Tropical spastic paraparesis
General Information (adopted from Orphanet):
| Synonyms, Signs: |
FAMILIAL SPASTIC PARAPARESIS, HTLV-1-ASSOCIATED HAM/TSP TSP HAM Human T-lymphotropic virus type-1-associated myelopathy/tropical spastic paraparesis HTLV-1-associated myelopathy/tropical spastic paraparesis Human T-lymphotropic virus type I-associated myelopathy/tropical spastic paraparesis |
| Number of Symptoms | 5 |
| OrphanetNr: | 289326 |
| OMIM Id: |
159580
|
| ICD-10: |
G04.1 |
| UMLs: |
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| MeSH: |
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| MedDRA: |
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| Snomed: |
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Prevalence, inheritance and age of onset:
| Prevalence: | No data available. |
| Inheritance: |
Not applicable [Orphanet] |
| Age of onset: |
Adult [Orphanet] |
Disease classification (adopted from Orphanet):
| Parent Diseases: |
Infectious disease of the nervous system
-Rare neurologic disease Rare viral disease -Rare infectious disease |
Symptom Information:
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(HPO:0007256) | Abnormal pyramidal signs | 116 / 7739 | ||||
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(HPO:0002313) | Spastic paraparesis | 33 / 7739 | ||||
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(OMIM) | Mild or no sensory disturbance | 1 / 7739 | ||||
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(OMIM) | Anti-HTLV-I antibodies in both serum and CSF | 1 / 7739 | ||||
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(HPO:0002196) | Myelopathy | 6 / 7739 |
Associated genes:
ClinVar (via SNiPA)
| Gene symbol | Variation | Clinical significance | Reference |
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