Generalized hyperkeratosis

Symptom Information:

Symptom ID: HPO:0005595
Synonyms:
Hyperkeratosis, generalized [HPO:0005595]
Hyperkeratosis [Orphanet:23090]
Hyperkeratosis (disorder) [Orphanet:23090]
Hyperkeratosis (morphologic abnormality) [Orphanet:23090]
Hyperkeratosis, generalized [OMIM:Hyperkeratosis, generalized]
Hyperkeratosis/ainhum/hyperkeratotic skin fissures [Orphanet:23090]
Hyperkeratosis [MedDRA:10020649]
Acquired keratoderma [MedDRA:10020649]
Callosities [MedDRA:10020649]
Callosity [MedDRA:10020649]
Callus [MedDRA:10020649]
Corns [MedDRA:10020649]
Corns and callosities [MedDRA:10020649]
Cutaneous horn [MedDRA:10020649]
Erythrokeratoderma [MedDRA:10020649]
Foot callus [MedDRA:10020649]
Hard corn [MedDRA:10020649]
Keratoderma [MedDRA:10020649]
Keratoderma, acquired [MedDRA:10020649]
Keratosis [MedDRA:10020649]
Skin keratosis [MedDRA:10020649]
Soft corn [MedDRA:10020649]
Tyloma [MedDRA:10020649]
Tylosis [MedDRA:10020649]
Skin callus [MedDRA:10020649]
Foot callus [OMIM:Foot callus]
Hyperkeratosis (especially extensor surfaces) [OMIM:Hyperkeratosis (especially extensor surfaces)]
Hyperkeratosis (in some patients) [OMIM:Hyperkeratosis (in some patients)]
Hyperkeratosis (palms, soles, elbows, knees) [OMIM:Hyperkeratosis (palms, soles, elbows, knees)]
Keratoderma (palms and soles) [OMIM:Keratoderma (palms and soles)]
Tylosis [OMIM:Tylosis]
Ainhum [MedDRA:10001524]
Ainhum (disorder) [Orphanet:23090]
Ainhum [Orphanet:23090]
Quality:
Cross references:
HPO:0000962 "Hyperkeratosis" [Orphanet:23090]
Orphanet:23090 "Hyperkeratosis/ainhum/hyperkeratotic skin fissures" [Orphanet:23090]
OMIM: "Hyperkeratosis, generalized" [OMIM:Hyperkeratosis, generalized]
OMIM: "Foot callus" [OMIM:Foot callus]
OMIM: "Hyperkeratosis (especially extensor surfaces)" [OMIM:Hyperkeratosis (especially extensor surfaces)]
OMIM: "Hyperkeratosis (in some patients)" [OMIM:Hyperkeratosis (in some patients)]
OMIM: "Hyperkeratosis (palms, soles, elbows, knees)" [OMIM:Hyperkeratosis (palms, soles, elbows, knees)]
OMIM: "Keratoderma (palms and soles)" [OMIM:Keratoderma (palms and soles)]
OMIM: "Tylosis" [OMIM:Tylosis]
UMLS:C0870082 "Hyperkeratosis" [Orphanet:23090]
UMLS:C0001860 "Ainhum" [Orphanet:23090]
Is a (Direct Parents):
Orphanet Abnormality of the skin
HPO         Hyperkeratosis
Orphanet Hyperkeratosis
MedDRA Hyperkeratoses
Is a (Whole tree): HPO:
All(HPO:0000001)
    Phenotypic abnormality(HPO:0000118)
       Abnormality of the integument(HPO:0001574)
          Abnormality of the skin(HPO:0000951)
             Generalized abnormality of skin(HPO:0011354)
                Abnormality of skin morphology(HPO:0011121)
                   Thickened skin(HPO:0001072)
                      Epidermal thickening(HPO:0011368)
                         Hyperkeratosis(HPO:0000962)
                            Generalized hyperkeratosis(HPO:0005595)
MedDRA:
Skin and subcutaneous tissue disorders(MedDRA:10040785)
    Cornification and dystrophic skin disorders(MedDRA:10011063)
       Hyperkeratoses(MedDRA:10020648)
          Generalized hyperkeratosis(HPO:0005595)
Database Frequency: 14 / 7739
Resource:

All diseases associated with this symptom:

ALACRIMA, ACHALASIA, AND MENTAL RETARDATION SYNDROME (OMIM:615510)
Ankylosing vertebral hyperostosis with tylosis (Orphanet:2206)
Autosomal dominant Charcot-Marie-Tooth disease type 2B (Orphanet:99936)
CARDIOFACIOCUTANEOUS SYNDROME 1 (OMIM:115150)
Erythrokeratodermia variabilis (Orphanet:317)
Fetal Gaucher disease (Orphanet:85212)
Insulin-resistance syndrome type A (Orphanet:2297)
KERATITIS-ICHTHYOSIS-DEAFNESS SYNDROME, AUTOSOMAL DOMINANT (OMIM:148210)
Leprechaunism (Orphanet:508)
Odonto-onycho-dermal dysplasia (Orphanet:2721)
Progressive symmetric erythrokeratodermia (Orphanet:316)
Transgrediens et progrediens palmoplantar keratoderma (Orphanet:495)
Tyrosinemia type 2 (Orphanet:28378)
Werner syndrome (Orphanet:902)