Generalized epilepsy with febrile seizures-plus context
General Information (adopted from Orphanet):
| Synonyms, Signs: |
GEFS+ |
| Number of Symptoms | 6 |
| OrphanetNr: | 36387 |
| OMIM Id: |
604233
604403 609800 611277 612279 613060 613828 613863 |
| ICD-10: |
G40.3 |
| UMLs: |
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| MeSH: |
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| MedDRA: |
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| Snomed: |
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Prevalence, inheritance and age of onset:
| Prevalence: | No data available. |
| Inheritance: |
Autosomal dominant [Orphanet] |
| Age of onset: |
Childhood [Orphanet] |
Disease classification (adopted from Orphanet):
| Parent Diseases: |
Adolescent-onset epilepsy syndrome
-Rare genetic disease -Rare neurologic disease Childhood-onset epilepsy syndrome -Rare genetic disease -Rare neurologic disease Familial partial epilepsy -Rare genetic disease -Rare neurologic disease Infantile epilepsy syndrome -Rare genetic disease -Rare neurologic disease |
Symptom Information:
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(HPO:0002121) | Absence seizures | 62 / 7739 | ||||
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(HPO:0002069) | Generalized tonic-clonic seizures | 96 / 7739 | ||||
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(HPO:0002373) | Febrile seizures | 37 / 7739 | ||||
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(HPO:0010819) | Atonic seizures | 18 / 7739 | ||||
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(HPO:0000006) | Autosomal dominant inheritance | 2518 / 7739 | ||||
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(HPO:0003829) | Incomplete penetrance | 85 / 7739 |
Associated genes:
ClinVar (via SNiPA)
| Gene symbol | Variation | Clinical significance | Reference |
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