Symptom Information: Sort according to HPO 

1
 (HPO:0012753) T2 hypointense basal ganglia Very frequent [IBIS] 100% (n=24) 21981780 IBIS 1 / 7739
2
 (HPO:0001260) Dysarthria Very frequent [IBIS] 90% (n=21) 23269600 IBIS 329 / 7739
3
 (HPO:0000750) Delayed speech and language development Frequent [IBIS] 556% (n=18) 21981780 IBIS 197 / 7739
4
 (HPO:0002460) Distal muscle weakness Frequent [IBIS] 86% (n=21) 23269600 IBIS 122 / 7739
5
 (HPO:0001257) Spasticity Frequent [IBIS] 78% (n=18) 21981780 IBIS 251 / 7739
6
 (HPO:0001347) Hyperreflexia Frequent [IBIS] 78% (n=18) 21981780 IBIS 363 / 7739
7
 (HPO:0003487) Babinski sign Frequent [IBIS] 78% (n=18) 21981780 IBIS 179 / 7739
8
 (HPO:0000648) Optic atrophy Frequent [IBIS] 74% (n=23) 23269600 IBIS 238 / 7739
9
 (HPO:0001288) Gait disturbance Frequent [IBIS] 73% (n=23) 23269600 IBIS 318 / 7739
10
 (HPO:0001300) Parkinsonism Frequent [IBIS] 72% (n=18) 21981780 IBIS 75 / 7739
11
 (HPO:0012048) Oromandibular dystonia Frequent [IBIS] 72% (n=18) 21981780 IBIS 7 / 7739
12
 (HPO:0007325) Generalized dystonia Frequent [IBIS] 72% (n=18) 21981780 IBIS 7 / 7739
13
 (HPO:0001332) Dystonia Frequent [IBIS] 71% (n=21) 23269600 IBIS 197 / 7739
14
 (HPO:0002015) Dysphagia Frequent [IBIS] 52% (n=21) 23269600 IBIS 301 / 7739
15
 (HPO:0007002) Motor axonal neuropathy Frequent [IBIS] 44% (n=18) 21981780 IBIS 17 / 7739
16
 (HPO:0000529) Progressive visual loss 22508347 IBIS 54 / 7739
17
 (HPO:0000712) Emotional lability 21981780 IBIS 44 / 7739
18
 (HPO:0000726) Dementia 23269600 IBIS 131 / 7739
19
 (HPO:0001251) Ataxia 21981780 IBIS 413 / 7739
20
 (HPO:0002311) Incoordination 21981780 IBIS 84 / 7739
21
 (HPO:0001249) Intellectual disability 22584950 IBIS 1089 / 7739
22
 (HPO:0001263) Global developmental delay 22584950 IBIS 853 / 7739
23
 (HPO:0001265) Hyporeflexia 22584950 IBIS 208 / 7739
24
 (HPO:0001284) Areflexia 23269600 IBIS 198 / 7739
25
 (HPO:0001315) Reduced tendon reflexes 23269600 IBIS 160 / 7739
26
 (HPO:0001337) Tremor 21981780 IBIS 200 / 7739
27
 (HPO:0001761) Pes cavus 23521069 IBIS 225 / 7739
28
 (HPO:0002366) Abnormal lower motor neuron morphology 23269600 IBIS 12 / 7739
29
 (HPO:0003236) Elevated serum creatine phosphokinase 23521069 IBIS 214 / 7739
30
 (HPO:0003691) Scapular winging 22584950 IBIS 51 / 7739
31
 (HPO:0003693) Distal amyotrophy 22584950 IBIS 118 / 7739
32
 (HPO:0100315) Lewy bodies 21981780 IBIS 5 / 7739
33
 (HPO:0100710) Impulsivity 21981780 IBIS 16 / 7739
34
 (OMIM) Atrophy of the small muscles in the hand 22584950 IBIS 1 / 7739
35
 (MedDRA:10057689) Acquired claw toe 22584950 IBIS 4 / 7739
36
 (HPO:0002071) Abnormality of extrapyramidal motor function 23521069 IBIS 76 / 7739
37
 (HPO:0007256) Abnormal pyramidal signs 22584950 IBIS 116 / 7739
38
 (OMIM) Upper motor neuron signs, early 23269600 IBIS 1 / 7739
39
 (OMIM) Lower motor neuron signs, later 23269600 IBIS 1 / 7739
40
 (HPO:0001268) Mental deterioration 21981780 IBIS 88 / 7739
41
 (OMIM) Iron accumulation in the globus pallidus and substantia nigra seen on MRI 21981780 IBIS 1 / 7739
42
 (OMIM) Iron-containing deposits in various brain regions 21981780 IBIS 1 / 7739
43
 (OMIM) Axonal spheroids 21981780 IBIS 2 / 7739
44
 (OMIM) Tau-containing inclusions 21981780 IBIS 1 / 7739
45
 (OMIM) Alpha-synuclein-containing inclusions 21981780 IBIS 1 / 7739
46
 (OMIM) Loss of myelin in the pyramidal tracts 21981780 IBIS 1 / 7739
47
 (OMIM) Reduced nerve amplitudes of peroneal nerve 22584950 IBIS 1 / 7739
48
 (MedDRA:10010219) Compulsions 21981780 IBIS 3 / 7739
49
 (HPO:0000716) Depression 21981780 IBIS 99 / 7739
50
 (MedDRA:10070246) Executive dysfunction 22584950 IBIS 6 / 7739
51
 (OMIM) Increased serum creatine kinase, mild 23521069 IBIS 2 / 7739
52
 (HPO:0000722) Obsessive-compulsive behavior 21981780 IBIS 35 / 7739
53
 (HPO:0001285) Spastic tetraparesis 21981780 IBIS 29 / 7739
54
 (HPO:0012677) Iron accumulation in globus pallidus 21981780 IBIS 1 / 7739
55
 (HPO:0012678) Iron accumulation in substantia nigra 21981780 IBIS 1 / 7739
56
 (HPO:0100314) Cerebral inclusion bodies 21981780 IBIS 2 / 7739
57
 (HPO:0011400) Abnormal CNS myelination 21981780 IBIS 10 / 7739
58
 (HPO:0002067) Bradykinesia 23521069 IBIS 62 / 7739
59
 (HPO:0000338) Hypomimic face 23521069 IBIS 8 / 7739
60
 (HPO:0001272) Cerebellar atrophy 23521069 IBIS 197 / 7739
61
 (HPO:0000551) Abnormality of color vision 23269600 IBIS 20 / 7739
62
 (HPO:0000640) Gaze-evoked nystagmus 23269600 IBIS 27 / 7739
63
 (HPO:0000571) Hypometric saccades 23269600 IBIS 10 / 7739
64
 (HPO:0007772) Impaired smooth pursuit 23269600 IBIS 21 / 7739
65
 (HPO:0000020) Urinary incontinence 23269600 IBIS 75 / 7739
66
 (HPO:0002607) Bowel incontinence 23269600 IBIS 33 / 7739
67
 (HPO:0100543) Cognitive impairment 23269600 IBIS 230 / 7739
68
 (HPO:0009130) Hand muscle atrophy 22584950 IBIS 11 / 7739
69
 (HPO:0011727) Peroneal muscle weakness 22584950 IBIS 6 / 7739
70
 (HPO:0001780) Abnormality of toe 22584950 IBIS 5 / 7739
71
 (HPO:0002127) Abnormal upper motor neuron morphology 23269600 IBIS 15 / 7739