Pain insensitivity

Symptom Information:

Symptom ID: HPO:0007021
Synonyms:
Absence of pain sensation [HPO:0007021]
Insensitivity to pain [Orphanet:43410]
Pain insensitivity [OMIM:Pain insensitivity]
Insensitivity to pain [OMIM:Insensitivity to pain]
Quality:
Cross references:
HPO:0007328 "Impaired pain sensation" [Orphanet:43410]
Orphanet:43410 "Insensitivity to pain" [Orphanet:43410]
OMIM: "Pain insensitivity" [OMIM:Pain insensitivity]
OMIM: "Insensitivity to pain" [OMIM:Insensitivity to pain]
Is a (Direct Parents):
HPO         Impaired pain sensation
Orphanet Sensitive trouble/deficit
Is a (Whole tree): HPO:
All(HPO:0000001)
    Phenotypic abnormality(HPO:0000118)
       Abnormality of the nervous system(HPO:0000707)
          Abnormality of nervous system morphology(HPO:0012639)
             Abnormal peripheral nervous system morphology(HPO:0000759)
                Peripheral neuropathy(HPO:0009830)
                   Sensory impairment(HPO:0003474)
                      Abnormality of pain sensation(HPO:0010832)
                         Impaired pain sensation(HPO:0007328)
                            Pain insensitivity(HPO:0007021)
MedDRA:
Database Frequency: 35 / 7739
Resource:

All diseases associated with this symptom:

16p11.2p12.2 microdeletion syndrome (Orphanet:261211)
2q37 microdeletion syndrome (Orphanet:1001)
Autosomal dominant cerebellar ataxia (Orphanet:99)
Autosomal dominant optic atrophy plus syndrome (Orphanet:1215)
Channelopathy-associated congenital insensitivity to pain (Orphanet:88642)
Charcot-Marie-Tooth disease (Orphanet:166)
Down syndrome (Orphanet:870)
Familial dysautonomia (Orphanet:1764)
Flynn-Aird syndrome (Orphanet:2047)
Gemignani syndrome (Orphanet:2074)
Gómez-López-Hernández syndrome (Orphanet:1532)
Hemihypertrophy (Orphanet:2128)
Hereditary sensory and autonomic neuropathy type 4 (Orphanet:642)
Hereditary sensory and autonomic neuropathy type 5 (Orphanet:64752)
Hereditary sensory and autonomic neuropathy with spastic paraplegia (Orphanet:139578)
Hereditary spastic paraplegia (Orphanet:685)
INDIFFERENCE TO PAIN, CONGENITAL, AUTOSOMAL DOMINANT (OMIM:147430)
INSENSITIVITY TO PAIN WITH HYPERPLASTIC MYELINOPATHY (OMIM:147530)
Infantile axonal neuropathy (Orphanet:2679)
Monosomy 22q13 (Orphanet:48652)
Myalgia-eosinophilia syndrome associated with tryptophan (Orphanet:2582)
NEUROPATHY, HEREDITARY SENSORY AND AUTONOMIC, TYPE VII (OMIM:615548)
Navajo neurohepatopathy (Orphanet:255229)
Polyneuropathy - hand defect (Orphanet:2926)
Smith-Magenis syndrome (Orphanet:819)
Spastic paraparesis - deafness (Orphanet:2815)
Stiff skin syndrome (Orphanet:2833)
Stüve-Wiedemann syndrome (Orphanet:3206)
Tangier disease (Orphanet:31150)
Van Regemorter-Pierquin-Vamos syndrome (Orphanet:3419)
X-linked Charcot-Marie-Tooth disease type 1 (Orphanet:101075)
X-linked Charcot-Marie-Tooth disease type 2 (Orphanet:101076)
X-linked Charcot-Marie-Tooth disease type 3 (Orphanet:101077)
X-linked Charcot-Marie-Tooth disease type 4 (Orphanet:101078)
X-linked Charcot-Marie-Tooth disease type 5 (Orphanet:99014)