Decreased activity of mitochondrial ATP synthase complex

Symptom Information:

Symptom ID: HPO:0011925
Synonyms:
Respiratory complex deficiency, ATPase deficiency [HPO:0011925]
Quality:
Cross references:
Is a (Direct Parents):
HPO         Decreased activity of mitochondrial respiratory chain
Is a (Whole tree): HPO:
All(HPO:0000001)
    Phenotypic abnormality(HPO:0000118)
       Abnormality of metabolism/homeostasis(HPO:0001939)
          Abnormality of cell physiology(HPO:0011017)
             Abnormality of the mitochondrion(HPO:0012103)
                Abnormality of mitochondrial metabolism(HPO:0003287)
                   Abnormal activity of mitochondrial respiratory chain(HPO:0011922)
                      Decreased activity of mitochondrial respiratory chain(HPO:0008972)
                         Decreased activity of mitochondrial ATP synthase complex(HPO:0011925)
MedDRA:
Database Frequency: 10 / 7739
Resource:

All diseases associated with this symptom:

Autosomal recessive spastic paraplegia type 55 (Orphanet:320375)
Combined oxidative phosphorylation defect type 11 (Orphanet:324535)
Combined oxidative phosphorylation defect type 15 (Orphanet:319524)
Combined oxidative phosphorylation defect type 2 (Orphanet:254920)
Combined oxidative phosphorylation defect type 7 (Orphanet:254930)
Combined oxidative phosphorylation defect type 9 (Orphanet:319509)
Hepatoencephalopathy due to combined oxidative phosphorylation deficiency type 1 (Orphanet:137681)
Hypotonia with lactic acidemia and hyperammonemia (Orphanet:137908)
MITOCHONDRIAL COMPLEX V (ATP SYNTHASE) DEFICIENCY, NUCLEAR TYPE 3 (OMIM:614053)
Mitochondrial encephalo-cardio-myopathy due to TMEM70 deficiency (Orphanet:1194)