Spastic tetraplegia

Symptom Information:

Symptom ID: HPO:0002510
Synonyms:
Spastic quadriplegia [HPO:0002510]
Spastic quadriplegia [OMIM:Spastic quadriplegia]
Spastic tetraplegia [OMIM:Spastic tetraplegia]
Spastic quadriplegia (in one patient) [OMIM:Spastic quadriplegia (in one patient)]
Spastic tetraplegia (in some patients) [OMIM:Spastic tetraplegia (in some patients)]
Spastic tetraplegia (onset in the second decade) [OMIM:Spastic tetraplegia (onset in the second decade)]
Quality:
Cross references:
OMIM: "Spastic quadriplegia" [OMIM:Spastic quadriplegia]
OMIM: "Spastic tetraplegia" [OMIM:Spastic tetraplegia]
OMIM: "Spastic quadriplegia (in one patient)" [OMIM:Spastic quadriplegia (in one patient)]
OMIM: "Spastic tetraplegia (in some patients)" [OMIM:Spastic tetraplegia (in some patients)]
OMIM: "Spastic tetraplegia (onset in the second decade)" [OMIM:Spastic tetraplegia (onset in the second decade)]
Is a (Direct Parents):
HPO         Spasticity
Is a (Whole tree): HPO:
All(HPO:0000001)
    Phenotypic abnormality(HPO:0000118)
       Abnormality of the nervous system(HPO:0000707)
          Abnormality of nervous system physiology(HPO:0012638)
             Abnormality of central motor function(HPO:0011442)
                Abnormal pyramidal signs(HPO:0007256)
                   Hypertonia(HPO:0001276)
                      Spasticity(HPO:0001257)
                         Spastic tetraplegia(HPO:0002510)
MedDRA:
Database Frequency: 54 / 7739
Resource:

All diseases associated with this symptom:

3-methylglutaconic aciduria type 1 (Orphanet:67046)
3-phosphoglycerate dehydrogenase deficiency (Orphanet:79351)
ASPARAGINE SYNTHETASE DEFICIENCY (OMIM:615574)
Aldosterone-producing adenoma with seizures and neurological abnormalities (Orphanet:369929)
Allan-Herndon-Dudley syndrome (Orphanet:59)
Anophthalmia/microphthalmia - esophageal atresia (Orphanet:77298)
Autosomal recessive spastic paraplegia type 11 (Orphanet:2822)
Beta-mannosidosis (Orphanet:118)
CEREBRAL PALSY, SPASTIC QUADRIPLEGIC, 1 (OMIM:603513)
CEREBRAL PALSY, SPASTIC QUADRIPLEGIC, 2 (OMIM:612900)
CORTICAL DYSPLASIA, COMPLEX, WITH OTHER BRAIN MALFORMATIONS 2 (OMIM:615282)
CORTICAL DYSPLASIA, COMPLEX, WITH OTHER BRAIN MALFORMATIONS 3 (OMIM:615411)
CORTICAL DYSPLASIA, COMPLEX, WITH OTHER BRAIN MALFORMATIONS 4 (OMIM:615412)
Congenital ichthyosis - intellectual deficit - spastic quadriplegia (Orphanet:352333)
D-glyceric aciduria (Orphanet:941)
EPILEPTIC ENCEPHALOPATHY, EARLY INFANTILE, 11 (OMIM:613721)
EPILEPTIC ENCEPHALOPATHY, EARLY INFANTILE, 4 (OMIM:612164)
EPILEPTIC ENCEPHALOPATHY, EARLY INFANTILE, 5 (OMIM:613477)
Familial acute necrotizing encephalopathy (Orphanet:88619)
Fucosidosis (Orphanet:349)
GM1 gangliosidosis type 2 (Orphanet:79256)
Galloway-Mowat syndrome (Orphanet:2065)
Hypotonia with lactic acidemia and hyperammonemia (Orphanet:137908)
Hypotonia-speech impairment-severe cognitive delay syndrome (Orphanet:371364)
Infantile neuroaxonal dystrophy (Orphanet:35069)
Infantile-onset ascending hereditary spastic paralysis (Orphanet:293168)
Inherited congenital spastic tetraplegia (Orphanet:210141)
Leigh syndrome with leukodystrophy (Orphanet:255241)
Lissencephaly due to TUBA1A mutation (Orphanet:171680)
MENTAL RETARDATION, AUTOSOMAL DOMINANT 13 (OMIM:614563)
METACHROMATIC LEUKODYSTROPHY (OMIM:250100)
MICROCEPHALY WITH SPASTIC QUADRIPLEGIA (OMIM:251280)
MICROHYDRANENCEPHALY (OMIM:605013)
Micrencephaly - corpus callosum agenesis - abnormal genitalia (Orphanet:2508)
Mucolipidosis type 4 (Orphanet:578)
NEURODEGENERATION WITH BRAIN IRON ACCUMULATION 2A (OMIM:256600)
NEURODEGENERATION WITH BRAIN IRON ACCUMULATION 6 (OMIM:615643)
Neurologic Waardenburg-Shah syndrome (Orphanet:163746)
OPTICOCOCHLEODENTATE DEGENERATION (OMIM:258700)
PONTOCEREBELLAR HYPOPLASIA, TYPE 2D (OMIM:613811)
PONTOCEREBELLAR HYPOPLASIA, TYPE 2E (OMIM:615851)
Pyruvate dehydrogenase E1-alpha deficiency (Orphanet:79243)
Pyruvate dehydrogenase E3 deficiency (Orphanet:2394)
Pyruvate dehydrogenase E3-binding protein deficiency (Orphanet:255182)
Pyruvate dehydrogenase lipoic acid synthetase deficiency (OMIM:614462)
SPASTIC PARAPLEGIA 50, AUTOSOMAL RECESSIVE (OMIM:612936)
SPASTIC PARAPLEGIA 51, AUTOSOMAL RECESSIVE (OMIM:613744)
Severe intellectual deficit and progressive spastic paraplegia (Orphanet:280763)
Spastic tetraplegia - retinitis pigmentosa - intellectual deficit (Orphanet:3011)
Sulfite oxidase deficiency due to molybdenum cofactor deficiency type A (Orphanet:308386)
Sulfite oxidase deficiency due to molybdenum cofactor deficiency type B (Orphanet:308393)
WARBURG MICRO SYNDROME 3 (OMIM:614222)
WARBURG MICRO SYNDROME 4 (OMIM:615663)
X-linked intellectual disability-cardiomegaly-congestive heart failure syndrome (Orphanet:324410)