Flexion contracture
Symptom Information:
Symptom ID: | HPO:0001371 | ||||||||||||||||||||||||||||||||||||||||||||||||||||
Synonyms: |
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Quality: | |||||||||||||||||||||||||||||||||||||||||||||||||||||
Cross references: |
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Is a (Direct Parents): |
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Is a (Whole tree): |
HPO:
All(HPO:0000001) Phenotypic abnormality(HPO:0000118) Abnormality of the musculature(HPO:0003011) Abnormality of muscle morphology(HPO:0011805) Flexion contracture(HPO:0001371) Abnormality of the skeletal system(HPO:0000924) Abnormality of skeletal morphology(HPO:0011842) Abnormal joint morphology(HPO:0001367) Abnormality of joint mobility(HPO:0011729) Flexion contracture(HPO:0001371) Abnormality of connective tissue(HPO:0003549) Flexion contracture(HPO:0001371) MedDRA: |
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Database Frequency: | 220 / 7739 | ||||||||||||||||||||||||||||||||||||||||||||||||||||
Resource: |
All diseases associated with this symptom:
1p36 deletion syndrome | (Orphanet:1606) |
8q22.1 microdeletion syndrome | (Orphanet:178303) |
ALG1-CDG | (Orphanet:79327) |
ALG13-CDG | (Orphanet:324422) |
ALG3-CDG | (Orphanet:79321) |
ANE syndrome | (Orphanet:157954) |
ATAXIA-TELANGIECTASIA-LIKE DISORDER 2 | (OMIM:615919) |
Aarskog-Scott syndrome | (Orphanet:915) |
Aase-Smith syndrome | (Orphanet:916) |
Absence of fingerprints - congenital milia | (Orphanet:1658) |
Acromesomelic dysplasia, Grebe type | (Orphanet:2098) |
Allan-Herndon-Dudley syndrome | (Orphanet:59) |
Alopecia - contractures - dwarfism - intellectual deficit | (Orphanet:1005) |
Amish lethal microcephaly | (Orphanet:99742) |
Antley-Bixler syndrome | (Orphanet:83) |
Arterial tortuosity syndrome | (Orphanet:3342) |
Arthrogryposis - renal dysfunction - cholestasis | (Orphanet:2697) |
Autism spectrum disorder-epilepsy-arthrogryposis syndrome | (Orphanet:370943) |
Autosomal dominant Charcot-Marie-Tooth disease type 2A2 | (Orphanet:99947) |
Autosomal dominant Charcot-Marie-Tooth disease type 2E | (Orphanet:99939) |
Autosomal dominant centronuclear myopathy | (Orphanet:169189) |
Autosomal dominant limb-girdle muscular dystrophy type 1B | (Orphanet:264) |
Autosomal dominant limb-girdle muscular dystrophy type 1F | (Orphanet:55595) |
Autosomal recessive Charcot-Marie-Tooth disease with hoarseness | (Orphanet:101097) |
Autosomal recessive centronuclear myopathy | (Orphanet:169186) |
Autosomal recessive limb girdle muscular dystrophy type 2A | (Orphanet:267) |
Autosomal recessive limb-girdle muscular dystrophy type 2C | (Orphanet:353) |
Autosomal recessive limb-girdle muscular dystrophy type 2D | (Orphanet:62) |
Autosomal recessive limb-girdle muscular dystrophy type 2G | (Orphanet:34514) |
Autosomal recessive limb-girdle muscular dystrophy type 2K | (Orphanet:86812) |
Autosomal recessive limb-girdle muscular dystrophy type 2M | (Orphanet:206554) |
Autosomal recessive limb-girdle muscular dystrophy type 2Q | (Orphanet:254361) |
Autosomal recessive multiple pterygium syndrome | (Orphanet:2990) |
Autosomal recessive spastic paraplegia type 11 | (Orphanet:2822) |
Autosomal recessive spastic paraplegia type 20 | (Orphanet:101000) |
Autosomal recessive spastic paraplegia type 45 | (Orphanet:320396) |
BRACHYPHALANGY, POLYDACTYLY, AND TIBIAL APLASIA/HYPOPLASIA | (OMIM:609945) |
BRUCK SYNDROME 2 | (OMIM:609220) |
Bathing suit ichthyosis | (Orphanet:100976) |
Bethlem myopathy | (Orphanet:610) |
Blau syndrome | (Orphanet:90340) |
Bohring-Opitz syndrome | (Orphanet:97297) |
Buschke-Ollendorff syndrome | (Orphanet:1306) |
CAMOS syndrome | (Orphanet:83472) |
CANDLE syndrome | (Orphanet:325004) |
CATARACTS, GROWTH HORMONE DEFICIENCY, SENSORY NEUROPATHY, SENSORINEURALHEARING LOSS, AND SKELETAL DYSPLASIA | (OMIM:616007) |
CEREBRAL PALSY, SPASTIC QUADRIPLEGIC, 1 | (OMIM:603513) |
CEREBROOCULOFACIOSKELETAL SYNDROME 4 | (OMIM:610758) |
CHARCOT-MARIE-TOOTH DISEASE, AXONAL, WITH VOCAL CORD PARESIS, AUTOSOMALRECESSIVE | (OMIM:607706) |
CHARCOT-MARIE-TOOTH DISEASE, GUADALAJARA NEURONAL TYPE | (OMIM:118230) |
CHILD syndrome | (Orphanet:139) |
CLN1 disease | (Orphanet:228329) |
COCKAYNE SYNDROME, TYPE III | (OMIM:216411) |
Cap myopathy | (Orphanet:171881) |
Central core disease | (Orphanet:597) |
Cerebro-costo-mandibular syndrome | (Orphanet:1393) |
Christianson syndrome | (Orphanet:85278) |
Classic multiminicore myopathy | (Orphanet:324604) |
Congenital brain dysgenesis due to glutamine synthetase deficiency | (Orphanet:71278) |
Congenital ichthyosis - intellectual deficit - spastic quadriplegia | (Orphanet:352333) |
Congenital lethal myopathy, Compton-North type | (Orphanet:210163) |
Congenital muscular dystrophy due to LMNA mutation | (Orphanet:157973) |
Congenital muscular dystrophy type 1A | (Orphanet:258) |
Congenital muscular dystrophy, Ullrich type | (Orphanet:75840) |
Congenital myopathy with excess of thin filaments | (Orphanet:98904) |
Connective tissue disorder due to lysyl hydroxylase-3 deficiency | (Orphanet:300284) |
Corpus callosum agenesis - neuronopathy | (Orphanet:1496) |
Czech dysplasia, metatarsal type | (Orphanet:137678) |
DPAGT1-CDG | (Orphanet:86309) |
Dermatoosteolysis, Kirghizian type | (Orphanet:1657) |
Desmin-related myopathy with Mallory body-like inclusions | (Orphanet:84132) |
Diffuse cutaneous systemic sclerosis | (Orphanet:220393) |
Duchenne muscular dystrophy | (Orphanet:98896) |
Epidermolysis bullosa simplex with pyloric atresia | (Orphanet:158684) |
Fatal infantile hypertonic myofibrillar myopathy | (Orphanet:280553) |
Fetal Gaucher disease | (Orphanet:85212) |
Fetal akinesia-cerebral and retinal hemorrhage syndrome | (Orphanet:363409) |
Fowler syndrome | (Orphanet:221126) |
Fucosidosis | (Orphanet:349) |
Galloway-Mowat syndrome | (Orphanet:2065) |
Gaucher disease | (Orphanet:355) |
Gaucher disease type 2 | (Orphanet:77260) |
Generalized congenital lipodystrophy with myopathy | (Orphanet:228429) |
Glycogen storage disease due to glycogen branching enzyme deficiency | (Orphanet:367) |
Hereditary sensory and autonomic neuropathy type 6 | (Orphanet:314381) |
Huntington disease-like 3 | (Orphanet:157946) |
Hurler syndrome | (Orphanet:93473) |
Hypotonia-cerebral atrophy-hyperglycinemia syndrome | (Orphanet:363424) |
Inherited congenital spastic tetraplegia | (Orphanet:210141) |
Intellectual deficit - cataracts - calcified pinnae - myopathy | (Orphanet:3042) |
Intellectual deficit, X-linked - Dandy-Walker malformation - basal ganglia disease - Seizures | (Orphanet:1568) |
Intellectual deficit, X-linked, Brooks type | (Orphanet:3056) |
Intellectual disability-developmental delay-contractures syndrome | (Orphanet:3454) |
Isolated succinate-CoQ reductase deficiency | (Orphanet:3208) |
JMP syndrome | (Orphanet:324999) |
Jacobsen syndrome | (Orphanet:2308) |
Junctional epidermolysis bullosa - pyloric atresia | (Orphanet:79403) |
KAGAMI-OGATA SYNDROME | (OMIM:608149) |
KAHRIZI SYNDROME | (OMIM:612713) |
KEPPEN-LUBINSKY SYNDROME | (OMIM:614098) |
KNIEST-LIKE DYSPLASIA WITH PURSED LIPS AND ECTOPIA LENTIS | (OMIM:245160) |
LUJAN-FRYNS SYNDROME | (OMIM:309520) |
Lethal multiple pterygium syndrome | (Orphanet:33108) |
Lethal osteosclerotic bone dysplasia | (Orphanet:1832) |
Lethal restrictive dermopathy | (Orphanet:1662) |
Leukoencephalopathy with brain stem and spinal cord involvement - lactate elevation | (Orphanet:137898) |
Limited cutaneous systemic sclerosis | (Orphanet:220402) |
Lipodystrophy due to peptidic growth factors deficiency | (Orphanet:1979) |
MEIER-GORLIN SYNDROME 1 | (OMIM:224690) |
MELAS | (Orphanet:550) |
MENTAL RETARDATION, AUTOSOMAL DOMINANT 9 | (OMIM:614255) |
MICROCEPHALIC OSTEODYSPLASTIC PRIMORDIAL DWARFISM, TYPE I | (OMIM:210710) |
MPDU1-CDG | (Orphanet:79323) |
MULTICENTRIC OSTEOLYSIS, NODULOSIS, AND ARTHROPATHY | (OMIM:259600) |
MUSCULAR DYSTROPHY, CONGENITAL, MEROSIN-POSITIVE | (OMIM:609456) |
MUSCULAR DYSTROPHY-DYSTROGLYCANOPATHY (CONGENITAL WITH BRAIN AND EYEANOMALIES), TYPE A, 12 | (OMIM:615249) |
MUSCULAR DYSTROPHY-DYSTROGLYCANOPATHY (CONGENITAL WITH BRAIN AND EYEANOMALIES), TYPE A, 4 | (OMIM:253800) |
MUSCULAR DYSTROPHY-DYSTROGLYCANOPATHY (CONGENITAL WITH BRAIN AND EYEANOMALIES), TYPE A, 6 | (OMIM:613154) |
MUSCULAR DYSTROPHY-DYSTROGLYCANOPATHY (CONGENITAL WITH MENTAL RETARDATION),TYPE B, 1 | (OMIM:613155) |
MUSCULAR DYSTROPHY-DYSTROGLYCANOPATHY (CONGENITAL WITH MENTAL RETARDATION),TYPE B, 14 | (OMIM:615351) |
MUSCULAR DYSTROPHY-DYSTROGLYCANOPATHY (CONGENITAL WITH MENTAL RETARDATION),TYPE B, 2 | (OMIM:613156) |
MYASTHENIC SYNDROME, CONGENITAL, 14 | (OMIM:616228) |
MYASTHENIC SYNDROME, CONGENITAL, 18 | (OMIM:616330) |
MYASTHENIC SYNDROME, CONGENITAL, 2A, SLOW-CHANNEL | (OMIM:616313) |
MYOPATHY, AREFLEXIA, RESPIRATORY DISTRESS, AND DYSPHAGIA, EARLY-ONSET | (OMIM:614399) |
MYOPATHY, CENTRONUCLEAR, 1 | (OMIM:160150) |
MYOPATHY, CONGENITAL, WITH FIBER-TYPE DISPROPORTION | (OMIM:255310) |
MYOPATHY, REDUCING BODY, X-LINKED, CHILDHOOD-ONSET | (OMIM:300718) |
MYOPATHY, REDUCING BODY, X-LINKED, EARLY-ONSET, SEVERE | (OMIM:300717) |
MYOPATHY, TUBULAR AGGREGATE, 2 | (OMIM:615883) |
Mandibular hypoplasia-deafness-progeroid syndrome | (Orphanet:363649) |
Mandibuloacral dysplasia | (Orphanet:2457) |
Mandibuloacral dysplasia with type A lipodystrophy | (Orphanet:90153) |
Mandibuloacral dysplasia with type B lipodystrophy | (Orphanet:90154) |
Marfan syndrome type 1 | (Orphanet:284963) |
Marinesco-Sjögren syndrome | (Orphanet:559) |
Metatropic dysplasia | (Orphanet:2635) |
Micrencephaly - corpus callosum agenesis - abnormal genitalia | (Orphanet:2508) |
Microcephalic primordial dwarfism due to ZNF335 deficiency | (Orphanet:329228) |
Mitochondrial encephalo-cardio-myopathy due to TMEM70 deficiency | (Orphanet:1194) |
Moderate multiminicore disease with hand involvement | (Orphanet:178145) |
Moebius syndrome | (Orphanet:570) |
Mucopolysaccharidosis type 1 | (Orphanet:579) |
Mucopolysaccharidosis type 2 | (Orphanet:580) |
Mucopolysaccharidosis type 7 | (Orphanet:584) |
Multiple congenital anomalies-hypotonia-seizures syndrome type 2 | (Orphanet:300496) |
Multiple epiphyseal dysplasia, Lowry type | (Orphanet:166016) |
Mutilating palmoplantar keratoderma with periorificial keratotic plaques | (Orphanet:659) |
NEMALINE MYOPATHY 1 | (OMIM:609284) |
NEMALINE MYOPATHY 2 | (OMIM:256030) |
NEMALINE MYOPATHY 4 | (OMIM:609285) |
NEMALINE MYOPATHY 8 | (OMIM:615348) |
NEUROPATHY, CONGENITAL, WITH ARTHROGRYPOSIS MULTIPLEX | (OMIM:162370) |
Nakajo-Nishimura syndrome | (Orphanet:2615) |
Native American myopathy | (Orphanet:168572) |
Nestor-Guillermo progeria syndrome | (Orphanet:280576) |
Neu-Laxova syndrome | (Orphanet:2671) |
OPITZ-KAVEGGIA SYNDROME | (OMIM:305450) |
Oculofaciocardiodental syndrome | (Orphanet:2712) |
Osteopathia striata - cranial sclerosis | (Orphanet:2780) |
Otospondylomegaepiphyseal dysplasia | (Orphanet:1427) |
PMM2-CDG | (Orphanet:79318) |
PONTOCEREBELLAR HYPOPLASIA, TYPE 1B | (OMIM:614678) |
PONTOCEREBELLAR HYPOPLASIA, TYPE 1C | (OMIM:616081) |
PONTOCEREBELLAR HYPOPLASIA, TYPE 2D | (OMIM:613811) |
PONTOCEREBELLAR HYPOPLASIA, TYPE 2E | (OMIM:615851) |
Parastremmatic dwarfism | (Orphanet:2646) |
Partington syndrome | (Orphanet:94083) |
Pelizaeus-Merzbacher-like due to HSPD1 mutation | (Orphanet:280288) |
Permanent neonatal diabetes mellitus - pancreatic and cerebellar agenesis | (Orphanet:65288) |
Pontocerebellar hypoplasia type 8 | (Orphanet:324569) |
Proteasome disability syndrome | (Orphanet:324977) |
Pyruvate dehydrogenase lipoic acid synthetase deficiency | (OMIM:614462) |
RIGIDITY AND MULTIFOCAL SEIZURE SYNDROME, LETHAL NEONATAL | (OMIM:614498) |
Recessive dystrophic epidermolysis bullosa inversa | (Orphanet:79409) |
Recombinant 8 syndrome | (Orphanet:96167) |
Reducing body myopathy | (Orphanet:97239) |
Rhizomelic chondrodysplasia punctata | (Orphanet:177) |
Rhizomelic chondrodysplasia punctata type 1 | (Orphanet:309789) |
Rhizomelic chondrodysplasia punctata type 2 | (Orphanet:309796) |
Rigid spine syndrome | (Orphanet:97244) |
Rubinstein-Taybi syndrome due to CREBBP mutations | (Orphanet:353277) |
Rudiger syndrome | (Orphanet:3118) |
SCAPULOPERONEAL MYOPATHY, X-LINKED DOMINANT | (OMIM:300695) |
SCHAAF-YANG SYNDROME | (OMIM:615547) |
SHORT STATURE, AUDITORY CANAL ATRESIA, MANDIBULAR HYPOPLASIA, ANDSKELETAL ABNORMALITIES | (OMIM:602471) |
SPASTIC PARAPLEGIA 51, AUTOSOMAL RECESSIVE | (OMIM:613744) |
SPASTIC PARAPLEGIA 52, AUTOSOMAL RECESSIVE | (OMIM:614067) |
SPINOCEREBELLAR ATAXIA, AUTOSOMAL RECESSIVE 18 | (OMIM:616204) |
STEVENSON-CAREY SYNDROME | (OMIM:611961) |
STIFF SKIN SYNDROME | (OMIM:184900) |
Sanfilippo syndrome type D | (Orphanet:79272) |
Say-Barber-Miller syndrome | (Orphanet:3132) |
Severe generalized recessive dystrophic epidermolysis bullosa | (Orphanet:79408) |
Sheldon-Hall syndrome | (Orphanet:1147) |
Short chain acyl-CoA dehydrogenase deficiency | (Orphanet:26792) |
Shprintzen-Goldberg syndrome | (Orphanet:2462) |
Spastic paraplegia type 2 | (Orphanet:99015) |
Spastic paraplegia-optic atrophy-neuropathy syndrome | (Orphanet:320406) |
Spondylo-megaepiphyseal-metaphyseal dysplasia | (Orphanet:228387) |
Spondyloepimetaphyseal dysplasia with joint laxity | (Orphanet:93359) |
Spondyloepimetaphyseal dysplasia, Bieganski type | (Orphanet:168448) |
Spondyloepiphyseal dysplasia, Cantu type | (Orphanet:163654) |
Stiff skin syndrome | (Orphanet:2833) |
TEMPLE SYNDROME | (OMIM:616222) |
TRICHOTHIODYSTROPHY, PHOTOSENSITIVE | (OMIM:601675) |
Tetrasomy 12p | (Orphanet:884) |
Tubular aggregate myopathy | (Orphanet:2593) |
Van den Ende-Gupta syndrome | (Orphanet:2460) |
WARBURG MICRO SYNDROME 2 | (OMIM:614225) |
WARBURG MICRO SYNDROME 3 | (OMIM:614222) |
WARBURG MICRO SYNDROME 4 | (OMIM:615663) |
WHISTLING FACE SYNDROME, RECESSIVE FORM | (OMIM:277720) |
Wiedemann-Rautenstrauch syndrome | (Orphanet:3455) |
Williams syndrome | (Orphanet:904) |
X-linked centronuclear myopathy | (Orphanet:596) |
X-linked lethal multiple pterygium syndrome | (Orphanet:79447) |
X-linked myopathy with postural muscle atrophy | (Orphanet:178461) |
Xeroderma pigmentosum complementation group F | (Orphanet:276264) |
Zellweger-like syndrome without peroxisomal anomalies | (Orphanet:50812) |