|
1
|
(HPO:0002061)
|
Lower limb spasticity |
Very frequent [IBIS]
|
|
17160902
|
IBIS
|
56 / 7739
|
|
2
|
(HPO:0000012)
|
Urinary urgency |
Frequent [IBIS]
|
70% (n=10)
|
23455931
|
IBIS
|
35 / 7739
|
|
3
|
(HPO:0002166)
|
Impaired vibration sensation in the lower limbs |
Frequent [IBIS]
|
|
23455931
|
IBIS
|
26 / 7739
|
|
4
|
(HPO:0000020)
|
Urinary incontinence |
|
|
23455931
|
IBIS
|
75 / 7739
|
|
5
|
(HPO:0001258)
|
Spastic paraplegia |
|
|
23455931
|
IBIS
|
97 / 7739
|
|
6
|
(HPO:0001347)
|
Hyperreflexia |
|
|
17160902
|
IBIS
|
363 / 7739
|
|
7
|
(HPO:0002064)
|
Spastic gait |
|
|
17160902
|
IBIS
|
46 / 7739
|
|
8
|
(HPO:0002314)
|
Degeneration of the lateral corticospinal tracts |
|
|
23085491
|
IBIS
|
9 / 7739
|
|
9
|
(HPO:0002839)
|
Urinary bladder sphincter dysfunction |
|
|
24824269
|
IBIS
|
34 / 7739
|
|
10
|
(HPO:0003487)
|
Babinski sign |
|
|
17160902
|
IBIS
|
179 / 7739
|
|
11
|
(HPO:0006986)
|
Upper limb spasticity |
rare [HPO:skoehler]
|
|
23455931
|
IBIS
|
15 / 7739
|
|
12
|
(HPO:0007340)
|
Lower limb muscle weakness |
|
|
17160902
|
IBIS
|
61 / 7739
|
|
13
|
(HPO:0003587)
|
Insidious onset |
|
|
24824269
|
IBIS
|
11 / 7739
|
|
14
|
(HPO:0003676)
|
Progressive disorder |
|
|
17160902
|
IBIS
|
148 / 7739
|
|
15
|
(HPO:0001257)
|
Spasticity |
|
|
23455931
|
IBIS
|
251 / 7739
|
|
16
|
(HPO:0003419)
|
Low back pain |
|
|
23455931
|
IBIS
|
6 / 7739
|
|
17
|
(HPO:0002829)
|
Arthralgia |
|
|
23455931
|
IBIS
|
79 / 7739
|
|
18
|
(HPO:0003202)
|
Skeletal muscle atrophy |
|
|
17160902
|
IBIS
|
281 / 7739
|
|
19
|
(HPO:0008969)
|
Leg muscle stiffness |
|
|
24824269
|
IBIS
|
5 / 7739
|
|
20
|
(HPO:0012708)
|
Reduced brain N-acetyl aspartate level by MRS |
|
|
24824269
|
IBIS
|
2 / 7739
|
|
21
|
(HPO:0002062)
|
Morphological abnormality of the pyramidal tract |
|
|
24824269
|
IBIS
|
24 / 7739
|
|
22
|
(HPO:0002500)
|
Abnormality of the cerebral white matter |
|
|
24824269
|
IBIS
|
73 / 7739
|