Knee flexion contracture

Symptom Information:

Symptom ID: HPO:0006380
Synonyms:
Contractures of knees [HPO:0006380]
Contractures of the knees [HPO:0006380]
Flexion contracture of knees [HPO:0006380]
FLEXION CONTRACTURES AT BOTH KNEES [HPO:0006380]
Flexion contractures of knees [HPO:0006380]
Knee contracture [HPO:0006380]
Knee contractures [HPO:0006380]
Knee flexion contractures [HPO:0006380]
Knee flexion deformity [HPO:0006380]
Contractures of knees [OMIM:Contractures of knees]
Contractures of the knees [OMIM:Contractures of the knees]
Flexion contracture of knees [OMIM:Flexion contracture of knees]
Flexion contractures at both knees [OMIM:Flexion contractures at both knees]
Knee contracture [OMIM:Knee contracture]
Knee contractures [OMIM:Knee contractures]
Knee flexion contracture [OMIM:Knee flexion contracture]
Knee flexion contractures [OMIM:Knee flexion contractures]
Knee contractures (81%) [OMIM:Knee contractures (81%)]
Knee contractures (in some patients) [OMIM:Knee contractures (in some patients)]
Knee flexion deformities [OMIM:Knee flexion deformities]
Quality:
Cross references:
OMIM: "Contractures of knees" [OMIM:Contractures of knees]
OMIM: "Contractures of the knees" [OMIM:Contractures of the knees]
OMIM: "Flexion contracture of knees" [OMIM:Flexion contracture of knees]
OMIM: "Flexion contractures at both knees" [OMIM:Flexion contractures at both knees]
OMIM: "Knee contracture" [OMIM:Knee contracture]
OMIM: "Knee contractures" [OMIM:Knee contractures]
OMIM: "Knee flexion contracture" [OMIM:Knee flexion contracture]
OMIM: "Knee flexion contractures" [OMIM:Knee flexion contractures]
OMIM: "Knee contractures (81%)" [OMIM:Knee contractures (81%)]
OMIM: "Knee contractures (in some patients)" [OMIM:Knee contractures (in some patients)]
OMIM: "Knee flexion deformities" [OMIM:Knee flexion deformities]
Is a (Direct Parents):
HPO         Abnormality of the knee
HPO         Contractures of the joints of the lower limbs
Is a (Whole tree): HPO:
All(HPO:0000001)
    Phenotypic abnormality(HPO:0000118)
       Abnormality of connective tissue(HPO:0003549)
          Flexion contracture(HPO:0001371)
             Limb joint contracture(HPO:0003121)
                Contractures of the joints of the lower limbs(HPO:0005750)
                   Knee flexion contracture(HPO:0006380)
       Abnormality of the musculature(HPO:0003011)
          Abnormality of muscle morphology(HPO:0011805)
             Flexion contracture(HPO:0001371)
                Limb joint contracture(HPO:0003121)
                   Contractures of the joints of the lower limbs(HPO:0005750)
                      Knee flexion contracture(HPO:0006380)
       Abnormality of the skeletal system(HPO:0000924)
          Abnormality of skeletal morphology(HPO:0011842)
             Abnormal appendicular skeleton morphology(HPO:0011844)
                Abnormality of limb bone morphology(HPO:0002813)
                   Abnormality of the lower limb(HPO:0002814)
                      Abnormality of lower limb joint(HPO:0100491)
                         Abnormality of the knee(HPO:0002815)
                            Knee flexion contracture(HPO:0006380)
             Abnormal joint morphology(HPO:0001367)
                Abnormality of lower limb joint(HPO:0100491)
                   Abnormality of the knee(HPO:0002815)
                      Knee flexion contracture(HPO:0006380)
                Abnormality of joint mobility(HPO:0011729)
                   Flexion contracture(HPO:0001371)
                      Limb joint contracture(HPO:0003121)
                         Contractures of the joints of the lower limbs(HPO:0005750)
                            Knee flexion contracture(HPO:0006380)
MedDRA:
Database Frequency: 56 / 7739
Resource:

All diseases associated with this symptom:

ARTHROGRYPOSIS, CONGENITAL, LOWER LIMB, X-LINKED (OMIM:300158)
ARTHROGRYPOSIS, DISTAL, TYPE 1A (OMIM:108120)
ARTHROGRYPOSIS, DISTAL, TYPE 2A (OMIM:193700)
Argininemia (Orphanet:90)
Arthrogryposis - renal dysfunction - cholestasis (Orphanet:2697)
Autosomal dominant Emery-Dreifuss muscular dystrophy (Orphanet:98853)
Autosomal dominant childhood-onset proximal spinal muscular atrophy with contractures (Orphanet:363454)
Autosomal dominant chondrodysplasia punctata (Orphanet:79344)
Autosomal dominant congenital benign spinal muscular atrophy (Orphanet:1216)
Autosomal dominant limb-girdle muscular dystrophy type 1B (Orphanet:264)
Autosomal dominant multiple pterygium syndrome (Orphanet:65743)
Autosomal recessive distal osteolysis syndrome (Orphanet:2776)
Autosomal recessive spastic paraplegia type 43 (Orphanet:320370)
Autosomal recessive spastic paraplegia type 45 (Orphanet:320396)
BRACHYPHALANGY, POLYDACTYLY, AND TIBIAL APLASIA/HYPOPLASIA (OMIM:609945)
BRUCK SYNDROME 2 (OMIM:609220)
Bruck syndrome (Orphanet:2771)
CEREBROOCULOFACIOSKELETAL SYNDROME 1 (OMIM:214150)
CHROMOSOME 17p13.1 DELETION SYNDROME (OMIM:613776)
COFS syndrome (Orphanet:1466)
CONGENITAL CONTRACTURES OF THE LIMBS AND FACE, HYPOTONIA, AND DEVELOPMENTALDELAY (OMIM:616266)
Carnitine palmitoyl transferase II deficiency, neonatal form (Orphanet:228308)
Congenital contractural arachnodactyly (Orphanet:115)
DPM1-CDG (Orphanet:79322)
Digitotalar dysmorphism (Orphanet:1146)
Fetal Gaucher disease (Orphanet:85212)
Freeman-Sheldon syndrome (Orphanet:2053)
Frontometaphyseal dysplasia (Orphanet:1826)
Gaucher disease type 2 (Orphanet:77260)
Genitopatellar syndrome (Orphanet:85201)
Gordon syndrome (Orphanet:376)
Hurler-Scheie syndrome (Orphanet:93476)
Intellectual deficit - cataracts - calcified pinnae - myopathy (Orphanet:3042)
KAHRIZI SYNDROME (OMIM:612713)
KERATITIS-ICHTHYOSIS-DEAFNESS SYNDROME, AUTOSOMAL DOMINANT (OMIM:148210)
KID syndrome (Orphanet:477)
LETHAL CONGENITAL CONTRACTURE SYNDROME 7 (OMIM:616286)
Lenz-Majewski hyperostotic dwarfism (Orphanet:2658)
MENTAL RETARDATION, MICROCEPHALY, GROWTH RETARDATION, JOINT CONTRACTURES,AND FACIAL DYSMORPHISM (OMIM:606242)
MICROCEPHALIC OSTEODYSPLASTIC PRIMORDIAL DWARFISM, TYPE I (OMIM:210710)
MICROCEPHALIC OSTEODYSPLASTIC PRIMORDIAL DWARFISM, TYPE III (OMIM:210730)
Macrocephaly - spastic paraplegia - dysmorphism (Orphanet:2429)
Marden-Walker syndrome (Orphanet:2461)
Megalencephaly - polymicrogyria - postaxial polydactyly - hydrocephalus (Orphanet:83473)
Metaphyseal chondrodysplasia, Jansen type (Orphanet:33067)
Microcephalic osteodysplastic primordial dwarfism types 1 and 3 (Orphanet:2636)
Muscular dystrophy, Selcen type (Orphanet:199340)
OTOONYCHOPERONEAL SYNDROME (OMIM:259780)
ROBERTS SYNDROME (OMIM:268300)
Roberts syndrome (Orphanet:3103)
SC PHOCOMELIA SYNDROME (OMIM:269000)
Spondyloepimetaphyseal dysplasia - short limb - abnormal calcification (Orphanet:93358)
Spondylometaphyseal dysplasia, Golden type (Orphanet:168544)
Stüve-Wiedemann syndrome (Orphanet:3206)
Van den Ende-Gupta syndrome (Orphanet:2460)
WHISTLING FACE SYNDROME, RECESSIVE FORM (OMIM:277720)