Decreased testicular size

Symptom Information:

Symptom ID: HPO:0008734
Synonyms:
Hypoplastic testes [HPO:0008734]
Small testes [HPO:0008734]
Testicular hypoplasia [HPO:0008734]
Small testis [Orphanet:39400]
Congenital hypoplasia of testis (disorder) [Orphanet:39400]
Atrophy of testis (disorder) [Orphanet:39400]
Small testicle (finding) [Orphanet:39400]
Small testicle [Orphanet:39400]
Congenital hypoplasia of testis [Orphanet:39400]
Atrophy of testis [Orphanet:39400]
Decreased testicular size [OMIM:Decreased testicular size]
Hypoplastic testes [OMIM:Hypoplastic testes]
Small testes [OMIM:Small testes]
Testicular hypoplasia [OMIM:Testicular hypoplasia]
Small/atrophic/hypoplastic testes/monorchism/microorchidism/anorchia [Orphanet:39400]
Testicular atrophy [Orphanet:39400]
Testicular hypoplasia [Orphanet:39400]
Testicular atrophy [MedDRA:10043298]
Atrophy of testis [MedDRA:10043298]
Atrophy testicular [MedDRA:10043298]
Orchiatrophy [MedDRA:10043298]
Reproductive tract hypoplasia, male [MedDRA:10057858]
Testicular hypoplasia [MedDRA:10057858]
Hypoplastic scrotum [MedDRA:10057858]
Small testes (in some patients) [OMIM:Small testes (in some patients)]
Small testicles (1 patient) [OMIM:Small testicles (1 patient)]
Small testicles (in some patients) [OMIM:Small testicles (in some patients)]
Testicular atrophy (in a subset of patients) [OMIM:Testicular atrophy (in a subset of patients)]
Testicular hypoplasia (1 patient) [OMIM:Testicular hypoplasia (1 patient)]
Monorchidism [MedDRA:10055002]
Monorchism [Orphanet:39400]
Monorchism (disorder) [Orphanet:39400]
Quality:
Cross references:
Orphanet:39400 "Small/atrophic/hypoplastic testes/monorchism/microorchidism/anorchia" [Orphanet:39400]
OMIM: "Decreased testicular size" [OMIM:Decreased testicular size]
OMIM: "Hypoplastic testes" [OMIM:Hypoplastic testes]
OMIM: "Small testes" [OMIM:Small testes]
OMIM: "Testicular hypoplasia" [OMIM:Testicular hypoplasia]
OMIM: "Small testes (in some patients)" [OMIM:Small testes (in some patients)]
OMIM: "Small testicles (1 patient)" [OMIM:Small testicles (1 patient)]
OMIM: "Small testicles (in some patients)" [OMIM:Small testicles (in some patients)]
OMIM: "Testicular atrophy (in a subset of patients)" [OMIM:Testicular atrophy (in a subset of patients)]
OMIM: "Testicular hypoplasia (1 patient)" [OMIM:Testicular hypoplasia (1 patient)]
UMLS:C0241355 "Small testicle" [Orphanet:39400]
UMLS:C0266425 "Congenital hypoplasia of testis" [Orphanet:39400]
UMLS:C0156312 "Atrophy of testis" [Orphanet:39400]
UMLS:C0266429 "Monorchism" [Orphanet:39400]
Is a (Direct Parents):
HPO         Hypoplastic male external genitalia
Orphanet Abnormality of the testis
MedDRA Testicular and epididymal disorders NEC
HPO         Aplasia/Hypoplasia of the testes
MedDRA Male reproductive tract disorders congenital
Is a (Whole tree): HPO:
All(HPO:0000001)
    Phenotypic abnormality(HPO:0000118)
       Abnormality of the genitourinary system(HPO:0000119)
          Abnormality of the genital system(HPO:0000078)
             Abnormal genital system morphology(HPO:0012243)
                Abnormality of the male genitalia(HPO:0010461)
                   Abnormality of male internal genitalia(HPO:0000022)
                      Abnormality of the testis(HPO:0000035)
                         Aplasia/Hypoplasia of the testes(HPO:0010468)
                            Decreased testicular size(HPO:0008734)
                   Abnormality of male external genitalia(HPO:0000032)
                      Hypoplastic male external genitalia(HPO:0000050)
                         Decreased testicular size(HPO:0008734)
                Abnormal internal genitalia(HPO:0000812)
                   Abnormality of male internal genitalia(HPO:0000022)
                      Abnormality of the testis(HPO:0000035)
                         Aplasia/Hypoplasia of the testes(HPO:0010468)
                            Decreased testicular size(HPO:0008734)
                Abnormal external genitalia(HPO:0000811)
                   External genital hypoplasia(HPO:0003241)
                      Hypoplastic male external genitalia(HPO:0000050)
                         Decreased testicular size(HPO:0008734)
                   Abnormality of male external genitalia(HPO:0000032)
                      Hypoplastic male external genitalia(HPO:0000050)
                         Decreased testicular size(HPO:0008734)
MedDRA:
Reproductive system and breast disorders(MedDRA:10038604)
    Testicular and epididymal disorders(MedDRA:10013362)
       Testicular and epididymal disorders NEC(MedDRA:10043296)
          Decreased testicular size(HPO:0008734)
Congenital, familial and genetic disorders(MedDRA:10010331)
    Reproductive tract and breast disorders congenital(MedDRA:10038608)
       Male reproductive tract disorders congenital(MedDRA:10025517)
          Decreased testicular size(HPO:0008734)
Database Frequency: 105 / 7739
Resource:

All diseases associated with this symptom:

2p15p16.1 microdeletion syndrome (Orphanet:261349)
2q32q33 microdeletion syndrome (Orphanet:251019)
3-phosphoglycerate dehydrogenase deficiency (Orphanet:79351)
3M syndrome (Orphanet:2616)
3q13 microdeletion syndrome (Orphanet:1621)
46,XX testicular disorder of sex development (Orphanet:393)
46,XY complete gonadal dysgenesis (Orphanet:242)
48,XXXY syndrome (Orphanet:96263)
48,XXYY syndrome (Orphanet:10)
49,XXXXY syndrome (Orphanet:96264)
Acrodermatitis enteropathica, zinc deficiency type (Orphanet:37)
Alopecia - intellectual deficit - hypergonadotropic hypogonadism (Orphanet:1014)
Alström syndrome (Orphanet:64)
Aromatase deficiency (Orphanet:91)
Ataxia-telangiectasia (Orphanet:100)
Autosomal recessive spastic paraplegia type 46 (Orphanet:320391)
BRESEK syndrome (Orphanet:85284)
Bangstad syndrome (Orphanet:1227)
Bardet-Biedl syndrome (Orphanet:110)
Borjeson-Forssman-Lehmann syndrome (Orphanet:127)
Brachydactyly - nystagmus - cerebellar ataxia (Orphanet:1246)
Cabezas syndrome (Orphanet:85293)
Carpenter-Waziri syndrome (Orphanet:93973)
Caudal appendage - deafness (Orphanet:1123)
Chudley-Lowry-Hoar syndrome (Orphanet:93971)
Congenital adrenal hyperplasia due to 11-beta-hydroxylase deficiency (Orphanet:90795)
Congenital cataracts - facial dysmorphism - neuropathy (Orphanet:48431)
Congenital ichthyosis - intellectual deficit - spastic quadriplegia (Orphanet:352333)
Congenital muscular dystrophy - infantile cataract - hypogonadism (Orphanet:1875)
Crandall syndrome (Orphanet:202)
Cryptorchidism - arachnodactyly - intellectual deficit (Orphanet:1548)
Diabetic embryopathy (Orphanet:1926)
Dilated cardiomyopathy with ataxia (Orphanet:66634)
Dyskeratosis congenita (Orphanet:1775)
Erythrokeratodermia variabilis (Orphanet:317)
Fanconi anemia (Orphanet:84)
Gemignani syndrome (Orphanet:2074)
Genito-palato-cardiac syndrome (Orphanet:2075)
HYPOGONADOTROPIC HYPOGONADISM 11 WITH OR WITHOUT ANOSMIA (OMIM:614840)
HYPOGONADOTROPIC HYPOGONADISM 12 WITH OR WITHOUT ANOSMIA (OMIM:614841)
HYPOGONADOTROPIC HYPOGONADISM 14 WITH OR WITHOUT ANOSMIA (OMIM:614858)
HYPOGONADOTROPIC HYPOGONADISM 15 WITH OR WITHOUT ANOSMIA (OMIM:614880)
HYPOGONADOTROPIC HYPOGONADISM 16 WITH OR WITHOUT ANOSMIA (OMIM:614897)
HYPOGONADOTROPIC HYPOGONADISM 22 WITH OR WITHOUT ANOSMIA (OMIM:616030)
HYPOGONADOTROPIC HYPOGONADISM 4 WITH OR WITHOUT ANOSMIA (OMIM:610628)
HYPOGONADOTROPIC HYPOGONADISM 7 WITH OR WITHOUT ANOSMIA (OMIM:146110)
HYPOGONADOTROPIC HYPOGONADISM 8 WITH OR WITHOUT ANOSMIA (OMIM:614837)
Holmes-Gang syndrome (Orphanet:93970)
Hoyeraal-Hreidarsson syndrome (Orphanet:3322)
Hypergonadotropic hypogonadism - cataract syndrome (Orphanet:2410)
Hypogonadism - mitral valve prolapse - intellectual deficit (Orphanet:2233)
Hypogonadotropic hypogonadism - frontoparietal alopecia (Orphanet:2230)
Intellectual deficit - cataracts - calcified pinnae - myopathy (Orphanet:3042)
Intellectual deficit - dysmorphism - hypogonadism - diabetes mellitus (Orphanet:3044)
Intellectual deficit, X-linked - short stature - obesity (Orphanet:3055)
Intellectual deficit, X-linked, Abidi type (Orphanet:85273)
Intellectual deficit, X-linked, Siderius type (Orphanet:85287)
Isolated follicle stimulating hormone deficiency (Orphanet:52901)
Juberg-Marsidi syndrome (Orphanet:93972)
Kallmann syndrome (Orphanet:478)
Kennedy disease (Orphanet:481)
MENTAL RETARDATION, X-LINKED 92 (OMIM:300851)
MUSCULAR DYSTROPHY-DYSTROGLYCANOPATHY (CONGENITAL WITH BRAIN AND EYEANOMALIES), TYPE A, 13 (OMIM:615287)
MYELODYSPLASIA, IMMUNODEFICIENCY, FACIAL DYSMORPHISM, SHORT STATURE,AND PSYCHOMOTOR DELAY (OMIM:601347)
Male hypergonadotropic hypogonadism - intellectual deficit - skeletal anomalies (Orphanet:2234)
Mikati-Najjar-Sahli syndrome (Orphanet:2558)
Moebius syndrome (Orphanet:570)
Monosomy 18p (Orphanet:1598)
Mosaic trisomy 8 (Orphanet:96061)
Moyamoya disease - short stature - facial dysmorphism - hypergonadotropic hypogonadism (Orphanet:280679)
Neuroectodermal syndrome, Johnson type (Orphanet:2316)
Normosmic congenital hypogonadotropic hypogonadism (Orphanet:432)
Obesity due to congenital leptin deficiency (Orphanet:66628)
Orofaciodigital syndrome type 4 (Orphanet:2753)
PAGOD syndrome (Orphanet:991)
PREMATURE OVARIAN FAILURE 10 (OMIM:612885)
PROGRESSIVE EXTERNAL OPHTHALMOPLEGIA WITH MITOCHONDRIAL DNA DELETIONS,AUTOSOMAL DOMINANT, 1 (OMIM:157640)
Pallister-Hall syndrome (Orphanet:672)
Primary hypergonadotropic hypogonadism - partial alopecia (Orphanet:2232)
Prune belly syndrome (Orphanet:2970)
Renier-Gabreels-Jasper syndrome (Orphanet:93975)
Renpenning syndrome (Orphanet:3242)
Retinitis pigmentosa (Orphanet:791)
Retinitis pigmentosa - intellectual deficit - deafness - hypogenitalism (Orphanet:3085)
Retinohepatoendocrinologic syndrome (Orphanet:3087)
Say-Barber-Miller syndrome (Orphanet:3132)
Schwartz-Jampel syndrome (Orphanet:800)
Smith-Fineman-Myers syndrome (Orphanet:93974)
Steinert myotonic dystrophy (Orphanet:273)
Syndromic X-linked intellectual deficit due to JARID1C mutation (Orphanet:85279)
TEMPLE SYNDROME (OMIM:616222)
TESTES, RUDIMENTARY (OMIM:273150)
THREE M SYNDROME 1 (OMIM:273750)
Tel Hashomer camptodactyly syndrome (Orphanet:3292)
Testicular regression syndrome (Orphanet:983)
Testotoxicosis (Orphanet:3000)
WARBURG MICRO SYNDROME 3 (OMIM:614222)
WARBURG MICRO SYNDROME 4 (OMIM:615663)
Werner syndrome (Orphanet:902)
Wilson-Turner syndrome (Orphanet:3459)
Woodhouse-Sakati syndrome (Orphanet:3464)
X-linked intellectual deficit - hypotonic face (Orphanet:73220)
X-linked lissencephaly with abnormal genitalia (Orphanet:452)
Xeroderma pigmentosum (Orphanet:910)
Xq27.3q28 duplication syndrome (Orphanet:261483)