Recurrent infections

Symptom Information:

Symptom ID: HPO:0002719
Synonyms:
Frequent infections [HPO:0002719]
Frequent, severe infections [HPO:0002719]
Increased frequency of infection [HPO:0002719]
infections, recurrent [HPO:0002719]
Predisposition to infections [HPO:0002719]
Susceptibility to infection [HPO:0002719]
Immune deficiency [Orphanet:47080]
Increased susceptibility to infections (finding) [Orphanet:47080]
Immunodeficiency disorder (disorder) [Orphanet:47080]
Increased susceptibility to infections [Orphanet:47080]
Immunologic Deficiency Syndromes [Orphanet:47080]
Frequent infections [OMIM:Frequent infections]
Frequent, severe infections [OMIM:Frequent, severe infections]
Increased frequency of infection [OMIM:Increased frequency of infection]
Recurrent infections [OMIM:Recurrent infections]
Susceptibility to infection [OMIM:Susceptibility to infection]
Immunodeficiency/increased susceptibility to infections/recurrent infections [Orphanet:47080]
Immunodeficiency [Orphanet:47080]
Infection susceptibility increased [Orphanet:47080]
Immunodeficiency [MedDRA:10061598]
Immunodeficiency NOS [MedDRA:10061598]
Unspecified immunity deficiency [MedDRA:10061598]
Immunocompromised [MedDRA:10061598]
Infection susceptibility increased [MedDRA:10021866]
Increased susceptibility increased [MedDRA:10021866]
Increased susceptibility to infections NOS [MedDRA:10021866]
Infectible easily [MedDRA:10021866]
Infection susceptibility incr [MedDRA:10021866]
Immunodeficiency (e.g. .0001) [OMIM:Immunodeficiency (e.g. .0001)]
No immunodeficiency [OMIM:No immunodeficiency]
Recurrent infections (1 patient) [OMIM:Recurrent infections (1 patient)]
Recurrent infections (fungal, viral, bacterial) [OMIM:Recurrent infections (fungal, viral, bacterial)]
Recurrent infections (in 1 patient) [OMIM:Recurrent infections (in 1 patient)]
Recurrent infections (in severe cases) [OMIM:Recurrent infections (in severe cases)]
Recurrent infections (in some patients) [OMIM:Recurrent infections (in some patients)]
Recurrent infections (increased susceptibility to mycobacterial infection after BCG immunization) [OMIM:Recurrent infections (increased susceptibility to mycobacterial infection after BCG immunization)]
Recurrent infections (pneumonia, sinusitis, fulminant varicella) [OMIM:Recurrent infections (pneumonia, sinusitis, fulminant varicella)]
Recurrent infections (sinusitis and bacterial pneumonia and meningitis) [OMIM:Recurrent infections (sinusitis and bacterial pneumonia and meningitis)]
Quality:
Cross references:
HPO:0002721 "Immunodeficiency" [Orphanet:47080]
HPO:0002718 "Recurrent bacterial infections" [Orphanet:47080]
Orphanet:47080 "Immunodeficiency/increased susceptibility to infections/recurrent infections" [Orphanet:47080]
OMIM: "Frequent infections" [OMIM:Frequent infections]
OMIM: "Frequent, severe infections" [OMIM:Frequent, severe infections]
OMIM: "Increased frequency of infection" [OMIM:Increased frequency of infection]
OMIM: "Recurrent infections" [OMIM:Recurrent infections]
OMIM: "Susceptibility to infection" [OMIM:Susceptibility to infection]
OMIM: "Immunodeficiency (e.g. .0001)" [OMIM:Immunodeficiency (e.g. .0001)]
OMIM: "No immunodeficiency" [OMIM:No immunodeficiency]
OMIM: "Recurrent infections (1 patient)" [OMIM:Recurrent infections (1 patient)]
OMIM: "Recurrent infections (fungal, viral, bacterial)" [OMIM:Recurrent infections (fungal, viral, bacterial)]
OMIM: "Recurrent infections (in 1 patient)" [OMIM:Recurrent infections (in 1 patient)]
OMIM: "Recurrent infections (in severe cases)" [OMIM:Recurrent infections (in severe cases)]
OMIM: "Recurrent infections (in some patients)" [OMIM:Recurrent infections (in some patients)]
OMIM: "Recurrent infections (increased susceptibility to mycobacterial infection after BCG immunization)" [OMIM:Recurrent infections (increased susceptibility to mycobacterial infection after BCG immunization)]
OMIM: "Recurrent infections (pneumonia, sinusitis, fulminant varicella)" [OMIM:Recurrent infections (pneumonia, sinusitis, fulminant varicella)]
OMIM: "Recurrent infections (sinusitis and bacterial pneumonia and meningitis)" [OMIM:Recurrent infections (sinusitis and bacterial pneumonia and meningitis)]
UMLS:C0236171 "Increased susceptibility to infections" [Orphanet:47080]
UMLS:C0021051 "Immunologic Deficiency Syndromes" [Orphanet:47080]
Is a (Direct Parents):
Orphanet Abnormality of the immune system
MedDRA Infections NEC
MedDRA Immunodeficiency disorders NEC
HPO         Abnormality of immune system physiology
Is a (Whole tree): HPO:
All(HPO:0000001)
    Phenotypic abnormality(HPO:0000118)
       Abnormality of the immune system(HPO:0002715)
          Abnormality of immune system physiology(HPO:0010978)
             Recurrent infections(HPO:0002719)
MedDRA:
Infections and infestations(MedDRA:10021881)
    Infections - pathogen unspecified(MedDRA:10021879)
       Infections NEC(MedDRA:10021902)
          Recurrent infections(HPO:0002719)
Immune system disorders(MedDRA:10021428)
    Immunodeficiency syndromes(MedDRA:10021460)
       Immunodeficiency disorders NEC(MedDRA:10052739)
          Recurrent infections(HPO:0002719)
Database Frequency: 107 / 7739
Resource:

All diseases associated with this symptom:

15q24 microdeletion syndrome (Orphanet:94065)
22q11.2 deletion syndrome (Orphanet:567)
3-@METHYLGLUTACONIC ACIDURIA WITH CATARACTS, NEUROLOGIC INVOLVEMENT,AND NEUTROPENIA (OMIM:616271)
AGAMMAGLOBULINEMIA 7, AUTOSOMAL RECESSIVE (OMIM:615214)
ALG13-CDG (Orphanet:324422)
AUTOIMMUNE DISEASE, MULTISYSTEM, INFANTILE-ONSET (OMIM:615952)
AUTOIMMUNE LYMPHOPROLIFERATIVE SYNDROME, TYPE III (OMIM:615559)
Alpha-mannosidosis (Orphanet:61)
Anhidrotic ectodermal dysplasia - immunodeficiency - osteopetrosis - lymphedema (Orphanet:69088)
Arthrogryposis - renal dysfunction - cholestasis (Orphanet:2697)
Aspartylglucosaminuria (Orphanet:93)
Autoinflammation and PLCG2-associated antibody deficiency and immune dysregulation (Orphanet:324530)
Autosomal recessive lymphoproliferative disease (Orphanet:238505)
Autosomal recessive severe congenital neutropenia due to G6PC3 deficiency (Orphanet:331176)
BILIARY MALFORMATION WITH RENAL TUBULAR INSUFFICIENCY (OMIM:210550)
Berardinelli-Seip congenital lipodystrophy (Orphanet:528)
Beta-mannosidosis (Orphanet:118)
Blepharophimosis-intellectual deficit syndrome due to UBE3B deficiency (Orphanet:329255)
Bloom syndrome (Orphanet:125)
C1q DEFICIENCY (OMIM:613652)
CILIARY DISCOORDINATION DUE TO RANDOM CILIARY ORIENTATION (OMIM:215518)
CONGENITAL DISORDER OF GLYCOSYLATION, TYPE IIl (OMIM:614576)
CYSTIC DISEASE OF LUNG (OMIM:219600)
Combined immunodeficiency due to CRAC channel dysfunction (Orphanet:169090)
Combined immunodeficiency due to ORAI1 deficiency (Orphanet:317428)
Common variable immunodeficiency (Orphanet:1572)
Congenital nephrotic syndrome, Finnish type (Orphanet:839)
Cryptosporidiosis - chronic cholangitis - liver disease (Orphanet:357329)
Cushing disease (Orphanet:96253)
Cushing syndrome (Orphanet:553)
Cyclic neutropenia (Orphanet:2686)
DIGEORGE SYNDROME (OMIM:188400)
DYSMYELINATION WITH JAUNDICE (OMIM:224250)
Dubowitz syndrome (Orphanet:235)
ECTODERMAL DYSPLASIA, ANHIDROTIC, WITH T-CELL IMMUNODEFICIENCY, AUTOSOMALDOMINANT (OMIM:612132)
FADD-related immunodeficiency (Orphanet:306550)
FANCONI-LIKE SYNDROME (OMIM:227850)
Familial glucocorticoid deficiency (Orphanet:361)
Fucosidosis (Orphanet:349)
GLUCOCORTICOID DEFICIENCY 1 (OMIM:202200)
GRANULOMATOUS DISEASE, CHRONIC, AUTOSOMAL RECESSIVE, CYTOCHROME b-POSITIVE,TYPE III (OMIM:613960)
Generalized congenital lipodystrophy with myopathy (Orphanet:228429)
Glycogen storage disease due to glucose-6-phosphatase deficiency type b (Orphanet:79259)
HELSMOORTEL-VAN DER AA SYNDROME (OMIM:615873)
HISTIOCYTOSIS, FAMILIAL LIPOCHROME (OMIM:235900)
HOLOPROSENCEPHALY, RECURRENT INFECTIONS, AND MONOCYTOSIS (OMIM:610680)
Hereditary folate malabsorption (Orphanet:90045)
Hypohidrotic ectodermal dysplasia - hypothyroidism - ciliary dyskinesia (Orphanet:1882)
Hypohidrotic ectodermal dysplasia with immunodeficiency (Orphanet:98813)
IMMUNODEFICIENCY 37 (OMIM:616098)
IMMUNODEFICIENCY WITH DEFECTIVE T-CELL RESPONSE TO INTERLEUKIN 1 (OMIM:243110)
IMMUNODEFICIENCY, COMMON VARIABLE, 7 (OMIM:614699)
IMMUNODEFICIENCY, COMMON VARIABLE, 8, WITH AUTOIMMUNITY (OMIM:614700)
IMMUNODEFICIENCY-CENTROMERIC INSTABILITY-FACIAL ANOMALIES SYNDROME2 (OMIM:614069)
Immunodeficiency due to a late component of complements deficiency (Orphanet:169150)
Intellectual deficit, X-linked, Wilson type (Orphanet:85290)
Joubert syndrome 10 (OMIM:300804)
Juvenile hyaline fibromatosis (Orphanet:2028)
LAZY LEUKOCYTE SYNDROME (OMIM:150550)
LEUKOENCEPHALOPATHY, ARTHRITIS, COLITIS, AND HYPOGAMMAGLOBULINEMA (OMIM:608809)
LIPODYSTROPHY, PARTIAL, ACQUIRED, WITH LOW COMPLEMENT COMPONENT C3,WITH OR WITHOUT GLOMERULONEPHRITIS (OMIM:613913)
LYMPHOPROLIFERATIVE SYNDROME 1 (OMIM:613011)
Leprechaunism (Orphanet:508)
Lethal ataxia with deafness and optic atrophy (Orphanet:1187)
Lichstenstein syndrome (Orphanet:2390)
MEGDEL syndrome (Orphanet:352328)
MELAS (Orphanet:550)
MENTAL RETARDATION, AUTOSOMAL DOMINANT 14 (OMIM:614607)
MENTAL RETARDATION, AUTOSOMAL DOMINANT 24 (OMIM:615828)
METAPHYSEAL DYSPLASIA WITHOUT HYPOTRICHOSIS (OMIM:250460)
MONOCYTE AND DENDRITIC CELL DEFICIENCY, AUTOSOMAL RECESSIVE (OMIM:614894)
MYELODYSPLASIA, IMMUNODEFICIENCY, FACIAL DYSMORPHISM, SHORT STATURE,AND PSYCHOMOTOR DELAY (OMIM:601347)
Mitochondrial DNA depletion syndrome, encephalomyopathic form with variable craniofacial anomalies (Orphanet:369897)
Netherton syndrome (Orphanet:634)
Neutropenia, severe congenital, 1, autosomal dominant (OMIM:202700)
ONYCHOTRICHODYSPLASIA AND NEUTROPENIA (OMIM:258360)
PLCG2-associated antibody deficiency and immune dysregulation (Orphanet:300359)
POLYGLUCOSAN BODY MYOPATHY 1 WITH OR WITHOUT IMMUNODEFICIENCY (OMIM:615895)
Partial acquired lipodystrophy (Orphanet:79087)
Pearson syndrome (Orphanet:699)
Persistent polyclonal B-cell lymphocytosis (Orphanet:300324)
Polyarteritis nodosa, childhood-onset (OMIM:615688)
Polyglucosan body myopathy type 1 (ORPHA:397937)
Primary ciliary dyskinesia (Orphanet:244)
Progressive external ophthalmoplegia - myopathy - emaciation (Orphanet:352447)
Prolidase deficiency (Orphanet:742)
Recurrent infection due to specific granule deficiency (Orphanet:169142)
Recurrent infections associated with rare immunoglobulin isotypes deficiency (Orphanet:183675)
Reticular dysgenesis (Orphanet:33355)
Roifman syndrome (Orphanet:353298)
Rubinstein-Taybi syndrome due to 16p13.3 microdeletion (Orphanet:353281)
Rubinstein-Taybi syndrome due to CREBBP mutations (Orphanet:353277)
SHORT STATURE WITH MICROCEPHALY AND DISTINCTIVE FACIES (OMIM:615789)
SLC35A2-CDG (Orphanet:356961)
SPONDYLOENCHONDRODYSPLASIA WITH IMMUNE DYSREGULATION (OMIM:607944)
Say-Barber-Miller syndrome (Orphanet:3132)
Schimke immuno-osseous dysplasia (Orphanet:1830)
Severe combined immunodeficiency due to adenosine deaminase deficiency (Orphanet:277)
Shwachman-Diamond syndrome (Orphanet:811)
T-CELL RECEPTOR-ALPHA/BETA DEFICIENCY (OMIM:615387)
TRICHOTHIODYSTROPHY, PHOTOSENSITIVE (OMIM:601675)
TUFTSIN DEFICIENCY (OMIM:191150)
Timothy syndrome (Orphanet:65283)
VELOCARDIOFACIAL SYNDROME (OMIM:192430)
WISKOTT-ALDRICH SYNDROME 2 (OMIM:614493)
Wolcott-Rallison syndrome (Orphanet:1667)
[DEL] GLYCOGEN STORAGE DISEASE Ib (OMIM:232220)