|
1
|
(HPO:0001258)
|
Spastic paraplegia |
Very frequent [IBIS]
|
|
21659953
|
IBIS
|
97 / 7739
|
|
2
|
(HPO:0007340)
|
Lower limb muscle weakness |
Very frequent [IBIS]
|
|
21659953
|
IBIS
|
61 / 7739
|
|
3
|
(HPO:0010550)
|
Paraplegia |
Very frequent [IBIS]
|
|
17895902
|
IBIS
|
10 / 7739
|
|
4
|
(HPO:0002191)
|
Progressive spasticity |
Very frequent [IBIS]
|
|
21659953
|
IBIS
|
12 / 7739
|
|
5
|
(HPO:0000716)
|
Depression |
Frequent [IBIS]
|
|
26806216
|
IBIS
|
99 / 7739
|
|
6
|
(HPO:0012531)
|
Pain |
Frequent [IBIS]
|
|
26806216
|
IBIS
|
9 / 7739
|
|
7
|
(HPO:0012378)
|
Fatigue |
Frequent [IBIS]
|
|
26806216
|
IBIS
|
50 / 7739
|
|
8
|
(HPO:0000012)
|
Urinary urgency |
|
|
9507385
|
IBIS
|
35 / 7739
|
|
9
|
(HPO:0000020)
|
Urinary incontinence |
|
|
9507385
|
IBIS
|
75 / 7739
|
|
10
|
(HPO:0000726)
|
Dementia |
|
|
21659953
|
IBIS
|
131 / 7739
|
|
11
|
(HPO:0001249)
|
Intellectual disability |
|
|
15939438
|
IBIS
|
1089 / 7739
|
|
12
|
(HPO:0001347)
|
Hyperreflexia |
|
|
12124993
|
IBIS
|
363 / 7739
|
|
13
|
(HPO:0002064)
|
Spastic gait |
|
|
26094131
|
IBIS
|
46 / 7739
|
|
14
|
(HPO:0002166)
|
Impaired vibration sensation in the lower limbs |
|
|
17895902
|
IBIS
|
26 / 7739
|
|
15
|
(HPO:0002314)
|
Degeneration of the lateral corticospinal tracts |
|
|
25658484
|
IBIS
|
9 / 7739
|
|
16
|
(HPO:0002354)
|
Memory impairment |
|
|
15939438
|
IBIS
|
63 / 7739
|
|
17
|
(HPO:0002839)
|
Urinary bladder sphincter dysfunction |
|
|
12124993
|
IBIS
|
34 / 7739
|
|
18
|
(HPO:0003487)
|
Babinski sign |
|
|
12124993
|
IBIS
|
179 / 7739
|
|
19
|
(HPO:0002061)
|
Lower limb spasticity |
|
|
21659953
|
IBIS
|
56 / 7739
|
|
20
|
(HPO:0007256)
|
Abnormal pyramidal signs |
|
|
17895902
|
IBIS
|
116 / 7739
|
|
21
|
(HPO:0001268)
|
Mental deterioration |
|
|
21659953
|
IBIS
|
88 / 7739
|
|
22
|
(HPO:0003676)
|
Progressive disorder |
|
|
9507385
|
IBIS
|
148 / 7739
|
|
23
|
(HPO:0001288)
|
Gait disturbance |
|
|
12124993
|
IBIS
|
318 / 7739
|
|
24
|
(HPO:0002313)
|
Spastic paraparesis |
|
|
12124993
|
IBIS
|
33 / 7739
|
|
25
|
(HPO:0002395)
|
Lower limb hyperreflexia |
|
|
12124993
|
IBIS
|
26 / 7739
|
|
26
|
(HPO:0011448)
|
Ankle clonus |
|
|
12124993
|
IBIS
|
31 / 7739
|
|
27
|
(HPO:0001260)
|
Dysarthria |
|
|
12124993
|
IBIS
|
329 / 7739
|
|
28
|
(HPO:0002015)
|
Dysphagia |
|
|
12124993
|
IBIS
|
301 / 7739
|
|
29
|
(HPO:0007199)
|
Progressive spastic paraparesis |
|
|
12124993
|
IBIS
|
3 / 7739
|
|
30
|
(HPO:0100543)
|
Cognitive impairment |
|
|
17594340
|
IBIS
|
230 / 7739
|
|
31
|
(HPO:0001272)
|
Cerebellar atrophy |
|
|
17594340
|
IBIS
|
197 / 7739
|
|
32
|
(HPO:0001250)
|
Seizures |
|
|
17594340
|
IBIS
|
1245 / 7739
|
|
33
|
(HPO:0003401)
|
Paresthesia |
|
|
26806216
|
IBIS
|
42 / 7739
|
|
34
|
(HPO:0001271)
|
Polyneuropathy |
|
|
26806216
|
IBIS
|
56 / 7739
|
|
35
|
(HPO:0009830)
|
Peripheral neuropathy |
|
|
25758904
|
IBIS
|
206 / 7739
|
|
36
|
(HPO:0002133)
|
Status epilepticus |
|
|
9507385
|
IBIS
|
59 / 7739
|
|
37
|
(HPO:0000365)
|
Hearing impairment |
|
|
9507385
|
IBIS
|
539 / 7739
|
|
38
|
(HPO:0001348)
|
Brisk reflexes |
|
|
9507385
|
IBIS
|
15 / 7739
|
|
39
|
(HPO:0001761)
|
Pes cavus |
|
|
9507385
|
IBIS
|
225 / 7739
|
|
40
|
(HPO:0001273)
|
Abnormality of the corpus callosum |
|
|
25658484
|
IBIS
|
20 / 7739
|
|
41
|
(HPO:0002062)
|
Morphological abnormality of the pyramidal tract |
|
|
25658484
|
IBIS
|
24 / 7739
|
|
42
|
(HPO:0000709)
|
Psychosis |
|
|
24954637
|
IBIS
|
61 / 7739
|
|
43
|
(HPO:0006986)
|
Upper limb spasticity |
|
|
24954637
|
IBIS
|
15 / 7739
|
|
44
|
(HPO:0000932)
|
Abnormality of the posterior cranial fossa |
|
|
24954637
|
IBIS
|
5 / 7739
|
|
45
|
(HPO:0002378)
|
Hand tremor |
|
|
24954637
|
IBIS
|
9 / 7739
|
|
46
|
(HPO:0002500)
|
Abnormality of the cerebral white matter |
|
|
24954637
|
IBIS
|
73 / 7739
|
|
47
|
(HPO:0006006)
|
Hypotrophy of the small hand muscles |
|
|
24954637
|
IBIS
|
4 / 7739
|