Oral cleft

Symptom Information:

Symptom ID: HPO:0000202
Synonyms:
Cleft lip, cleft palate [HPO:0000202]
Cleft lip/palate [HPO:0000202]
Oral clefting [HPO:0000202]
Cleft lip and palate [Orphanet:9920]
Cleft palate with cleft lip (disorder) [Orphanet:9920]
Cheilopalatoschisis (disorder) [Orphanet:9920]
Cleft palate with cleft lip [Orphanet:9920]
Cleft lip, Cleft palate [OMIM:Cleft lip, Cleft palate]
Cleft lip/palate [OMIM:Cleft lip/palate]
Oral cleft [OMIM:Oral cleft]
Cleft lip and palate [MedDRA:10009260]
Cleft palate and cleft lip [MedDRA:10009260]
Cleft palate with cleft lip [MedDRA:10009260]
Cleft palate with cleft lip, bilateral, complete [MedDRA:10009260]
Cleft palate with cleft lip, bilateral, incomplete [MedDRA:10009260]
Cleft palate with cleft lip, unilateral, complete [MedDRA:10009260]
Cleft palate with cleft lip, unilateral, incomplete [MedDRA:10009260]
Cleft palate with cleft lip, unspecified [MedDRA:10009260]
Lip and palate cleft [MedDRA:10009260]
Other combinations of cleft palate with cleft lip [MedDRA:10009260]
Palate and lip cleft [MedDRA:10009260]
Cleft lip and cleft palate [OMIM:Cleft lip and cleft palate]
Cleft lip and palate [OMIM:Cleft lip and palate]
Cleft lip/palate (10%) [OMIM:Cleft lip/palate (10%)]
Cleft lip/palate (35%) [OMIM:Cleft lip/palate (35%)]
Cleft lip/palate (less common) [OMIM:Cleft lip/palate (less common)]
Cleft lip/palate. [OMIM:Cleft lip/palate.]
Orofacial clefting [IBIS, cm]
Quality:
Cross references:
Orphanet:9920 "Cleft lip and palate" [Orphanet:9920]
OMIM: "Cleft lip, Cleft palate" [OMIM:Cleft lip, Cleft palate]
OMIM: "Cleft lip/palate" [OMIM:Cleft lip/palate]
OMIM: "Oral cleft" [OMIM:Oral cleft]
OMIM: "Cleft lip and cleft palate" [OMIM:Cleft lip and cleft palate]
OMIM: "Cleft lip and palate" [OMIM:Cleft lip and palate]
OMIM: "Cleft lip/palate (10%)" [OMIM:Cleft lip/palate (10%)]
OMIM: "Cleft lip/palate (35%)" [OMIM:Cleft lip/palate (35%)]
OMIM: "Cleft lip/palate (less common)" [OMIM:Cleft lip/palate (less common)]
OMIM: "Cleft lip/palate." [OMIM:Cleft lip/palate.]
UMLS:C0158646 "Cleft palate with cleft lip" [Orphanet:9920]
Is a (Direct Parents):
HPO         Abnormality of the mouth
Orphanet Cleft upper lip
MedDRA Palate disorders congenital
Is a (Whole tree): HPO:
All(HPO:0000001)
    Phenotypic abnormality(HPO:0000118)
       Abnormality of head or neck(HPO:0000152)
          Abnormality of the head(HPO:0000234)
             Abnormality of the face(HPO:0000271)
                Abnormality of the mouth(HPO:0000153)
                   Oral cleft(HPO:0000202)
MedDRA:
Congenital, familial and genetic disorders(MedDRA:10010331)
    Gastrointestinal tract disorders congenital(MedDRA:10018018)
       Palate disorders congenital(MedDRA:10033530)
          Oral cleft(HPO:0000202)
Database Frequency: 120 / 7739
Resource:

All diseases associated with this symptom:

16p11.2p12.2 microdeletion syndrome (Orphanet:261211)
16p11.2p12.2 microduplication syndrome (Orphanet:261204)
1p36 deletion syndrome (Orphanet:1606)
22q11.2 deletion syndrome (Orphanet:567)
3C syndrome (Orphanet:7)
3q29 microdeletion syndrome (Orphanet:65286)
AARSKOG SYNDROME, AUTOSOMAL DOMINANT (OMIM:100050)
ADULT syndrome (Orphanet:978)
Aarskog-Scott syndrome (Orphanet:915)
Acro-renal-mandibular syndrome (Orphanet:958)
Acroosteolysis, dominant type (Orphanet:955)
Aicardi syndrome (Orphanet:50)
Ankyloblepharon filiforme adnatum - cleft palate (Orphanet:1072)
Arterial tortuosity syndrome (Orphanet:3342)
Auriculoocular anomalies - cleft lip (Orphanet:71270)
Autosomal dominant Robinow syndrome (Orphanet:3107)
Autosomal recessive Robinow syndrome (Orphanet:1507)
Autosomal recessive amelia (Orphanet:1027)
Autosomal recessive multiple pterygium syndrome (Orphanet:2990)
BARAITSER-WINTER SYNDROME 2 (OMIM:614583)
Bamforth syndrome (Orphanet:1226)
Baraitser-Winter syndrome (Orphanet:2995)
Bartsocas-Papas syndrome (Orphanet:1234)
Blepharo-cheilo-odontic syndrome (Orphanet:1997)
Borjeson-Forssman-Lehmann syndrome (Orphanet:127)
Bowen-Conradi syndrome (Orphanet:1270)
Branchio-oculo-facial syndrome (Orphanet:1297)
CARDIAC MALFORMATION, CLEFT LIP/PALATE, MICROCEPHALY AND DIGITAL ANOMALIES (OMIM:600987)
CHARGE syndrome (Orphanet:138)
CORNELIA DE LANGE SYNDROME 1 (OMIM:122470)
CRANIOSYNOSTOSIS-MENTAL RETARDATION-CLEFTING SYNDROME (OMIM:218650)
Cantrell pentalogy (Orphanet:1335)
Caudal regression sequence (Orphanet:3027)
Central congenital hypothyroidism (Orphanet:226298)
Cerebro-facio-thoracic dysplasia (Orphanet:1394)
Cleft lip/palate - deafness - sacral lipoma (Orphanet:2003)
Cleft lip/palate - intestinal malrotation - cardiopathy (Orphanet:2001)
Cleft palate (Orphanet:2014)
Cockayne syndrome (Orphanet:191)
Congenital hypothyroidism (Orphanet:442)
Contractures - ectodermal dysplasia - cleft lip/palate (Orphanet:1484)
Craniofrontonasal dysplasia (Orphanet:1520)
Cutis marmorata telangiectatica congenita (Orphanet:1556)
Developmental malformations - deafness - dystonia (Orphanet:79107)
Diastrophic dwarfism (Orphanet:628)
Distal 22q11.2 microduplication syndrome (Orphanet:261337)
Distal monosomy 6p (Orphanet:96125)
EEC syndrome (Orphanet:1896)
Ectodermal dysplasia syndrome (Orphanet:79373)
FRONTOFACIONASAL DYSPLASIA (OMIM:229400)
Feingold syndrome (Orphanet:1305)
Femoral-facial syndrome (Orphanet:1988)
Fraser syndrome (Orphanet:2052)
Fronto-facio-nasal dysostosis (Orphanet:1791)
Genito-palato-cardiac syndrome (Orphanet:2075)
German syndrome (Orphanet:2077)
Gonadal dysgenesis, XY type - associated anomalies (Orphanet:1770)
Gorlin syndrome (Orphanet:377)
HOLOPROSENCEPHALY 5 (OMIM:609637)
Holoprosencephaly (Orphanet:2162)
Holoprosencephaly - postaxial polydactyly (Orphanet:2166)
Holoprosencephaly - radial heart renal anomalies (Orphanet:3186)
Holzgreve-Wagner-Rehder syndrome (Orphanet:2167)
Hypertelorism, Teebi type (Orphanet:1519)
Hypertelorism-microtia-facial clefting syndrome (Orphanet:2213)
Hypothyroidism due to deficient transcription factors involved in pituitary development or function (Orphanet:226307)
Incontinentia pigmenti (Orphanet:464)
Iniencephaly (Orphanet:63259)
Intellectual deficit, Wolff type (Orphanet:3080)
Isotretinoin-like syndrome (Orphanet:2306)
Joubert syndrome (Orphanet:475)
Joubert syndrome with hepatic defect (Orphanet:1454)
Joubert syndrome with ocular defect (Orphanet:220493)
Joubert syndrome with renal defect (Orphanet:220497)
Juberg-Hayward syndrome (Orphanet:2319)
KERATOCONUS POSTICUS CIRCUMSCRIPTUS (OMIM:244600)
Kapur-Toriello syndrome (Orphanet:2328)
Lacrimo-auriculo-dento-digital syndrome (Orphanet:2363)
Lethal multiple pterygium syndrome (Orphanet:33108)
Lethal omphalocele-cleft palate syndrome (Orphanet:2736)
Lethal osteosclerotic bone dysplasia (Orphanet:1832)
Lymphedema - distichiasis (Orphanet:33001)
MICROCEPHALY, CORPUS CALLOSUM DYSGENESIS, AND CLEFT LIP/PALATE (OMIM:601420)
MICROPHTHALMIA, ISOLATED, WITH COLOBOMA 5 (OMIM:611638)
MICROPHTHALMIA, SYNDROMIC 1 (OMIM:309800)
MIDLINE MALFORMATIONS, MULTIPLE, WITH LIMB ABNORMALITIES AND HYPOPITUITARISM (OMIM:601016)
MMEP syndrome (Orphanet:3434)
Microphthalmia, Lenz type (Orphanet:568)
Monosomy 5p (Orphanet:281)
Mycophenolate mofetil embryopathy (Orphanet:268249)
Myhre syndrome (Orphanet:2588)
Neuralgic amyotrophy (Orphanet:2901)
OROFACIAL CLEFT 11 (OMIM:600625)
OROFACIAL CLEFT 6, SUSCEPTIBILITY TO (OMIM:608864)
Oculoauriculovertebral spectrum with radial defects (Orphanet:2549)
Oculocerebrocutaneous syndrome (Orphanet:1647)
Odontotrichomelic syndrome (Orphanet:2723)
Opitz G/BBB syndrome (Orphanet:2745)
Orofaciodigital syndrome type 4 (Orphanet:2753)
Pallister-Hall syndrome (Orphanet:672)
Peters-plus syndrome (Orphanet:709)
Pierre Robin syndrome - faciodigital anomaly (Orphanet:2888)
Postaxial acrofacial dysostosis (Orphanet:246)
RADIUS, APLASIA OF, WITH CLEFT LIP/PALATE (OMIM:179400)
Recombinant 8 syndrome (Orphanet:96167)
Roberts syndrome (Orphanet:3103)
Rothmund-Thomson syndrome (Orphanet:2909)
Short stature - intellectual deficit - eye anomalies - cleft lip/palate (Orphanet:2649)
Short-rib thoracic dysplasia 10 with or without polydactyly (OMIM:615630)
Solitary median maxillary central incisor syndrome (Orphanet:2286)
Tetraamelia - multiple malformations (Orphanet:3301)
Thomas syndrome (Orphanet:3316)
Tricho-oculo-dermo-vertebral syndrome (Orphanet:3354)
Trisomy 8q (Orphanet:1752)
Uveal coloboma - cleft lip and palate - intellectual deficit (Orphanet:1473)
Van der Woude syndrome (Orphanet:888)
Waardenburg syndrome (Orphanet:3440)
Waardenburg syndrome type 1 (Orphanet:894)
Wolf-Hirschhorn syndrome (Orphanet:280)
X-linked lethal multiple pterygium syndrome (Orphanet:79447)