Symptom Information: Sort according to HPO 

1
 (HPO:0002839) Urinary bladder sphincter dysfunction Very frequent [IBIS] 94% 23443022 IBIS 34 / 7739
2
 (HPO:0002079) Hypoplasia of the corpus callosum Very frequent [IBIS] 22266886 IBIS 161 / 7739
3
 (HPO:0001258) Spastic paraplegia Very frequent [IBIS] 22266886 IBIS 97 / 7739
4
 (HPO:0001260) Dysarthria Frequent [IBIS] 80% 22266886 IBIS 329 / 7739
5
 (HPO:0100543) Cognitive impairment Frequent [IBIS] 80% 22266886 IBIS 230 / 7739
6
 (HPO:0002355) Difficulty walking Frequent [IBIS] 75% 19105190 IBIS 61 / 7739
7
 (HPO:0008969) Leg muscle stiffness Frequent [IBIS] 75% 19105190 IBIS 5 / 7739
8
 (HPO:0003393) Thenar muscle atrophy Frequent [IBIS] 50% 22266886 IBIS 10 / 7739
9
 (HPO:0000020) Urinary incontinence Frequent [IBIS] 44% 23443022 IBIS 75 / 7739
10
 (HPO:0001288) Gait disturbance Frequent [IBIS] Very frequent [Orphanet] 19105190 IBIS 318 / 7739
11
 (HPO:0002120) Cerebral cortical atrophy Frequent [IBIS] Very frequent [Orphanet] 22266886 IBIS 187 / 7739
12
 (HPO:0000763) Sensory neuropathy Frequent [IBIS] 22266886 IBIS 78 / 7739
13
 (HPO:0007178) Motor polyneuropathy Frequent [IBIS] 22266886 IBIS 31 / 7739
14
 (HPO:0003390) Sensory axonal neuropathy Frequent [IBIS] 22266886 IBIS 26 / 7739
15
 (HPO:0003477) Peripheral axonal neuropathy Frequent [IBIS] 22266886 IBIS 62 / 7739
16
 (HPO:0007141) Sensorimotor neuropathy Frequent [IBIS] 22266886 IBIS 27 / 7739
17
 (HPO:0009830) Peripheral neuropathy Frequent [IBIS] 22266886 IBIS 206 / 7739
18
 (HPO:0001347) Hyperreflexia Occasional [Orphanet] 19105190 IBIS 363 / 7739
19
 (HPO:0000496) Abnormality of eye movement Very frequent [Orphanet] 26937357 IBIS 79 / 7739
20
 (HPO:0001276) Hypertonia Very frequent [Orphanet] 18337587 IBIS 317 / 7739
21
 (HPO:0001274) Agenesis of corpus callosum 27957547 IBIS 142 / 7739
22
 (HPO:0007370) Aplasia/Hypoplasia of the corpus callosum Very frequent [Orphanet] 26937357 IBIS 180 / 7739
23
 (HPO:0001250) Seizures Very frequent [Orphanet] 18337587 IBIS 1245 / 7739
24
 (HPO:0001251) Ataxia 19105190 IBIS 413 / 7739
25
 (HPO:0002066) Gait ataxia Very frequent [Orphanet] 18337587 IBIS 327 / 7739
26
 (HPO:0002119) Ventriculomegaly Very frequent [Orphanet] 19194956 IBIS 253 / 7739
27
 (HPO:0001249) Intellectual disability 19105190 IBIS 1089 / 7739
28
 (HPO:0001328) Specific learning disability 19105190 IBIS 114 / 7739
29
 (HPO:0000012) Urinary urgency 19105190 IBIS 35 / 7739
30
 (HPO:0000505) Visual impairment 19194956 IBIS 297 / 7739
31
 (HPO:0000546) Retinal degeneration 19194956 IBIS 61 / 7739
32
 (HPO:0000608) Macular degeneration 19194956 IBIS 36 / 7739
33
 (HPO:0000640) Gaze-evoked nystagmus 26937357 IBIS 27 / 7739
34
 (HPO:0001268) Mental deterioration 19105190 IBIS 88 / 7739
35
 (HPO:0001513) Obesity 23443022 IBIS 172 / 7739
36
 (HPO:0001761) Pes cavus 19105190 IBIS 225 / 7739
37
 (HPO:0002015) Dysphagia 23443022 IBIS 301 / 7739
38
 (HPO:0002061) Lower limb spasticity 19105190 IBIS 56 / 7739
39
 (HPO:0002064) Spastic gait 26937357 IBIS 46 / 7739
40
 (HPO:0002166) Impaired vibration sensation in the lower limbs 19194956 IBIS 26 / 7739
41
 (HPO:0002167) Neurological speech impairment Very frequent [Orphanet] 18337587 IBIS 308 / 7739
42
 (HPO:0002314) Degeneration of the lateral corticospinal tracts 17322883 IBIS 9 / 7739
43
 (HPO:0030051) Tip-toe gait 25758904 IBIS 10 / 7739
44
 (HPO:0002518) Abnormality of the periventricular white matter 19194956 IBIS 24 / 7739
45
 (HPO:0003380) Decreased number of peripheral myelinated nerve fibers 27544499 IBIS 30 / 7739
46
 (HPO:0003487) Babinski sign 18337587 IBIS 179 / 7739
47
 (HPO:0007067) Distal peripheral sensory neuropathy 19194956 IBIS 1 / 7739
48
 (HPO:0007340) Lower limb muscle weakness 19105190 IBIS 61 / 7739
49
 (HPO:0011448) Ankle clonus 26937357 IBIS 31 / 7739
50
 (HPO:0011449) Knee clonus 18337587 IBIS 10 / 7739
51
 (HPO:0003202) Skeletal muscle atrophy 22266886 IBIS 281 / 7739
52
 (OMIM) Atrophy of the thenar and hypothenar muscles 22266886 IBIS 1 / 7739
53
 (HPO:0007256) Abnormal pyramidal signs 19105190 IBIS 116 / 7739
54
 (HPO:0012638) Abnormality of nervous system physiology Occasional [Orphanet] 27544499 IBIS 12 / 7739
55
 (HPO:0003676) Progressive disorder 18337587 IBIS 148 / 7739
56
 (HPO:0002500) Abnormality of the cerebral white matter Frquent [IBIS] 22266886 IBIS 73 / 7739
57
 (HPO:0007354) Amyotrophic lateral sclerosis 22266886 IBIS 25 / 7739
58
 (HPO:0001300) Parkinsonism 22266886 IBIS 75 / 7739
59
 (HPO:0009130) Hand muscle atrophy 22266886 IBIS 11 / 7739
60
 (HPO:0001263) Global developmental delay 19105190 IBIS 853 / 7739
61
 (HPO:0200085) Limb tremor 19105190 IBIS 6 / 7739
62
 (HPO:0006801) Hyperactive deep tendon reflexes 19105190 IBIS 21 / 7739
63
 (HPO:0001272) Cerebellar atrophy 19105190 IBIS 197 / 7739
64
 (HPO:0002073) Progressive cerebellar ataxia 19105190 IBIS 27 / 7739
65
 (HPO:0002071) Abnormality of extrapyramidal motor function 19105190 IBIS 76 / 7739
66
 (HPO:0007663) Reduced visual acuity 19105190 IBIS 100 / 7739
67
 (HPO:0007302) Bipolar affective disorder 19105190 IBIS 15 / 7739
68
 (HPO:0000709) Psychosis 19105190 IBIS 61 / 7739
69
 (HPO:0000738) Hallucinations 19105190 IBIS 60 / 7739
70
 (HPO:0001760) Abnormality of the foot 19105190 IBIS 96 / 7739
71
 (HPO:0010845) EEG with generalized slow activity 19105190 IBIS 2 / 7739
72
 (HPO:0002527) Falls 19105190 IBIS 10 / 7739
73
 (HPO:0003693) Distal amyotrophy 26937357 IBIS 118 / 7739
74
 (HPO:0000726) Dementia 26937357 IBIS 131 / 7739
75
 (HPO:0000488) Retinopathy 26937357 IBIS 75 / 7739
76
 (HPO:0003563) Hypobetalipoproteinemia 25769290 IBIS 9 / 7739
77
 (HPO:0002075) Dysdiadochokinesis 18337587 IBIS 40 / 7739
78
 (HPO:0002371) Loss of speech 23443022 IBIS 15 / 7739
79
 (HPO:0002510) Spastic tetraplegia 23443022 IBIS 54 / 7739
80
 (HPO:0001371) Flexion contracture 23443022 IBIS 220 / 7739
81
 (HPO:0002607) Bowel incontinence 23443022 IBIS 33 / 7739
82
 (HPO:0000508) Ptosis 18337587 IBIS 459 / 7739
83
 (HPO:0000571) Hypometric saccades 18337587 IBIS 10 / 7739