Spastic paraparesis

Symptom Information:

Symptom ID: HPO:0002313
Synonyms:
Spastic paraparesis [OMIM:Spastic paraparesis]
Spastic paraparesis (1 patient) [OMIM:Spastic paraparesis (1 patient)]
Quality:
Cross references:
OMIM: "Spastic paraparesis" [OMIM:Spastic paraparesis]
OMIM: "Spastic paraparesis (1 patient)" [OMIM:Spastic paraparesis (1 patient)]
Is a (Direct Parents):
HPO         Paraparesis
HPO         Lower limb spasticity
Is a (Whole tree): HPO:
All(HPO:0000001)
    Phenotypic abnormality(HPO:0000118)
       Abnormality of the nervous system(HPO:0000707)
          Abnormality of nervous system physiology(HPO:0012638)
             Abnormality of central motor function(HPO:0011442)
                Abnormal pyramidal signs(HPO:0007256)
                   Hypertonia(HPO:0001276)
                      Spasticity(HPO:0001257)
                         Lower limb spasticity(HPO:0002061)
                            Spastic paraparesis(HPO:0002313)
                   Weakness due to upper motor neuron dysfunction(HPO:0010549)
                      Paraplegia/paraparesis(HPO:0010551)
                         Paraparesis(HPO:0002385)
                            Spastic paraparesis(HPO:0002313)
MedDRA:
Database Frequency: 33 / 7739
Resource:

All diseases associated with this symptom:

3-methylglutaconic aciduria type 3 (Orphanet:67047)
Arachnoiditis (Orphanet:137817)
Autosomal dominant spastic paraplegia type 31 (Orphanet:101011)
Autosomal dominant spastic paraplegia type 4 (Orphanet:100985)
Autosomal recessive spastic ataxia - optic atrophy - dysarthria (Orphanet:254343)
Autosomal recessive spastic paraplegia type 20 (Orphanet:101000)
Autosomal recessive spastic paraplegia type 21 (Orphanet:101001)
Autosomal recessive spastic paraplegia type 35 (Orphanet:171629)
Autosomal recessive spastic paraplegia type 48 (Orphanet:306511)
Autosomal recessive spastic paraplegia type 7 (Orphanet:99013)
BRANCHIAL MYOCLONUS WITH SPASTIC PARAPARESIS AND CEREBELLAR ATAXIA (OMIM:113610)
Behr syndrome (Orphanet:1239)
Beta-propeller protein-associated neurodegeneration (Orphanet:329284)
Cirrhosis-dystonia-polycythemia-hypermanganesemia syndrome (Orphanet:309854)
Classical phenylketonuria (Orphanet:79254)
Early-onset spastic ataxia-neuropathy syndrome (Orphanet:313772)
Gaucher disease type 3 (Orphanet:77261)
Hyperornithinemia-hyperammonemia-homocitrullinuria (Orphanet:415)
Leber plus disease (Orphanet:99718)
MITOCHONDRIAL COMPLEX III DEFICIENCY, NUCLEAR TYPE 2 (OMIM:615157)
NEURODEGENERATION WITH BRAIN IRON ACCUMULATION 6 (OMIM:615643)
Neurologic Waardenburg-Shah syndrome (Orphanet:163746)
Oculofaciocardiodental syndrome (Orphanet:2712)
Pelizaeus-Merzbacher-like disease (Orphanet:280270)
Pelizaeus-Merzbacher-like due to AIMP1 mutation (Orphanet:280293)
Pelizaeus-Merzbacher-like due to GJC2 mutation (Orphanet:280282)
Pyruvate dehydrogenase E3-binding protein deficiency (Orphanet:255182)
SPINOCEREBELLAR ATAXIA 40 (OMIM:616053)
Spastic paraparesis - deafness (Orphanet:2815)
Spastic paraplegia - epilepsy - intellectual deficit (Orphanet:2816)
Spastic paraplegia type 2 (Orphanet:99015)
Tropical spastic paraparesis (Orphanet:289326)
Waardenburg-Shah syndrome (Orphanet:897)