Symptom Information: Sort according to HPO 

1
 (HPO:0000505) Visual impairment 20598281 IBIS 297 / 7739
2
 (HPO:0000508) Ptosis 20598281 IBIS 459 / 7739
3
 (HPO:0000602) Ophthalmoplegia 20598281 IBIS 56 / 7739
4
 (HPO:0000639) Nystagmus 20598281 IBIS 555 / 7739
5
 (HPO:0000648) Optic atrophy 20598281 IBIS 238 / 7739
6
 (HPO:0001251) Ataxia 20598281 IBIS 413 / 7739
7
 (HPO:0001260) Dysarthria 20598281 IBIS 329 / 7739
8
 (HPO:0001263) Global developmental delay 20598281 IBIS 853 / 7739
9
 (HPO:0001284) Areflexia 20598281 IBIS 198 / 7739
10
 (HPO:0001349) Facial diplegia 20598281 IBIS 16 / 7739
11
 (HPO:0001508) Failure to thrive 20598281 IBIS 454 / 7739
12
 (HPO:0002151) Increased serum lactate 20598281 IBIS 92 / 7739
13
 (HPO:0002376) Developmental regression 20598281 IBIS 74 / 7739
14
 (HPO:0002490) Increased CSF lactate 20598281 IBIS 28 / 7739
15
 (HPO:0002590) Paralytic ileus 20598281 IBIS 4 / 7739
16
 (HPO:0002936) Distal sensory impairment 20598281 IBIS 96 / 7739
17
 (HPO:0003202) Skeletal muscle atrophy 20598281 IBIS 281 / 7739
18
 (OMIM) Chewing/swallowing difficulties 20598281 IBIS 3 / 7739
19
 (HPO:0001252) Muscular hypotonia 20598281 IBIS 990 / 7739
20
 (HPO:0001324) Muscle weakness 20598281 IBIS 859 / 7739
21
 (OMIM) Brain imaging shows lesions in the thalami, brainstem, and cerebellum 20598281 IBIS 1 / 7739
22
 (OMIM) Fibroblasts show decreased activity of mitochondrial respiratory complex I, complex III, complex IV, and complex V 20598281 IBIS 2 / 7739
23
 (HPO:0001271) Polyneuropathy 20598281 IBIS 56 / 7739
24
 (HPO:0011923) Decreased activity of mitochondrial complex I 20598281 IBIS 35 / 7739
25
 (HPO:0011924) Decreased activity of mitochondrial complex III 20598281 IBIS 22 / 7739
26
 (HPO:0008347) Decreased activity of mitochondrial complex IV 20598281 IBIS 31 / 7739
27
 (HPO:0011925) Decreased activity of mitochondrial ATP synthase complex 20598281 IBIS 10 / 7739