POSTERIOR COLUMN ATAXIA

General Information (adopted from Orphanet):

Synonyms, Signs: BIEMOND ATAXIA
Number of Symptoms 12
OrphanetNr:
OMIM Id: 176250
ICD-10:
UMLs:
MeSH:
MedDRA:
Snomed:

Prevalence, inheritance and age of onset:

Prevalence: No data available.
Inheritance: Autosomal dominant inheritance
[Omim]
Age of onset:

Disease classification (adopted from Orphanet):

Parent Diseases: No data available.

Symptom Information: Sort by abundance 

1
 (HPO:0002495) Impaired vibratory sensation 26 / 7739
2
 (HPO:0001251) Ataxia 413 / 7739
3
 (HPO:0010831) Impaired proprioception 7 / 7739
4
 (HPO:0001315) Reduced tendon reflexes 160 / 7739
5
 (HPO:0002650) Scoliosis 705 / 7739
6
 (HPO:0000006) Autosomal dominant inheritance 2518 / 7739
7
 (OMIM) Pain and temperature sensations preserved 1 / 7739
8
 (OMIM) Progressive vibratory and postural sensibility loss 1 / 7739
9
 (OMIM) Muscle stretch reflex losses 1 / 7739
10
 (OMIM) No cerebellar or pyramidal tract involvement 1 / 7739
11
 (OMIM) Flexor plantar responses 2 / 7739
12
 (OMIM) Ataxia due to posterior column degeneration 1 / 7739

Associated genes:

ClinVar (via SNiPA)

Gene symbol Variation Clinical significance Reference

Additional Information: