Immunodeficiency

Symptom Information:

Symptom ID: HPO:0002721
Synonyms:
Immune deficiency [HPO:0002721]
Immune deficiency [Orphanet:47080]
Increased susceptibility to infections (finding) [Orphanet:47080]
Immunodeficiency disorder (disorder) [Orphanet:47080]
Increased susceptibility to infections [Orphanet:47080]
Immunologic Deficiency Syndromes [Orphanet:47080]
Immune deficiency [OMIM:Immune deficiency]
Immunodeficiency [OMIM:Immunodeficiency]
Immunodeficiency/increased susceptibility to infections/recurrent infections [Orphanet:47080]
Immunodeficiency [Orphanet:47080]
Infection susceptibility increased [Orphanet:47080]
Immunodeficiency [MedDRA:10061598]
Immunodeficiency NOS [MedDRA:10061598]
Unspecified immunity deficiency [MedDRA:10061598]
Immunocompromised [MedDRA:10061598]
Infection susceptibility increased [MedDRA:10021866]
Increased susceptibility increased [MedDRA:10021866]
Increased susceptibility to infections NOS [MedDRA:10021866]
Infectible easily [MedDRA:10021866]
Infection susceptibility incr [MedDRA:10021866]
Immunodeficiency (e.g. .0001) [OMIM:Immunodeficiency (e.g. .0001)]
No immunodeficiency [OMIM:No immunodeficiency]
Quality:
Cross references:
HPO:0002718 "Recurrent bacterial infections" [Orphanet:47080]
HPO:0002719 "Recurrent infections" [Orphanet:47080]
Orphanet:47080 "Immunodeficiency/increased susceptibility to infections/recurrent infections" [Orphanet:47080]
OMIM: "Immune deficiency" [OMIM:Immune deficiency]
OMIM: "Immunodeficiency" [OMIM:Immunodeficiency]
OMIM: "Immunodeficiency (e.g. .0001)" [OMIM:Immunodeficiency (e.g. .0001)]
OMIM: "No immunodeficiency" [OMIM:No immunodeficiency]
UMLS:C0021051 "Immunodeficiency" [HPO:0002721]
UMLS:C0236171 "Increased susceptibility to infections" [Orphanet:47080]
UMLS:C0021051 "Immunologic Deficiency Syndromes" [Orphanet:47080]
Is a (Direct Parents):
MedDRA Immunodeficiency disorders NEC
HPO         Abnormality of immune system physiology
Orphanet Abnormality of the immune system
MedDRA Infections NEC
Is a (Whole tree): HPO:
All(HPO:0000001)
    Phenotypic abnormality(HPO:0000118)
       Abnormality of the immune system(HPO:0002715)
          Abnormality of immune system physiology(HPO:0010978)
             Immunodeficiency(HPO:0002721)
MedDRA:
Immune system disorders(MedDRA:10021428)
    Immunodeficiency syndromes(MedDRA:10021460)
       Immunodeficiency disorders NEC(MedDRA:10052739)
          Immunodeficiency(HPO:0002721)
Infections and infestations(MedDRA:10021881)
    Infections - pathogen unspecified(MedDRA:10021879)
       Infections NEC(MedDRA:10021902)
          Immunodeficiency(HPO:0002721)
Database Frequency: 97 / 7739
Resource:

All diseases associated with this symptom:

Anhidrotic ectodermal dysplasia - immunodeficiency - osteopetrosis - lymphedema (Orphanet:69088)
Autosomal recessive hyper-IgE syndrome due to TYK2 deficiency (Orphanet:331226)
Autosomal recessive severe congenital neutropenia due to G6PC3 deficiency (Orphanet:331176)
Berardinelli-Seip congenital lipodystrophy (Orphanet:528)
Bloom syndrome (Orphanet:125)
CANDIDIASIS, FAMILIAL, 2 (OMIM:212050)
CD3 ANTIGEN, EPSILON SUBUNIT (OMIM:186830)
CD3 ANTIGEN, GAMMA SUBUNIT (OMIM:186740)
CHONDROITIN-6-SULFATURIA, DEFECTIVE CELLULAR IMMUNITY, NEPHROTIC SYNDROME (OMIM:215250)
Combined immunodeficiency due to CRAC channel dysfunction (Orphanet:169090)
Combined immunodeficiency due to STIM1 deficiency (Orphanet:317430)
Combined immunodeficiency due to STK4 deficiency (Orphanet:314689)
Common variable immunodeficiency (Orphanet:1572)
Cryptosporidiosis - chronic cholangitis - liver disease (Orphanet:357329)
Cushing disease (Orphanet:96253)
Cushing syndrome (Orphanet:553)
Facial dysmorphism - immunodeficiency - livedo - short stature (Orphanet:352712)
Glycogen storage disease due to glucose-6-phosphatase deficiency type b (Orphanet:79259)
HYPERZINCEMIA WITH FUNCTIONAL ZINC DEPLETION (OMIM:601979)
Hepatic veno-occlusive disease - immunodeficiency (Orphanet:79124)
Hermansky-Pudlak syndrome (Orphanet:79430)
Hermansky-Pudlak syndrome with neutropenia (Orphanet:183678)
Hoyeraal-Hreidarsson syndrome (Orphanet:3322)
Hyper-IgM syndrome type 2 (Orphanet:101089)
Hyper-IgM syndrome type 3 (Orphanet:101090)
Hyper-IgM syndrome type 4 (Orphanet:101091)
Hyper-IgM syndrome type 5 (Orphanet:101092)
Hypohidrotic ectodermal dysplasia with immunodeficiency (Orphanet:98813)
ICF syndrome (Orphanet:2268)
IMMUNODEFICIENCY 12 (OMIM:615468)
IMMUNODEFICIENCY 14 (OMIM:615513)
IMMUNODEFICIENCY 15 (OMIM:615592)
IMMUNODEFICIENCY 16 (OMIM:615593)
IMMUNODEFICIENCY 17 (OMIM:615607)
IMMUNODEFICIENCY 18 (OMIM:615615)
IMMUNODEFICIENCY 19 (OMIM:615617)
IMMUNODEFICIENCY 20 (OMIM:615707)
IMMUNODEFICIENCY 22 (OMIM:615758)
IMMUNODEFICIENCY 23 (OMIM:615816)
IMMUNODEFICIENCY 25 (OMIM:610163)
IMMUNODEFICIENCY 28 (OMIM:614889)
IMMUNODEFICIENCY 29 (OMIM:614890)
IMMUNODEFICIENCY 30 (OMIM:614891)
IMMUNODEFICIENCY 31A (OMIM:614892)
IMMUNODEFICIENCY 31C (OMIM:614162)
IMMUNODEFICIENCY 36 (OMIM:616005)
IMMUNODEFICIENCY 37 (OMIM:616098)
IMMUNODEFICIENCY 38, WITH BASAL GANGLIA CALCIFICATION (OMIM:616126)
IMMUNODEFICIENCY WITH DEFECTIVE LEUKOCYTE AND LYMPHOCYTE FUNCTIONAND WITH RESPONSE TO HISTAMINE-1 ANTAGONIST (OMIM:146840)
IMMUNODEFICIENCY WITHOUT ANHIDROTIC ECTODERMAL DYSPLASIA (OMIM:300584)
IMMUNODEFICIENCY, COMMON VARIABLE, 1 (OMIM:607594)
IMMUNODEFICIENCY, COMMON VARIABLE, 10 (OMIM:615577)
IMMUNODEFICIENCY, COMMON VARIABLE, 11 (OMIM:615767)
IMMUNODEFICIENCY, COMMON VARIABLE, 2 (OMIM:240500)
IMMUNODEFICIENCY, COMMON VARIABLE, 3 (OMIM:613493)
IMMUNODEFICIENCY, COMMON VARIABLE, 4 (OMIM:613494)
IMMUNODEFICIENCY, COMMON VARIABLE, 5 (OMIM:613495)
IMMUNODEFICIENCY, COMMON VARIABLE, 6 (OMIM:613496)
IMMUNODEFICIENCY, COMMON VARIABLE, 7 (OMIM:614699)
IMMUNODEFICIENCY, COMMON VARIABLE, 8, WITH AUTOIMMUNITY (OMIM:614700)
IMMUNODEFICIENCY, PARTIAL COMBINED, WITH ABSENCE OF HLA DETERMINANTSAND BETA-2-MICROGLOBULIN FROM LYMPHOCYTES (OMIM:242870)
IMMUNODEFICIENCY, X-LINKED, WITH DEFICIENCY OF 115,000 DALTON SURFACEGLYCOPROTEIN (OMIM:308220)
IMMUNODEFICIENCY-CENTROMERIC INSTABILITY-FACIAL ANOMALIES SYNDROME2 (OMIM:614069)
Idiopathic CD4 lymphocytopenia (Orphanet:228000)
Immunodeficiency due to CD25 deficiency (Orphanet:169100)
Immunodeficiency due to ficolin3 deficiency (Orphanet:331190)
Immunodeficiency due to interleukin-1 receptor-associated kinase-4 deficiency (Orphanet:70592)
Intellectual deficit, X-linked, Wilson type (Orphanet:85290)
LYMPHOPROLIFERATIVE SYNDROME, X-LINKED, 1 (OMIM:308240)
Leigh syndrome (Orphanet:506)
Leprechaunism (Orphanet:508)
Lethal ataxia with deafness and optic atrophy (Orphanet:1187)
Lung fibrosis - immunodeficiency - 46,XX gonadal dysgenesis (Orphanet:137631)
MEGDEL syndrome (Orphanet:352328)
MELAS (Orphanet:550)
METAPHYSEAL DYSPLASIA WITHOUT HYPOTRICHOSIS (OMIM:250460)
Monocytopenia with susceptibility to infections (Orphanet:228423)
NEUTROPHIL MIGRATION (OMIM:162820)
Neutrophil immunodeficiency syndrome (Orphanet:183707)
POLYGLUCOSAN BODY MYOPATHY 1 WITH OR WITHOUT IMMUNODEFICIENCY (OMIM:615895)
Partial acquired lipodystrophy (Orphanet:79087)
Polyarteritis nodosa, childhood-onset (OMIM:615688)
Polyglucosan body myopathy type 1 (ORPHA:397937)
Progeria - short stature - pigmented nevi (Orphanet:2959)
RIDDLE SYNDROME (OMIM:611943)
Reticular dysgenesis (Orphanet:33355)
Severe combined immunodeficiency due to CARD11 deficiency (Orphanet:357237)
Severe combined immunodeficiency due to CORO1A deficiency (Orphanet:228003)
Severe combined immunodeficiency due to adenosine deaminase deficiency (Orphanet:277)
TRICHOHEPATOENTERIC SYNDROME 2 (OMIM:614602)
Timothy syndrome (Orphanet:65283)
Wolcott-Rallison syndrome (Orphanet:1667)
Wolf-Hirschhorn syndrome (Orphanet:280)
X-linked hyper-IgM syndrome (Orphanet:101088)
X-linked immunodeficiency with magnesium defect, Epstein-Barr virus infection and neoplasia (Orphanet:317476)
X-linked mendelian susceptibility to mycobacterial diseases (Orphanet:319605)
[DEL] GLYCOGEN STORAGE DISEASE Ib (OMIM:232220)