Decreased antibody level in blood

Symptom Information:

Symptom ID: HPO:0004313
Synonyms:
Decreased immunoglobulin level [HPO:0004313]
Decreased serum immunoglobulin [HPO:0004313]
Immunoglobulin deficiency [HPO:0004313]
Reduced immunoglobulin levels [HPO:0004313]
Hypogammaglobulinemia (finding) [Orphanet:47160]
Hypogammaglobulinemia [Orphanet:47160]
Decreased serum immunoglobulin [OMIM:Decreased serum immunoglobulin]
Hypogammaglobulinemia [OMIM:Hypogammaglobulinemia]
Agammaglobulinemia/hypogammaglobulinemia/B-cell deficiency [Orphanet:47160]
Hypogammaglobulinaemia [Orphanet:47160]
Hypogammaglobulinaemia [MedDRA:10020983]
Agammaglobulinaemia [MedDRA:10020983]
Agammaglobulinemia [MedDRA:10020983]
Hypogammaglobulinaemia NOS [MedDRA:10020983]
Hypogammaglobulinemia, unspecified [MedDRA:10020983]
Other selective immunoglobulin deficiencies [MedDRA:10020983]
Physiologic hypogammaglobulinemia [MedDRA:10020983]
Hypogammaglobulinemia [MedDRA:10020983]
Hypogammaglobulinaemia, unspecified [MedDRA:10020983]
Physiologic hypogammaglobulinaemia [MedDRA:10020983]
Panhypogammaglobulinaemia [MedDRA:10020983]
Panhypogammaglobulinemia [MedDRA:10020983]
Decreased serum immunoglobulins [OMIM:Decreased serum immunoglobulins]
Hypogammaglobulinemia (1 patient) [OMIM:Hypogammaglobulinemia (1 patient)]
Immunoglobulin deficiency (IgA, IgG, IgM) [OMIM:Immunoglobulin deficiency (IgA, IgG, IgM)]
Humoral immune defect [MedDRA:10020464]
Humoral immune deficiency [Orphanet:47160]
Humoral immune defect (finding) [Orphanet:47160]
Deficiencies of humoral immunity (finding) [Orphanet:47160]
Humoral immune defect [Orphanet:47160]
Quality:
Cross references:
Orphanet:47160 "Agammaglobulinemia/hypogammaglobulinemia/B-cell deficiency" [Orphanet:47160]
OMIM: "Decreased serum immunoglobulin" [OMIM:Decreased serum immunoglobulin]
OMIM: "Hypogammaglobulinemia" [OMIM:Hypogammaglobulinemia]
OMIM: "Decreased serum immunoglobulins" [OMIM:Decreased serum immunoglobulins]
OMIM: "Hypogammaglobulinemia (1 patient)" [OMIM:Hypogammaglobulinemia (1 patient)]
OMIM: "Immunoglobulin deficiency (IgA, IgG, IgM)" [OMIM:Immunoglobulin deficiency (IgA, IgG, IgM)]
UMLS:C0086438 "Hypogammaglobulinemia" [Orphanet:47160]
UMLS:C0522274 "Humoral immune defect" [Orphanet:47160]
Is a (Direct Parents):
Orphanet Recurrent bacterial infections
MedDRA Primary immunodeficiency syndromes
HPO         Abnormal immunoglobulin level
Is a (Whole tree): HPO:
All(HPO:0000001)
    Phenotypic abnormality(HPO:0000118)
       Abnormality of blood and blood-forming tissues(HPO:0001871)
          Abnormality of leukocytes(HPO:0001881)
             Abnormality of lymphocytes(HPO:0004332)
                Abnormality of B cells(HPO:0002846)
                   Abnormality of B cell physiology(HPO:0005372)
                      Abnormal immunoglobulin level(HPO:0010701)
                         Decreased antibody level in blood(HPO:0004313)
       Abnormality of the immune system(HPO:0002715)
          Abnormality of cellular immune system(HPO:0010987)
             Abnormality of leukocytes(HPO:0001881)
                Abnormality of lymphocytes(HPO:0004332)
                   Abnormality of B cells(HPO:0002846)
                      Abnormality of B cell physiology(HPO:0005372)
                         Abnormal immunoglobulin level(HPO:0010701)
                            Decreased antibody level in blood(HPO:0004313)
          Abnormality of immune system physiology(HPO:0010978)
             Abnormality of humoral immunity(HPO:0005368)
                Abnormal immunoglobulin level(HPO:0010701)
                   Decreased antibody level in blood(HPO:0004313)
MedDRA:
Immune system disorders(MedDRA:10021428)
    Immunodeficiency syndromes(MedDRA:10021460)
       Primary immunodeficiency syndromes(MedDRA:10036700)
          Decreased antibody level in blood(HPO:0004313)
Database Frequency: 47 / 7739
Resource:

All diseases associated with this symptom:

AUTOIMMUNE LYMPHOPROLIFERATIVE SYNDROME, TYPE V (OMIM:616100)
Alpha-mannosidosis (Orphanet:61)
Bloom syndrome (Orphanet:125)
CONGENITAL DISORDER OF GLYCOSYLATION, TYPE IIl (OMIM:614576)
Combined immunodeficiency with skin granulomas (Orphanet:157949)
DYSKERATOSIS CONGENITA, AUTOSOMAL RECESSIVE, 5 (OMIM:615190)
Dubowitz syndrome (Orphanet:235)
ENTEROPATHY, FAMILIAL, WITH VILLOUS EDEMA AND IMMUNOGLOBULIN G2 DEFICIENCY (OMIM:600351)
GCS1-CDG (Orphanet:79330)
GRANULOCYTOPENIA WITH IMMUNOGLOBULIN ABNORMALITY (OMIM:233600)
Hepatic veno-occlusive disease - immunodeficiency (Orphanet:79124)
ICF syndrome (Orphanet:2268)
IMMUNODEFICIENCY 14 (OMIM:615513)
IMMUNODEFICIENCY 36 (OMIM:616005)
IMMUNODEFICIENCY 37 (OMIM:616098)
IMMUNODEFICIENCY, COMMON VARIABLE, 1 (OMIM:607594)
IMMUNODEFICIENCY, COMMON VARIABLE, 10 (OMIM:615577)
IMMUNODEFICIENCY, COMMON VARIABLE, 11 (OMIM:615767)
IMMUNODEFICIENCY, COMMON VARIABLE, 2 (OMIM:240500)
IMMUNODEFICIENCY, COMMON VARIABLE, 3 (OMIM:613493)
IMMUNODEFICIENCY, COMMON VARIABLE, 4 (OMIM:613494)
IMMUNODEFICIENCY, COMMON VARIABLE, 5 (OMIM:613495)
IMMUNODEFICIENCY, COMMON VARIABLE, 6 (OMIM:613496)
IMMUNODEFICIENCY, COMMON VARIABLE, 7 (OMIM:614699)
IMMUNODEFICIENCY, COMMON VARIABLE, 8, WITH AUTOIMMUNITY (OMIM:614700)
IMMUNODEFICIENCY, PARTIAL COMBINED, WITH ABSENCE OF HLA DETERMINANTSAND BETA-2-MICROGLOBULIN FROM LYMPHOCYTES (OMIM:242870)
IMMUNODEFICIENCY-CENTROMERIC INSTABILITY-FACIAL ANOMALIES SYNDROME2 (OMIM:614069)
IMMUNOERYTHROMYELOID HYPOPLASIA (OMIM:242880)
Intestinal lymphangiectasia (Orphanet:36204)
LEUKOENCEPHALOPATHY, ARTHRITIS, COLITIS, AND HYPOGAMMAGLOBULINEMA (OMIM:608809)
LYMPHOPROLIFERATIVE SYNDROME 1 (OMIM:613011)
LYMPHOPROLIFERATIVE SYNDROME 2 (OMIM:615122)
Lymphoid interstitial pneumonia (Orphanet:79128)
Osteopetrosis - hypogammaglobulinemia (Orphanet:178389)
Polyarteritis nodosa, childhood-onset (OMIM:615688)
Primary intestinal lymphangiectasia (Orphanet:90362)
RETINAL TELANGIECTASIA AND HYPOGAMMAGLOBULINEMIA (OMIM:267900)
SIDEROBLASTIC ANEMIA WITH B-CELL IMMUNODEFICIENCY, PERIODIC FEVERS,AND DEVELOPMENTAL DELAY (OMIM:616084)
SPONASTRIME dysplasia (Orphanet:93357)
Severe combined immunodeficiency due to CARD11 deficiency (Orphanet:357237)
Severe combined immunodeficiency due to adenosine deaminase deficiency (Orphanet:277)
TRICHOTHIODYSTROPHY, PHOTOSENSITIVE (OMIM:601675)
Thrombocytopenia - absent radius (Orphanet:3320)
Vici syndrome (Orphanet:1493)
WHIM syndrome (Orphanet:51636)
Wolfram syndrome 2 (OMIM:604928)
X-linked lymphoproliferative disease (Orphanet:2442)