Decreased activity of mitochondrial respiratory chain

Symptom Information:

Symptom ID: HPO:0008972
Synonyms:
DECREASED ACTIVITIES OF MITOCHONDRIAL-ENCODED RESPIRATORY CHAIN COMPLEXES [HPO:0008972]
DECREASED ACTIVITY OF MITOCHONDRIAL RESPIRATORY COMPLEXES [HPO:0008972]
Decreased activities of mitochondrial-encoded respiratory chain complexes [OMIM:Decreased activities of mitochondrial-encoded respiratory chain complexes]
Decreased activity of mitochondrial respiratory complexes [OMIM:Decreased activity of mitochondrial respiratory complexes]
Quality:
Cross references:
OMIM: "Decreased activities of mitochondrial-encoded respiratory chain complexes" [OMIM:Decreased activities of mitochondrial-encoded respiratory chain complexes]
OMIM: "Decreased activity of mitochondrial respiratory complexes" [OMIM:Decreased activity of mitochondrial respiratory complexes]
Is a (Direct Parents):
HPO         Abnormal activity of mitochondrial respiratory chain
Is a (Whole tree): HPO:
All(HPO:0000001)
    Phenotypic abnormality(HPO:0000118)
       Abnormality of metabolism/homeostasis(HPO:0001939)
          Abnormality of cell physiology(HPO:0011017)
             Abnormality of the mitochondrion(HPO:0012103)
                Abnormality of mitochondrial metabolism(HPO:0003287)
                   Abnormal activity of mitochondrial respiratory chain(HPO:0011922)
                      Decreased activity of mitochondrial respiratory chain(HPO:0008972)
MedDRA:
Database Frequency: 34 / 7739
Resource:

All diseases associated with this symptom:

Acyl-CoA dehydrogenase 9 deficiency (Orphanet:99901)
Alpers syndrome (Orphanet:726)
Autosomal recessive spastic ataxia with leukoencephalopathy (Orphanet:314603)
Autosomal recessive spastic paraplegia type 55 (Orphanet:320375)
Autosomal recessive spastic paraplegia type 7 (Orphanet:99013)
Behr syndrome (Orphanet:1239)
Combined oxidative phosphorylation defect type 11 (Orphanet:324535)
Combined oxidative phosphorylation defect type 14 (Orphanet:319519)
Combined oxidative phosphorylation defect type 17 (Orphanet:369913)
Combined oxidative phosphorylation defect type 8 (Orphanet:319504)
Combined oxidative phosphorylation defect type 9 (Orphanet:319509)
Congenital cataract - progressive muscular hypotonia - hearing loss - developmental delay (Orphanet:330054)
Congenital cataract-hypertrophic cardiomyopathy-mitochondrial myopathy syndrome (Orphanet:1369)
Congenital lactic acidosis, Saguenay-Lac-St. Jean type (Orphanet:70472)
Fatal multiple mitochondrial dysfunction syndrome (Orphanet:289573)
GRACILE syndrome (Orphanet:53693)
Hypotonia with lactic acidemia and hyperammonemia (Orphanet:137908)
Infantile hypertrophic cardiomyopathy due to MRPL44 deficiency (Orphanet:352563)
Leber plus disease (Orphanet:99718)
Leigh syndrome with leukodystrophy (Orphanet:255241)
Leigh syndrome with nephrotic syndrome (Orphanet:255249)
Lethal infantile mitochondrial myopathy (Orphanet:254857)
Leukoencephalopathy - thalamus and brainstem anomalies - high lactate (Orphanet:314051)
MERRF (Orphanet:551)
MULTIPLE MITOCHONDRIAL DYSFUNCTIONS SYNDROME 1 (OMIM:605711)
MULTIPLE MITOCHONDRIAL DYSFUNCTIONS SYNDROME 2 (OMIM:614299)
Mitochondrial DNA depletion syndrome, encephalomyopathic form with methylmalonic aciduria (Orphanet:1933)
Mitochondrial DNA depletion syndrome, hepatocerebral form due to DGUOK deficiency (Orphanet:279934)
Mitochondrial DNA depletion syndrome, myopathic form (Orphanet:254875)
Mitochondrial hypertrophic cardiomyopathy with lactic acidosis due to MTO1 deficiency (Orphanet:314637)
NARP syndrome (Orphanet:644)
Navajo neurohepatopathy (Orphanet:255229)
Necrotizing encephalomyelopathy, subacute, of Leigh, adult (OMIM:161700)
Pontocerebellar hypoplasia type 6 (Orphanet:166073)