Narrow mouth

Symptom Information:

Symptom ID: HPO:0000160
Synonyms:
Microstomia [HPO:0000160]
Small mouth [HPO:0000160]
Small oral aperture [HPO:0000160]
Microstomia [OMIM:Microstomia]
Narrow mouth [OMIM:Narrow mouth]
Microstomia/little mouth [Orphanet:9080]
Microstomia (52%) [OMIM:Microstomia (52%)]
Small mouth [OMIM:Small mouth]
Small mouth (in 1 family) [OMIM:Small mouth (in 1 family)]
Small mouth (rare) [OMIM:Small mouth (rare)]
Microstomia [MedDRA:10027553]
Quality:
Cross references:
Orphanet:9080 "Microstomia/little mouth" [Orphanet:9080]
OMIM: "Microstomia" [OMIM:Microstomia]
OMIM: "Narrow mouth" [OMIM:Narrow mouth]
OMIM: "Microstomia (52%)" [OMIM:Microstomia (52%)]
OMIM: "Small mouth" [OMIM:Small mouth]
OMIM: "Small mouth (in 1 family)" [OMIM:Small mouth (in 1 family)]
OMIM: "Small mouth (rare)" [OMIM:Small mouth (rare)]
UMLS:C0026034 "Microstomia" [HPO:0000160]
Is a (Direct Parents):
Orphanet Abnormality of the mouth
HPO         Abnormality of mouth size
MedDRA Musculoskeletal and connective tissue disorders of face, neck and jaw congenital
Is a (Whole tree): HPO:
All(HPO:0000001)
    Phenotypic abnormality(HPO:0000118)
       Abnormality of head or neck(HPO:0000152)
          Abnormality of the head(HPO:0000234)
             Abnormality of the face(HPO:0000271)
                Abnormality of the mouth(HPO:0000153)
                   Abnormality of mouth size(HPO:0011337)
                      Narrow mouth(HPO:0000160)
MedDRA:
Musculoskeletal and connective tissue disorders(MedDRA:10028395)
    Musculoskeletal and connective tissue disorders congenital(MedDRA:10028396)
       Musculoskeletal and connective tissue disorders of face, neck and jaw congenital(MedDRA:10028380)
          Narrow mouth(HPO:0000160)
Database Frequency: 188 / 7739
Resource:

All diseases associated with this symptom:

14q11.2 microdeletion syndrome (Orphanet:261120)
15q24 microdeletion syndrome (Orphanet:94065)
17p13.3 microduplication syndrome (Orphanet:217385)
17q23.1q23.2 microdeletion syndrome (Orphanet:261279)
1p36 deletion syndrome (Orphanet:1606)
20p12.3 microdeletion syndrome (Orphanet:261295)
2p15p16.1 microdeletion syndrome (Orphanet:261349)
2q32q33 microdeletion syndrome (Orphanet:251019)
8q12 microduplication syndrome (Orphanet:228399)
8q21.11 microdeletion syndrome (Orphanet:284160)
8q22.1 microdeletion syndrome (Orphanet:178303)
ALDH18A1-related De Barsy syndrome (Orphanet:35664)
AREDYLD syndrome (Orphanet:1133)
ARTHROGRYPOSIS, DISTAL, TYPE 2A (OMIM:193700)
ARTHROGRYPOSIS, DISTAL, TYPE 2E (OMIM:121070)
AURICULOCONDYLAR SYNDROME 1 (OMIM:602483)
AURICULOCONDYLAR SYNDROME 2 (OMIM:614669)
Acrofacial dysostosis, Rodriguez type (Orphanet:1788)
Acromicric dysplasia (Orphanet:969)
Acroosteolysis, dominant type (Orphanet:955)
Agnathia - holoprosencephaly - situs inversus (Orphanet:990)
Antley-Bixler syndrome (Orphanet:83)
Aortic arch anomaly - peculiar facies - intellectual deficit (Orphanet:1110)
Arachnodactyly - intellectual deficit - dysmorphism (Orphanet:1130)
Arthrogryposis multiplex congenita - whistling face (Orphanet:1150)
Auriculocondylar syndrome (Orphanet:137888)
Autosomal recessive cutis laxa type 2 (Orphanet:90350)
Autosomal recessive cutis laxa type 2, classic type (Orphanet:357074)
Autosomal recessive cutis laxa type 2A (Orphanet:357058)
Autosomal recessive multiple pterygium syndrome (Orphanet:2990)
Baller-Gerold syndrome (Orphanet:1225)
Bartsocas-Papas syndrome (Orphanet:1234)
Blepharophimosis-intellectual deficit syndrome due to UBE3B deficiency (Orphanet:329255)
Blepharophimosis-intellectual deficit syndrome, MKB type (Orphanet:293707)
Blepharophimosis-intellectual deficit syndrome, Ohdo type (Orphanet:2728)
Blepharophimosis-intellectual deficit syndrome, Verloes type (Orphanet:293725)
CATARACTS, CONGENITAL, WITH SENSORINEURAL DEAFNESS, DOWN SYNDROME-LIKEFACIAL APPEARANCE, SHORT STATURE, AND MENTAL RETARDATION (OMIM:601088)
CHARGE syndrome (Orphanet:138)
CHROMOSOME 1p32-p31 DELETION SYNDROME (OMIM:613735)
COLD-INDUCED SWEATING SYNDROME 1 (OMIM:272430)
COWDEN SYNDROME 5 (OMIM:615108)
COWDEN SYNDROME 6 (OMIM:615109)
Camptodactyly - joint contractures - facial skeletal defects (Orphanet:1323)
Camptodactyly syndrome, Guadalajara type 1 (Orphanet:1327)
Carney complex-trismus-pseudocamptodactyly syndrome (Orphanet:319340)
Charlie M syndrome (Orphanet:1406)
Choanal atresia - deafness - cardiac defects - dysmorphism (Orphanet:1200)
Chondrodysplasia with joint dislocations, gPAPP type (Orphanet:280586)
Cleft palate-lateral synechia syndrome (Orphanet:2016)
Cold-induced sweating syndrome (Orphanet:157820)
Congenital nephrotic syndrome-interstitial lung disease-epidermolysis bullosa syndrome (Orphanet:306504)
Cowden syndrome (Orphanet:201)
Craniofacial-deafness-hand syndrome (Orphanet:1529)
Craniomicromelic syndrome (Orphanet:1524)
Cutis gyrata - acanthosis nigricans - craniosynostosis (Orphanet:1555)
Cutis laxa (Orphanet:209)
DESBUQUOIS DYSPLASIA 1 (OMIM:251450)
De Barsy syndrome (Orphanet:2962)
Desbuquois syndrome (Orphanet:1425)
Desmosterolosis (Orphanet:35107)
Digitotalar dysmorphism (Orphanet:1146)
Dislocation of the hip - dysmorphism (Orphanet:2412)
Distal 22q11.2 microdeletion syndrome (Orphanet:261330)
Distal limb deficiencies - micrognathia syndrome (Orphanet:1307)
Distal monosomy 17q (Orphanet:1597)
Distal trisomy 6p (Orphanet:1745)
Down syndrome (Orphanet:870)
Dysmorphism - multiple structural anomalies (Orphanet:1780)
Dyssegmental dysplasia, Silverman-Handmaker type (Orphanet:1865)
EHLERS-DANLOS SYNDROME, PROGEROID TYPE, 1 (OMIM:130070)
Ear-patella-short stature syndrome (Orphanet:2554)
Edinburgh malformation syndrome (Orphanet:1895)
Ehlers-Danlos syndrome, musculocontractural type (Orphanet:2953)
Ehlers-Danlos syndrome, progeroid type (Orphanet:75496)
FACIAL DYSMORPHISM WITH MULTIPLE MALFORMATIONS (OMIM:227255)
FETAL AKINESIA DEFORMATION SEQUENCE (OMIM:208150)
FIBROCHONDROGENESIS 1 (OMIM:228520)
FRONTOOCULAR SYNDROME (OMIM:605321)
Faciocardiorenal syndrome (Orphanet:1973)
Fetal Gaucher disease (Orphanet:85212)
Fetal akinesia deformation sequence (Orphanet:994)
Fetal valproate syndrome (Orphanet:1906)
Fibrochondrogenesis (Orphanet:2021)
Fine-Lubinsky syndrome (Orphanet:1272)
Flat face - microstomia - ear anomaly (Orphanet:1968)
Freeman-Sheldon syndrome (Orphanet:2053)
HENNEKAM LYMPHANGIECTASIA-LYMPHEDEMA SYNDROME 2 (OMIM:616006)
Hallermann-Streiff syndrome (Orphanet:2108)
Hamel cerebro-palato-cardiac syndrome (Orphanet:93946)
Harrod syndrome (Orphanet:2115)
Heart defect - round face - congenital developmental delay (Orphanet:1355)
Hennekam syndrome (Orphanet:2136)
Holoprosencephaly - postaxial polydactyly (Orphanet:2166)
Hunter-McAlpine craniosynostosis (Orphanet:97340)
Hypertelorism-microtia-facial clefting syndrome (Orphanet:2213)
Hypoglossia - hypodactyly (Orphanet:989)
Hypomandibular faciocranial dysostosis (Orphanet:1790)
Ichthyosis - oral and digital anomalies (Orphanet:2272)
Iniencephaly (Orphanet:63259)
Intellectual deficit - hypoplastic corpus callosum - preauricular tag (Orphanet:1495)
Intellectual deficit, X-linked, Brooks type (Orphanet:3056)
Intellectual deficit, X-linked, Pai type (Orphanet:85322)
Isolated congenital hypoglossia/aglossia (Orphanet:141152)
KBG syndrome (Orphanet:2332)
KNIEST-LIKE DYSPLASIA WITH PURSED LIPS AND ECTOPIA LENTIS (OMIM:245160)
LAMBOTTE SYNDROME (OMIM:245552)
LUBS X-LINKED MENTAL RETARDATION SYNDROME (OMIM:300260)
Larsen-like osseous dysplasia - short stature (Orphanet:2370)
Larsen-like syndrome, B3GAT3 type (Orphanet:284139)
Lethal Kniest-like dysplasia (Orphanet:2347)
Lethal Larsen-like syndrome (Orphanet:2371)
Lethal faciocardiomelic dysplasia (Orphanet:1972)
Lethal hemolytic anemia - genital anomalies (Orphanet:1046)
Lethal multiple pterygium syndrome (Orphanet:33108)
Lethal osteosclerotic bone dysplasia (Orphanet:1832)
Lethal restrictive dermopathy (Orphanet:1662)
Lhermitte-Duclos disease (Orphanet:65285)
Lipodystrophy due to peptidic growth factors deficiency (Orphanet:1979)
MEIER-GORLIN SYNDROME 1 (OMIM:224690)
MEIER-GORLIN SYNDROME 2 (OMIM:613800)
MEIER-GORLIN SYNDROME 3 (OMIM:613803)
MEIER-GORLIN SYNDROME 4 (OMIM:613804)
MENTAL RETARDATION, AUTOSOMAL DOMINANT 26 (OMIM:615834)
MIDFACE HYPOPLASIA, OBESITY, DEVELOPMENTAL DELAY, AND NEONATAL HYPOTONIA (OMIM:608624)
MYELODYSPLASIA, IMMUNODEFICIENCY, FACIAL DYSMORPHISM, SHORT STATURE,AND PSYCHOMOTOR DELAY (OMIM:601347)
MYOPATHY, CENTRONUCLEAR, 5 (OMIM:615959)
Malignant hyperthermia - arthrogryposis - torticollis (Orphanet:2215)
Mandibular hypoplasia-deafness-progeroid syndrome (Orphanet:363649)
Mandibuloacral dysplasia (Orphanet:2457)
Mandibuloacral dysplasia with type B lipodystrophy (Orphanet:90154)
Marden-Walker syndrome (Orphanet:2461)
Marfanoid habitus - intellectual deficit, autosomal recessive (Orphanet:2463)
Megalencephaly - polymicrogyria - postaxial polydactyly - hydrocephalus (Orphanet:83473)
Mesomelia-synostoses syndrome (Orphanet:2496)
Microcephaly-microcornea syndrome, Seemanova type (Orphanet:2528)
Monosomy 9p (Orphanet:261112)
Monosomy 9q22.3 (Orphanet:77301)
Multiple congenital anomalies-hypotonia-seizures syndrome type 2 (Orphanet:300496)
Multiple epiphyseal dysplasia, Beighton type (Orphanet:166011)
Myhre syndrome (Orphanet:2588)
Neuralgic amyotrophy (Orphanet:2901)
Non-progressive cerebellar ataxia with intellectual deficit (Orphanet:314647)
OCULODENTODIGITAL DYSPLASIA, AUTOSOMAL RECESSIVE (OMIM:257850)
OSTEOGENESIS IMPERFECTA, TYPE XII (OMIM:613849)
Oculocerebral hypopigmentation syndrome, Cross type (Orphanet:2719)
Osteocraniostenosis (Orphanet:2763)
Otopalatodigital syndrome (Orphanet:669)
Otopalatodigital syndrome type 1 (Orphanet:90650)
Otopalatodigital syndrome type 2 (Orphanet:90652)
PROGEROID FACIAL APPEARANCE WITH HAND ANOMALIES (OMIM:602249)
Proteus-like syndrome (Orphanet:2969)
RAPP-HODGKIN SYNDROME (OMIM:129400)
Recessive dystrophic epidermolysis bullosa inversa (Orphanet:79409)
Recessive dystrophic epidermolysis bullosa-generalized other (Orphanet:89842)
Renpenning syndrome (Orphanet:3242)
Richieri Costa-Pereira syndrome (Orphanet:3102)
Rubinstein-Taybi syndrome due to CREBBP mutations (Orphanet:353277)
Ruvalcaba syndrome (Orphanet:3121)
SHORT STATURE, AUDITORY CANAL ATRESIA, MANDIBULAR HYPOPLASIA, ANDSKELETAL ABNORMALITIES (OMIM:602471)
SIMOSA CRANIOFACIAL SYNDROME (OMIM:182150)
SKELETAL DEFECTS, GENITAL HYPOPLASIA, AND MENTAL RETARDATION (OMIM:612447)
STEVENSON-CAREY SYNDROME (OMIM:611961)
Schilbach-Rott syndrome (Orphanet:2353)
Schwartz-Jampel syndrome (Orphanet:800)
Scleroderma (Orphanet:801)
Severe generalized recessive dystrophic epidermolysis bullosa (Orphanet:79408)
Sheldon-Hall syndrome (Orphanet:1147)
Short stature - craniofacial anomalies - genital hypoplasia (Orphanet:2994)
Subaortic stenosis - short stature (Orphanet:3191)
Syndromic diarrhea (Orphanet:84064)
Syngnathia multiple anomalies (Orphanet:3262)
Teebi-Shaltout syndrome (Orphanet:3291)
Tel Hashomer camptodactyly syndrome (Orphanet:3292)
Tetraamelia - multiple malformations (Orphanet:3301)
Tetrasomy 18p (Orphanet:3307)
Treacher-Collins syndrome (Orphanet:861)
Triploidy (Orphanet:3376)
Trisomy 17p (Orphanet:261290)
Trisomy 18 (Orphanet:3380)
Trisomy 1q (Orphanet:261344)
Ulbright-Hodes syndrome (Orphanet:3404)
Van Regemorter-Pierquin-Vamos syndrome (Orphanet:3419)
WARBURG MICRO SYNDROME 4 (OMIM:615663)
WHISTLING FACE SYNDROME, RECESSIVE FORM (OMIM:277720)
Weaver-Williams syndrome (Orphanet:3448)
Wiedemann-Rautenstrauch syndrome (Orphanet:3455)
Wilson-Turner syndrome (Orphanet:3459)
XK aprosencephaly (Orphanet:3469)