Myoclonus

Symptom Information:

Symptom ID: HPO:0001336
Synonyms:
Myoclonic jerks [HPO:0001336]
Myoclonus (finding) [Orphanet:43270]
Myoclonic disorder (disorder) [Orphanet:43270]
Myoclonia (finding) [Orphanet:43270]
Myoclonus [Orphanet:43270]
Myoclonia [Orphanet:43270]
Myoclonic jerks [OMIM:Myoclonic jerks]
Myoclonus [OMIM:Myoclonus]
Myoclonus/fasciculations [Orphanet:43270]
Myoclonus [MedDRA:10028622]
Myclonic jerks [MedDRA:10028622]
Myoclonic jerks [MedDRA:10028622]
Palatal myoclonus [MedDRA:10028622]
Negative myoclonus [MedDRA:10028622]
Positive myoclonus [MedDRA:10028622]
Hypnagogic myoclonus [MedDRA:10028622]
Myoclonic jerks (1 patient) [OMIM:Myoclonic jerks (1 patient)]
Myoclonic jerks (less common) [OMIM:Myoclonic jerks (less common)]
Myoclonus (in 1 family) [OMIM:Myoclonus (in 1 family)]
Myoclonus (in a subset of patients) [OMIM:Myoclonus (in a subset of patients)]
Myoclonus (less common) [OMIM:Myoclonus (less common)]
Myoclonus (subtype 3A) [OMIM:Myoclonus (subtype 3A)]
Myoclonus (type I and type II, infantile and juvenile) [OMIM:Myoclonus (type I and type II, infantile and juvenile)]
Quality:
Cross references:
HPO:0002169 "Clonus" [Orphanet:43270]
Orphanet:43270 "Myoclonus/fasciculations" [Orphanet:43270]
OMIM: "Myoclonic jerks" [OMIM:Myoclonic jerks]
OMIM: "Myoclonus" [OMIM:Myoclonus]
OMIM: "Myoclonic jerks (1 patient)" [OMIM:Myoclonic jerks (1 patient)]
OMIM: "Myoclonic jerks (less common)" [OMIM:Myoclonic jerks (less common)]
OMIM: "Myoclonus (in 1 family)" [OMIM:Myoclonus (in 1 family)]
OMIM: "Myoclonus (in a subset of patients)" [OMIM:Myoclonus (in a subset of patients)]
OMIM: "Myoclonus (less common)" [OMIM:Myoclonus (less common)]
OMIM: "Myoclonus (subtype 3A)" [OMIM:Myoclonus (subtype 3A)]
OMIM: "Myoclonus (type I and type II, infantile and juvenile)" [OMIM:Myoclonus (type I and type II, infantile and juvenile)]
UMLS:C0027066 "Myoclonus" [HPO:0001336]
UMLS:C0027066 "Myoclonus" [Orphanet:43270]
UMLS:C0027063 "Myoclonia" [Orphanet:43270]
Is a (Direct Parents):
HPO         Involuntary movements
HPO         Cortical myoclonus
MedDRA Neurological signs and symptoms NEC
Orphanet Abnormality of movement
Is a (Whole tree): HPO:
All(HPO:0000001)
    Phenotypic abnormality(HPO:0000118)
       Abnormality of the musculature(HPO:0003011)
          Abnormality of muscle physiology(HPO:0011804)
             Involuntary movements(HPO:0004305)
                Myoclonus(HPO:0001336)
       Abnormality of the nervous system(HPO:0000707)
          Abnormality of nervous system physiology(HPO:0012638)
             Abnormality of movement(HPO:0100022)
                Involuntary movements(HPO:0004305)
                   Myoclonus(HPO:0001336)
MedDRA:
Nervous system disorders(MedDRA:10029205)
    Neurological disorders NEC(MedDRA:10029305)
       Neurological signs and symptoms NEC(MedDRA:10029306)
          Myoclonus(HPO:0001336)
Database Frequency: 115 / 7739
Resource:

All diseases associated with this symptom:

ALZHEIMER DISEASE 3 (OMIM:607822)
ATAXIA WITH MYOCLONIC EPILEPSY AND PRESENILE DEMENTIA (OMIM:208700)
ATAXIA-TELANGIECTASIA (OMIM:208900)
Action myoclonus - renal failure syndrome (Orphanet:163696)
Adenylosuccinate lyase deficiency (Orphanet:46)
Alpers syndrome (Orphanet:726)
Alpha-N-acetylgalactosaminidase deficiency (Orphanet:3137)
Alpha-N-acetylgalactosaminidase deficiency type 1 (Orphanet:79279)
Alpha-N-acetylgalactosaminidase deficiency type 3 (Orphanet:79281)
Alström syndrome (Orphanet:64)
Amish infantile epilepsy syndrome (Orphanet:171714)
Aromatic L-amino acid decarboxylase deficiency (Orphanet:35708)
Ataxia-telangiectasia (Orphanet:100)
Atypical Gaucher disease due to saposin C deficiency (Orphanet:309252)
Atypical Rett syndrome (Orphanet:3095)
Autosomal recessive ataxia due to ubiquinone deficiency (Orphanet:139485)
Autosomal recessive cerebellar ataxia - saccadic intrusion (Orphanet:95434)
Autosomal recessive dopa-responsive dystonia (Orphanet:101150)
Autosomal recessive dopa-responsive dystonia (Orphanet:101150)
Autosomal recessive spastic paraplegia type 48 (Orphanet:306511)
Behavioral variant of frontotemporal dementia (Orphanet:275864)
CEREBELLOPARENCHYMAL DISORDER V (OMIM:213400)
CLN1 disease (Orphanet:228329)
CLN2 disease (Orphanet:228349)
CLN3 disease (Orphanet:228346)
CLN4A disease (Orphanet:228340)
CLN4B disease (Orphanet:228343)
CLN5 disease (Orphanet:228360)
CLN8 disease (Orphanet:228354)
CONVULSIVE DISORDER, FAMILIAL, WITH PRENATAL OR EARLY ONSET (OMIM:217200)
Combined oxidative phosphorylation defect type 11 (Orphanet:324535)
Combined oxidative phosphorylation defect type 14 (Orphanet:319519)
Creutzfeldt-Jakob disease (Orphanet:204)
D-glyceric aciduria (Orphanet:941)
DYSTONIA 15, MYOCLONIC (OMIM:607488)
DYSTONIA 23 (OMIM:614860)
Dentatorubral pallidoluysian atrophy (Orphanet:101)
Dihydropteridine reductase deficiency (Orphanet:226)
Dopa-responsive dystonia due to sepiapterin reductase deficiency (Orphanet:70594)
ENCEPHALOPATHY, PROGRESSIVE, WITH OR WITHOUT LIPODYSTROPHY (OMIM:615924)
EPILEPSY, FAMILIAL ADULT MYOCLONIC, 2 (OMIM:607876)
EPILEPSY, FAMILIAL ADULT MYOCLONIC, 3 (OMIM:613608)
EPILEPSY, IDIOPATHIC GENERALIZED, SUSCEPTIBILITY TO, 7 (OMIM:604827)
EPILEPSY, MYOCLONIC JUVENILE (OMIM:254770)
EPILEPSY, PROGRESSIVE MYOCLONIC 7 (OMIM:616187)
EPILEPTIC ENCEPHALOPATHY, EARLY INFANTILE, 2 (OMIM:300672)
Early-onset spastic ataxia-neuropathy syndrome (Orphanet:313772)
Encephalopathy due to GLUT1 deficiency (Orphanet:71277)
Encephalopathy due to prosaposin deficiency (Orphanet:139406)
Familial cortical myoclonus (Orphanet:319189)
Familial encephalopathy with neuroserpin inclusion bodies (Orphanet:85110)
Fatal familial insomnia (Orphanet:466)
GTP cyclohydrolase I deficiency (Orphanet:2102)
Gaucher disease type 2 (Orphanet:77260)
Gaucher disease type 3 (Orphanet:77261)
Gerstmann-Straussler-Scheinker syndrome (Orphanet:356)
Glycine encephalopathy (Orphanet:407)
Guanidinoacetate methyltransferase deficiency (Orphanet:382)
HYPEREKPLEXIA, HEREDITARY 1 (OMIM:149400)
Hereditary hyperekplexia (Orphanet:3197)
Hereditary myoclonus - progressive distal muscular atrophy (Orphanet:2590)
Hyperinsulinism-hyperammonemia syndrome (Orphanet:35878)
Hyperornithinemia-hyperammonemia-homocitrullinuria (Orphanet:415)
Inherited Creutzfeldt-Jakob disease (Orphanet:282166)
Isolated succinate-CoQ reductase deficiency (Orphanet:3208)
Kufor-Rakeb syndrome (Orphanet:306674)
Lafora disease (Orphanet:501)
Late infantile neuronal ceroid lipofuscinosis (Orphanet:168491)
Leber plus disease (Orphanet:99718)
Leigh syndrome (Orphanet:506)
Leprechaunism (Orphanet:508)
MELAS (Orphanet:550)
MENTAL RETARDATION, AUTOSOMAL DOMINANT 31 (OMIM:616158)
MENTAL RETARDATION, AUTOSOMAL RECESSIVE 6 (OMIM:611092)
MERRF (Orphanet:551)
MUSCULAR DYSTROPHY-DYSTROGLYCANOPATHY (CONGENITAL WITH BRAIN AND EYEANOMALIES), TYPE A, 3 (OMIM:253280)
Microcephaly-capillary malformation syndrome (Orphanet:294016)
Myoclonus - cerebellar ataxia - deafness (Orphanet:2589)
Myoclonus-dystonia syndrome (Orphanet:36899)
NEUROBLASTOMA, SUSCEPTIBILITY TONEUROBLASTOMA, SUSCEPTIBILITY TO, 1, INCLUDED (OMIM:256700)
NYSTAGMUS, MYOCLONIC (OMIM:310800)
Nasu-Hakola disease (Orphanet:2770)
Navajo neurohepatopathy (Orphanet:255229)
Necrotizing encephalomyelopathy, subacute, of Leigh, adult (OMIM:161700)
Neonatal hemochromatosis (Orphanet:446)
Neuroblastoma (Orphanet:635)
Neurodegeneration due to 3-hydroxyisobutyryl-CoA hydrolase deficiency (Orphanet:88639)
Orofaciodigital syndrome type 3 (Orphanet:2752)
PARASOMNIA, SLEEP BRUXISM TYPE (OMIM:606840)
POLYMYOCLONUS, INFANTILE (OMIM:263550)
Parkinsonim due to ATP13A2 deficiency (Orphanet:314632)
Permanent neonatal diabetes mellitus - pancreatic and cerebellar agenesis (Orphanet:65288)
Pontocerebellar hypoplasia type 4 (Orphanet:166063)
Primary dystonia, DYT6 type (Orphanet:98806)
Progressive myoclonic epilepsy type 6 (Orphanet:280620)
Progressive myoclonic epilepsy with dystonia (Orphanet:352596)
Proximal tubulopathy - diabetes mellitus - cerebellar ataxia (Orphanet:3390)
Pyridoxal phosphate-responsive seizures (Orphanet:79096)
Pyruvate carboxylase deficiency (Orphanet:3008)
RESTLESS LEGS SYNDROME, SUSCEPTIBILITY TO, 1 (OMIM:102300)
RFT1-CDG (Orphanet:244310)
Ramsay-Hunt syndrome (Orphanet:3020)
Sensory ataxic neuropathy-dysarthria-ophthalmoparesis (Orphanet:70595)
Severe neonatal-onset encephalopathy with microcephaly (Orphanet:209370)
Sialidosis type 1 (Orphanet:812)
Spinocerebellar ataxia type 17 (Orphanet:98759)
Spinocerebellar ataxia type 19/22 (Orphanet:98772)
Spinocerebellar ataxia type 2 (Orphanet:98756)
Spinocerebellar ataxia with epilepsy (Orphanet:254881)
Thyrocerebrorenal syndrome (Orphanet:3327)
Unverricht-Lundborg disease (Orphanet:308)
Wolfram syndrome 1 (OMIM:222300)
X-linked dystonia-parkinsonism (Orphanet:53351)
X-linked intellectual disability due to GRIA3 anomalies (Orphanet:364028)
Young adult-onset Parkinsonism (Orphanet:2828)