IgA deficiency

Symptom Information:

Symptom ID: HPO:0002720
Synonyms:
Decreased IgA [HPO:0002720]
Decreased immunoglobulin A [HPO:0002720]
Gamma-A globulin deficiency [HPO:0002720]
Low levels of immunoglobulin A [HPO:0002720]
Reduced IgA levels [HPO:0002720]
Decreased IgA [OMIM:Decreased IgA]
Gamma-A globulin deficiency [OMIM:Gamma-A globulin deficiency]
IgA deficiency [OMIM:IgA deficiency]
Low levels of immunoglobulin A [OMIM:Low levels of immunoglobulin A]
Reduced IgA levels [OMIM:Reduced IgA levels]
Decreased immunoglobulin A (IgA) [OMIM:Decreased immunoglobulin A (IgA)]
Quality:
Cross references:
OMIM: "Decreased IgA" [OMIM:Decreased IgA]
OMIM: "Gamma-A globulin deficiency" [OMIM:Gamma-A globulin deficiency]
OMIM: "IgA deficiency" [OMIM:IgA deficiency]
OMIM: "Low levels of immunoglobulin A" [OMIM:Low levels of immunoglobulin A]
OMIM: "Reduced IgA levels" [OMIM:Reduced IgA levels]
OMIM: "Decreased immunoglobulin A (IgA)" [OMIM:Decreased immunoglobulin A (IgA)]
Is a (Direct Parents):
HPO         Decreased antibody level in blood
Is a (Whole tree): HPO:
All(HPO:0000001)
    Phenotypic abnormality(HPO:0000118)
       Abnormality of the immune system(HPO:0002715)
          Abnormality of cellular immune system(HPO:0010987)
             Abnormality of leukocytes(HPO:0001881)
                Abnormality of lymphocytes(HPO:0004332)
                   Abnormality of B cells(HPO:0002846)
                      Abnormality of B cell physiology(HPO:0005372)
                         Abnormal immunoglobulin level(HPO:0010701)
                            Decreased antibody level in blood(HPO:0004313)
                               IgA deficiency(HPO:0002720)
          Abnormality of immune system physiology(HPO:0010978)
             Abnormality of humoral immunity(HPO:0005368)
                Abnormal immunoglobulin level(HPO:0010701)
                   Decreased antibody level in blood(HPO:0004313)
                      IgA deficiency(HPO:0002720)
       Abnormality of blood and blood-forming tissues(HPO:0001871)
          Abnormality of leukocytes(HPO:0001881)
             Abnormality of lymphocytes(HPO:0004332)
                Abnormality of B cells(HPO:0002846)
                   Abnormality of B cell physiology(HPO:0005372)
                      Abnormal immunoglobulin level(HPO:0010701)
                         Decreased antibody level in blood(HPO:0004313)
                            IgA deficiency(HPO:0002720)
MedDRA:
Database Frequency: 33 / 7739
Resource:

All diseases associated with this symptom:

ATAXIA-TELANGIECTASIA (OMIM:208900)
ATAXIA-TELANGIECTASIA WITH GENERALIZED SKIN PIGMENTATION AND EARLYDEATH (OMIM:208910)
Ataxia-telangiectasia (Orphanet:100)
Autoinflammation and PLCG2-associated antibody deficiency and immune dysregulation (Orphanet:324530)
Bloom syndrome (Orphanet:125)
CELIAC DISEASE, SUSCEPTIBILITY TO, 1 (OMIM:212750)
CHONDROITIN-6-SULFATURIA, DEFECTIVE CELLULAR IMMUNITY, NEPHROTIC SYNDROME (OMIM:215250)
Common variable immunodeficiency (Orphanet:1572)
Dubowitz syndrome (Orphanet:235)
GAMMA-A-GLOBULIN, DEFECT IN ASSEMBLY OF (OMIM:137050)
Generalized congenital lipodystrophy with myopathy (Orphanet:228429)
HEMOSIDEROSIS, PULMONARY, WITH DEFICIENCY OF GAMMA-A GLOBULIN (OMIM:235500)
Hyper-IgM syndrome type 2 (Orphanet:101089)
Hyper-IgM syndrome type 3 (Orphanet:101090)
Hyper-IgM syndrome type 5 (Orphanet:101092)
IMMUNE DEFICIENCY, FAMILIAL VARIABLE (OMIM:146830)
IMMUNODEFICIENCY WITHOUT ANHIDROTIC ECTODERMAL DYSPLASIA (OMIM:300584)
IMMUNODEFICIENCY, COMMON VARIABLE, 1 (OMIM:607594)
IMMUNODEFICIENCY, COMMON VARIABLE, 2 (OMIM:240500)
IMMUNODEFICIENCY, COMMON VARIABLE, 7 (OMIM:614699)
IMMUNODEFICIENCY, COMMON VARIABLE, 8, WITH AUTOIMMUNITY (OMIM:614700)
IMMUNOGLOBULIN A DEFICIENCY 1 (OMIM:137100)
IMMUNOGLOBULIN A DEFICIENCY 2 (OMIM:609529)
Immunodeficiency due to CD25 deficiency (Orphanet:169100)
Lichstenstein syndrome (Orphanet:2390)
Lung fibrosis - immunodeficiency - 46,XX gonadal dysgenesis (Orphanet:137631)
MENTAL RETARDATION, X-LINKED, SYNDROMIC, CHUDLEY-SCHWARTZ TYPE (OMIM:300861)
Monosomy 18q (Orphanet:1600)
PMM2-CDG (Orphanet:79318)
Polyarteritis nodosa, childhood-onset (OMIM:615688)
Severe combined immunodeficiency due to adenosine deaminase deficiency (Orphanet:277)
Transcobalamin deficiency (Orphanet:859)
X-linked hyper-IgM syndrome (Orphanet:101088)