Lymphoid interstitial pneumonia

General Information (adopted from Orphanet):

Synonyms, Signs: LIP
Lymphocytic interstitial pneumonia
Number of Symptoms 45
OrphanetNr: 79128
OMIM Id: 247610
ICD-10: J84.1
UMLs: C0264511
MeSH:
MedDRA: 10062997
Snomed: 44274007

Prevalence, inheritance and age of onset:

Prevalence: No data available.
Inheritance:
Age of onset:

Disease classification (adopted from Orphanet):

Parent Diseases: Idiopathic interstitial pneumonia
 -Rare respiratory disease

Comment:

The disease usually shows good response to combinative therapy of corticosteroids and cytotoxic agents. (PMID:19040067)

Symptom Information: Sort by abundance 

1
 (HPO:0012378) Fatigue 7360539 IBIS 50 / 7739
2
 (HPO:0100759) Clubbing of fingers 7360539 IBIS 40 / 7739
3
 (HPO:0100749) Chest pain 3453998 IBIS 92 / 7739
4
 (HPO:0001217) Clubbing 1907689 IBIS 39 / 7739
5
 (HPO:0002240) Hepatomegaly 7360539 IBIS 467 / 7739
6
 (HPO:0002613) Biliary cirrhosis 3453998 IBIS 11 / 7739
7
 (HPO:0012115) Hepatitis 3453998 IBIS 24 / 7739
8
 (HPO:0001508) Failure to thrive 9361104 IBIS 454 / 7739
9
 (HPO:0000961) Cyanosis 7360539 IBIS 60 / 7739
10
 (HPO:0001640) Cardiomegaly 7360539 IBIS 81 / 7739
11
 (HPO:0001708) Right ventricular failure 7360539 IBIS 11 / 7739
12
 (HPO:0001650) Aortic valve stenosis 7360539 IBIS 49 / 7739
13
 (HPO:0001649) Tachycardia 7360539 IBIS 53 / 7739
14
 (HPO:0001648) Cor pulmonale 7360539 IBIS 16 / 7739
15
 (HPO:0010702) Increased antibody level in blood Frequent [IBIS] 19040067 IBIS 29 / 7739
16
 (HPO:0004313) Decreased antibody level in blood Occasional [IBIS] 3453998 IBIS 47 / 7739
17
 (HPO:0001945) Fever 7360539 IBIS 218 / 7739
18
 (HPO:0012398) Peripheral edema 7360539 IBIS 12 / 7739
19
 (HPO:0002795) Functional respiratory abnormality 8069020 IBIS 13 / 7739
20
 (HPO:0005952) Decreased pulmonary function 8069020 IBIS 8 / 7739
21
 (HPO:0002206) Pulmonary fibrosis 8069020 IBIS 51 / 7739
22
 (HPO:0002111) Restrictive deficit on pulmonary function testing 16571614 IBIS 25 / 7739
23
 (HPO:0002094) Dyspnea Frequent [IBIS] 19040067 IBIS 132 / 7739
24
 (HPO:0002207) Diffuse reticular or finely nodular infiltrations 19040067 IBIS 11 / 7739
25
 (HPO:0012418) Hypoxemia 8069020 IBIS 18 / 7739
26
 (HPO:0002093) Respiratory insufficiency 16571614 IBIS 410 / 7739
27
 (HPO:0002875) Exertional dyspnea 8069020 IBIS 29 / 7739
28
 (HPO:0006515) Interstitial pneumonitis 19040067 IBIS 13 / 7739
29
 (HPO:0002090) Pneumonia 19040067 IBIS 59 / 7739
30
 (HPO:0006527) Lymphoid interstitial pneumonia Very frequent [IBIS] 19040067 IBIS 1 / 7739
31
 (HPO:0002789) Tachypnea 9361104 IBIS 48 / 7739
32
 (HPO:0002113) Pulmonary infiltrates 19040067 IBIS 36 / 7739
33
 (HPO:0006530) Interstitial pulmonary disease Very frequent [IBIS] 24424167 IBIS 26 / 7739
34
 (HPO:0002103) Abnormality of the pleura 8069020 IBIS 58 / 7739
35
 (HPO:0002729) Follicular hyperplasia 8069020 IBIS 5 / 7739
36
 (HPO:0002716) Lymphadenopathy 8069020 IBIS 129 / 7739
37
 (HPO:0002715) Abnormality of the immune system 9361104 IBIS 46 / 7739
38
 (OMIM) Cough, nonproductive Frequent [IBIS] 19040067 IBIS 5 / 7739
39
 (HPO:0012735) Cough Frequent [IBIS] 19040067 IBIS 24 / 7739
40
 (OMIM) Radiograph shows ground glass appearance 15459629 IBIS 7 / 7739
41
 (HPO:0002878) Respiratory failure 3453998 IBIS 57 / 7739
42
 (MedDRA:10037833) Rales 8069020 IBIS 4 / 7739
43
 (MedDRA:10067182) Bronchial wall thickening 15459629 IBIS 5 / 7739
44
 (OMIM) Honeycomb fibrosis, varying in age and location 8069020 IBIS 6 / 7739
45
 (HPO:0040088) Abnormal lymphocyte count 8069020 IBIS 3 / 7739

Associated genes:

ClinVar (via SNiPA)

Gene symbol Variation Clinical significance Reference

Additional Information: