Reduced tendon reflexes

Symptom Information:

Symptom ID: HPO:0001315
Synonyms:
Absent or decreased deep tendon reflexes [HPO:0001315]
Decreased to absent deep tendon reflexes [HPO:0001315]
Decreased/absent deep tendon reflexes [HPO:0001315]
Diminished or absent deep tendon reflexes [HPO:0001315]
Diminished or absent tendon reflexes [HPO:0001315]
Hypoactive to absent deep tendon reflexes [HPO:0001315]
Impaired tendon reflexes [HPO:0001315]
Reduced/absent deep tendon reflexes [HPO:0001315]
Weak or absent deep tendon reflexes [HPO:0001315]
Hyporeflexia [Orphanet:43350]
Absent reflex (finding) [Orphanet:43350]
Hyporeflexia (finding) [Orphanet:43350]
Absent reflex [Orphanet:43350]
Absent or decreased deep tendon reflexes [OMIM:Absent or decreased deep tendon reflexes]
Decreased to absent deep tendon reflexes [OMIM:Decreased to absent deep tendon reflexes]
Diminished or absent deep tendon reflexes [OMIM:Diminished or absent deep tendon reflexes]
Diminished or absent tendon reflexes [OMIM:Diminished or absent tendon reflexes]
Reduced/absent deep tendon reflexes [OMIM:Reduced/absent deep tendon reflexes]
Weak or absent deep tendon reflexes [OMIM:Weak or absent deep tendon reflexes]
Areflexia/hyporeflexia [Orphanet:43350]
Areflexia [Orphanet:43350]
Areflexia [MedDRA:10003084]
Absent ankle jerk [MedDRA:10003084]
Absent ankle jerks [MedDRA:10003084]
Absent reflex [MedDRA:10003084]
Absent reflexes [MedDRA:10003084]
PSR/ASR loss [MedDRA:10003084]
Reflex loss [MedDRA:10003084]
Reflexes absent [MedDRA:10003084]
Loss of gag reflex [MedDRA:10003084]
Patellar tendon reflex absent [MedDRA:10003084]
Tendon reflex absent [MedDRA:10003084]
Cremasteric reflex absent [MedDRA:10003084]
Hyporeflexia [MedDRA:10021089]
Achilles tendon reflex decreased [MedDRA:10021089]
Diminished reflexes [MedDRA:10021089]
Lower extremities deep decreased reflex test [MedDRA:10021089]
Patellar tendon reflex decreased [MedDRA:10021089]
Reflexes decreased [MedDRA:10021089]
Reflexes tendon decreased absent [MedDRA:10021089]
Tendon reflex decreased [MedDRA:10021089]
Retching reflex decreased [MedDRA:10021089]
Poor swallowing reflex [MedDRA:10021089]
Absent ankle jerks [OMIM:Absent ankle jerks]
Absent reflexes [OMIM:Absent reflexes]
Areflexia (30%) [OMIM:Areflexia (30%)]
Areflexia (common) [OMIM:Areflexia (common)]
Areflexia (in some patients) [OMIM:Areflexia (in some patients)]
Areflexia (in some) [OMIM:Areflexia (in some)]
Decrease/absent deep tendon reflexes [OMIM:Decrease/absent deep tendon reflexes]
Hyporeflexia (90%) [OMIM:Hyporeflexia (90%)]
Hyporeflexia (early) [OMIM:Hyporeflexia (early)]
Hyporeflexia (in some patients) [OMIM:Hyporeflexia (in some patients)]
Hyporeflexia (in some) [OMIM:Hyporeflexia (in some)]
Hyporeflexia (later in disease course) [OMIM:Hyporeflexia (later in disease course)]
Hyporeflexia (less common) [OMIM:Hyporeflexia (less common)]
Hyporeflexia (occurs later) [OMIM:Hyporeflexia (occurs later)]
Hyporeflexia (rare) [OMIM:Hyporeflexia (rare)]
Hyporeflexia/areflexia [OMIM:Hyporeflexia/areflexia]
Quality:
Cross references:
HPO:0001265 "Hyporeflexia" [Orphanet:43350]
HPO:0001284 "Areflexia" [Orphanet:43350]
Orphanet:43350 "Areflexia/hyporeflexia" [Orphanet:43350]
OMIM: "Absent or decreased deep tendon reflexes" [OMIM:Absent or decreased deep tendon reflexes]
OMIM: "Decreased to absent deep tendon reflexes" [OMIM:Decreased to absent deep tendon reflexes]
OMIM: "Diminished or absent deep tendon reflexes" [OMIM:Diminished or absent deep tendon reflexes]
OMIM: "Diminished or absent tendon reflexes" [OMIM:Diminished or absent tendon reflexes]
OMIM: "Reduced/absent deep tendon reflexes" [OMIM:Reduced/absent deep tendon reflexes]
OMIM: "Weak or absent deep tendon reflexes" [OMIM:Weak or absent deep tendon reflexes]
OMIM: "Absent ankle jerks" [OMIM:Absent ankle jerks]
OMIM: "Absent reflexes" [OMIM:Absent reflexes]
OMIM: "Areflexia (30%)" [OMIM:Areflexia (30%)]
OMIM: "Areflexia (common)" [OMIM:Areflexia (common)]
OMIM: "Areflexia (in some patients)" [OMIM:Areflexia (in some patients)]
OMIM: "Areflexia (in some)" [OMIM:Areflexia (in some)]
OMIM: "Decrease/absent deep tendon reflexes" [OMIM:Decrease/absent deep tendon reflexes]
OMIM: "Hyporeflexia (90%)" [OMIM:Hyporeflexia (90%)]
OMIM: "Hyporeflexia (early)" [OMIM:Hyporeflexia (early)]
OMIM: "Hyporeflexia (in some patients)" [OMIM:Hyporeflexia (in some patients)]
OMIM: "Hyporeflexia (in some)" [OMIM:Hyporeflexia (in some)]
OMIM: "Hyporeflexia (later in disease course)" [OMIM:Hyporeflexia (later in disease course)]
OMIM: "Hyporeflexia (less common)" [OMIM:Hyporeflexia (less common)]
OMIM: "Hyporeflexia (occurs later)" [OMIM:Hyporeflexia (occurs later)]
OMIM: "Hyporeflexia (rare)" [OMIM:Hyporeflexia (rare)]
OMIM: "Hyporeflexia/areflexia" [OMIM:Hyporeflexia/areflexia]
UMLS:C0151888 "Hyporeflexia" [Orphanet:43350]
UMLS:C0234146 "Absent reflex" [Orphanet:43350]
Is a (Direct Parents):
Orphanet [DEL]Motor deficit/trouble
MedDRA Abnormal reflexes
HPO         Abnormality of nervous system physiology
Is a (Whole tree): HPO:
All(HPO:0000001)
    Phenotypic abnormality(HPO:0000118)
       Abnormality of the nervous system(HPO:0000707)
          Abnormality of nervous system physiology(HPO:0012638)
             Reduced tendon reflexes(HPO:0001315)
MedDRA:
Nervous system disorders(MedDRA:10029205)
    Neurological disorders NEC(MedDRA:10029305)
       Abnormal reflexes(MedDRA:10000171)
          Reduced tendon reflexes(HPO:0001315)
Database Frequency: 160 / 7739
Resource:

All diseases associated with this symptom:

3-methylglutaconic aciduria type 4 (Orphanet:67048)
ATAXIA-TELANGIECTASIA (OMIM:208900)
Abetalipoproteinemia (Orphanet:14)
Adducted thumbs - arthrogryposis, Christian type (Orphanet:2952)
Adult polyglucosan body disease (Orphanet:206583)
Adult-onset multiple mitochondrial DNA deletion syndrome due to DGUOK deficiency (Orphanet:329314)
Arachnoiditis (Orphanet:137817)
Arthrogryposis due to muscular dystrophy (Orphanet:1155)
Arthrogryposis-like syndrome (Orphanet:1149)
Ataxia - photosensitivity - short stature (Orphanet:1184)
Ataxia with vitamin E deficiency (Orphanet:96)
Ataxia-deafness-retardation syndrome (Orphanet:1188)
Ataxia-telangiectasia (Orphanet:100)
Autosomal dominant Emery-Dreifuss muscular dystrophy (Orphanet:98853)
Autosomal dominant cerebellar ataxia (Orphanet:99)
Autosomal dominant limb-girdle muscular dystrophy type 1A (Orphanet:266)
Autosomal dominant optic atrophy plus syndrome (Orphanet:1215)
Autosomal recessive Emery-Dreifuss muscular dystrophy (Orphanet:98855)
Autosomal recessive cerebelloparenchymal disorder type 3 (Orphanet:1170)
Autosomal recessive limb-girdle muscular dystrophy type 2M (Orphanet:206554)
Autosomal recessive spastic ataxia - optic atrophy - dysarthria (Orphanet:254343)
Autosomal recessive spastic paraplegia type 11 (Orphanet:2822)
Autosomal recessive spastic paraplegia type 26 (Orphanet:101006)
Autosomal recessive spastic paraplegia type 43 (Orphanet:320370)
Becker muscular dystrophy (Orphanet:98895)
CARDIONEUROMYOPATHY WITH HYALINE MASSES AND NEMALINE RODS (OMIM:606842)
CEDNIK syndrome (Orphanet:66631)
CHARCOT-MARIE-TOOTH DISEASE WITH PTOSIS AND PARKINSONISM (OMIM:118301)
CHARCOT-MARIE-TOOTH DISEASE, GUADALAJARA NEURONAL TYPE (OMIM:118230)
CHARCOT-MARIE-TOOTH PERONEAL MUSCULAR ATROPHY AND FRIEDREICH ATAXIA,COMBINED (OMIM:302900)
COFS syndrome (Orphanet:1466)
Cardiodysrhythmic potassium-sensitive periodic paralysis (Orphanet:37553)
Carnitine palmitoyl transferase 1A deficiency (Orphanet:156)
Cartilage-hair hypoplasia (Orphanet:175)
Cataract - ataxia - deafness (Orphanet:1368)
Caudal regression sequence (Orphanet:3027)
Centronuclear myopathy (Orphanet:595)
Cerebellar ataxia - areflexia - pes cavus - optic atrophy - sensorineural hearing loss (Orphanet:1171)
Charcot-Marie-Tooth disease (Orphanet:166)
Choreoacanthocytosis (Orphanet:2388)
Chylomicron retention disease (Orphanet:71)
Chédiak-Higashi syndrome (Orphanet:167)
Cogan syndrome (Orphanet:1467)
Combined oxidative phosphorylation defect type 8 (Orphanet:319504)
Congenital fiber-type disproportion myopathy (Orphanet:2020)
Congenital hypothyroidism (Orphanet:442)
Congenital muscular dystrophy type 1A (Orphanet:258)
Cortical dysplasia - focal epilepsy syndrome (Orphanet:163681)
DE SANCTIS-CACCHIONE SYNDROME (OMIM:278800)
DPM3-CDG (Orphanet:263494)
Deafness - small bowel diverticulosis - neuropathy (Orphanet:3217)
Deafness - enamel hypoplasia - nail defects (Orphanet:3220)
Dermatoleukodystrophy (Orphanet:1659)
Early-onset X-linked optic atrophy (Orphanet:98890)
Emery-Dreifuss muscular dystrophy (Orphanet:261)
Erythrokeratodermia - ataxia (Orphanet:1955)
FRIEDREICH ATAXIA AND CONGENITAL GLAUCOMA (OMIM:229310)
Familial dysautonomia (Orphanet:1764)
Familial symmetric lipomatosis (Orphanet:2398)
Fragile X-associated tremor/ataxia syndrome (Orphanet:93256)
Friedreich ataxia 1 (OMIM:229300)
Friedreich ataxia 2 (OMIM:601992)
Glycogen storage disease due to acid maltase deficiency (Orphanet:365)
Glycogen storage disease due to glycogen branching enzyme deficiency (Orphanet:367)
Glycogen storage disease due to glycogen branching enzyme deficiency, adult neuromuscular form (Orphanet:308712)
Glycogen storage disease due to glycogen branching enzyme deficiency, childhood combined hepatic and myopathic form (Orphanet:308684)
Glycogen storage disease due to glycogen branching enzyme deficiency, childhood neuromuscular form (Orphanet:308698)
Glycogen storage disease due to glycogen branching enzyme deficiency, congenital neuromuscular form (Orphanet:308670)
Glycogen storage disease due to glycogen branching enzyme deficiency, fatal perinatal neuromuscular form (Orphanet:308655)
Glycogen storage disease due to glycogen branching enzyme deficiency, non progressive hepatic form (Orphanet:308638)
Glycogen storage disease due to glycogen branching enzyme deficiency, progressive hepatic form (Orphanet:308621)
Griscelli disease (Orphanet:381)
Grubben-de Cock-Borghgraef syndrome (Orphanet:2101)
HYPOBETALIPOPROTEINEMIA, FAMILIAL, 1 (OMIM:615558)
Hemihypertrophy (Orphanet:2128)
Hennekam-Beemer syndrome (Orphanet:2135)
Hereditary neuropathy with liability to pressure palsies (Orphanet:640)
Hoyeraal-Hreidarsson syndrome (Orphanet:3322)
Hyperkalemic periodic paralysis (Orphanet:682)
Hypocomplementemic urticarial vasculitis (Orphanet:36412)
Hypomyelination neuropathy - arthrogryposis (Orphanet:2680)
Ichthyosis - hepatosplenomegaly - cerebellar degeneration (Orphanet:2274)
Inclusion body myositis (Orphanet:611)
Infant botulism (Orphanet:178478)
Infantile axonal neuropathy (Orphanet:2679)
Infantile onset spinocerebellar ataxia (Orphanet:1186)
Intellectual deficit, X-linked, Stevenson type (Orphanet:85325)
Isolated glycerol kinase deficiency (Orphanet:408)
Isotretinoin syndrome (Orphanet:2305)
KID syndrome (Orphanet:477)
Kearns-Sayre syndrome (Orphanet:480)
Kennedy disease (Orphanet:481)
Leigh syndrome (Orphanet:506)
Lethal ataxia with deafness and optic atrophy (Orphanet:1187)
Linear nevus sebaceus syndrome (Orphanet:2612)
MELAS (Orphanet:550)
MENTAL RETARDATION, AUTOSOMAL DOMINANT 13 (OMIM:614563)
METACHROMATIC LEUKODYSTROPHY (OMIM:250100)
MITOCHONDRIAL MYOPATHY (OMIM:251900)
MYOGLOBINURIA, ACUTE RECURRENT, AUTOSOMAL RECESSIVE (OMIM:268200)
MYOPATHY, REDUCING BODY, X-LINKED, EARLY-ONSET, SEVERE (OMIM:300717)
Maple syrup urine disease (Orphanet:511)
Marden-Walker syndrome (Orphanet:2461)
Marinesco-Sjögren syndrome (Orphanet:559)
Maternally-inherited Leigh syndrome (Orphanet:255210)
Metachromatic leukodystrophy (Orphanet:512)
Microlissencephaly - micromelia (Orphanet:50810)
Mitochondrial DNA depletion syndrome, encephalomyopathic form with methylmalonic aciduria (Orphanet:1933)
Mitochondrial myopathy with reversible cytochrome C oxidase deficiency (Orphanet:254864)
Mulibrey nanism (Orphanet:2576)
Multifocal muscular fibrosis - obstructed vessels (Orphanet:2033)
Muscular dystrophy - white matter spongiosis (Orphanet:1877)
Myopathy and diabetes mellitus (Orphanet:2596)
Myopathy due to myoadenylate deaminase deficiency (OMIM:615511)
NEURODEGENERATION WITH BRAIN IRON ACCUMULATION 2A (OMIM:256600)
Neuhauser-Eichner-Opitz syndrome (Orphanet:2672)
Neuralgic amyotrophy (Orphanet:2901)
Neurodegeneration with brain iron accumulation due to C19orf12 mutation (Orphanet:289560)
Neutral lipid storage disease (Orphanet:165)
Neutral lipid storage myopathy (Orphanet:98908)
Niemann-Pick disease type A (Orphanet:77292)
Oculocerebrorenal syndrome (Orphanet:534)
Orofaciodigital syndrome type 3 (Orphanet:2752)
POSTERIOR COLUMN ATAXIA (OMIM:176250)
PROGRESSIVE EXTERNAL OPHTHALMOPLEGIA WITH MITOCHONDRIAL DNA DELETIONS,AUTOSOMAL DOMINANT, 5 (OMIM:613077)
Pellagra-like skin rash-neurological manifestations (Orphanet:2837)
Peripheral motor neuropathy - dysautonomia (Orphanet:2400)
Perrault Syndrome 1 (OMIM:233400)
Polymyositis (Orphanet:732)
Polyneuropathy - intellectual deficit - acromicria - premature menopause (Orphanet:2928)
Protein R deficiency (Orphanet:2967)
Proximal spinal muscular atrophy (Orphanet:70)
Psychomotor retardation due to S-adenosylhomocysteine hydrolase deficiency (Orphanet:88618)
Qazi-Markouizos syndrome (Orphanet:3010)
Riboflavin transporter deficiency (Orphanet:97229)
Roussy-Lévy syndrome (Orphanet:3115)
Schwartz-Jampel syndrome (Orphanet:800)
Short stature - heart defect - craniofacial anomalies (Orphanet:1088)
Smith-Magenis syndrome (Orphanet:819)
Spastic paraplegia 64, autosomal recessive (OMIM:615683)
Spinocerebellar ataxia - dysmorphism (Orphanet:1185)
Stoll-Alembik-Finck syndrome (Orphanet:3200)
Stüve-Wiedemann syndrome (Orphanet:3206)
Sudden infant death - dysgenesis of the testes (Orphanet:168593)
Symmetrical thalamic calcifications (Orphanet:1314)
TMCO1 defect syndrome (Orphanet:228407)
Tangier disease (Orphanet:31150)
Tetrasomy 12p (Orphanet:884)
Thoracic dysplasia-hydrocephalus syndrome (Orphanet:1861)
Tyrosinemia type 3 (Orphanet:69723)
Walker-Warburg syndrome (Orphanet:899)
X-linked Charcot-Marie-Tooth disease type 1 (Orphanet:101075)
X-linked Charcot-Marie-Tooth disease type 2 (Orphanet:101076)
X-linked Charcot-Marie-Tooth disease type 4 (Orphanet:101078)
X-linked Charcot-Marie-Tooth disease type 5 (Orphanet:99014)
X-linked Emery-Dreifuss muscular dystrophy (Orphanet:98863)
X-linked centronuclear myopathy (Orphanet:596)
Xeroderma pigmentosum (Orphanet:910)
Zellweger syndrome (Orphanet:912)
Zellweger-like syndrome without peroxisomal anomalies (Orphanet:50812)