Decreased activity of mitochondrial complex III

Symptom Information:

Symptom ID: HPO:0011924
Synonyms:
Respiratory complex III deficiency [HPO:0011924]
Quality:
Cross references:
Is a (Direct Parents):
HPO         Decreased activity of mitochondrial respiratory chain
Is a (Whole tree): HPO:
All(HPO:0000001)
    Phenotypic abnormality(HPO:0000118)
       Abnormality of metabolism/homeostasis(HPO:0001939)
          Abnormality of cell physiology(HPO:0011017)
             Abnormality of the mitochondrion(HPO:0012103)
                Abnormality of mitochondrial metabolism(HPO:0003287)
                   Abnormal activity of mitochondrial respiratory chain(HPO:0011922)
                      Decreased activity of mitochondrial respiratory chain(HPO:0008972)
                         Decreased activity of mitochondrial complex III(HPO:0011924)
MedDRA:
Database Frequency: 22 / 7739
Resource:

All diseases associated with this symptom:

Alpers syndrome (Orphanet:726)
Autosomal recessive spastic paraplegia type 7 (Orphanet:99013)
Combined oxidative phosphorylation defect type 11 (Orphanet:324535)
Combined oxidative phosphorylation defect type 13 (Orphanet:319514)
Combined oxidative phosphorylation defect type 7 (Orphanet:254930)
Combined oxidative phosphorylation defect type 8 (Orphanet:319504)
Encephalopathy-hypertrophic cardiomyopathy-renal tubular disease syndrome (Orphanet:319678)
Fatal mitochondrial disease due to combined oxidative phosphorylation deficiency 3 (Orphanet:168566)
GRACILE syndrome (Orphanet:53693)
Hepatoencephalopathy due to combined oxidative phosphorylation deficiency type 1 (Orphanet:137681)
Hereditary myopathy with lactic acidosis due to ISCU deficiency (Orphanet:43115)
Hyperuricemia-pulmonary hypertension-renal failure-alkalosis syndrome (Orphanet:363694)
Hypotonia with lactic acidemia and hyperammonemia (Orphanet:137908)
Leigh syndrome with nephrotic syndrome (Orphanet:255249)
Lethal infantile mitochondrial myopathy (Orphanet:254857)
Leukoencephalopathy - thalamus and brainstem anomalies - high lactate (Orphanet:314051)
Myopathy, lactic acidosis, and sideroblastic anemia 2; MLASA2 (OMIM:613561)
Navajo neurohepatopathy (Orphanet:255229)
Pontocerebellar hypoplasia type 6 (Orphanet:166073)
Pyruvate dehydrogenase lipoic acid synthetase deficiency (OMIM:614462)
Pyruvate dehydrogenase phosphatase deficiency (Orphanet:79246)
Severe X-linked mitochondrial encephalomyopathy (Orphanet:238329)