Infant botulism

General Information (adopted from Orphanet):

Synonyms, Signs: Infant intestinal toxin-mediated botulism
Infantile botulism
Infant intestinal toxemia botulism
Infant intestinal botulism
Number of Symptoms 28
OrphanetNr: 178478
OMIM Id:
ICD-10: A05.1
UMLs: C0238027
MeSH:
MedDRA:
Snomed: 414488002

Prevalence, inheritance and age of onset:

Prevalence: No data available.
Inheritance:
Age of onset: Neonatal
Infancy
[Orphanet]

Disease classification (adopted from Orphanet):

Parent Diseases: Intestinal botulism
 -Rare infectious disease
 -Rare neurologic disease

Symptom Information: Sort by abundance 

1
 (HPO:0000217) Xerostomia Very frequent [Orphanet] 35 / 7739
2
 (HPO:0000298) Mask-like facies Very frequent [Orphanet] 44 / 7739
3
 (HPO:0000600) Abnormality of the pharynx Frequent [Orphanet] 22 / 7739
4
 (HPO:0003781) Excessive salivation Very frequent [Orphanet] 15 / 7739
5
 (HPO:0000615) Abnormality of the pupil Very frequent [Orphanet] 39 / 7739
6
 (HPO:0000508) Ptosis Very frequent [Orphanet] 459 / 7739
7
 (HPO:0000651) Diplopia Very frequent [Orphanet] 37 / 7739
8
 (HPO:0001097) Keratoconjunctivitis sicca Very frequent [Orphanet] 25 / 7739
9
 (HPO:0000389) Chronic otitis media Occasional [Orphanet] 64 / 7739
10
 (HPO:0002360) Sleep disturbance Very frequent [Orphanet] 113 / 7739
11
 (HPO:0011442) Abnormality of central motor function Very frequent [Orphanet] 76 / 7739
12
 (HPO:0006824) Cranial nerve paralysis Very frequent [Orphanet] 81 / 7739
13
 (HPO:0100022) Abnormality of movement Very frequent [Orphanet] 129 / 7739
14
 (HPO:0002015) Dysphagia Very frequent [Orphanet] 301 / 7739
15
 (HPO:0100021) Cerebral palsy Very frequent [Orphanet] 36 / 7739
16
 (HPO:0002167) Neurological speech impairment Very frequent [Orphanet] 308 / 7739
17
 (HPO:0001315) Reduced tendon reflexes Frequent [Orphanet] 160 / 7739
18
 (HPO:0002027) Abdominal pain Occasional [Orphanet] 184 / 7739
19
 (HPO:0002039) Anorexia Very frequent [Orphanet] 62 / 7739
20
 (HPO:0002607) Bowel incontinence Frequent [Orphanet] 33 / 7739
21
 (HPO:0002019) Constipation Very frequent [Orphanet] 194 / 7739
22
 (HPO:0000822) Hypertension Frequent [Orphanet] 224 / 7739
23
 (HPO:0002615) Hypotension Frequent [Orphanet] 52 / 7739
24
 (HPO:0001695) Cardiac arrest Occasional [Orphanet] 87 / 7739
25
 (HPO:0002902) Hyponatremia Occasional [Orphanet] 37 / 7739
26
 (HPO:0002093) Respiratory insufficiency Frequent [Orphanet] 410 / 7739
27
 (HPO:0001608) Abnormality of the voice Very frequent [Orphanet] 126 / 7739
28
 (HPO:0001252) Muscular hypotonia Very frequent [Orphanet] 990 / 7739

Associated genes:

ClinVar (via SNiPA)

Gene symbol Variation Clinical significance Reference

Additional Information: