Lower limb muscle weakness

Symptom Information:

Symptom ID: HPO:0007340
Synonyms:
LEG WEAKNESS [HPO:0007340]
Lower extremity weakness [HPO:0007340]
Lower limb weakness [HPO:0007340]
Muscle weakness in lower limbs [HPO:0007340]
Leg weakness [OMIM:Leg weakness]
Lower extremity weakness [OMIM:Lower extremity weakness]
Lower limb muscle weakness [OMIM:Lower limb muscle weakness]
Lower limb weakness [OMIM:Lower limb weakness]
Muscle weakness in lower limbs [OMIM:Muscle weakness in lower limbs]
Lower limb muscle weakness (in 2 of 3 families) [OMIM:Lower limb muscle weakness (in 2 of 3 families)]
Lower limb muscle weakness (occurs later) [OMIM:Lower limb muscle weakness (occurs later)]
Muscle weakness, lower limbs [OMIM:Muscle weakness, lower limbs]
Muscular weakness of both legs [IBIS,cm]
Hyposthenia of the lower limbs [IBIS,cm]
Quality:
Cross references:
OMIM: "Leg weakness" [OMIM:Leg weakness]
OMIM: "Lower extremity weakness" [OMIM:Lower extremity weakness]
OMIM: "Lower limb muscle weakness" [OMIM:Lower limb muscle weakness]
OMIM: "Lower limb weakness" [OMIM:Lower limb weakness]
OMIM: "Muscle weakness in lower limbs" [OMIM:Muscle weakness in lower limbs]
OMIM: "Lower limb muscle weakness (in 2 of 3 families)" [OMIM:Lower limb muscle weakness (in 2 of 3 families)]
OMIM: "Lower limb muscle weakness (occurs later)" [OMIM:Lower limb muscle weakness (occurs later)]
OMIM: "Muscle weakness, lower limbs" [OMIM:Muscle weakness, lower limbs]
Is a (Direct Parents):
HPO         Limb muscle weakness
Is a (Whole tree): HPO:
All(HPO:0000001)
    Phenotypic abnormality(HPO:0000118)
       Abnormality of the musculature(HPO:0003011)
          Abnormality of muscle physiology(HPO:0011804)
             Muscle weakness(HPO:0001324)
                Limb muscle weakness(HPO:0003690)
                   Lower limb muscle weakness(HPO:0007340)
MedDRA:
Database Frequency: 61 / 7739
Resource:

All diseases associated with this symptom:

Acute interstitial pneumonia (Orphanet:79126)
Autosomal dominant spastic paraplegia type 10 (Orphanet:100991)
Autosomal dominant spastic paraplegia type 12 (Orphanet:100993)
Autosomal dominant spastic paraplegia type 13 (Orphanet:100994)
Autosomal dominant spastic paraplegia type 17 (Orphanet:100998)
Autosomal dominant spastic paraplegia type 19 (Orphanet:100999)
Autosomal dominant spastic paraplegia type 3 (Orphanet:100984)
Autosomal dominant spastic paraplegia type 31 (Orphanet:101011)
Autosomal dominant spastic paraplegia type 36 (Orphanet:320365)
Autosomal dominant spastic paraplegia type 38 (Orphanet:171617)
Autosomal dominant spastic paraplegia type 4 (Orphanet:100985)
Autosomal dominant spastic paraplegia type 41 (Orphanet:320355)
Autosomal dominant spastic paraplegia type 42 (Orphanet:171863)
Autosomal dominant spastic paraplegia type 6 (Orphanet:100988)
Autosomal dominant spastic paraplegia type 8 (Orphanet:100989)
Autosomal dominant spastic paraplegia type 9 (Orphanet:100990)
Autosomal recessive Emery-Dreifuss muscular dystrophy (Orphanet:98855)
Autosomal recessive limb-girdle muscular dystrophy type 2B (Orphanet:268)
Autosomal recessive spastic paraplegia type 11 (Orphanet:2822)
Autosomal recessive spastic paraplegia type 14 (Orphanet:100995)
Autosomal recessive spastic paraplegia type 15 (Orphanet:100996)
Autosomal recessive spastic paraplegia type 18 (Orphanet:209951)
Autosomal recessive spastic paraplegia type 20 (Orphanet:101000)
Autosomal recessive spastic paraplegia type 21 (Orphanet:101001)
Autosomal recessive spastic paraplegia type 23 (Orphanet:101003)
Autosomal recessive spastic paraplegia type 28 (Orphanet:101008)
Autosomal recessive spastic paraplegia type 30 (Orphanet:101010)
Autosomal recessive spastic paraplegia type 32 (Orphanet:171622)
Autosomal recessive spastic paraplegia type 46 (Orphanet:320391)
Autosomal recessive spastic paraplegia type 48 (Orphanet:306511)
Autosomal recessive spastic paraplegia type 54 (Orphanet:320380)
Autosomal recessive spastic paraplegia type 55 (Orphanet:320375)
Autosomal recessive spastic paraplegia type 5A (Orphanet:100986)
Autosomal recessive spastic paraplegia type 7 (Orphanet:99013)
Beta-mannosidosis (Orphanet:118)
CEREBRAL SCLEROSIS, DIFFUSE, SCHOLZ TYPE (OMIM:302700)
Friedreich ataxia 1 (OMIM:229300)
Gerstmann-Straussler-Scheinker syndrome (Orphanet:356)
Hurler-Scheie syndrome (Orphanet:93476)
Hyperornithinemia-hyperammonemia-homocitrullinuria (Orphanet:415)
Hypomyelination - congenital cataract (Orphanet:85163)
MIYOSHI MUSCULAR DYSTROPHY 1 (OMIM:254130)
McLeod neuroacanthocytosis syndrome (Orphanet:59306)
Mitochondrial DNA deletion syndrome with progressive myopathy (Orphanet:352470)
Miyoshi myopathy (Orphanet:45448)
NEUROFIBROMATOSIS, FAMILIAL SPINAL (OMIM:162210)
NEURONOPATHY, DISTAL HEREDITARY MOTOR, TYPE IID (OMIM:615575)
NEURONOPATHY, DISTAL HEREDITARY MOTOR, TYPE VIIB (OMIM:607641)
NEUROPATHY, PAINFUL (OMIM:256870)
PARTIAL LIPODYSTROPHY, CONGENITAL CATARACTS, AND NEURODEGENERATIONSYNDROME (OMIM:606721)
Primary hyperoxaluria type 1 (Orphanet:93598)
Pyruvate dehydrogenase E1-alpha deficiency (Orphanet:79243)
SCAPULOPERONEAL MYOPATHY, X-LINKED DOMINANT (OMIM:300695)
SPASTIC PARAPLEGIA, ATAXIA, AND MENTAL RETARDATION (OMIM:607565)
Scheie syndrome (Orphanet:93474)
Spastic paraplegia - epilepsy - intellectual deficit (Orphanet:2816)
Spastic paraplegia 33, autosomal dominant (OMIM:610244)
Spastic paraplegia type 2 (Orphanet:99015)
Symptomatic form of muscular dystrophy of Duchenne and Becker in female carriers (Orphanet:206546)
X-linked spastic paraplegia type 16 (Orphanet:100997)
[DEL] SPASTIC PARAPLEGIA 7, AUTOSOMAL RECESSIVE (OMIM:607259)