Intellectual deficit, X-linked, Stevenson type

General Information (adopted from Orphanet):

Synonyms, Signs:
Number of Symptoms 20
OrphanetNr: 85325
OMIM Id:
ICD-10:
UMLs:
MeSH:
MedDRA:
Snomed:

Prevalence, inheritance and age of onset:

Prevalence: 4 cases [Orphanet]
Inheritance: X-linked recessive
[Orphanet]
Age of onset: Childhood
[Orphanet]

Disease classification (adopted from Orphanet):

Parent Diseases: Multiple congenital anomalies/dysmorphic syndrome-intellectual deficit
 -Rare developmental defect during embryogenesis
 -Rare genetic disease
X-linked syndromic intellectual deficit
 -Rare genetic disease
 -Rare neurologic disease

Symptom Information: Sort by abundance 

1
(HPO:0009928) Thick nasal alae Very frequent [Orphanet] 21 / 7739
2
(HPO:0000691) Microdontia Frequent [Orphanet] 104 / 7739
3
(HPO:0010804) Tented upper lip vermilion Frequent [Orphanet] 47 / 7739
4
(HPO:0010761) Broad columella Very frequent [Orphanet] 10 / 7739
5
(HPO:0001999) Abnormal facial shape Very frequent [Orphanet] 169 / 7739
6
(HPO:0100540) Palpebral edema Very frequent [Orphanet] 31 / 7739
7
(HPO:0000574) Thick eyebrow Frequent [Orphanet] 96 / 7739
8
(HPO:0011262) Crimped helix Very frequent [Orphanet] 12 / 7739
9
(HPO:0000356) Abnormality of the outer ear Frequent [Orphanet] 85 / 7739
10
(HPO:0001315) Reduced tendon reflexes Very frequent [Orphanet] 160 / 7739
11
(HPO:0001182) Tapered finger Very frequent [Orphanet] 93 / 7739
12
(HPO:0002857) Genu valgum Very frequent [Orphanet] 144 / 7739
13
(HPO:0001833) Long foot Frequent [Orphanet] 33 / 7739
14
(HPO:0001176) Large hands Frequent [Orphanet] 43 / 7739
15
(HPO:0000098) Tall stature Frequent [Orphanet] 74 / 7739
16
(HPO:0001513) Obesity Very frequent [Orphanet] 172 / 7739
17
(HPO:0004325) Decreased body weight Frequent [Orphanet] 492 / 7739
18
(HPO:0007477) Abnormal dermatoglyphics Very frequent [Orphanet] 72 / 7739
19
(HPO:0001252) Muscular hypotonia Very frequent [Orphanet] 990 / 7739
20
(HPO:0012758) Neurodevelopmental delay Very frequent [Orphanet] 949 / 7739

Associated genes:

ClinVar (via SNiPA)

Gene symbol Variation Clinical significance Reference

Additional Information: