Generalized tonic-clonic seizures

Symptom Information:

Symptom ID: HPO:0002069
Synonyms:
Generalised tonic-clonic seizures [HPO:0002069]
Generalized clonic-tonic seizures [HPO:0002069]
Generalized tonic clonic seizures [HPO:0002069]
Grand mal seizures [HPO:0002069]
Seizures, generalized tonic-clonic [HPO:0002069]
Seizures, generalized, tonic-clonic [HPO:0002069]
Seizures, tonic-clonic [HPO:0002069]
Generalized clonic-tonic seizures [OMIM:Generalized clonic-tonic seizures]
Generalized tonic clonic seizures [OMIM:Generalized tonic clonic seizures]
Generalized tonic-clonic seizures [OMIM:Generalized tonic-clonic seizures]
Grand mal seizures [OMIM:Grand mal seizures]
Seizures, generalized tonic-clonic [OMIM:Seizures, generalized tonic-clonic]
Seizures, tonic-clonic [OMIM:Seizures, tonic-clonic]
Generalized tonic-clonic seizure [OMIM:Generalized tonic-clonic seizure]
Generalized tonic-clonic seizures (GTCS) [OMIM:Generalized tonic-clonic seizures (GTCS)]
Generalized tonic-clonic seizures (GTCS) (in most patients) [OMIM:Generalized tonic-clonic seizures (GTCS) (in most patients)]
Generalized tonic-clonic seizures (often develop in adolescence) [OMIM:Generalized tonic-clonic seizures (often develop in adolescence)]
Generalized tonic-clonic seizures (rare) [OMIM:Generalized tonic-clonic seizures (rare)]
Generalized tonic-clonic seizures (stage 2 and 3) [OMIM:Generalized tonic-clonic seizures (stage 2 and 3)]
Seizures, clonic-tonic [OMIM:Seizures, clonic-tonic]
Seizures, generalized tonic-clonic (GTCS) [OMIM:Seizures, generalized tonic-clonic (GTCS)]
Seizures, tonic-clonic (1 patient) [OMIM:Seizures, tonic-clonic (1 patient)]
Tonic-clonic seizures [OMIM:Tonic-clonic seizures]
Tonic-clonic seizures (less common) [OMIM:Tonic-clonic seizures (less common)]
Generalised tonic-clonic seizures [MedDRA:10018101]
Quality:
Cross references:
OMIM: "Generalized clonic-tonic seizures" [OMIM:Generalized clonic-tonic seizures]
OMIM: "Generalized tonic clonic seizures" [OMIM:Generalized tonic clonic seizures]
OMIM: "Generalized tonic-clonic seizures" [OMIM:Generalized tonic-clonic seizures]
OMIM: "Grand mal seizures" [OMIM:Grand mal seizures]
OMIM: "Seizures, generalized tonic-clonic" [OMIM:Seizures, generalized tonic-clonic]
OMIM: "Seizures, tonic-clonic" [OMIM:Seizures, tonic-clonic]
OMIM: "Generalized tonic-clonic seizure" [OMIM:Generalized tonic-clonic seizure]
OMIM: "Generalized tonic-clonic seizures (GTCS)" [OMIM:Generalized tonic-clonic seizures (GTCS)]
OMIM: "Generalized tonic-clonic seizures (GTCS) (in most patients)" [OMIM:Generalized tonic-clonic seizures (GTCS) (in most patients)]
OMIM: "Generalized tonic-clonic seizures (often develop in adolescence)" [OMIM:Generalized tonic-clonic seizures (often develop in adolescence)]
OMIM: "Generalized tonic-clonic seizures (rare)" [OMIM:Generalized tonic-clonic seizures (rare)]
OMIM: "Generalized tonic-clonic seizures (stage 2 and 3)" [OMIM:Generalized tonic-clonic seizures (stage 2 and 3)]
OMIM: "Seizures, clonic-tonic" [OMIM:Seizures, clonic-tonic]
OMIM: "Seizures, generalized tonic-clonic (GTCS)" [OMIM:Seizures, generalized tonic-clonic (GTCS)]
OMIM: "Seizures, tonic-clonic (1 patient)" [OMIM:Seizures, tonic-clonic (1 patient)]
OMIM: "Tonic-clonic seizures" [OMIM:Tonic-clonic seizures]
OMIM: "Tonic-clonic seizures (less common)" [OMIM:Tonic-clonic seizures (less common)]
Is a (Direct Parents):
HPO         Generalized seizures
MedDRA Seizures
Is a (Whole tree): HPO:
All(HPO:0000001)
    Phenotypic abnormality(HPO:0000118)
       Abnormality of the nervous system(HPO:0000707)
          Abnormality of nervous system physiology(HPO:0012638)
             Seizures(HPO:0001250)
                Generalized seizures(HPO:0002197)
                   Generalized tonic-clonic seizures(HPO:0002069)
MedDRA:
Nervous system disorders(MedDRA:10029205)
    Seizures(HPO:0001250)
       Generalized tonic-clonic seizures(HPO:0002069)
Database Frequency: 96 / 7739
Resource:

All diseases associated with this symptom:

4-hydroxybutyric aciduria (Orphanet:22)
Aldosterone-producing adenoma with seizures and neurological abnormalities (Orphanet:369929)
Alopecia - intellectual deficit - hypergonadotropic hypogonadism (Orphanet:1014)
Alström syndrome (Orphanet:64)
Alternating hemiplegia of childhood (Orphanet:2131)
Amish infantile epilepsy syndrome (Orphanet:171714)
Arterial calcification, generalized, of infancy, 1 (OMIM:208000)
Benign adult familial myoclonic epilepsy (Orphanet:86814)
Benign familial neonatal seizures (Orphanet:1949)
Beta-mannosidosis (Orphanet:118)
Bilateral polymicrogyria (Orphanet:268940)
Childhood absence epilepsy (Orphanet:64280)
Christianson syndrome (Orphanet:85278)
Combined oxidative phosphorylation defect type 15 (Orphanet:319524)
Dyschromatosis universalis hereditaria 1 (OMIM:127500)
Dyschromatosis universalis hereditaria 2 (OMIM:612715)
Dyschromatosis universalis hereditaris 3 (OMIM:615402)
EPILEPSY, CHILDHOOD ABSENCE, SUSCEPTIBILITY TO, 1 (OMIM:600131)
EPILEPSY, CHILDHOOD ABSENCE, SUSCEPTIBILITY TO, 2 (OMIM:607681)
EPILEPSY, FAMILIAL ADULT MYOCLONIC, 2 (OMIM:607876)
EPILEPSY, FAMILIAL ADULT MYOCLONIC, 3 (OMIM:613608)
EPILEPSY, FAMILIAL ADULT MYOCLONIC, 4 (OMIM:615127)
EPILEPSY, FAMILIAL ADULT MYOCLONIC, 5 (OMIM:615400)
EPILEPSY, FAMILIAL TEMPORAL LOBE, 2 (OMIM:608096)
EPILEPSY, IDIOPATHIC GENERALIZED (OMIM:600669)
EPILEPSY, IDIOPATHIC GENERALIZED, SUSCEPTIBILITY TO, 10 (OMIM:613060)
EPILEPSY, IDIOPATHIC GENERALIZED, SUSCEPTIBILITY TO, 12 (OMIM:614847)
EPILEPSY, IDIOPATHIC GENERALIZED, SUSCEPTIBILITY TO, 3 (OMIM:608762)
EPILEPSY, IDIOPATHIC GENERALIZED, SUSCEPTIBILITY TO, 7 (OMIM:604827)
EPILEPSY, JUVENILE MYOCLONIC, SUSCEPTIBILITY TO, 9 (OMIM:614280)
EPILEPSY, MYOCLONIC JUVENILE (OMIM:254770)
EPILEPSY, NOCTURNAL FRONTAL LOBE, 2 (OMIM:603204)
EPILEPSY, PROGRESSIVE MYOCLONIC, 1B (OMIM:612437)
EPILEPSY, PROGRESSIVE MYOCLONIC, 8 (OMIM:616230)
EPILEPTIC ENCEPHALOPATHY, CHILDHOOD-ONSET (OMIM:615369)
EPILEPTIC ENCEPHALOPATHY, EARLY INFANTILE, 11 (OMIM:613721)
EPILEPTIC ENCEPHALOPATHY, EARLY INFANTILE, 2 (OMIM:300672)
EPILEPTIC ENCEPHALOPATHY, EARLY INFANTILE, 30 (OMIM:616341)
EPILEPTIC ENCEPHALOPATHY, EARLY INFANTILE, 4 (OMIM:612164)
Early-onset spastic ataxia-neuropathy syndrome (Orphanet:313772)
Encephalopathy due to beta-mercaptolactate-cysteine disulfiduria (Orphanet:1035)
FEBRILE SEIZURES, FAMILIAL, 1 (OMIM:121210)
FEBRILE SEIZURES, FAMILIAL, 11 (OMIM:614418)
FEBRILE SEIZURES, FAMILIAL, 2 (OMIM:602477)
FEBRILE SEIZURES, FAMILIAL, 4 (OMIM:604352)
FEBRILE SEIZURES, FAMILIAL, 5 (OMIM:609255)
FEBRILE SEIZURES, FAMILIAL, 6 (OMIM:609253)
Familial infantile myoclonic epilepsy (Orphanet:352582)
Familial temporal epilepsy (Orphanet:98819)
Female restricted epilepsy with intellectual deficit (Orphanet:101039)
GENERALIZED EPILEPSY WITH FEBRILE SEIZURES PLUS, TYPE 1 (OMIM:604233)
GENERALIZED EPILEPSY WITH FEBRILE SEIZURES PLUS, TYPE 2 (OMIM:604403)
GENERALIZED EPILEPSY WITH FEBRILE SEIZURES PLUS, TYPE 3 (OMIM:611277)
GENERALIZED EPILEPSY WITH FEBRILE SEIZURES PLUS, TYPE 4 (OMIM:609800)
GENERALIZED EPILEPSY WITH FEBRILE SEIZURES PLUS, TYPE 7 (OMIM:613863)
GENERALIZED EPILEPSY WITH FEBRILE SEIZURES PLUS, TYPE 9 (OMIM:616172)
GROWTH FAILURE, MICROCEPHALY, MENTAL RETARDATION, CATARACTS, LARGEJOINT CONTRACTURES, OSTEOPOROSIS, CORTICAL DYSPLASIA, AND CEREBELLARATROPHY (OMIM:608278)
Gaucher disease - ophthalmoplegia - cardiovascular calcification (Orphanet:2072)
Gaucher disease type 3 (Orphanet:77261)
Generalized epilepsy - paroxysmal dyskinesia (Orphanet:79137)
Generalized epilepsy with febrile seizures-plus context (Orphanet:36387)
Glycogen storage disease due to muscle and heart glycogen synthase deficiency (Orphanet:137625)
Hallermann-Streiff syndrome (Orphanet:2108)
Hyperinsulinism-hyperammonemia syndrome (Orphanet:35878)
Hypouricemia, renal, 1 (OMIM:220150)
Juvenile absence epilepsy (Orphanet:1941)
Juvenile myoclonic epilepsy (Orphanet:307)
LEUKOENCEPHALOPATHY, ARTHRITIS, COLITIS, AND HYPOGAMMAGLOBULINEMA (OMIM:608809)
Lafora disease (Orphanet:501)
MELAS (Orphanet:550)
MENTAL RETARDATION, AUTOSOMAL RECESSIVE 49 (OMIM:616281)
MERRF (Orphanet:551)
MOLYBDENUM COFACTOR DEFICIENCY, COMPLEMENTATION GROUP C (OMIM:615501)
MOSAIC VARIEGATED ANEUPLOIDY SYNDROME 1 (OMIM:257300)
MYOCLONIC EPILEPSY OF UNVERRICHT AND LUNDBORG (OMIM:254800)
MYOCLONIC EPILEPSY, JUVENILE, SUSCEPTIBILITY TO, 4 (OMIM:611364)
Mosaic variegated aneuploidy syndrome (Orphanet:1052)
Mucopolysaccharidosis type 2 (Orphanet:580)
Necrotizing encephalomyelopathy, subacute, of Leigh, adult (OMIM:161700)
Occipital pachygyria and polymicrogyria (Orphanet:280640)
PELGER-HUET ANOMALY (OMIM:169400)
Pachygyria - intellectual deficit - epilepsy (Orphanet:2798)
Paroxysmal dystonic choreathetosis with episodic ataxia and spasticity (Orphanet:53583)
Perrault Syndrome 5 (OMIM:616138)
Pontocerebellar hypoplasia, type 9 (OMIM:615809)
Progressive epilepsy-intellectual deficit, Finnish type (Orphanet:1947)
Progressive myoclonic epilepsy type 6 (Orphanet:280620)
Pyridoxine-dependent epilepsy (Orphanet:3006)
SEIZURES, BENIGN FAMILIAL NEONATAL, 1 (OMIM:121200)
SEIZURES, BENIGN FAMILIAL NEONATAL, 2 (OMIM:121201)
SEIZURES, BENIGN FAMILIAL NEONATAL, 3 (OMIM:608217)
SEIZURES, BENIGN FAMILIAL NEONATAL, AUTOSOMAL RECESSIVE (OMIM:269720)
Sneddon syndrome (Orphanet:820)
Unverricht-Lundborg disease (Orphanet:308)
X-linked intellectual disability, Hedera type (Orphanet:93952)
Zellweger-like syndrome without peroxisomal anomalies (Orphanet:50812)