Single transverse palmar crease

Symptom Information:

Symptom ID: HPO:0000954
Synonyms:
Simian crease [HPO:0000954]
Simian creases [HPO:0000954]
Single flexion crease [HPO:0000954]
Single palmar crease [HPO:0000954]
Single palmar creases [HPO:0000954]
Single transverse palmar creases [HPO:0000954]
Transverse palmar crease [HPO:0000954]
Single transverse palmar crease (finding) [Orphanet:20200]
Single transverse palmar crease [Orphanet:20200]
Simian crease [OMIM:Simian crease]
Simian creases [OMIM:Simian creases]
Single flexion crease [OMIM:Single flexion crease]
Single palmar crease [OMIM:Single palmar crease]
Single palmar creases [OMIM:Single palmar creases]
Single transverse palmar crease [OMIM:Single transverse palmar crease]
Single transverse palmar creases [OMIM:Single transverse palmar creases]
Transverse palmar crease [OMIM:Transverse palmar crease]
Simian crease/transverse/unique palmar crease [Orphanet:20200]
Simian crease [Orphanet:20200]
Abnormal palmar/plantar creases [MedDRA:10000162]
Abnormal single palmar crease [MedDRA:10000162]
Simian crease [MedDRA:10000162]
Simian crease (in some patients) [OMIM:Simian crease (in some patients)]
Single transverse palmar crease (in some patients) [OMIM:Single transverse palmar crease (in some patients)]
Transverse palmar crease (in some patients) [OMIM:Transverse palmar crease (in some patients)]
Transverse palmar creases [OMIM:Transverse palmar creases]
Quality:
Cross references:
HPO:0007598 "Bilateral single transverse palmar creases" [Orphanet:20200]
Orphanet:20200 "Simian crease/transverse/unique palmar crease" [Orphanet:20200]
OMIM: "Simian crease" [OMIM:Simian crease]
OMIM: "Simian creases" [OMIM:Simian creases]
OMIM: "Single flexion crease" [OMIM:Single flexion crease]
OMIM: "Single palmar crease" [OMIM:Single palmar crease]
OMIM: "Single palmar creases" [OMIM:Single palmar creases]
OMIM: "Single transverse palmar crease" [OMIM:Single transverse palmar crease]
OMIM: "Single transverse palmar creases" [OMIM:Single transverse palmar creases]
OMIM: "Transverse palmar crease" [OMIM:Transverse palmar crease]
OMIM: "Simian crease (in some patients)" [OMIM:Simian crease (in some patients)]
OMIM: "Single transverse palmar crease (in some patients)" [OMIM:Single transverse palmar crease (in some patients)]
OMIM: "Transverse palmar crease (in some patients)" [OMIM:Transverse palmar crease (in some patients)]
OMIM: "Transverse palmar creases" [OMIM:Transverse palmar creases]
UMLS:C0424731 "Single transverse palmar crease" [Orphanet:20200]
Is a (Direct Parents):
HPO         Abnormality of the palmar creases
MedDRA Skin and subcutaneous conditions NEC
Orphanet Abnormality of the hand
Is a (Whole tree): HPO:
All(HPO:0000001)
    Phenotypic abnormality(HPO:0000118)
       Abnormality of the integument(HPO:0001574)
          Abnormality of the skin(HPO:0000951)
             Regional abnormality of skin(HPO:0011356)
                Abnormal dermatoglyphics(HPO:0007477)
                   Abnormal palmar dermatoglyphics(HPO:0001018)
                      Abnormality of the palmar creases(HPO:0010490)
                         Single transverse palmar crease(HPO:0000954)
       Abnormality of the skeletal system(HPO:0000924)
          Abnormality of skeletal morphology(HPO:0011842)
             Abnormal appendicular skeleton morphology(HPO:0011844)
                Abnormality of limb bone morphology(HPO:0002813)
                   Abnormality of the upper limb(HPO:0002817)
                      Abnormality of the hand(HPO:0001155)
                         Abnormality of the palm(HPO:0100871)
                            Abnormal palmar dermatoglyphics(HPO:0001018)
                               Abnormality of the palmar creases(HPO:0010490)
                                  Single transverse palmar crease(HPO:0000954)
MedDRA:
Skin and subcutaneous tissue disorders(MedDRA:10040785)
    Skin and subcutaneous tissue disorders NEC(MedDRA:10040790)
       Skin and subcutaneous conditions NEC(MedDRA:10042356)
          Single transverse palmar crease(HPO:0000954)
Database Frequency: 162 / 7739
Resource:

All diseases associated with this symptom:

14q22q23 microdeletion syndrome (Orphanet:264200)
15q24 microdeletion syndrome (Orphanet:94065)
16p11.2p12.2 microdeletion syndrome (Orphanet:261211)
17q23.1q23.2 microdeletion syndrome (Orphanet:261279)
2p15p16.1 microdeletion syndrome (Orphanet:261349)
2q37 microdeletion syndrome (Orphanet:1001)
3-methylglutaconic aciduria type 4 (Orphanet:67048)
AARSKOG SYNDROME, AUTOSOMAL DOMINANT (OMIM:100050)
AARSKOG-SCOTT SYNDROME (OMIM:305400)
ADAMS-OLIVER SYNDROME 2 (OMIM:614219)
ARTHROGRYPOSIS, DISTAL, TYPE 1A (OMIM:108120)
ATP-BINDING CASSETTE, SUBFAMILY D, MEMBER 3 (OMIM:170995)
Aarskog-Scott syndrome (Orphanet:915)
Absence of fingerprints - congenital milia (Orphanet:1658)
Acro-oto-ocular syndrome (Orphanet:2980)
Acrofacial dysostosis, Catania type (Orphanet:1786)
Acrofacial dysostosis, Rodriguez type (Orphanet:1788)
Acromesomelic dysplasia, Hunter-Thomson type (Orphanet:968)
Allan-Herndon-Dudley syndrome (Orphanet:59)
Anonychia - microcephaly (Orphanet:1094)
Antenatal multiminicore disease with arthrogryposis multiplex congenita (Orphanet:178148)
Aplasia cutis congenita - intestinal lymphangiectasia (Orphanet:1116)
Ataxia - photosensitivity - short stature (Orphanet:1184)
Autosomal recessive Robinow syndrome (Orphanet:1507)
Autosomal recessive severe congenital neutropenia due to G6PC3 deficiency (Orphanet:331176)
BILIARY MALFORMATION WITH RENAL TUBULAR INSUFFICIENCY (OMIM:210550)
BRACHYMESOMELIA-RENAL SYNDROME (OMIM:113470)
Blepharophimosis-intellectual deficit syndrome, SBBYS type (Orphanet:3047)
Branchio-oculo-facial syndrome (Orphanet:1297)
Böök syndrome (Orphanet:1262)
C syndrome (Orphanet:1308)
CATEL-MANZKE SYNDROME (OMIM:616145)
CHROMOSOME 6q11-q14 DELETION SYNDROMECHROMOSOME 6q13-q14 DELETION SYNDROME, INCLUDED (OMIM:613544)
CHST3-related skeletal dysplasia (Orphanet:263463)
COFFIN-SIRIS SYNDROME (OMIM:135900)
CORNELIA DE LANGE SYNDROME 1 (OMIM:122470)
Camptodactyly syndrome, Guadalajara type 2 (Orphanet:1326)
Cataract - deafness - hypogonadism (Orphanet:1383)
Catel-Manzke syndrome (Orphanet:1388)
Cleidorhizomelic syndrome (Orphanet:1453)
Coffin-Lowry syndrome (Orphanet:192)
Coffin-Siris syndrome (Orphanet:1465)
Cohen syndrome (Orphanet:193)
Conductive deafness - ptosis - skeletal anomalies (Orphanet:3236)
Congenital bile acid synthesis defect type 4 (Orphanet:79095)
Cornelia de Lange syndrome (Orphanet:199)
Cranioectodermal dysplasia (Orphanet:1515)
Cranioectodermal dysplasia 1 (OMIM:218330)
Craniosynostosis - fibular aplasia (Orphanet:1533)
Cryptorchidism - arachnodactyly - intellectual deficit (Orphanet:1548)
DESBUQUOIS DYSPLASIA 2 (OMIM:615777)
DPAGT1-CDG (Orphanet:86309)
Digitotalar dysmorphism (Orphanet:1146)
Distal monosomy 10p (Orphanet:1580)
Distal monosomy 17q (Orphanet:1597)
Distal monosomy 7q36 (Orphanet:1636)
Distal trisomy 18q (Orphanet:1716)
Down syndrome (Orphanet:870)
EHLERS-DANLOS SYNDROME, PROGEROID TYPE, 1 (OMIM:130070)
Ehlers-Danlos syndrome, progeroid type (Orphanet:75496)
Extrasystoles - short stature - hyperpigmentation - microcephaly (Orphanet:1964)
Fetal trimethadione syndrome (Orphanet:1913)
Fibular aplasia - complex brachydactyly (Orphanet:2639)
Filippi syndrome (Orphanet:3255)
Frontonasal dysplasia (Orphanet:250)
Fryns syndrome (Orphanet:2059)
Fuhrmann syndrome (Orphanet:2854)
Gonadal dysgenesis, XY type - associated anomalies (Orphanet:1770)
Gordon syndrome (Orphanet:376)
Intellectual deficit - athetosis - microphthalmia (Orphanet:1236)
Intellectual deficit - hypotonia - skin hyperpigmentation (Orphanet:3050)
Intellectual deficit - spasticity - ectrodactyly (Orphanet:1891)
Intellectual deficit, X-linked - cubitus valgus - dysmorphism (Orphanet:85280)
Intellectual deficit, X-linked - seizures - psoriasis (Orphanet:3052)
Intellectual deficit, X-linked, Wittwer type (Orphanet:85291)
Isolated plagiocephaly (Orphanet:35098)
Johanson-Blizzard syndrome (Orphanet:2315)
KBG syndrome (Orphanet:2332)
Kapur-Toriello syndrome (Orphanet:2328)
Kleefstra syndrome (Orphanet:261494)
Langer-Giedion syndrome (Orphanet:502)
Laurence-Moon syndrome (Orphanet:2377)
Lethal Larsen-like syndrome (Orphanet:2371)
Lethal faciocardiomelic dysplasia (Orphanet:1972)
Lichstenstein syndrome (Orphanet:2390)
Low birth weight - dwarfism - dysgammaglobulinemia (Orphanet:2621)
Lung agenesis - heart defect - thumb anomalies (Orphanet:1120)
MACS syndrome (Orphanet:217335)
MENTAL RETARDATION, X-LINKED, SYNDROMIC, CHUDLEY-SCHWARTZ TYPE (OMIM:300861)
MULTIPLE SYNOSTOSES SYNDROME 1 (OMIM:186500)
Marden-Walker syndrome (Orphanet:2461)
Maternal hyperthermia induced birth defects (Orphanet:2216)
McDonough syndrome (Orphanet:2471)
Melhem-Fahl syndrome (Orphanet:2482)
Mesoaxial synostotic syndactyly with phalangeal reduction (Orphanet:157801)
Mesomelic dwarfism, Nievergelt type (Orphanet:2633)
Microbrachycephaly - ptosis - cleft lip (Orphanet:2511)
Microcephalic osteodysplastic primordial dwarfism types 1 and 3 (Orphanet:2636)
Microcephaly - cardiac defect - lung malsegmentation (Orphanet:2516)
Microcephaly - intellectual deficit - phalangeal and neurological anomalies (Orphanet:137658)
Microlissencephaly - micromelia (Orphanet:50810)
Microphthalmia with brain and digit anomalies (Orphanet:139471)
Microphthalmia with limb anomalies (Orphanet:1106)
Miller-Dieker syndrome (Orphanet:531)
Monosomy 5p (Orphanet:281)
Monosomy 9p (Orphanet:261112)
Mosaic trisomy 14 (Orphanet:1703)
Multiple synostoses syndrome (Orphanet:3237)
Neonatal adrenoleukodystrophy (Orphanet:44)
Non-distal monosomy 10q (Orphanet:1581)
OPITZ-KAVEGGIA SYNDROME (OMIM:305450)
Oculocerebrofacial syndrome, Kaufman type (Orphanet:2707)
Odonto-tricho-ungual-digito-palmar syndrome (Orphanet:69082)
PEROXISOME BIOGENESIS DISORDER 1A (ZELLWEGER) (OMIM:214100)
PEROXISOME BIOGENESIS DISORDER 2A (ZELLWEGER) (OMIM:214110)
PEROXISOME BIOGENESIS DISORDER 3B (OMIM:266510)
PEROXISOME BIOGENESIS DISORDER 5A (ZELLWEGER) (OMIM:614866)
Penoscrotal transposition (Orphanet:2842)
Perlman syndrome (Orphanet:2849)
Peters-plus syndrome (Orphanet:709)
Pitt-Hopkins syndrome (Orphanet:2896)
Postaxial tetramelic oligodactyly (Orphanet:2730)
Potocki-Shaffer syndrome (Orphanet:52022)
Prader-Willi syndrome (Orphanet:739)
Prolidase deficiency (Orphanet:742)
Prominent glabella - microcephaly - hypogenitalism (Orphanet:2083)
Rasmussen-Johnsen-Thomsen syndrome (Orphanet:3023)
Recombinant 8 syndrome (Orphanet:96167)
Renal tubular dysgenesis (Orphanet:3033)
Roberts syndrome (Orphanet:3103)
Roifman syndrome (Orphanet:353298)
Rubinstein-Taybi syndrome due to CREBBP mutations (Orphanet:353277)
Rudiger syndrome (Orphanet:3118)
SECKEL SYNDROME 1 (OMIM:210600)
SHORT STATURE, OPTIC NERVE ATROPHY, AND PELGER-HUET ANOMALY (OMIM:614800)
SKELETAL DYSPLASIA AND PROGRESSIVE CENTRAL NERVOUS SYSTEM DEGENERATION,LETHAL (OMIM:602613)
Saethre-Chotzen syndrome (Orphanet:794)
Schilbach-Rott syndrome (Orphanet:2353)
Schinzel-Giedion syndrome (Orphanet:798)
Seckel syndrome (Orphanet:808)
Sheldon-Hall syndrome (Orphanet:1147)
Short rib-polydactyly syndrome (Orphanet:1505)
Short rib-polydactyly syndrome, Beemer-Langer type (Orphanet:93268)
Short stature - heart defect - craniofacial anomalies (Orphanet:1088)
Sillence syndrome (Orphanet:3168)
Simpson-Golabi-Behmel syndrome type 2 (Orphanet:79022)
Stüve-Wiedemann syndrome (Orphanet:3206)
Subaortic stenosis - short stature (Orphanet:3191)
TARP syndrome (Orphanet:2886)
Teebi-Shaltout syndrome (Orphanet:3291)
Tetrasomy 12p (Orphanet:884)
Trisomy 13 (Orphanet:3378)
Trisomy 18 (Orphanet:3380)
Trisomy 9p (Orphanet:236)
WT limb-blood syndrome (Orphanet:3466)
Warsaw breakage syndrome (Orphanet:280558)
Wolf-Hirschhorn syndrome (Orphanet:280)
X-linked distal arthrogryposis multiplex congenita (Orphanet:1145)
Yunis-Varon syndrome (Orphanet:3472)
Zellweger syndrome (Orphanet:912)
Zellweger-like syndrome without peroxisomal anomalies (Orphanet:50812)
Zlotogora-Ogur syndrome (Orphanet:3253)