Progressive spastic paraplegia

Symptom Information:

Symptom ID: HPO:0007020
Synonyms:
Progressive spastic paraplegia [OMIM:Progressive spastic paraplegia]
Spastic paraplegia, progressive [OMIM:Spastic paraplegia, progressive]
Quality:
Cross references:
OMIM: "Progressive spastic paraplegia" [OMIM:Progressive spastic paraplegia]
OMIM: "Spastic paraplegia, progressive" [OMIM:Spastic paraplegia, progressive]
Is a (Direct Parents):
HPO         Spastic paraplegia
Is a (Whole tree): HPO:
All(HPO:0000001)
    Phenotypic abnormality(HPO:0000118)
       Abnormality of the nervous system(HPO:0000707)
          Abnormality of nervous system physiology(HPO:0012638)
             Abnormality of central motor function(HPO:0011442)
                Abnormal pyramidal signs(HPO:0007256)
                   Hypertonia(HPO:0001276)
                      Spasticity(HPO:0001257)
                         Lower limb spasticity(HPO:0002061)
                            Spastic paraplegia(HPO:0001258)
                               Progressive spastic paraplegia(HPO:0007020)
                   Weakness due to upper motor neuron dysfunction(HPO:0010549)
                      Paraplegia/paraparesis(HPO:0010551)
                         Paraplegia(HPO:0010550)
                            Spastic paraplegia(HPO:0001258)
                               Progressive spastic paraplegia(HPO:0007020)
MedDRA:
Database Frequency: 5 / 7739
Resource:

All diseases associated with this symptom:

Autosomal recessive spastic paraplegia type 39 (Orphanet:139480)
Macrocephaly - spastic paraplegia - dysmorphism (Orphanet:2429)
Miller-Dieker syndrome (Orphanet:531)
Paraplegia - brachydactyly - cone-shaped epiphysis (Orphanet:2823)
Syndromic X-linked intellectual deficit due to JARID1C mutation (Orphanet:85279)