanet:3071) |
Cystic leukoencephalopathy without megalencephaly | (Orphanet:85136) |
DEAFNESS, AUTOSOMAL RECESSIVE 79 | (OMIM:613307) |
DIGEORGE SYNDROME | (OMIM:188400) |
DYSKERATOSIS CONGENITA, AUTOSOMAL DOMINANT, 3 | (OMIM:613990) |
DYSTONIA WITH RINGBINDEN | (OMIM:224550) |
Delayed speech - facial asymmetry - strabismus - ear lobe creases | (Orphanet:3038) |
Dihydropyrimidine dehydrogenase deficiency | (Orphanet:1675) |
Dihydropyrimidinuria | (Orphanet:38874) |
Distal monosomy 10q | (Orphanet:96148) |
Distal monosomy 6p | (Orphanet:96125) |
Dubowitz syndrome | (Orphanet:235) |
Duchenne muscular dystrophy | (Orphanet:98896) |
Dyschromatosis symmetrica hereditaria | (Orphanet:41) |
Dysequilibrium syndrome | (Orphanet:1766) |
Dystonia 16 | (Orphanet:210571) |
EAST syndrome | (Orphanet:199343) |
ECTODERMAL DYSPLASIA SYNDROME WITH DISTINCTIVE FACIAL APPEARANCE ANDPREAXIAL POLYDACTYLY OF FEET | (OMIM:129540) |
ENCEPHALOPATHY, PROGRESSIVE, WITH OR WITHOUT LIPODYSTROPHY | (OMIM:615924) |
Emanuel syndrome | (Orphanet:96170) |
Encephalopathy due to GLUT1 deficiency | (Orphanet:71277) |
Epileptic encephalopathy with continuous spike-and-wave during sleep | (Orphanet:725) |
FG SYNDROME 2 | (OMIM:300321) |
FORSYTHE-WAKELING SYNDROME | (OMIM:613606) |
FRAXE intellectual deficit | (Orphanet:100973) |
Familial hyperthyroidism due to mutations in TSH receptor | (Orphanet:424) |
Fucosidosis | (Orphanet:349) |
Galactose epimerase deficiency | (Orphanet:79238) |
Generalized resistance to thyroid hormone | (Orphanet:3221) |
Geroderma osteodysplastica | (Orphanet:2078) |
Glycogen storage disease due to phosphoglycerate kinase 1 deficiency | (Orphanet:713) |
Growth delay due to insulin-like growth factor I resistance | (Orphanet:73273) |
Grubben-de Cock-Borghgraef syndrome | (Orphanet:2101) |
Guanidinoacetate methyltransferase deficiency | (Orphanet:382) |
HYPERPHOSPHATASIA WITH MENTAL RETARDATION SYNDROME 1 | (OMIM:239300) |
HYPERPHOSPHATASIA WITH MENTAL RETARDATION SYNDROME 2 | (OMIM:614749) |
Hurler syndrome | (Orphanet:93473) |
Hyperlysinemia, type I | (OMIM:238700) |
Hypermethioninemia encephalopathy due to adenosine kinase deficiency | (Orphanet:289290) |
Hypohidrosis-enamel hypoplasia-palmoplantar keratoderma-intellectual disability syndrome | (Orphanet:363523) |
Hypomyelination with atrophy of basal ganglia and cerebellum | (Orphanet:139441) |
Infantile-onset autosomal recessive nonprogressive cerebellar ataxia | (Orphanet:284332) |
Intellectual deficit, X-linked - psychosis - macroorchidism | (Orphanet:3077) |
Intellectual deficit, X-linked, Brooks type | (Orphanet:3056) |
Intellectual deficit, X-linked, Wilson type | (Orphanet:85290) |
Intellectual disability-developmental delay-contractures syndrome | (Orphanet:3454) |
Isobutyryl-CoA dehydrogenase deficiency | (Orphanet:79159) |
Isolated congenital hypoglossia/aglossia | (Orphanet:141152) |
Kleefstra syndrome | (Orphanet:261494) |
Koolen-De Vries syndrome | (Orphanet:96169) |
Kostmann syndrome | (Orphanet:99749) |
Landau-Kleffner syndrome | (Orphanet:98818) |
Langer-Giedion syndrome | (Orphanet:502) |
Late infantile neuronal ceroid lipofuscinosis | (Orphanet:168491) |
Leigh syndrome | (Orphanet:506) |
Lymphedema - atrial septal defects - facial changes | (Orphanet:86915) |
MACROCEPHALY/MEGALENCEPHALY SYNDROME, AUTOSOMAL RECESSIVE | (OMIM:248000) |
MAXILLOFACIAL DYSOSTOSIS | (OMIM:155000) |
MEGDEL syndrome | (Orphanet:352328) |
MENTAL RETARDATION WITH LANGUAGE IMPAIRMENT AND WITH OR WITHOUT AUTISTICFEATURES | (OMIM:613670) |
MENTAL RETARDATION, ANTERIOR MAXILLARY PROTRUSION, AND STRABISMUS | (OMIM:613671) |
MENTAL RETARDATION, AUTOSOMAL DOMINANT 23 | (OMIM:615761) |
MENTAL RETARDATION, AUTOSOMAL RECESSIVE 39 | (OMIM:615541) |
MENTAL RETARDATION, AUTOSOMAL RECESSIVE 5 | (OMIM:611091) |
MENTAL RETARDATION, OBESITY, MANDIBULAR PROGNATHISM, AND EYE AND SKINANOMALIES | (OMIM:606772) |
MENTAL RETARDATION, TRUNCAL OBESITY, RETINAL DYSTROPHY, AND MICROPENISSYNDROME | (OMIM:610156) |
MENTAL RETARDATION, X-LINKED 19 | (OMIM:300844) |
MENTAL RETARDATION, X-LINKED 30 | (OMIM:300558) |
MENTAL RETARDATION, X-LINKED 89 | (OMIM:300848) |
MENTAL RETARDATION, X-LINKED 9 | (OMIM:309549) |
MENTAL RETARDATION, X-LINKED 90 | (OMIM:300850) |
MENTAL RETARDATION, X-LINKED 93 | (OMIM:300659) |
MENTAL RETARDATION, X-LINKED 95 | (OMIM:300716) |
MICROCEPHALY 2, PRIMARY, AUTOSOMAL RECESSIVE, WITH OR WITHOUT CORTICALMALFORMATIONS | (OMIM:604317) |
MICROCEPHALY 5, PRIMARY, AUTOSOMAL RECESSIVE | (OMIM:608716) |
Mandibulofacial dysostosis-microcephaly syndrome | (Orphanet:79113) |
Moebius syndrome | (Orphanet:570) |
Monosomy 13q14 | (Orphanet:1587) |
Monosomy 22q13 | (Orphanet:48652) |
Monosomy 5p | (Orphanet:281) |
Monosomy 9p | (Orphanet:261112) |
Mucopolysaccharidosis type 2 | (Orphanet:580) |
NEURODEGENERATION WITH BRAIN IRON ACCUMULATION 2B | (OMIM:610217) |
NOONAN SYNDROME 6 | (OMIM:613224) |
Nager syndrome | (Orphanet:245) |
Nephronophthisis 18 | (OMIM:615862) |
Neurodegeneration with brain iron accumulation due to C19orf12 mutation | (Orphanet:289560) |
Non-progressive cerebellar ataxia with intellectual deficit | (Orphanet:314647) |
Noonan syndrome-like disorder with juvenile myelomonocytic leukemia | (Orphanet:363972) |
Osteoglophonic dwarfism | (Orphanet:2645) |
Osteopathia striata - cranial sclerosis | (Orphanet:2780) |
PELIZAEUS-MERZBACHER DISEASE | (OMIM:312080) |
PERIVENTRICULAR NODULAR HETEROTOPIA 6 | (OMIM:615544) |
PEROXISOME BIOGENESIS DISORDER 1B | (OMIM:601539) |
PLANTAR LIPOMATOSIS, UNUSUAL FACIES, AND DEVELOPMENTAL DELAY | (OMIM:602342) |
PORETTI-BOLTSHAUSER SYNDROME | (OMIM:615960) |
PYCR1-related DeBarsy syndrome | (Orphanet:293633) |
Partington syndrome | (Orphanet:94083) |
Pitt-Hopkins-like syndrome 2 | (OMIM:614325) |
Prader-Willi syndrome | (Orphanet:739) |
Purine nucleoside phosphorylase deficiency | (Orphanet:760) |
Pyridoxine-dependent epilepsy | (Orphanet:3006) |
Pyruvate dehydrogenase E3-binding protein deficiency | (Orphanet:255182) |
Rolandic epilepsy - speech dyspraxia | (Orphanet:163721) |
Rubinstein-Taybi syndrome due to CREBBP mutations | (Orphanet:353277) |
Rubinstein-Taybi syndrome due to EP300 haploinsufficiency | (Orphanet:353284) |
SECKEL SYNDROME 6 | (OMIM:614728) |
SHORT syndrome | (Orphanet:3163) |
SPASTIC PARAPLEGIA 47, AUTOSOMAL RECESSIVE | (OMIM:614066) |
SPECIFIC LANGUAGE IMPAIRMENT 1 | (OMIM:606711) |
SPECIFIC LANGUAGE IMPAIRMENT 2 | (OMIM:606712) |
Saccharopinuria | (Orphanet:3124) |
Salla disease | (Orphanet:309334) |
Short chain 3-hydroxyacyl-CoA dehydrogenase deficiency | (Orphanet:35123) |
Short chain acyl-CoA dehydrogenase deficiency | (Orphanet:26792) |
Short-rib thoracic dysplasia 11 with or without polydactyly | (OMIM:615633) |
Smith-Magenis syndrome | (Orphanet:819) |
Spectrin-associated autosomal recessive cerebellar ataxia | (Orphanet:352403) |
Steinert myotonic dystrophy | (Orphanet:273) |
TEMPLE SYNDROME | (OMIM:616222) |
TENORIO SYNDROME | (OMIM:616260) |
THYROID HORMONE RESISTANCE, GENERALIZED, AUTOSOMAL DOMINANT | (OMIM:188570) |
TREACHER COLLINS SYNDROME 2 | (OMIM:613717) |
Transketolase deficiency | (ORPHA:488618) |
Weaver syndrome | (Orphanet:3447) |
Wiedemann-Steiner syndrome | (Orphanet:319182) |
Wilson-Turner syndrome | (Orphanet:3459) |
Wrinkly skin syndrome | (Orphanet:2834) |
X-linked creatine transporter deficiency | (Orphanet:52503) |
X-linked intellectual deficit - cerebellar hypoplasia | (Orphanet:137831) |
X-linked intellectual disability, Hedera type | (Orphanet:93952) |
[DEL] NEUROFIBROMATOSIS-NOONAN SYNDROME | (OMIM:601321) |