Symptom Information: Sort according to HPO 

1
 (HPO:0000457) Depressed nasal ridge Frequent [Orphanet] 85 / 7739
2
 (HPO:0001513) Obesity Frequent [Orphanet] 172 / 7739
3
 (HPO:0000158) Macroglossia Frequent [Orphanet] 119 / 7739
4
 (HPO:0010808) Protruding tongue 28 / 7739
5
 (HPO:0001252) Muscular hypotonia Very frequent [Orphanet] 990 / 7739
6
 (HPO:0000789) Infertility Frequent [Orphanet] 74 / 7739
7
 (HPO:0000160) Narrow mouth Frequent [Orphanet] 188 / 7739
8
 (HPO:0002488) Acute leukemia Occasional [Orphanet] 29 / 7739
9
 (HPO:0000164) Abnormality of the teeth Frequent [Orphanet] 291 / 7739
10
 (HPO:0000474) Thickened nuchal skin fold 10 / 7739
11
 (HPO:0005989) Redundant neck skin Very frequent [Orphanet] 40 / 7739
12
 (HPO:0000405) Conductive hearing impairment Occasional [Orphanet] 164 / 7739
13
 (HPO:0000545) Myopia Occasional [Orphanet] 286 / 7739
14
 (HPO:0002023) Anal atresia Occasional [Orphanet] 135 / 7739
15
 (HPO:0001852) Sandal gap Frequent [Orphanet] 63 / 7739
16
 (HPO:0000691) Microdontia Frequent [Orphanet] 104 / 7739
17
 (HPO:0007021) Pain insensitivity Occasional [Orphanet] 35 / 7739
18
 (HPO:0005978) Type II diabetes mellitus Occasional [Orphanet] 68 / 7739
19
 (HPO:0002705) High, narrow palate Frequent [Orphanet] 308 / 7739
20
 (HPO:0030680) Abnormality of cardiovascular system morphology Frequent [Orphanet] 355 / 7739
21
 (HPO:0000582) Upslanted palpebral fissure Very frequent [Orphanet] 185 / 7739
22
 (HPO:0005280) Depressed nasal bridge Very frequent [Orphanet] 381 / 7739
23
 (HPO:0000248) Brachycephaly Very frequent [Orphanet] 222 / 7739
24
 (HPO:0000239) Large fontanelles Frequent [Orphanet] 135 / 7739
25
 (HPO:0007495) Prematurely aged appearance Frequent [Orphanet] 44 / 7739
26
 (HPO:0100830) Round ear Very frequent [Orphanet] 7 / 7739
27
 (HPO:0000518) Cataract Occasional [Orphanet] 454 / 7739
28
 (HPO:0000470) Short neck Very frequent [Orphanet] 345 / 7739
29
 (HPO:0004209) Clinodactyly of the 5th finger Frequent [Orphanet] 288 / 7739
30
 (HPO:0000821) Hypothyroidism Occasional [Orphanet] 141 / 7739
31
 (HPO:0001537) Umbilical hernia Frequent [Orphanet] 206 / 7739
32
 (HPO:0001288) Gait disturbance Occasional [Orphanet] 318 / 7739
33
 (HPO:0003196) Short nose Frequent [Orphanet] 264 / 7739
34
 (HPO:0100763) Abnormality of the lymphatic system Frequent [Orphanet] 18 / 7739
35
 (HPO:0000954) Single transverse palmar crease Frequent [Orphanet] 162 / 7739
36
 (HPO:0001006) Hypotrichosis Occasional [Orphanet] 219 / 7739
37
 (HPO:0000486) Strabismus Occasional [Orphanet] 576 / 7739
38
 (HPO:0002714) Downturned corners of mouth Frequent [Orphanet] 98 / 7739
39
 (HPO:0000194) Open mouth Frequent [Orphanet] 70 / 7739
40
 (HPO:0002250) Abnormality of the large intestine Occasional [Orphanet] 32 / 7739
41
 (HPO:0004279) Short palm Very frequent [Orphanet] 323 / 7739
42
 (HPO:0000286) Epicanthus Very frequent [Orphanet] 371 / 7739
43
 (HPO:0001382) Joint hypermobility Very frequent [Orphanet] 231 / 7739
44
 (HPO:0001388) Joint laxity 117 / 7739
45
 (HPO:0001249) Intellectual disability 1089 / 7739
46
 (HPO:0012368) Flat face Very frequent [Orphanet] 106 / 7739
47
 (HPO:0001088) Brushfield spots 8 / 7739
48
 (HPO:0001169) Broad palm 43 / 7739
49
 (HPO:0001674) Complete atrioventricular canal defect 11 / 7739
50
 (HPO:0002251) Aganglionic megacolon 78 / 7739
51
 (HPO:0002511) Alzheimer disease 10 / 7739
52
 (HPO:0002866) Hypoplastic iliac wing 34 / 7739
53
 (HPO:0003182) Shallow acetabular fossae 10 / 7739
54
 (HPO:0003467) Atlantoaxial instability 6 / 7739
55
 (HPO:0004220) Short middle phalanx of the 5th finger 17 / 7739
56
 (HPO:0004322) Short stature 1232 / 7739
57
 (HPO:0006733) Acute megakaryocytic leukemia 1 / 7739
58
 (HPO:0008551) Microtia 98 / 7739
59
 (HPO:0008678) Renal hypoplasia/aplasia Occasional [Orphanet] 127 / 7739
60
 (HPO:0010978) Abnormality of immune system physiology Frequent [Orphanet] 148 / 7739
61
 (HPO:0100867) Duodenal stenosis 29 / 7739
62
 (OMIM) Flat facial profile 6 / 7739
63
 (HPO:0000396) Overfolded helix 21 / 7739
64
 (OMIM) Broad, short hands 14 / 7739
65
 (OMIM) Hypotonia, poor Moro reflex 1 / 7739
66
 (OMIM) Leukemoid reactions 1 / 7739
67
 (HPO:0001909) Leukemia 46 / 7739
68
 (HPO:0001428) Somatic mutation Very frequent [Orphanet] 100 / 7739
69
 (HPO:0012758) Neurodevelopmental delay Very frequent [Orphanet] 949 / 7739
70
 (HPO:0012471) Thick vermilion border Frequent [Orphanet] 115 / 7739
71
 (HPO:0100543) Cognitive impairment Frequent [Orphanet] 230 / 7739
72
 (HPO:0000272) Malar flattening 277 / 7739
73
 (HPO:0003745) Sporadic 131 / 7739
74
 (HPO:0005547) Myeloproliferative disorder 7 / 7739