Increased CSF lactate

Symptom Information:

Symptom ID: HPO:0002490
Synonyms:
Increased cerebrospinal fluid lactate [HPO:0002490]
Increased CSF lactic acid [HPO:0002490]
Increased CSF lactate [OMIM:Increased CSF lactate]
Increased CSF lactic acid [OMIM:Increased CSF lactic acid]
Increased cerebrospinal fluid lactate [OMIM:Increased cerebrospinal fluid lactate]
CSF lactate increased [MedDRA:10059750]
Quality:
Cross references:
OMIM: "Increased CSF lactate" [OMIM:Increased CSF lactate]
OMIM: "Increased CSF lactic acid" [OMIM:Increased CSF lactic acid]
OMIM: "Increased cerebrospinal fluid lactate" [OMIM:Increased cerebrospinal fluid lactate]
Is a (Direct Parents):
MedDRA Cerebrospinal fluid tests (excl microbiology)
HPO         Abnormality of the cerebrospinal fluid
Is a (Whole tree): HPO:
All(HPO:0000001)
    Phenotypic abnormality(HPO:0000118)
       Abnormality of the nervous system(HPO:0000707)
          Abnormality of nervous system morphology(HPO:0012639)
             Morphological abnormality of the central nervous system(HPO:0002011)
                Abnormality of the cerebrospinal fluid(HPO:0002921)
                   Increased CSF lactate(HPO:0002490)
MedDRA:
Investigations(MedDRA:10022891)
    Neurological, special senses and psychiatric investigations(MedDRA:10029295)
       Cerebrospinal fluid tests (excl microbiology)(MedDRA:10008183)
          Increased CSF lactate(HPO:0002490)
Database Frequency: 28 / 7739
Resource:

All diseases associated with this symptom:

Alpers syndrome (Orphanet:726)
CARDIOENCEPHALOMYOPATHY, FATAL INFANTILE, DUE TO CYTOCHROME c OXIDASEDEFICIENCY 1 (OMIM:604377)
Combined oxidative phosphorylation defect type 11 (Orphanet:324535)
Combined oxidative phosphorylation defect type 13 (Orphanet:319514)
Combined oxidative phosphorylation defect type 14 (Orphanet:319519)
Combined oxidative phosphorylation defect type 15 (Orphanet:319524)
Combined oxidative phosphorylation defect type 7 (Orphanet:254930)
Congenital lactic acidosis, Saguenay-Lac-St. Jean type (Orphanet:70472)
Fatal infantile cytochrome C oxidase deficiency (Orphanet:1561)
Hepatoencephalopathy due to combined oxidative phosphorylation deficiency type 1 (Orphanet:137681)
Hypertrophic cardiomyopathy and renal tubular disease due to mitochondrial DNA mutation (Orphanet:324525)
Hyperuricemia-pulmonary hypertension-renal failure-alkalosis syndrome (Orphanet:363694)
Isolated NADH-CoQ reductase deficiency (Orphanet:2609)
Isolated cytochrome C oxidase deficiency (Orphanet:254905)
LEBER OPTIC ATROPHY AND DYSTONIA (OMIM:500001)
Leigh syndrome (Orphanet:506)
Leukoencephalopathy - thalamus and brainstem anomalies - high lactate (Orphanet:314051)
Leukoencephalopathy with brain stem and spinal cord involvement - lactate elevation (Orphanet:137898)
MELAS (Orphanet:550)
MERRF (Orphanet:551)
MITOCHONDRIAL SHORT-CHAIN ENOYL-CoA HYDRATASE 1 DEFICIENCY (OMIM:616277)
Maternally-inherited Leigh syndrome (Orphanet:255210)
Pontocerebellar hypoplasia type 6 (Orphanet:166073)
Progressive demyelinating neuropathy with bilateral striatal necrosis (Orphanet:217396)
Pyruvate dehydrogenase E1-alpha deficiency (Orphanet:79243)
Pyruvate dehydrogenase E3-binding protein deficiency (Orphanet:255182)
Severe X-linked mitochondrial encephalomyopathy (Orphanet:238329)
Sporadic Leigh syndrome (Orphanet:255199)