SPECIFIC LANGUAGE IMPAIRMENT 1

General Information (adopted from Orphanet):

Synonyms, Signs: SPECIFIC LANGUAGE IMPAIRMENT QUANTITATIVE TRAIT LOCUS ON CHROMOSOME 16
SLI1
Number of Symptoms 10
OrphanetNr:
OMIM Id: 606711
ICD-10:
UMLs:
MeSH:
MedDRA:
Snomed:

Prevalence, inheritance and age of onset:

Prevalence: No data available.
Inheritance: Multifactorial
[Omim]
Age of onset:

Disease classification (adopted from Orphanet):

Parent Diseases: No data available.

Symptom Information: Sort by abundance 

1
(HPO:0002463) Language impairment 15 / 7739
2
(HPO:0000750) Delayed speech and language development 197 / 7739
3
(HPO:0002549) Deficit in phonologic short-term memory 2 / 7739
4
(HPO:0002526) Deficit in nonword repetition 2 / 7739
5
(OMIM) Deficit in reading comprehension 1 / 7739
6
(OMIM) Normal intelligence 81 / 7739
7
(HPO:0001426) Multifactorial inheritance 37 / 7739
8
(OMIM) No other neurologic deficits 2 / 7739
9
(OMIM) Deficit in spelling 1 / 7739
10
(OMIM) Deficit in basic reading 1 / 7739

Associated genes:

ClinVar (via SNiPA)

Gene symbol Variation Clinical significance Reference

Additional Information:

Description: (OMIM) Specific language impairment (SLI) is a common developmental disorder characterized by difficulty in language acquisition despite otherwise normal development and in the absence of any obvious explanatory factors. This disorder affects 5 to 8% of preschool children and ...